Method of producing low molecular weight chitin/chitosan and method of producing an osteoconduction substance
    1.
    发明授权
    Method of producing low molecular weight chitin/chitosan and method of producing an osteoconduction substance 失效
    生产低分子量壳多糖/壳聚糖的方法及生产骨传导物质的方法

    公开(公告)号:US07140882B2

    公开(公告)日:2006-11-28

    申请号:US10277928

    申请日:2002-10-23

    申请人: Michio Ito

    发明人: Michio Ito

    IPC分类号: A61K31/722 A61K2/28 A61K5/09

    摘要: By irradiating 60Co γ ray to chitin/chitosan, chitin/chitosan having high molecular weight is separated or decomposed into low molecular weight chitin/chitosan. A method of producing an osteoconduction substance comprises the steps of irradiating 60Co γ ray to chitin/chitosan to produce low molecular weight chitin/chitosan; preparing chitosan sol by dissolving low molecular weight chitin/chitosan in an acidic aqueous solution to obtain a chitosan acidic aqueous solution and kneading the chitosan acidic aqueous solution and apatite powder; and neutralizing the chitosan sol by the use of a neutralizing agent.

    摘要翻译: 通过向几丁质/壳聚糖照射60℃的Coγ射线,将具有高分子量的几丁质/壳聚糖分离或分解成低分子量几丁质/壳聚糖。 一种生产骨传导物质的方法包括以下步骤:向几丁质/壳聚糖照射60μMCoγ射线以产生低分子量几丁质/壳聚糖; 通过将低分子量几丁质/壳聚糖溶解在酸性水溶液中制备壳聚糖溶胶,得到壳聚糖酸性水溶液,并捏合壳聚糖酸性水溶液和磷灰石粉末; 并通过使用中和剂中和壳聚糖溶胶。

    Surface treated metallic implant and blasting material
    2.
    发明授权
    Surface treated metallic implant and blasting material 失效
    表面处理金属植入物和爆破材料

    公开(公告)号:US07377943B2

    公开(公告)日:2008-05-27

    申请号:US10480918

    申请日:2002-06-14

    摘要: The invention relates to a metallic implant, which has vitreous-crystalline bioactive material on the surface thereof. According to the invention, a metallic implant base body arranged on the surface of the particles has a bioactive, vitreous-crystalline material consisting of 15-45 wt. % CaO, 40-45 wt. % P2O5, 10-40 wt. % ZrO2 and 0.7-3.5 wt. % fluoride, having apatite and calcium zirconium phosphate as main crystalline and a glass phase as an auxiliary component. Said vitreous crystalline material contains at least 35 wt. % main crystal phases and at least 5-15 wt. % auxiliary compounds. All of the percentage data is expressed in relation to the total weight of the vitreous crystalline material and the particle size of the vitreous crystalline material is between 60-350 μm.

    摘要翻译: 本发明涉及一种在其表面上具有玻璃态生物活性物质的金属植入物。 根据本发明,布置在颗粒表面上的金属植入物基体具有生物活性的玻璃状结晶材料,其由15-45wt。 %CaO,40-45wt。 %P 2 O 5,10-40重量% %ZrO 2和0.7-3.5wt。 %氟化物,磷灰石和磷酸钙锆为主晶,玻璃相为辅助成分。 所述玻璃态结晶材料含有至少35wt。 %主晶相和至少5-15wt。 %辅助化合物。 所有百分比数据都以玻璃态结晶材料的总重量表示,玻璃状结晶材料的粒径在60-350μm之间。