公开(公告)号：US06835570B2

公开(公告)日：2004-12-28

申请号：US10712679

申请日：2003-11-12

申请人： Harshad Patel

发明人： Harshad Patel

IPC分类号： G01N3100

CPC分类号： G01N33/558 ,  Y10T436/10 ,  Y10T436/2575

摘要： In connection with a fluidic medical diagnostic device that permits measurement of the coagulation time of blood, software, methods and associated devices for quality control are provided. The fluidic device preferably includes a test strip with one end having a sample port for introducing a sample and a bladder at the other end for drawing the sample to a measurement area. A channel carries sample from the sample port to an assay measurement area and first and second control measurement areas. Preferably a stop junction, between the measurement areas and bladder, halts the sample flow for measurement. If results from measurements taken for each control fall within a predetermined zone or defined limits, the assay measurement is qualified. If not, an error is registered and the test strip is counted as unfit.

摘要翻译： 关于允许测量血液凝固时间的流体医疗诊断装置，提供了用于质量控制的软件，方法和相关装置。 流体装置优选地包括测试条，其一端具有用于引入样品的样品端口和另一端的气囊，用于将样品拉伸到测量区域。 通道将样品从样品端口运送到测定测量区域以及第一和第二控制测量区域。 优选地，在测量区域和气囊之间的停止接头停止用于测量的样品流。 如果每个对照的测量结果落在预定区域或限定的限度内，则测定测定是合格的。 如果没有，则会注册错误，并将测试条计为不合格。

公开(公告)号：US06823238B1

公开(公告)日：2004-11-23

申请号：US09579702

申请日：2000-05-26

申请人： Gary L. Hensley ,  Lee Hilpert

发明人： Gary L. Hensley ,  Lee Hilpert

IPC分类号： G01N3100

CPC分类号： E21B21/06

摘要： A method and apparatus selective remove undesirable low gravity components from the return stream of drilling mud. The apparatus receives mud returned from the well borehole and transfers the mud to a tank. Mud from the tank is treated in a separation system including a plurality of mass flow sensor to monitor operation of the system.

摘要翻译： 选择性地从钻井泥浆回流中去除不需要的低重力组分的方法和装置。 该装置接收从井眼返回的泥浆并将泥浆转移到罐中。 来自罐的泥浆在包括多个质量流量传感器的分离系统中被处理以监测系统的操作。

公开(公告)号：US06820013B1

公开(公告)日：2004-11-16

申请号：US10168578

申请日：2002-10-16

申请人： Hans Frickel ,  Hanshelmut Itzel ,  Joachim Born

发明人： Hans Frickel ,  Hanshelmut Itzel ,  Joachim Born

IPC分类号： G01N3100

CPC分类号： G01N21/31

摘要： The invention relates to a method and an apparatus for the on-line analysis of liquid substance mixtures by means of NIRS. For evaluation by spectral data comparison, merely the binary mixtures of the possible components in quantitative graduations are used as calibration spectra. In order to accelerate the evaluation, all data points of a spectrum are summated, and each spectrum is characterized by only one characteristic number.

摘要翻译： 本发明涉及一种通过NIRS在线分析液体物质混合物的方法和装置。 为了通过光谱数据比较进行评估，仅将定量刻度中可能的组分的二元混合物用作校准光谱。 为了加速评估，对频谱的所有数据点进行求和，每个频谱的特征仅在于一个特征数。

公开(公告)号：US06816793B2

公开(公告)日：2004-11-09

申请号：US10311563

申请日：2002-12-16

申请人： Kwok Yui Chow ,  Danielle Marie Lockhart ,  Andrew Giuseppi Guido Tallevi

发明人： Kwok Yui Chow ,  Danielle Marie Lockhart ,  Andrew Giuseppi Guido Tallevi

IPC分类号： G01N3100

CPC分类号： G06Q10/06 ,  G01F1/00 ,  G01F1/74 ,  G01F25/00 ,  G01N11/00 ,  G01N11/02 ,  G01N33/15 ,  G01N2033/0091 ,  G01N2203/0284

摘要： A method for predicting flow properties of one or more materials proposed for processing in a system that requires good flow properties to operate successfully includes identifying a plurality of key flow points along a system, for each key flow point so identified, characterizing the type of flow occurring at that key flow point, for each key flow point, selecting a flow test relevant for modeling the type of flow occurring at that key flow point, providing a plurality of material samples wherein each material sample has a different composition, blend and/or concentration of ingredients, for each key flow point, modeling the type of flow occuring at that key flow point by conducting the flow test selected for that key flow point on each material sample to produce a plurality of test result values, wherein each test result value is a function of one of the flow tests conducted and of the material sample tested by that flow test, and ranking each material sample based on a calculated average of the test result values to determine which of the material samples tested has optimal overall flow properties for the system as compared against the other material samples.

