公开(公告)号：WO0230337A3

公开(公告)日：2002-07-25

申请号：PCT/US0131821

申请日：2001-10-11

Applicant: MASON MICHAEL D

Inventor： MASON MICHAEL D

IPC: A61L27/00 ,  A61F2/00 ,  A61F2/28 ,  A61F2/30 ,  A61F2/44

CPC classification number: A61F2/447 ,  A61F2/28 ,  A61F2/30767 ,  A61F2/30965 ,  A61F2/442 ,  A61F2002/2817 ,  A61F2002/30131 ,  A61F2002/30153 ,  A61F2002/30224 ,  A61F2002/30769 ,  A61F2002/30808 ,  A61F2002/30879 ,  A61F2002/30883 ,  A61F2002/30884 ,  A61F2230/0013 ,  A61F2230/0019 ,  A61F2230/0069 ,  A61F2310/00023 ,  A61F2310/00293 ,  A61F2310/00359 ,  A61F2310/00796 ,  A61F2310/00976

Abstract: A graftless spinal implant for mechanically attaching two adjacent vertebrae includes a body having first and second opposite surfaces. The first and second surfaces include at least one protruding member for securing the body to adjacent vertebrae, wherein the exterior surfaces of the body and the first and second protruding members include a bioactive coating. The bioactive coating can be selected from coatings such as for example, hydroxyapatite. The exterior bioactive coating facilitates the ongrowth/ingrowth of vertebral bone between the implantable spinal fusion device and adjacent vertebrae. Advantageously, this allows the device to avoid the use of a bone graft and/or bone growth agents.

Abstract translation: 用于机械连接两个相邻椎骨的无移植脊柱植入物包括具有第一和第二相对表面的主体。 第一表面和第二表面包括用于将本体固定到相邻椎骨的至少一个突出构件，其中本体的外表面以及第一突出构件和第二突出构件包括生物活性涂层。 生物活性涂层可以选自涂层，例如羟基磷灰石。 外部生物活性涂层有助于植入式脊柱融合装置和相邻椎骨之间的椎骨的生长/向内生长。 有利地，这允许装置避免使用骨移植物和/或骨生长剂。

公开(公告)号：WO0203885A3

公开(公告)日：2002-06-20

申请号：PCT/US0121831

申请日：2001-07-10

Applicant: MICHELSON GARY K

Inventor： MICHELSON GARY K

IPC: A61B17/17 ,  A61B17/80 ,  A61B17/86 ,  A61B17/88 ,  A61F2/00 ,  A61F2/02 ,  A61F2/28 ,  A61F2/30 ,  A61F2/44 ,  A61F2/46 ,  A61B17/70

CPC classification number: A61F2/442 ,  A61B17/1757 ,  A61B17/8042 ,  A61B17/86 ,  A61B17/8875 ,  A61F2/30767 ,  A61F2/4455 ,  A61F2/4465 ,  A61F2/4611 ,  A61F2/4637 ,  A61F2002/2817 ,  A61F2002/2835 ,  A61F2002/30062 ,  A61F2002/30187 ,  A61F2002/30266 ,  A61F2002/30405 ,  A61F2002/30476 ,  A61F2002/30512 ,  A61F2002/30517 ,  A61F2002/30578 ,  A61F2002/30769 ,  A61F2002/30774 ,  A61F2002/30777 ,  A61F2002/30785 ,  A61F2002/30787 ,  A61F2002/4475 ,  A61F2002/4627 ,  A61F2002/4638 ,  A61F2002/4642 ,  A61F2210/0004 ,  A61F2220/0025 ,  A61F2230/0034 ,  A61F2230/0082 ,  A61F2310/00023 ,  A61F2310/00179 ,  A61F2310/0052 ,  Y10S606/907 ,  Y10S606/909 ,  Y10S623/908

Abstract: A flanged interbody spinal implant (100) for insertion at least in part between adjacent vertebral bodies has opposed upper (110) and lower (112) surfaces adapted to contact each of the adjacent vertebral bodies from within the disc space, a leading end (102) for insertion between the adjacent vertebral bodies, and a trailing end (104) opposite the leading end. The trailing end has a height greater than the maximum height of the disc space forming a flanged portion (118) adapted to overlie a part of the anterior aspects of the vertebral bodies adjacent and proximate the disc space to be fused. The flanged portion has at least two bone screw receiving holes (124), at least one each adapted to overlie each of the adjacent vertebral bodies at least in part. The implant has at least one locking element (130) to lock one or more of the bone screws inserted in the bone screw receiving holes.

