公开(公告)号：US06835571B2

公开(公告)日：2004-12-28

申请号：US10652398

申请日：2003-08-29

Applicant: Dennis R. Conlon ,  Minna A. Rannikko ,  Kevin J. Sullivan ,  Robert B. Green

Inventor： Dennis R. Conlon ,  Minna A. Rannikko ,  Kevin J. Sullivan ,  Robert B. Green

IPC: G01N3100

CPC classification number: B65D75/5877 ,  B01L3/505 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2300/10 ,  B32B15/08 ,  B65D75/58 ,  B65D75/5861 ,  G01N27/4163 ,  G01N33/0006 ,  G01N33/4925 ,  G01N33/96 ,  G01N2001/2893 ,  G01N2496/70 ,  G01N2496/80 ,  Y10T436/10 ,  Y10T436/100833 ,  Y10T436/102499 ,  Y10T436/104998 ,  Y10T436/105831 ,  Y10T436/106664 ,  Y10T436/25

Abstract: Multi-analyte reference solutions having a stable partial pressure of oxygen (pO2) in zero headspace packaging and methods for preparing such solutions are disclosed. The solutions have long shelf and use lives when stored at room temperature and are packaged in laminated foil containers having low or no oxygen reactivity. Access devices are also disclosed.

Abstract translation: 公开了在零顶空包装中具有稳定的氧分压（pO2）和制备这种溶液的方法的多分析物参比溶液。 当在室温下储存时，溶液具有长的搁置和使用寿命，并且被包装在具有低或不具有氧反应性的层压箔容器中。 还公开了接入设备。

公开(公告)号：US06811751B1

公开(公告)日：2004-11-02

申请号：US09297798

申请日：2002-04-11

Applicant: Sven Gunnar Olsson ,  Stefan Brauer ,  Anders Linge ,  Tarmo Niininen ,  Krista Nilsson ,  Goran Rydgren

Inventor： Sven Gunnar Olsson ,  Stefan Brauer ,  Anders Linge ,  Tarmo Niininen ,  Krista Nilsson ,  Goran Rydgren

IPC: G01N3100

CPC classification number: G01N21/3504 ,  G01N21/85 ,  G01N33/4972 ,  G01N2021/151 ,  G01N2021/158 ,  G01N2021/3174 ,  Y10T436/20 ,  Y10T436/204165 ,  Y10T436/204998

Abstract: Method and apparatus for determining in a person's exhalation air the concentration of a specific substance in the blood by measuring the concentration of said substance and the concentration of water vapor in the exhalation air and utilizing a known relationship between these concentrations. When the method is applied the exhalation air is exhaled freely in a defined air volume having a predetermined composition, and said concentrations are measured in this air volume. The apparatus for working the method comprises a device (16) which defines a space for receiving the exhalation air, which has two mutually opposite openings through which the space communicates with the surrounding air, and means (18, 22, 23) for selective quantitative detection of said substance in the air in the defined space.

公开(公告)号：US06807492B2

公开(公告)日：2004-10-19

申请号：US09900491

申请日：2001-07-09

Applicant: Avraham Oren ,  Yehuda Hartman ,  Yossi Fisher

Inventor： Avraham Oren ,  Yehuda Hartman ,  Yossi Fisher

IPC: G01N3100

CPC classification number: G06Q30/06 ,  G06Q30/0629

Abstract: An automated modeler for modeling of an interactive system comprising at least one biological entity and at least one pharmaceutical substance, the system comprising, a representation of states of said system, a knowledge tree builder, associated with said representation for allowing users to define the states, expected relationships between said states and independent inputs to the states, and a data miner associated with said representation to operate on data taken from said system to apply said data to said states in accordance with said defined relationships and inputs, thereby to apply numerical values to said relationships and said inputs, thereby to model said interactions.

Abstract translation: 一种用于对包括至少一个生物实体和至少一种药物物质的交互式系统进行建模的自动建模器，所述系统包括与所述表示相关联的所述系统的状态的表示，以允许用户定义状态 所述状态和状态的独立输入之间的预期关系以及与所述表示相关联的数据挖掘机，以对从所述系统取得的数据进行操作，以根据所述定义的关系和输入将所述数据应用于所述状态，由此应用数值 对所述关系和所述输入，从而对所述交互进行建模。

公开(公告)号：US06804610B2

公开(公告)日：2004-10-12

申请号：US10401206

申请日：2003-03-27

Applicant: Thomas B. Morrow ,  Kendricks A. Behring, II

Inventor： Thomas B. Morrow ,  Kendricks A. Behring, II

IPC: G01N3100

CPC classification number: G01N29/024 ,  G01N33/225 ,  G01N2291/0215 ,  G01N2291/02809 ,  G01N2291/02818 ,  G01N2291/02836 ,  G01N2291/02881

