利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

184 条记录 (耗时 0.03 秒)

    Method of treating or preventing immune mediated disorders and pharmaceutical formulation for use therein
    1.
    发明授权
    Method of treating or preventing immune mediated disorders and pharmaceutical formulation for use therein 有权
    治疗或预防免疫介导的病症的方法及其中使用的药物制剂

    公开(公告)号：US07923440B2

    公开(公告)日：2011-04-12

    申请号：US10517686

    申请日：2003-06-11

    申请人： Evert Johannes Bunschoten ,  Herman Jan Tijmen Coelingh Bennink ,  Christian Franz Holinka

    发明人： Evert Johannes Bunschoten ,  Herman Jan Tijmen Coelingh Bennink ,  Christian Franz Holinka

    IPC分类号： A01N45/00 ,  A61K31/56

    CPC分类号： A61K31/565 ,  Y10S514/874 ,  Y10S514/903

    摘要： A method of treating or preventing an immune mediated disorder in a mammal, said method comprising the administration of a therapeutically effective amount of an estrogenic component to said mammal, wherein the estrogenic component is selected from the group consisting of: substances represented by the following formula: in which formula R1, R2, R3, R4 independently are a hydrogen atom, a hydroxyl group or an alkoxy group with 1-5 carbon atoms; each of R5, R6, R7 is a hydroxyl group; no more than 3 of R1, R2, R3, R4 are hydrogen atoms; precursors capable of liberating a substance according to the aforementioned formula when used in the present method; and mixtures of one or more of the aforementioned substances and/or precursors. Another aspect of the invention relates to a pharmaceutical formulation comprising the aforementioned estrogenic component, an immunotherapeutic agent and a pharmaceutically acceptable excipient.

    摘要翻译： 一种治疗或预​​防哺乳动物免疫介导的病症的方法，所述方法包括向所述哺乳动物施用治疗有效量的雌激素成分，其中雌激素成分选自：由下式表示的物质 式中R1，R2，R3，R4独立地为氢原子，羟基或具有1-5个碳原子的烷氧基; R5，R6，R7各自为羟基; 不超过3个R 1，R 2，R 3，R 4为氢原子; 在本方法中使用时能够释放根据上述式的物质的前体; 和一种或多种上述物质和/或前体的混合物。 本发明的另一方面涉及包含上述雌激素成分，免疫治疗剂和药学上可接受的赋形剂的药物制剂。

    Method of preparing and using isoflavones for the treatment of alcoholism
    8.
    发明授权
    Method of preparing and using isoflavones for the treatment of alcoholism 失效
    制备和使用异黄酮治疗酒精中毒的方法

    公开(公告)号：US06399072B1

    公开(公告)日：2002-06-04

    申请号：US09615152

    申请日：2000-07-13

    申请人： Mark Empie ,  Eric Gugger

    发明人： Mark Empie ,  Eric Gugger

    IPC分类号： A01N6500

    CPC分类号： C07D311/36 ,  A23L33/105 ,  A23L33/11 ,  A23V2002/00 ,  A61K36/185 ,  A61K36/48 ,  A61K36/488 ,  A61K36/55 ,  A61K36/68 ,  A61K36/82 ,  A61K36/899 ,  Y10S514/823 ,  Y10S514/824 ,  Y10S514/874 ,  Y10S514/899 ,  Y10S514/923 ,  A61K2300/00 ,  A23V2250/2116 ,  A23V2250/2132

    摘要： A composition is prepared by extracting phytochemicals from plant matter for treatment of alcohol dependency. This composition is enriched preferably with two or more fractions of plant matter, namely: isoflavones, lignans, saponins, sapogenins, catechins and phenolic acids. Soy is the preferred source of these chemicals; however, other plants may also be used, such as wheat, psyllium, rice, oats, red clover, kudzu, alfalfa, flax, and cocoa. The composition is a dietary supplement for treatment of alcoholism. The isoflavone may be any in a group including malonyl, acetyl, glucoside, and aglycone. The composition is in a concentrated form to be delivered in an easy to consume dosage, such as a pill, tablet, liquid, capsule, or a food supplement including a health bars.

    摘要翻译： 通过从植物物质中提取植物化学物质来处理酒精依赖性来制备组合物。 该组合物优选富含植物物质的两个或更多个部分，即异黄酮，木脂素，皂角苷，皂草苷，儿茶素和酚酸。 大豆是这些化学品的首选来源; 然而，也可以使用其它植物，例如小麦，欧车前，大米，燕麦，红三叶草，葛，苜蓿，亚麻和可可。 该组合物是用于治疗酒精中毒的膳食补充剂。 异黄酮可以是包括丙二酰基，乙酰基，葡糖苷和糖苷配基在内的任何一种。 组合物为浓缩形式，以易于消耗的剂量递送，例如丸剂，片剂，液体，胶囊或包括健康酒吧的食品补充剂。

    Transdermal application of naturally occurring steroid hormones
    9.
    发明授权
    Transdermal application of naturally occurring steroid hormones 失效
    透皮应用天然存在的类固醇激素

    公开(公告)号：US06228852B1

    公开(公告)日：2001-05-08

    申请号：US08889529

    申请日：1997-07-08

    申请人： Carolyn V. Shaak

    发明人： Carolyn V. Shaak

    IPC分类号： A61K3156

    CPC分类号： A61K31/565 ,  A61K31/57 ,  Y10S514/874 ,  Y10S514/937 ,  A61K2300/00

    摘要： The invention features a physiologically acceptable cream that contains estrogen, progesterone, and testosterone molecules that are identical to the estrogen, progesterone, and testosterone molecules naturally produced by the human body. The cream may be self-administered to the skin and is useful as a means of hormone replacement therapy, which may begin at around the time of menopause.

    摘要翻译： 本发明的特征在于生理上可接受的乳膏，其含有与人体天然产生的雌激素，孕酮和睾丸激素分子相同的雌激素，孕激素和睾酮分子。 该霜可以自身施用于皮肤，并且可用作激素替代疗法的手段，其可以在绝经期开始。