Abstract translation: 用于至少部分插入相邻椎体之间的凸缘椎体间脊柱植入物（100）具有适于从椎间盘空间内接触每个相邻椎体的相对的上（110）和下（112）表面，前端（102 ）用于插入相邻椎体之间，以及与前端相对的尾端（104）。 后端的高度大于形成凸缘部分（118）的盘状空间的最大高度，所述凸缘部分适于覆盖邻近和接近待熔合盘状空间的椎体的一部分前方面。 凸缘部分具有至少两个骨螺钉接收孔（124），每个至少一个适于至少部分地覆盖每个相邻椎体。 植入物具有至少一个锁定元件（130）以锁定插入骨螺钉接收孔中的一个或多个骨螺钉。

公开(公告)号：WO99030651A1

公开(公告)日：1999-06-24

申请号：PCT/US1998/026128

申请日：1998-12-09

IPC: A61F2/00 ,  A61F2/30 ,  A61F2/44

CPC classification number: A61F2/442 ,  A61F2/3094 ,  A61F2002/30069 ,  A61F2002/30112 ,  A61F2002/30131 ,  A61F2002/30187 ,  A61F2002/3023 ,  A61F2002/30563 ,  A61F2002/30574 ,  A61F2002/30769 ,  A61F2002/30805 ,  A61F2002/30878 ,  A61F2002/30879 ,  A61F2002/30884 ,  A61F2002/30957 ,  A61F2002/30967 ,  A61F2230/0004 ,  A61F2230/0013 ,  A61F2230/0034 ,  A61F2230/0069 ,  A61F2310/00023 ,  A61F2310/00407

Abstract: A spinal disc prosthesis (10) includes an upper rigid plate (20) having an outer perimeter (83) and a lower rigid plate (120) having an outer perimeter (183). A body (200) of elastomeric material is located between and bonded to upper and lower rigid plates (83, 183) and includes a main portion (201) and a peripheral portion (203). Upper and lower plates (83, 183) each have a curved convex plate surface (82, 182). Peripheral portion (203) has a first part (208) which is bonded to curved convex plate surfaces (82, 182) of upper and lower plates (20, 120) and extends toward main portion (201). First part (208) increases in thickness as first part (208) extends toward main portion (201).

Abstract translation: 脊椎椎盘假体（10）包括具有外周（83）的上刚性板（20）和具有外周（183）的下刚性板（120）。 弹性体材料的本体（200）位于上部和下部刚性板（83,183）之间并且结合到主体部分（201）和周边部分（203）上。 上板和下板（83,183）各自具有弯曲的凸板表面（82,182）。 外周部（203）具有与上板（20,120）的弯曲凸板面（82,182）接合并朝向主体部（201）延伸的第一部分（208）。 第一部分（208）随着第一部分（208）朝着主要部分（201）延伸而增加。

公开(公告)号：WO1993000870A1

公开(公告)日：1993-01-21

申请号：PCT/US1992005112

申请日：1992-06-12

Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

Inventor： THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA ,  DUCHEYNE, Paul ,  WOLFARTH, Debra

IPC: A61F02/28

CPC classification number: A61F2/30767 ,  A61F2/30771 ,  A61F2/367 ,  A61F2002/30322 ,  A61F2002/30769 ,  A61F2250/0026 ,  A61F2310/00023 ,  Y10S623/923 ,  Y10T29/49982 ,  Y10T428/12479

Abstract: Orthopaedic implants (110) exhibiting improved fatigue strength are disclosed. By forming a plurality of nodules (100) on the surface of an implant and depositing a porous coating (114) onto the surface of these nodules, the fatigue strength of implants such as those made from α + β titanium alloys, e.g., Ti-6A1-4V alloy is substantially improved. The present invention provides a novel geometry which substantially reduces the stress concentration factor created by the interfacial geometry of conventional porous coatings. Methods of manufacturing porous coated orthopaedic implants (110) are also disclosed.