Abstract: A methods of indirectly measuring the nitrogen concentration in a gas mixture. The molecular weight of the gas is modeled as a function of the speed of sound in the gas, the diluent concentrations in the gas, and constant values, resulting in a model equation. Regression analysis is used to calculate the constant values, which can then be substituted into the model equation. If the speed of sound in the gas is measured at two states and diluent concentrations other than nitrogen (typically carbon dioxide) are known, two equations for molecular weight can be equated and solved for the nitrogen concentration in the gas mixture.

Abstract translation: 间接测量气体混合物中氮浓度的方法。 气体的分子量被模拟为气体中的声速，气体中的稀释剂浓度和常数值的函数，导致模型方程式。 回归分析用于计算常数值，然后将其代入模型方程。 如果在两种状态下测量气体中的声速，并且已知氮气（通常为二氧化碳）以外的稀释剂浓度，则可以将气体混合物中的氮浓度的两个分子式等式和解决。

公开(公告)号：US06803235B1

公开(公告)日：2004-10-12

申请号：US09595583

申请日：2000-06-15

Applicant: John D. Mize ,  Russell B. Gore ,  Ronald H. Fleming

Inventor： John D. Mize ,  Russell B. Gore ,  Ronald H. Fleming

IPC: G01N3100

CPC classification number: G01N31/02 ,  G01N33/20 ,  Y10T436/112499 ,  Y10T436/23

Abstract: The invention encompasses a method of generating information about materials in a composition. A reagent is utilized to dissolve portions of the composition, and thereafter is filtered through a substrate which is then scanned with a microscope using automated displacement of the substrate to obtain data about the non-dissolved portions at locations along a grid pattern. Information about the size and quantity of the non-dissolved portions of the composition is generated. The invention also encompasses a method of generating information about impurities present in a metal composition. Metallic portions of the composition are selectively dissolved relative to impurities to form a solution. The solution is filtered through a substrate which is then scanned with a microscope to obtain data about a darkness of the impurities relative to a background. The data is processed to generate information about the size, quantity and type of the impurities.

Abstract translation: 本发明包括生成关于组合物中的材料的信息的方法。 使用试剂来溶解组合物的部分，然后通过基材过滤，然后用显微镜使用基板的自动置换扫描，以获得关于沿着网格图案的位置处的未溶解部分的数据。 产生关于组合物的未溶解部分的大小和数量的信息。 本发明还包括产生关于存在于金属组合物中的杂质的信息的方法。 组合物的金属部分相对于杂质选择性溶解以形成溶液。 将溶液通过底物过滤，然后用显微镜扫描以获得关于杂质相对于背景的黑暗的数据。 处理数据以产生关于杂质的大小，数量和类型的信息。

公开(公告)号：US06785615B2

公开(公告)日：2004-08-31

申请号：US10284510

申请日：2002-10-29

Applicant: Michael Edward Scaman

Inventor： Michael Edward Scaman

IPC: G01N3100

CPC classification number: H01J37/3045

Abstract: An apparatus and method for detection of electromechanical and mechanical errors in an electron beam device is provided. First the existing subfield is divided into a gridlike structure where each grid can be considered a target. Then a plurality of target points are provided on each grid for measuring combined directional variances. The separated horizontal and vertical variances is also measured for each of the target points. This leads to the performance of a significance tests, based on the F statistic which we refer to as FHV, for horizontal and vertical values of each target points during which FSTITCH values are also obtained. The FSTITCH values are then compared for horizontal and vertical values and an error alert provided when there is a sufficiently large disparity between the separated FSTITCH values. In an alternate embodiment of the present invention, a three dimensional grid is also provided to be used in a similar manner. The severity of the error can also be determined based on the disparity of the values. Lastly we refer to a simple F statistic for testing for flatness of the entire field, based on row and field information and refer to it as FROWS.

公开(公告)号：US06782323B2

公开(公告)日：2004-08-24

申请号：US10133539

申请日：2002-04-25

Applicant: Takayuki Kotani

Inventor： Takayuki Kotani

IPC: G01N3100

CPC classification number: G06F19/705

Abstract: A molecular similarity evaluation method has steps of: (a) obtaining an upper threshold and a lower threshold from one of a value specific to an atom included in a first molecule, a value specific to an atom included in a second molecule of which correlation with respect to the atom in the first molecule is to be evaluated, or another value obtained from these values; (b) calculating the correlation between the atom in the first molecule and the atom in the second molecule, using the upper and lower thresholds; and (c) evaluating the similarity between the first and second molecules based on the correlation obtained in the step (b).

