METHOD FOR THE HYPERPOLARISATION OF NUCLEAR SPINS
    1.
    发明申请
    METHOD FOR THE HYPERPOLARISATION OF NUCLEAR SPINS 审中-公开
    高分子核激素的方法

    公开(公告)号:WO2016188557A1

    公开(公告)日:2016-12-01

    申请号:PCT/EP2015/061465

    申请日:2015-05-22

    CPC classification number: G01R33/282 G01N24/12 G01R33/26 G01R33/5601 G01R33/62

    Abstract: A method of hyperpolarisation of nuclear spins in one or more particle(s) moving relatively to a polarisation structure, wherein a polarisation of electron spins in the polarisation structure is transferred to the nuclear spins in the particle(s), wherein for one or more of the moving particle(s) within 20 nm from a surface of the polarisation structure, the correlation time of the interaction with the nearest polarisation structure electron spin due to the molecular motion is larger than the inverse of the nuclear Larmor frequency; the electron spins in the polarisation structure are polarised above thermal equilibrium; and the polarisation transfer is performed resonantly.

    Abstract translation: 在相对于偏振结构移动的一个或多个颗粒中的核自旋的超极化的方法,其中偏振结构中的电子自旋的极化被转移到颗粒中的核自旋,其中对于一个或多个 的移动粒子距离偏振结构的表面20nm以内,与分子运动相关的最近偏振结构电子自旋的相互作用时间大于核拉莫尔频率的倒数; 偏振结构中的电子自旋极化高于热平衡; 并且共振地进行极化转移。

    METHOD OF IMPLANTING ATOMS IN A SUBSTRATE AND METHOD OF FORMING A QUANTUM REGISTER

    公开(公告)号:WO2023073060A1

    公开(公告)日:2023-05-04

    申请号:PCT/EP2022/080005

    申请日:2022-10-26

    Abstract: A methods of implanting atoms into a substrate, wherein the atoms are at least some of the constituent atoms of a molecule and wherein the molecule comprises one or more colour centre atom(s) and one or more satellite atom(s). In come embodiments, the molecule comprises not more than three colour centre atoms of the same element of the group. In some embodiments, the molecule comprises one or more colour centre atom(s) other than N, on other embodiments, the molecule comprises at least 6 satellite atoms of N. In some embodiments, the molecule comprises one or more satellite atoms other than 13C. A method of manufacturing a quantum register comprising a colour centre and at least one nuclear spin isotope atom in a substrate, wherein the colour centre of the quantum register is a colour centre formed by a colour centre atom implanted into the substrate according to one of the above methods. A quantum register comprising such colour centre and at least one nuclear spin isotope atom in a substrate. Finally, a use of a molecule that comprises one or more colour centre atom(s) and one or more satellite atom(s) for the manufacture of a quantum register.

    DITHIOLAN-DERIVATE ZUR IMMOBILISIERUNG VON BIOMOLEKÜLEN AUF EDELMETALLEN UND HALBLEITERN
    7.
    发明申请
    DITHIOLAN-DERIVATE ZUR IMMOBILISIERUNG VON BIOMOLEKÜLEN AUF EDELMETALLEN UND HALBLEITERN 审中-公开
    用于生物分子固定贵重金属和半导体衍生物二硫

    公开(公告)号:WO2003074510A1

    公开(公告)日:2003-09-12

    申请号:PCT/EP2003/001968

    申请日:2003-02-26

    Abstract: Die vorliegende Erfindung betrifft Dithiolan-Derivate der Formel A Konjugate aus den Dithiolan-Derivaten mit organisch-chemischen oder biologisch-chemischen Molekülen, Verfahren zur Herstellung der Dithiolan-Derivate und der Konjugate, eine beschichtete Edelmetall- bzw. Halbleiter-Struktur, die ein Edelmetall-beschichtetes Substrat oder einen Halbleiterträger und ein darauf immobilisiertes Dithiolan-Derivat bzw. ein erfindungsgemäßes Konjugat umfasst, einen Biochip, der die erfindungsgemäße Edelmetall- oder Halbleiter-Struktur enthält sowie die Verwendung der erfindungsgemäßen Dithiolan-Derivate zur Immobilisierung von organisch-chemischen oder biologisch-chemischen Molekülen auf Edelmetallen, Edelmetalllegierungen oder Halbleitern.

    Abstract translation: 本发明涉及到与二硫戊环有机化学或生物的化学分子,处理该二硫戊环衍生物的式A缀合物的衍生物用于制备二硫衍生物和缀合物,涂覆贵金属或半导体结构,其包含贵金属 包括涂覆的基板或半导体基板和固定在其上二硫戊环衍生物或本发明的缀合物,包含本发明的贵金属或半导体结构及其有机或化学的固定化使用新颖二硫戊环衍生物的生物芯片biological- 贵金属,贵金属合金或半导体的化学分子。

    SYSTEM AND METHOD FOR ACQUISITION OF A MAGNETIC RESONANCE IMAGE AS WELL AS DEVICE FOR DETERMINING A TRAJECTORY FOR ACQUISITION OF A MAGNETIC RESONANCE IMAGE

    公开(公告)号:WO2022184808A1

    公开(公告)日:2022-09-09

    申请号:PCT/EP2022/055348

    申请日:2022-03-03

    Abstract: The present invention relates to a method (40) for acquisition of a magnetic resonance image independent on an a-priori defined field-of-view (FOV), the method comprising the sequence of steps: determining a k-space trajectory for acquisition of k-space MRI data, wherein said k-space trajectory comprises a field-of-view, FOV, independent 3D k-space trajectory, wherein the 3D k-space trajectory for acquisition of the k-space MRI data is independent of an a-priori defined field-of-view of an MRI image to be constructed, in particular wherein said field-of-view-independent 3D k-space trajectory is based on one or more Jacobi theta functions; acquiring k-space MRI data, wherein a gradient waveform corresponding to said field-of-view independent k-space trajectory is applied to magnetic field gradients of the MRI scanner; and selecting a desired field of view for the magnetic resonance image after acquiring the k-space MRI data and constructing the magnetic resonance image based on the desired field of view from the acquired k-space MRI data.

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