公开(公告)号：WO2017098316A1

公开(公告)日：2017-06-15

申请号：PCT/IB2016/001730

申请日：2016-12-07

Applicant: MAGAGNOLI, Augusto

Inventor： MAGAGNOLI, Augusto

IPC: A61F2/32 ,  A61F2/38 ,  A61F2/30

CPC classification number: A61F2/38 ,  A61F2/3094 ,  A61F2/32 ,  A61F2/34 ,  A61F2/3662 ,  A61F2/3859 ,  A61F2/389 ,  A61F2002/2817 ,  A61F2002/30677 ,  A61F2002/3068 ,  A61F2002/30769 ,  A61F2002/30805 ,  A61F2002/30822 ,  A61F2002/30901 ,  A61F2002/30902 ,  A61F2002/30909 ,  A61F2002/368

Abstract: A prosthetic device (1, 100, 200, 300), adapted to be implanted in the human body and adapted to prevent and/or treat an infection that can arise and/or that has arisen in a bone or articulation site, wherein the prosthetic device comprises a prosthetic body (2, 102, 202, 302) provided with at least one surface for coupling, during use, with the bone or articulation site and with at least one cavity (4, 104, 204, 304) placed along the coupling surface, wherein the at least one cavity is adapted to comprise, contain or house at least one pharmaceutical or medical substance (4').

Abstract translation: 一种适于植入人体并适于预防和/或治疗可能出现和/或已经出现的感染的假体装置（1,100,200,300） 骨或关节运动部位，其中所述假体装置包括设置有至少一个表面的假体（2,102,202,302），所述至少一个表面用于在使用期间与所述骨或关节运动部位以及至少一个空腔（4,104 ，204,304），其中所述至少一个空腔适于包括，容纳或容纳至少一种药物或医疗物质（4'）。

公开(公告)号：WO2016005235A1

公开(公告)日：2016-01-14

申请号：PCT/EP2015/064924

申请日：2015-07-01

Applicant: CERAMTEC GMBH

Inventor： PREUSS, Roman ,  RASCHKE, Marita ,  STRÖTGEN, Peter ,  WEISS, Tobias

IPC: A61F2/30 ,  A61L27/10 ,  A61L27/56 ,  A61F2/38

CPC classification number: A61F2/30771 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2/38 ,  A61F2/3859 ,  A61F2/389 ,  A61F2002/30013 ,  A61F2002/30769 ,  A61F2002/3093 ,  A61F2002/30968 ,  A61F2310/00179 ,  A61F2310/00796 ,  A61F2310/00928 ,  A61F2310/00976 ,  A61L27/10 ,  A61L27/16 ,  A61L27/306 ,  A61L27/32 ,  A61L27/34 ,  A61L27/52 ,  A61L27/56 ,  A61L2430/24 ,  C08L23/06 ,  C08L89/00

Abstract: Die Erfindung betrifft einen Kniegelenksersatz mit einer Femurkomponente (1) und einer Tibiakomponente (2), jeweils mit einer das Gelenk bildenden Vorderseite und einer knochenzugewandten Rückseite (4) und mit einem Polyethylen(PE)-Liner (3). Damit der Kniegelenksersatz metallfrei und ohne Zement implantierbar ist, wird vorgeschlagen, dass die Femurkomponente (1) und die Tibiakomponente (2) aus einer Vollkeramik bestehen und mit integrierter poröser osseointegrativen knochenzugewandten Rückseite (4) beider Komponenten (1, 2).

Abstract translation: 本发明涉及一种全膝关节置换的股骨部件（1）和胫骨部件（2），在每种情况下与所述接合前表面和面向骨的背面形成（4）中，用聚乙烯（PE）-Liner（3）。 因此，膝关节置换植入不含金属和没有水泥，建议的是，股骨部件（1）和胫骨部件（2）包括全陶瓷和具有集成的多孔骨结合的骨面向后面（4）两种组分的（1，2）。

公开(公告)号：WO2015191977A1

公开(公告)日：2015-12-17

申请号：PCT/US2015/035518

申请日：2015-06-12

Applicant: GLOBUS MEDICAL, INC.