Abstract translation: 分子相似性评价方法具有以下步骤：（a）从包含在第一分子中的原子的特定值的值中获得上限阈值和下限阈值，对与第一分子相关的第二分子中包含的原子的特异性值 要评估第一分子中的原子，或从这些值获得的另一个值; （b）使用上限和下限计算第一分子中的原子与第二分子中的原子之间的相关性; 和（c）基于步骤（b）中获得的相关性来评估第一和第二分子之间的相似性。

公开(公告)号：US06762017B2

公开(公告)日：2004-07-13

申请号：US10053946

申请日：2002-01-24

Applicant: Richard Torres ,  Robert A. Levine ,  Stephen C. Wardlaw

Inventor： Richard Torres ,  Robert A. Levine ,  Stephen C. Wardlaw

IPC: G01N3100

CPC classification number: G01N33/96 ,  Y10T436/10 ,  Y10T436/106664

Abstract: A non-animal based mixture of components serves as a control for complete blood count (CBC) analysis instruments and paraphernalia. The centrifugible non-animal based mixture simulates blood, and contains blood cell-simulating and other blood constituent-simulating components which are present in the mixture in controlled and known amounts. The mixture can be gravimetrically separated into its blood constituent-simulating components so as to serve as a control that simulates a centrifuged blood sample, and is thus used to check the accuracy of CBC blood analysis instruments, such as those marketed by Becton Dickinson and Company, under the trademark “QBC”.

Abstract translation: 基于非动物的组分混合物用作完全血细胞计数（CBC）分析仪器和用具的对照。 离心非基于动物的混合物模拟血液，并含有以受控和已知量存在于混合物中的血细胞模拟和其他血液成分模拟组分。 混合物可以重力分离成其血液成分模拟组分，以作为模拟离心血液样品的对照，因此用于检查CBC血液分析仪器的准确性，如Becton Dickinson和Company ，商标为“QBC”。

公开(公告)号：US06756230B2

公开(公告)日：2004-06-29

申请号：US09858986

申请日：2001-05-16

Applicant: Yuichiro Noda ,  Yoshiyuki Tanaka ,  Konomu Hirao

Inventor： Yuichiro Noda ,  Yoshiyuki Tanaka ,  Konomu Hirao

IPC: G01N3100

CPC classification number: G01N33/96 ,  Y10T436/10 ,  Y10T436/193333 ,  Y10T436/25 ,  Y10T436/255

Abstract: Amounts of components in a specimen can be analyzed with excellent quantitativity. The analysis includes: measuring an amount of a component to be analyzed in a specimen; measuring an amount of a standard component present originally and homeostatically in the specimen other than the component to be analyzed; determining the amount of the specimen from the amount of the standard component thus measured and a known concentration of the standard component in the specimen; and determining a concentration of the component to be analyzed in the specimen from the amount of the specimen thus determined and the amount of the component to be analyzed thus measured. The quantitative analysis of the present invention allows a component to be analyzed to be measured with high quantitativity as shown in FIG. 1.

Abstract translation: 可以以极好的定量分析样品中组分的量。 分析包括：测量样品中要分析的组分的量; 测量除了要分析的组分之外的样品中最初和稳定存在的标准组分的量; 从所测量的标准组分的量和样品中标准组分的已知浓度确定样品的量; 以及根据如此测定的试样的量和待测量的成分的量来测定试样中要分析的成分的浓度。 本发明的定量分析允许如图1所示以高定量度量测分析成分。 1。

公开(公告)号：US06745132B1

公开(公告)日：2004-06-01

申请号：US10219684

申请日：2002-08-15

Applicant: Touradj Solouki ,  Alireza Fattahi

Inventor： Touradj Solouki ,  Alireza Fattahi

IPC: G01N3100

CPC classification number: G01N27/4166 ,  Y10T436/156666

Abstract: A systematic treatment of chemical equilibria is used to determine the average molecular weight of the Suwannee River fulvic acids directly from aqueous solutions. Additionally, parameters such as equilibrium constant and reaction stoichiometry can be calculated. The measurement of the initial mass of unknown analytes is not needed for the determination.

Abstract translation: 使用化学平衡的系统处理直接从水溶液中测定Suwannee River富里酸的平均分子量。 此外，可以计算诸如平衡常数和反应化学计量的参数。 不需要测量未知分析物的初始质量。