摘要翻译： 一种用于预测在系统中进行处理的一种或多种材料的流动性质的方法，该方法需要良好的流动性能以便成功地运行，包括为所识别的每个关键流动点识别多个沿着系统的关键流动点，表征流动类型 发生在该关键流动点处，对于每个关键流动点，选择与在该关键流动点处发生的流动类型建模相关的流动测试，提供多个材料样品，其中每个材料样品具有不同的组成，混合和/或 成分浓度，对于每个关键流动点，通过对每个材料样品上的该关键流程点进行流动测试，对在该关键流动点发生的流动类型建模，以产生多个测试结果值，其中每个测试结果值 是进行的流程测试之一和通过该流程测试测试的材料样品的函数，并且基于所计算的av 测试结果值的磨损，以确定与其他材料样品相比，所测试的材料样品中的哪一个与系统具有最佳的总体流动性能。

公开(公告)号：US06787361B1

公开(公告)日：2004-09-07

申请号：US09853867

申请日：2001-05-11

申请人： George G. Klee

发明人： George G. Klee

IPC分类号： G01N3100

CPC分类号： G01N33/50 ,  Y10T436/10 ,  Y10T436/11

摘要： A method for calibrating a clinical laboratory analytical instrument that includes generating control pool data from a commutable control pool, wherein the control pools have target analyte values for an assay, generating patient specimen data from a distribution of test values from patient specimens, determining tolerance limits from the control pool data and the patient specimen data; and adjusting the calibration of the instrument with respect to the tolerance limits.

摘要翻译： 一种用于校准临床实验室分析仪器的方法，包括从可换向对照池产生控制池数据，其中所述对照池具有用于测定的目标分析物值，从来自患者标本的测试值的分布产生患者样本数据，确定耐受极限 从控制池数据和患者标本数据; 并相对于公差极限调整仪器的校准。

公开(公告)号：US06777240B2

公开(公告)日：2004-08-17

申请号：US10241344

申请日：2002-09-11

申请人： Kevin H. Hazen ,  James Matthew Welch ,  Stephen F. Malin ,  Timothy L. Ruchti ,  Alexander D. Lorenz ,  Tamara L. Troy ,  Suresh Thennadil ,  Thomas B. Blank

发明人： Kevin H. Hazen ,  James Matthew Welch ,  Stephen F. Malin ,  Timothy L. Ruchti ,  Alexander D. Lorenz ,  Tamara L. Troy ,  Suresh Thennadil ,  Thomas B. Blank

IPC分类号： G01N3100

CPC分类号： G01N21/274 ,  A61B5/0075 ,  A61B5/1075 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/1495 ,  A61B5/7264 ,  A61B2560/0223 ,  A61B2560/0233 ,  G01N21/359 ,  G01N21/4785 ,  G01N21/49 ,  Y10T436/10

摘要： The invention provides a class of samples that model the human body. This family of samples is based upon emulsions of oil in water with lecithin acting as the emulsifier. These solutions that have varying particle sizes may be spiked with basis set components (albumin, urea and glucose) to simulate skin tissues further. The family of samples is such that other organic compounds such as collagen, elastin, globulin and bilirubin may be added, as can salts such as Na+, K+and Cl−. Layers of varying thickness with known index of refraction and particle size distributions may be generated using simple crosslinking reagents, such as collagen (gelatin). The resulting samples are flexible in each analyte's concentration and match the skin layers of the body in terms of the samples reduced scattering and absorption coefficients, &mgr;'s and &mgr;a. This family of samples is provided for use in the medical field where lasers and spectroscopy based analyzers are used in treatment of the body. In particular, knowledge may be gained on net analyte signal, photon depth of penetration, photon radial diffusion, photon interaction between tissue layers, photon density (all as a function of frequency) and on instrument parameter specifications such as resolution and required dynamic range (A/D bits required). In particular, applications to delineate such parameters have been developed for the application of noninvasive glucose determination in the near-IR region from 700 to 2500 nm with an emphasis on the region 1000 to 2500 nm (10,000 to 4,000 cm−1).

