公开(公告)号：US06322847B1

公开(公告)日：2001-11-27

申请号：US09685641

申请日：2000-10-10

Applicant: Sheng-ping Zhong ,  Vladimir B. Tsukernik

Inventor： Sheng-ping Zhong ,  Vladimir B. Tsukernik

IPC: A61L3300

CPC classification number: B05D3/042 ,  A61F2/01 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2220/0016 ,  A61F2230/0006 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/606 ,  B05C11/06 ,  C08L75/04 ,  C08L71/02 ,  C08L67/04

Abstract: Devices and methods for applying a polymeric coating to a medical device. The steps of the coating process including applying a liquid polymeric material to the surface of the medical device, then directing a stream of gas to impinge on the surface of the medical device. Excess liquid polymeric material is removed from the surface of the medical device. The devices used in the coating process and the coated medical device are also part of this invention.

Abstract translation: 将聚合物涂层施加到医疗装置的装置和方法。 涂覆工艺的步骤包括将液体聚合物材料施加到医疗装置的表面，然后引导气流冲击在医疗装置的表面上。 从医疗装置的表面除去过量的液体聚合材料。 在涂覆工艺中使用的装置和涂覆的医疗装置也是本发明的一部分。

公开(公告)号：US06443942B1

公开(公告)日：2002-09-03

申请号：US09876569

申请日：2001-06-06

Applicant: William Peter Van Antwerp ,  Poonam S. Gulati ,  Gerald E. Adomian

Inventor： William Peter Van Antwerp ,  Poonam S. Gulati ,  Gerald E. Adomian

IPC: A61L3300

Abstract: The present invention provides medical devices such as medication infusion pumps having internal surfaces that are treated to inhibit protein denaturation. In accordance with the invention, hydrophilic internal surfaces and related coating methods are provided to reduce or eliminate accumulation of medication deposits which can otherwise occur when handling complex protein-based medications. Preferred hydrophilic pump surfaces include hydrophilic surfactants (PEO) or (PEG) coatings which exhibit very low protein adsorption characteristics. Several methods are disclosed for producing such treated surfaces including the covalent attachment of hydrophilic surfactants.

公开(公告)号：US06551267B1

公开(公告)日：2003-04-22

申请号：US09691423

申请日：2000-10-18

Applicant: Richmond R. Cohen ,  Preston Keusch

Inventor： Richmond R. Cohen ,  Preston Keusch

IPC: A61L3300

CPC classification number: B01L3/5082 ,  A61B5/15003 ,  A61B5/150351 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/150755 ,  A61L33/0064 ,  A61L33/064 ,  C08L39/06

Abstract: A plastic medical article, such as a catheter or blood collection tube, is coated with a crosslinked hydrogel permanently bound to the inside wall of the tube. The hydrophilic surface provided by the hydrogel prevents adherence of blood components to the surface, and the permanent adherence of the hydrogel prevents its removal by blood.

Abstract translation: 诸如导管或采血管的塑料医疗制品涂覆有永久地结合到管的内壁的交联水凝胶。 由水凝胶提供的亲水表面防止血液成分粘附到表面，并且水凝胶的永久粘附防止其被血液除去。