Abstract:
A method of hyperpolarisation of nuclear spins in one or more particle(s) moving relatively to a polarisation structure, wherein a polarisation of electron spins in the polarisation structure is transferred to the nuclear spins in the particle(s), wherein for one or more of the moving particle(s) within 20 nm from a surface of the polarisation structure, the correlation time of the interaction with the nearest polarisation structure electron spin due to the molecular motion is larger than the inverse of the nuclear Larmor frequency; the electron spins in the polarisation structure are polarised above thermal equilibrium; and the polarisation transfer is performed resonantly.
Abstract:
A methods of implanting atoms into a substrate, wherein the atoms are at least some of the constituent atoms of a molecule and wherein the molecule comprises one or more colour centre atom(s) and one or more satellite atom(s). In come embodiments, the molecule comprises not more than three colour centre atoms of the same element of the group. In some embodiments, the molecule comprises one or more colour centre atom(s) other than N, on other embodiments, the molecule comprises at least 6 satellite atoms of N. In some embodiments, the molecule comprises one or more satellite atoms other than 13C. A method of manufacturing a quantum register comprising a colour centre and at least one nuclear spin isotope atom in a substrate, wherein the colour centre of the quantum register is a colour centre formed by a colour centre atom implanted into the substrate according to one of the above methods. A quantum register comprising such colour centre and at least one nuclear spin isotope atom in a substrate. Finally, a use of a molecule that comprises one or more colour centre atom(s) and one or more satellite atom(s) for the manufacture of a quantum register.
Abstract:
The invention concerns a method for the hyperpolarisation of 13 C nuclear spin in a diamond, comprising an optical pumping step, in which colour centre electron spins in the diamond are optically pumped. The method further comprises a transfer step in which the polarisation of a long-lived state of the colour centre electron spins is transferred to 13 C nuclear spins in the diamond via a long-range interaction.
Abstract:
The invention relates to a structure with a core and a coating imprinted with a specific molecule, wherein the structure is a nanoparticle. The invention further relates to the use of such a structure in an imaging method, in a method for the localised induction of hyperthermia and for the separation and/or isolation of cells, protein and/or nucleic acids. Furthermore, the invention comprises a method for the production of such a structure and a kit containing such a structure.
Abstract:
A sensor (1, 2, 3, 4, 5, 6, 7, 8) comprising a first diamond substrate (9) with at least one colour centre (15), the sensor (1, 2, 3, 4, 5, 6, 7, 8) further comprising a first piezomagnetic (10) or piezoelectric primary element (11), which primary element (10, 11) is arranged to interact with the colour centre(s) (15) of the first diamond substrate (9).
Abstract:
The present invention discloses a method for cryopreservation of human spermatozoa: the method comprises providing spermatozoa free from seminal liquid; mixing the spermatozoa with vitrification medium, wherein the main cryoprotectant agent is 0.1 -0.3 M sucrose; placing the sample inside straws and rapidly freezing them; refrigerating the straws with no need of liquid N2; and devitrifying the sample in a medium of the present invention. The present invention furthermore discloses a portable kit that makes easy to implement the method, said kit comprising vitrification and devitrification solutions in the volumes required to develop the method and the physical support to carry out the same, i.e. the straws. The use of this kit is also disclosed for the treatment of disorders related to reproductive failures.
Abstract:
Die vorliegende Erfindung betrifft Dithiolan-Derivate der Formel A Konjugate aus den Dithiolan-Derivaten mit organisch-chemischen oder biologisch-chemischen Molekülen, Verfahren zur Herstellung der Dithiolan-Derivate und der Konjugate, eine beschichtete Edelmetall- bzw. Halbleiter-Struktur, die ein Edelmetall-beschichtetes Substrat oder einen Halbleiterträger und ein darauf immobilisiertes Dithiolan-Derivat bzw. ein erfindungsgemäßes Konjugat umfasst, einen Biochip, der die erfindungsgemäße Edelmetall- oder Halbleiter-Struktur enthält sowie die Verwendung der erfindungsgemäßen Dithiolan-Derivate zur Immobilisierung von organisch-chemischen oder biologisch-chemischen Molekülen auf Edelmetallen, Edelmetalllegierungen oder Halbleitern.
Abstract:
The present invention discloses a method for cryopreservation of human spermatozoa: the method comprises providing spermatozoa free from seminal liquid; mixing the spermatozoa with vitrification medium, wherein the main cryoprotectant agent is 0.1 -0.3 M sucrose; placing the sample inside straws and rapidly freezing them; refrigerating the straws with no need of liquid N2; and devitrifying the sample in a medium of the present invention. The present invention furthermore discloses a portable kit that makes easy to implement the method, said kit comprising vitrification and devitrification solutions in the volumes required to develop the method and the physical support to carry out the same, i.e. the straws. The use of this kit is also disclosed for the treatment of disorders related to reproductive failures.
Abstract:
The present invention discloses a method for cryopreservation of human spermatozoa: the method comprises providing spermatozoa free from seminal liquid; mixing the spermatozoa with vitrification medium, wherein the main cryoprotectant agent is 0.1 -0.3 M sucrose; placing the sample inside straws and rapidly freezing them; refrigerating the straws with no need of liquid N2; and devitrifying the sample in a medium of the present invention. The present invention furthermore discloses a portable kit that makes easy to implement the method, said kit comprising vitrification and devitrification solutions in the volumes required to develop the method and the physical support to carry out the same, i.e. the straws. The use of this kit is also disclosed for the treatment of disorders related to reproductive failures.
Abstract:
The present invention relates to a method (40) for acquisition of a magnetic resonance image independent on an a-priori defined field-of-view (FOV), the method comprising the sequence of steps: determining a k-space trajectory for acquisition of k-space MRI data, wherein said k-space trajectory comprises a field-of-view, FOV, independent 3D k-space trajectory, wherein the 3D k-space trajectory for acquisition of the k-space MRI data is independent of an a-priori defined field-of-view of an MRI image to be constructed, in particular wherein said field-of-view-independent 3D k-space trajectory is based on one or more Jacobi theta functions; acquiring k-space MRI data, wherein a gradient waveform corresponding to said field-of-view independent k-space trajectory is applied to magnetic field gradients of the MRI scanner; and selecting a desired field of view for the magnetic resonance image after acquiring the k-space MRI data and constructing the magnetic resonance image based on the desired field of view from the acquired k-space MRI data.