摘要翻译： 本发明提供了一类对人体进行建模的样品。 该样品系基于水中的油与卵磷脂作为乳化剂的乳液。 具有不同粒径的这些溶液可以加入基础组分（白蛋白，尿素和葡萄糖）以进一步模拟皮肤组织。 样品家族可以加入其它有机化合物如胶原蛋白，弹性蛋白，球蛋白和胆红素，也可以加入诸如Na +，K +和Cl - 的盐。 可以使用简单的交联试剂如胶原（明胶）产生具有已知折射率和粒度分布的不同厚度的层。 所得样品在每种分析物的浓度上是柔性的，并且根据样品减少的散射和吸收系数mu和μa来匹配身体的皮肤层。 该样品系列用于医疗领域，其中使用激光和基于光谱的分析仪来治疗身体。 特别地，可以获得关于净分析物信号，光子穿透深度，光子径向扩散，组织层之间的光子相互作用，光子密度（全部作为频率的函数）以及仪器参数规格（例如分辨率和所需动态范围） 需要A / D位）。 特别地，已经开发出描绘这些参数的应用，用于在700至2500nm的近红外区域中应用非侵入性葡萄糖测定，重点在1000至2500nm（10,000至4000cm -1）的区域。

公开(公告)号：US06763309B2

公开(公告)日：2004-07-13

申请号：US10068244

申请日：2002-02-05

申请人： Laurent Kieken ,  Enrique Iglesia ,  Matthew Neurock ,  John Matthew Trenkle

发明人： Laurent Kieken ,  Enrique Iglesia ,  Matthew Neurock ,  John Matthew Trenkle

IPC分类号： G01N3100

CPC分类号： B01J19/0046 ,  B01J2219/00274 ,  B01J2219/00286 ,  B01J2219/00391 ,  B01J2219/00423 ,  B01J2219/00495 ,  B01J2219/00587 ,  B01J2219/00596 ,  B01J2219/007 ,  B01J2219/00745 ,  B01J2219/00747 ,  C40B30/02 ,  C40B30/08 ,  C40B40/18 ,  C40B50/02 ,  C40B60/14 ,  G06F19/706 ,  G06F19/707

摘要： A catalyst development engine (CDE) provides a rapid approach to the rational development of scalable heterogeneous catalysts and of high-performance solid materials. The CDE includes three main components: the testing cycle, the knowledge cycle, and the knowledge repository or database. The knowledge cycle generates working hypotheses relating performance to key catalyst properties via machine learning methods, computation chemistry and micro-kinetic modeling. Such an approach accelerates development and scale-up of new materials without the impediments introduced by conventional combinatorial approaches based on randomly selected materials.

摘要翻译： 催化剂开发引擎（CDE）为可扩展的非均相催化剂和高性能固体材料的合理开发提供了快速的方法。 CDE包括三个主要组成部分：测试周期，知识周期以及知识库或数据库。 知识循环通过机器学习方法，计算化学和微动力学建模产生了关键催化剂性能的工作假说。 这种方法加速了新材料的开发和扩大，而没有基于随机选择的材料的常规组合方法引入的障碍。

公开(公告)号：US06757619B2

公开(公告)日：2004-06-29

申请号：US10214947

申请日：2002-08-07

申请人： Stanley W. Zison ,  Joseph Bingham

发明人： Stanley W. Zison ,  Joseph Bingham

IPC分类号： G01N3100

CPC分类号： G01N33/0031 ,  G01D1/00 ,  G01N33/004 ,  G01N33/0042 ,  Y02A50/243 ,  Y02A50/248

摘要： In a data acquisition system and method for real time monitoring of stack gases in a continuous monitoring system, data is collected from sensors and prepared for output to a regulatory agency. The data collected may relate to emissions of oxides of nitrogen, carbon monoxide, and oxides of sulfur, typically from an industrial facility. Sensors in the exhaust gas pathway report data to a programmable logic control device and are then stored in a data storage area. A data acquisition module quantifies the stored emissions data. The quantified emissions data is then sent to a regulatory agency via a communications link.

