公开(公告)号：US20040097758A1

公开(公告)日：2004-05-20

申请号：US10632103

申请日：2003-08-01

申请人： Solvay Fluor und Derivate GmbH

发明人： Max Braun ,  Carsten Brosch

IPC分类号： C07C057/64 ,  C07C017/08

CPC分类号： C01B17/4561 ,  C01B17/4576 ,  C07B39/00 ,  C07C17/206 ,  C07C67/307 ,  C07C69/63

摘要： Inorganic and organic compounds containing fluorine can be produced, for example, from corresponding chlorine-containing compounds by chlorine/fluorine exchange using fluorinating agents. Monocyclic or bicyclic compounds containing at least two nitrogen atoms, at least one of which is incorporated into the ring system, can be used as catalysts or fluorinating agents for chlorine/fluorine exchange reactions to produce sulfurylchlorofluoride, sulfurylfluoride or a carboxylic acid fluoride. It is likewise possible to carry out HF addition to unsaturated carbon-carbon bonds or chlorine/fluorine exchange at carbon atoms. For example, monochloro or dichloro malonic acid esters can be converted to difluoro malonic acid esters. Work-up of the reaction mixture can be simplified by using suitable solvents which force the reaction mixture to exist in two phases.

摘要翻译： 含氟的无机和有机化合物可以例如通过使用氟化剂的氯/氟交换从相应的含氯化合物制备。 含有至少两个氮原子（其中至少一个被引入环系中）的单环或双环化合物可用作氯/氟交换反应的催化剂或氟化剂，以产生磺酰氟氟化物，磺酰氟或羧酸氟化物。 同样可以在碳原子处进行HF添加到不饱和碳 - 碳键或氯/氟交换。 例如，一氯或二氯丙二酸酯可以转化为二氟丙二酸酯。 反应混合物的后处理可以通过使用强制反应混合物在两相中存在的合适的溶剂来简化。

公开(公告)号：US20040158100A1

公开(公告)日：2004-08-12

申请号：US10477198

申请日：2003-11-17

发明人： Masaki Irie ,  Masahiro Kondou

IPC分类号： C07C057/64

CPC分类号： C07C51/64 ,  C01B7/0706 ,  C01B7/093 ,  C01B7/195 ,  C01B32/80

摘要： The present invention provides a process for selectively separating HF and like acids present along with water-unstable organic acid fluorides. In particular, the invention provides a process for separating an acid from a system in which the acid and an organic acid fluoride are present, the organic acid fluoride being represented by formula (I): RCOFnullnull(I) wherein R is a fluorine atom; a C1-20 linear, branched or cyclic alkyl or halogenated alkyl group that may contain a heteroatom; or a C6-20 aryl or halogenated aryl group that may contain a heteroatom; the process comprising using as a deacidifying agent an aromatic heterocyclic compound having a boiling point of at least 50null C. and having one or more nitrogen atoms as heteroatom.

摘要翻译： 本发明提供了选择性分离与水不稳定的有机酸氟化物一起存在的HF等酸的方法。 特别地，本发明提供了从存在酸和有机氟化物的体系中分离酸的方法，有机酸氟化物由式（I）表示：RCOF（I）其中R是氟原子; 可以含有杂原子的C 1-20直链，支链或环状烷基或卤代烷基; 或可含有杂原子的C6-20芳基或卤代芳基; 该方法包括使用沸点为至少50℃并具有一个或多个氮原子作为杂原子的芳族杂环化合物作为脱酸剂。

公开(公告)号：US20040110968A1

公开(公告)日：2004-06-10

申请号：US10727610

申请日：2003-12-05

申请人： ASAHI GLASS COMPANY LIMITED

发明人： Takashi Okazoe ,  Kunio Watanabe ,  Masahiro Ito ,  Daisuke Shirakawa ,  Shin Tatematsu

IPC分类号： C07C057/64

CPC分类号： C08F24/00 ,  C07C41/48 ,  C07C51/58 ,  C07D317/42 ,  C08F16/24 ,  C07C59/135 ,  C07C43/313

摘要： The present invention provides novel processes for preparing a fluorinated acyl fluoride and a fluorinated vinyl ether. Namely, it provides a process for preparing a fluorinated acyl fluoride (3), which comprises reacting a compound (1) having a fluorine content of 30 mass % or above with fluorine in a liquid phase to form a compound (2) and then dissociating the ester bond in the compound (2), and a process for preparing a fluorinated vinyl ether (10), which comprises pyrolyzing the fluorinated acyl fluoride: 1 wherein RA and RB are alkyl groups or the like, or the combination RA and RB is an ethereal oxygen-containing alkylene group or the like, RC and RD are perfluoro(ethereal oxygen-containing alkyl) groups or the like, or the combination of RC and RD is a perfluoro(ethereal oxygen-containing alkylene) group or the like, X1, X2 X3, X4, X5 and X6 are hydrogen atoms, fluorine atoms or the like, RAF, RBF, RCF and RDF are groups derived respectively from RA, RB, RC and RD by replacing substantially all of the hydrogen atoms by fluorine atoms.