Inventor： BALASUBRAMANIAN, Anand ,  DWYER, Ed ,  PERETZ, David ,  ANKNEY, David ,  RHODA, William ,  PAUL, David ,  ANGELUCCI, Christopher

IPC: A61F2/44

CPC classification number: A61F2/442 ,  A61B17/1604 ,  A61B17/1671 ,  A61B17/1735 ,  A61B17/1757 ,  A61B2017/0046 ,  A61B2017/0256 ,  A61F2/44 ,  A61F2/4425 ,  A61F2/4611 ,  A61F2/4684 ,  A61F2002/30014 ,  A61F2002/30113 ,  A61F2002/30125 ,  A61F2002/30153 ,  A61F2002/30166 ,  A61F2002/302 ,  A61F2002/30224 ,  A61F2002/30365 ,  A61F2002/30387 ,  A61F2002/30433 ,  A61F2002/30451 ,  A61F2002/30471 ,  A61F2002/30517 ,  A61F2002/30545 ,  A61F2002/30563 ,  A61F2002/30568 ,  A61F2002/30571 ,  A61F2002/30579 ,  A61F2002/30594 ,  A61F2002/30601 ,  A61F2002/30604 ,  A61F2002/30616 ,  A61F2002/30649 ,  A61F2002/30662 ,  A61F2002/30769 ,  A61F2002/30772 ,  A61F2002/30841 ,  A61F2002/30878 ,  A61F2002/30884 ,  A61F2002/30899 ,  A61F2002/3092 ,  A61F2002/30935 ,  A61F2002/443 ,  A61F2002/448 ,  A61F2002/4627 ,  A61F2002/4629 ,  A61F2002/4681 ,  A61F2310/00407 ,  A61F2310/00796

Abstract: The present invention relates generally to a prosthetic spinal disc for replacing a damaged disc between two vertebrae of a spine and methods for inserting said discs. The intervertebral prosthetic discs are provided with connections for facilitating implantation and removal and features which enhance primary and secondary stability over time.

Abstract translation: 技术领域本发明总体上涉及一种用于替换脊柱的两个椎骨之间的损伤椎间盘的假肢脊椎椎间盘和用于插入所述椎间盘的方法。 椎间盘假体椎间盘设置有便于植入和移除的连接以及随时间增强主要和次要稳定性的特征。

公开(公告)号：WO2013123515A1

公开(公告)日：2013-08-22

申请号：PCT/US2013/026742

申请日：2013-02-19

Applicant: MOBIUS MEDICAL LLC

Inventor： EICKMANN, Thomas ,  HAYES, Daniel, E., E., Jr. ,  GROVER, Sterling, R.

IPC: A61F2/38

CPC classification number: A61F2/389 ,  A61B17/86 ,  A61F2/30749 ,  A61F2002/30387 ,  A61F2002/30405 ,  A61F2002/30769 ,  A61F2002/30894

Abstract: Apparatus for reconstructing a joint, the apparatus comprising: an implant body having a bone contacting surface; and a plurality of fixation elements secured to the implant body and extending into the host bone at a plurality of angles, wherein all angles are not equal to one another, so as to create immediate stability between the implant body and the host bone.

Abstract translation: 用于重建关节的装置，所述装置包括：具有骨接触面的植入体; 以及多个固定元件，其固定到所述植入体并以多个角度延伸到所述主体骨中，其中所有角度彼此不相等，以便在所述植入体和所述主体骨之间产生立即的稳定性。

公开(公告)号：WO2013033584A3

公开(公告)日：2013-04-25

申请号：PCT/US2012053423

申请日：2012-08-31

Applicant: IN QUEUE INNOVATIONS LLC ,  FESSLER DR RICHARD G ,  BOGER JOHN W ,  BONO FRANK S

Inventor： FESSLER DR RICHARD G ,  BOGER JOHN W ,  BONO FRANK S

IPC: A61B17/70 ,  A61B17/86 ,  A61B17/88 ,  A61F2/44 ,  A61F2/46

CPC classification number: A61F2/442 ,  A61B17/8042 ,  A61B17/86 ,  A61F2/30767 ,  A61F2/4425 ,  A61F2/446 ,  A61F2/4611 ,  A61F2002/30064 ,  A61F2002/30224 ,  A61F2002/30232 ,  A61F2002/30331 ,  A61F2002/30383 ,  A61F2002/30395 ,  A61F2002/30433 ,  A61F2002/30492 ,  A61F2002/30504 ,  A61F2002/30517 ,  A61F2002/30528 ,  A61F2002/30607 ,  A61F2002/30616 ,  A61F2002/30649 ,  A61F2002/30655 ,  A61F2002/30662 ,  A61F2002/30769 ,  A61F2002/30782 ,  A61F2002/30787 ,  A61F2002/30808 ,  A61F2002/30822 ,  A61F2002/3085 ,  A61F2002/30858 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00179 ,  A61F2310/00796