摘要翻译： 在连续监测系统中实时监测烟气的数据采集系统和方法中，从传感器收集数据并准备输出到监管机构。 收集的数据可能与通常来自工业设施的氮氧化物，一氧化碳和硫的氧化物的排放有关。 废气通道中的传感器将数据报告给可编程逻辑控制装置，然后存储在数据存储区域中。 数据采集​​模块量化存储的排放数据。 量化的排放数据然后通过通信链路发送到监管机构。

公开(公告)号：US06706526B2

公开(公告)日：2004-03-16

申请号：US10056617

申请日：2002-01-24

申请人： Russell F. Lang ,  Iris L. Payan ,  Barbara G. Murza ,  Luisa C. Oramas

发明人： Russell F. Lang ,  Iris L. Payan ,  Barbara G. Murza ,  Luisa C. Oramas

IPC分类号： G01N3100

CPC分类号： G01N33/5094 ,  Y10T436/10 ,  Y10T436/101666 ,  Y10T436/108331 ,  Y10T436/202499 ,  Y10T436/2525

摘要： A low formaldehyde containing aqueous blood diluent contains an effective amount of ethylenediamine tetraacetic acid, ethylenediamine tetraacetic acid derivative, or combinations thereof; an effective amount of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one; and an effective amount of 5-bromo-5-nitro-1,3-dioxane. Advantageously, less than about 1 parts per million of formaldehyde is produced in this multipurpose diluent. A method of analyzing a blood sample containing blood cells is conducted by forming a diluted blood sample by mixing a blood sample containing blood cells with this diluent and analyzing the diluted blood sample to determine a physical parameter of the blood cells.

摘要翻译： 低含甲醛的含水稀释剂含有有效量的乙二胺四乙酸，乙二胺四乙酸衍生物或其组合; 有效量的5-氯-2-甲基-4-异噻唑啉-3-酮和2-甲基-4-异噻唑啉-3-酮; 和有效量的5-溴-5-硝基-1,3-二恶烷。 有利的是，在该多用途稀释剂中产生少于约1ppm的甲醛。 通过将含有血细胞的血液样品与该稀释剂混合并分析稀释的血液样品来确定血细胞的物理参数，通过形成稀释的血液样品来进行含有血细胞的血液样品的分析方法。

公开(公告)号：US06701255B2

公开(公告)日：2004-03-02

申请号：US09844282

申请日：2001-04-30

申请人： James P. Batug ,  Carlos E. Romero ,  Ali Yilmaz ,  Edward K. Levy ,  Noel Moyer

发明人： James P. Batug ,  Carlos E. Romero ,  Ali Yilmaz ,  Edward K. Levy ,  Noel Moyer

IPC分类号： G01N3100

CPC分类号： G01N1/2258 ,  G01N33/0018 ,  G01N33/0037 ,  G01N33/004 ,  G01N33/0042 ,  G01N2001/2264 ,  Y02A50/245

摘要： An emission measuring system and method provide an accurate, real-time calculation of a particular material emitted from an emission source. Specifically, a CEM system installed in an industrial stack can include a dilution probe located in the stack and a data analyzer that records and analyzes characteristic data of the materials sampled by the dilution probe. A dilution ratio is used to correct for the addition of dilution gas into the stack gas sample to determine the concentration of a particular material that is being emitted from the stack. The dilution ratio is based on a molar flow rate, which can be determined by using specific algorithms and measurements.

摘要翻译： 排放测量系统和方法提供从发射源发射的特定材料的精确的实时计算。 具体来说，安装在工业堆栈中的CEM系统可以包括位于堆叠中的稀释探针和用于记录和分析由稀释探针采样的材料的特征数据的数据分析器。 稀释比用于校正将稀释气体添加到堆叠气体样品中以确定从堆叠发射的特定材料的浓度。 稀释比基于摩尔流速，其可以通过使用特定算法和测量来确定。