摘要翻译： 本发明提供了制备氟化酰氟和氟化乙烯基醚的新方法。 即，提供一种制备氟化酰基氟（3）的方法，其包括使氟含量为30质量％以上的化合物（1）与氟在液相中反应以形成化合物（2），然后解离 化合物（2）中的酯键和制备氟化乙烯基醚（10）的方法，其包括热解氟化酰基氟化物：其中R A和R B是烷基等，或 R A和R B的组合是含醚的亚烷基等，R C和R D均为全氟（醚性含氧烷基）基团等，或者R C 1和R D是全氟（醚性含氧亚烷基）基团等，X 1，X 2 X 3，X 4，X 5和X 6 >是氢原子，氟原子等，R“，R”，R“CF”和“R”是分别衍生自R a，R B，R C和 通过用氟原子代替基本上所有的氢原子。

公开(公告)号：US20030144546A1

公开(公告)日：2003-07-31

申请号：US10182260

申请日：2002-09-25

发明人： Susumu Amano ,  Masaru Mitsuda ,  Kenji Inoue ,  Koichi Kinoshita ,  Koki Yamashita ,  Yasuyoshi Ueda

IPC分类号： C07C323/22 ,  C07C057/72 ,  C07C057/64 ,  C07C059/01 ,  C07C059/11

CPC分类号： C07C327/32 ,  C07C51/04 ,  C07C51/367 ,  C07C51/60 ,  C07C59/48 ,  C07C57/58 ,  C07C57/76

摘要： A nitrous acid salt is added at a temperature of 10 to 80null C. to an aqueous solution which contains an optically active 2-aminocarboxylic acid (4) and a protonic acid, the amount of the latter acid being 1 to 3 equivalents to the former, and which has a proton concentration of 0.5 to 2 mol/kg to conduct a reaction to thereby produce an optically active 2-hydroxycarboxylic acid (1). Thionyl chloride and a basic compound are caused to act on the compound (1) to chlorinate it and simultaneously invert the configuration in the 2-position. Thus, an optically active 2-chlorocarboxylic acid chloride (5) is induced. The compound (5) is hydrolyzed to induce an optically active 2-chlorocarboxylic acid (2). The compound (2) is reacted with a thioacetic acid salt to incorporate an acetylthio group thereinto and simultaneously invert the configuration in the 2-position to thereby produce an optically active 2-acetylthiocarboxylic acid (3). 1

摘要翻译： 在10〜80℃的温度下，向含有光学活性的2-氨基羧酸（4）和质子酸的水溶液中加入亚硝酸盐，后者酸的量相对于前者为1〜3当量 ，其质子浓度为0.5〜2mol / kg进行反应，由此制造光学活性的2-羟基羧酸（1）。 使亚硫酰氯和碱性化合物作用于化合物（1）以使其氯化，同时反转2-位的构型。 因此，引入光学活性的2-氯羧酰氯（5）。 将化合物（5）水解以诱导光学活性的2-氯羧酸（2）。 使化合物（2）与硫代乙酸盐反应以在其中并入乙酰硫基，同时反转2-位的构型，从而产生光学活性的2-乙酰基硫代羧酸（3）

公开(公告)号：US20040116742A1

公开(公告)日：2004-06-17

申请号：US10322254

申请日：2002-12-17

申请人： 3M Innovative Properties Company

发明人： Miguel Antonio Guerra

IPC分类号： C07C057/64 ,  C07C39/82

CPC分类号： C07C303/22 ,  C07C51/58 ,  Y02P20/582 ,  C07C59/135 ,  C07C59/315 ,  C07C309/82

摘要： A method is provided for reacting hexafluoropropylene oxide (HFPO) with a perfluoroacyl fluorides according to the formula XnullRfnullCOF (II) to selectively produce a monoaddition product according to the formula XnullRfnullCF2nullOnullCF(CF3)COF (I), wherein selectivity for the monoaddition product over the biaddition product is 90% or greater or more typically 95% or greater. A continuous or repeated-batch process is provided comprising the steps of: a) providing a mixture of XnullRfnullCOF (II), a fluoride salt, and a polar solvent; b) adding hexafluoropropylene oxide (HFPO) in an amount such that XnullRfnullCOF remains in molar excess of HFPO by at least 10% and reacting XnullRfnullCOF with HFPO; c) separating unreacted XnullRfnullCOF from a mixture of addition products of hexafluoropropylene oxide (HFPO) and XnullRfnullCOF; and d) repeating step a) using unreacted XnullRfnullCOF separated in step c).