Abstract: A disc replacement device including a first body member with a convex articulation surface and a second body member with a concave articulation surface is disclosed. When operably positioned, the convex articulation surface engages the concave articulation surface to provide for movement therebetween. The disc replacement device also includes a first opening in the first body member and a second opening in the second body member, wherein the openings are angled and extends from the front aspects of the body members through the external surfaces. The disc replacement device further includes at least two bone fasteners for insertion into the first and second openings to secure the disc replacement device to a first and second vertebra. An interbody motion device and fusion implant, as well as a surgical method for implantation are also disclosed.

Abstract translation: 公开了一种盘替换装置，其包括具有凸形关节表面的第一本体构件和具有凹形铰接表面的第二本体构件。 当可操作地定位时，凸起的关节表面接合凹形铰接表面以提供它们之间的运动。 盘替换装置还包括在第一主体构件中的第一开口和第二主体构件中的第二开口，其中开口成角度并且通过外表面从主体构件的前部方面延伸。 盘更换装置还包括至少两个用于插入第一和第二开口的骨固定件，以将椎间盘置换装置固定到第一和第二椎骨。 还公开了一种体内运动装置和融合植入物，以及用于植入的手术方法。

公开(公告)号：WO2012024266A1

公开(公告)日：2012-02-23

申请号：PCT/US2011/047869

申请日：2011-08-16

Applicant: ASCENSION ORTHOPEDICS, INC. ,  RITZ, Joseph P. ,  SCOTT, Clive

Inventor： RITZ, Joseph P. ,  SCOTT, Clive

IPC: A61F2/30 ,  A61F2/40 ,  A61F2/42 ,  A61L27/30

CPC classification number: A61L27/08 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2/4003 ,  A61F2/4241 ,  A61F2002/30163 ,  A61F2002/30299 ,  A61F2002/30769 ,  A61F2002/30929 ,  A61F2002/3098 ,  A61F2002/4007 ,  A61F2002/4248 ,  A61F2002/4251 ,  A61F2230/0028 ,  A61F2230/0093 ,  A61F2310/00173 ,  A61F2310/00407 ,  A61F2310/00485 ,  A61F2310/00491 ,  A61F2310/00497 ,  A61F2310/00544 ,  A61F2310/0055 ,  A61F2310/00574 ,  A61L27/303 ,  A61L27/306 ,  A61L2430/02

Abstract: Methods for forming bone implants for the repair of the ends of bones at orthopedic joints, which implants have a Young's modulus close to that of human cortical bone. Substrates of dense isotropic graphite are coated overall with hard, microporous, isotropic pyrocarbon of specific character such that it can be polished to serve as an articular surface and can also securely receive an anchoring first metal layer through PVD. The first layer has a character such that, by thermal spraying a second biocompatible metal layer thereupon, fusion occurs and thereby anchors an outermost layer that is formed with a network of randomly interconnected pores and a surface character of peaks and valleys designed to promote enhanced appositional growth of cortical bone at the interface therewith.

Abstract translation: 用于形成用于修复矫形关节骨头端部的骨植入物的方法，所述植入物的杨氏模量接近人类皮质骨的杨氏模量。 致密各向同性石墨的基体整体涂覆有特定特性的硬质，微孔，各向同性的热解碳，使得其可以被抛光以用作关节表面，并且还可以通过PVD可靠地接收固定的第一金属层。 第一层具有这样的特征，使得通过热喷涂第二生物相容性金属层，发生融合，从而锚定形成有随机互连孔的网络的最外层和设计用于促进增强的附着的峰和谷的表面特征 皮质骨与其界面的生长。