摘要翻译： 提供了一种用于使六氟环氧丙烷（HFPO）与根据式X-Rf-COF（II）的全氟酰基氟化物反应的方法，以选择性地制备根据式X-Rf-CF2-O-CF（CF3）COF的单加成产物 （I），其中加成产物相对于加合产物的选择性为90％或更大或更通常为95％或更高。 提供连续或重复分批的方法，包括以下步骤：a）提供X-Rf-COF（II），氟化物盐和极性溶剂的混合物; b）加入六氟环氧丙烷（HFPO），其量使得X-Rf-COF保持摩尔过量的HFPO至少10％，并使X-Rf-COF与HFPO反应; c）从六氟环氧丙烷（HFPO）和X-Rf-COF的加成产物的混合物中分离未反应的X-Rf-COF; 和d）重复步骤a）使用在步骤c）中分离的未反应的X-Rf-COF。

公开(公告)号：US20040024249A1

公开(公告)日：2004-02-05

申请号：US10630697

申请日：2003-07-31

申请人： SOLVAY SOLEXIS S.p.A.

发明人： Rosaldo Picozzi ,  Antonella Di Meo ,  Claudio Tonelli

IPC分类号： C07C051/58 ,  C07C057/64 ,  C07C047/02

CPC分类号： C07C43/137 ,  C07C43/126 ,  C07C43/315 ,  C07C59/135 ,  C08G65/007 ,  C08G65/226 ,  C08G65/322

摘要： Hydrofluoroethers of formula:TnullCFXnullnullOnullRfnullCFXnullTnullnullnull(II)wherein: TnullCH3; X, Xnull, equal to or different from each other, are selected between F, CF3; T00nullnullF, Cl, H, C1-C3 perfluoroalkyl, CH3, CH2OH, COCl, CHO, CO2H; Rf is a perfluoroalkylene or a perfluoropolyoxyalkylene and respective preparation process by reduction with hydrogen in the presence of a platinum catalyst supported on metal fluorides of the corresponding compounds with at least one nullCOCl end group.

摘要翻译： 式：T-CFX'-O-Rf-CFX-T'（II）的氢氟醚其中：T = CH 3; X，X'彼此相等或不同，选自F，CF 3; T00'= F，Cl，H，C1-C3全氟烷基，CH3，CH2OH，COCl，CHO，CO2H; Rf是全氟亚烷基或全氟聚氧亚烷基，各自的制备方法是在负载在具有至少一个-COCl端基的相应化合物的金属氟化物上的铂催化剂存在下用氢还原。

公开(公告)号：US20010014759A1

公开(公告)日：2001-08-16

申请号：US09769797

申请日：2001-01-25

发明人： Albrecht Marhold ,  Jorn Stolting

IPC分类号： C07C051/58 ,  C07C053/38 ,  C07C055/36 ,  C07C057/64 ,  C07C059/00 ,  C07C061/00 ,  C07C062/00 ,  C07C063/00 ,  C07C065/00

CPC分类号： C07C51/60 ,  C07C51/62 ,  C07C63/70 ,  C07C63/72

摘要： 3,5-Bis(trifluoromethyl)benzoyl chlorides optionally substituted with fluorine or chlorine are advantageously prepared by converting 3,5-dimethylbenzoic acids optionally substituted with fluorine or chlorine into the corresponding acid chlorides; completely free-radically chlorinating said chlorides in the side chains, giving 3,5-bis(trichloromethyl)benzoyl chlorides optionally substituted by fluorine or chlorine; fluorinating the latter with anhydrous hydrogen fluoride and/or antimony pentafluoride, giving 3,5-bis(trifluoromethyl)benzoyl fluorides optionally substituted with fluorine or chlorine; and then reacting the 3,5-bis(trifluoromethyl)benzoyl fluorides with silicon tetrachloride in the presence of a further Lewis acid. Some of the 3,5-bis(trihalogenomethyl) and 3,5-dimethylbenzoyl halides which arise as intermediates are novel compounds.

摘要翻译： 任选被氟或氯取代的3,5-双（三氟甲基）苯甲酰氯有利地通过将任选被氟或氯取代的3,5-二甲基苯甲酸转化成相应的酰氯来制备; 完全自由基地氯化侧链中的氯化物，得到任选被氟或氯取代的3,5-双（三氯甲基）苯甲酰氯; 用无水氟化氢和/或五氟化锑氟化后者，得到任选被氟或氯取代的3,5-双（三氟甲基）苯甲酰氟; 然后在另外的路易斯酸的存在下使3,5-双（三氟甲基）苯甲酰氟与四氯化硅反应。 作为中间体产生的一些3,5-二（三卤代甲基）和3,5-二甲基苯甲酰基卤化物是新的化合物。