Abstract:
A dressing (100) for applying compression to a wound (14) in a patient includes a bladder (102) having a non-deformable end wall (104) and a deformable membrane (106). The dressing may include a flexible web (110) having an adhesive layer (120) on one side thereof for securing the dressing to the patient so as to hold the bladder against the patient's skin. Upon inflation, the deformable membrane projects towards the patient's skin and exerts pressure on the wound to reduce the flow of blood from the wound.
Abstract:
A vascular graft comprising a traditional graft material and an electrospun fibrous layer. The solvent used to reduce the material for the electrospun layer is also capable of reducing the graft material to a liquid solution. The electrospun layer is chemically bonded to the graft material, without adhesives, by either spraying the graft with the solvent prior to electrospinning or by assuring that a sufficient amount of residual solvent reaches the graft while electrospinning.
Abstract:
A balloon catheter (10) having a microamanometer (22) connected to the catheter (10) and also a fluid-filled transducer system for adjusting micromanometer pressure measurements.
Abstract:
A vacuum reservoir, for use with an intra-aortic balloon pump or orther system (1),containing a muffling means (40) having a honeycom-like cell structure or other flow straightening structure.
Abstract:
An improved intra-aortic balloon catheter system comprising an insertion sheath (20), having an expandable distal end (70), and a tapered balloon membrane (40) capable of being removed through said insertion sheath (20) upon completion of therapy. The outer diameter of the balloon membrane (40) in a wrapped state is smaller than the outer diameter of the outer tube (30).
Abstract:
An improved intra-aortic balloon catheter (30) with a balloon membrane (34), a tip (40), a co-lumen extruded tube (32) having an inner lumen (68) whose proximal portion lies between the inner and outer surfaces of the co-lumen extruded tube (32) and whose distal portion is defined by the inner surface of a Nitinol inner tube (38), and a retainer (82). The co-lumen extruded tube (32) material is 0-70 % by weight a PELLETHANE material having a hardness of 75D, 30-60 % by weight a PELLETHANE material having a hardness of 65D, and 0-50 % by weight a Pellethane material having a hardness of 55D. The tip (40) has a bulbous portion (43) and is made from ESTANE material group 58887 and has a hardness less than or equal to 90A so as to allow for better guide wire tracking. The balloon membrane (34) is coated with silicone liquid, such as MDX, and has a double-wall thickness within a range of 0.006 inches to 0.0008 inches so as to allow for a tighter wrap of the ballon membrane (34) about the Nitinol inner tube (38). The retainer (82) is made from a low friction PTFE material, such as Teflon, so as to allow for easy removal of the tightly wrapped balloon membrane (34). The retainer (82) also has wings (84) which snap under horizontal ribs (146) and fit between vertical ribs (144) in an improved packaging tray (138) and thereby secure the retainer (82) within said improved packaging tray (138).
Abstract:
An impeller (605) includes a hub (610) and at least one blade (612) supported by the hub. The impeller has a stored configuration in which the blade is compressed so that its distal end moves towards the hub, and a deployed configuration in which the blade extends away from the hub. The impeller may be part of a pump for pumping fluids, such as pumping blood within a patient. A blood pump (600) may include a cannula (625) having a proximal portion (623) with a fixed diameter, and a distal portion (626) with an expandable diameter. The impeller may reside in the expandable portion of the cannula. The cannula may have a compressed diameter which allows it to be inserted percutaneously into a patient. Once at a desired location, the expandable portion of the cannula may be expanded and the impeller expanded to the deployed configuration. A flexible drive shaft (630) may extend through the cannula for rotationally driving the impeller within the patient's body.
Abstract:
Methods for assay and/or amplification of nucleic acid sequences. An amplification procedure is provided for use with RNA samples that do not have a poly A sequence on the 3 prime end of the messenger RNA as is the case for bacterial, and other total RNA sources. Further, a method is provided for coupling, via ligation, a nucleic acid sequence to the 5 prime end of a random or sequence specific primer or to the 3 prime or 5 prime end of a synthesized DNA probe or target sequence, preferably to enable labelling of the target sequence or amplification thereof.
Abstract:
A double lumen continuous flow dialysis needle (1) and cannula (20) having a contiguous lumens (2, 3) of different lengths, the shorter lumen acting as blood intake lumen and the longer as the blood return lumen, each lumen (2, 3) having a beveled edge (4, 5) sloping outwardly and away from the needle (1) which can be inserted percutaneously and which minimizes the possibility of mixing cleansed blood with blood entering the intake lumen.
Abstract:
A double lumen continuous flow dialysis needle and cannula having contiguous lumens of different lengths, the shorter lumen acting as blood intake lumen and the longer as a blood return lumen, each lumen having a beveled edge sloping outwardly and away from the needle which can be inserted percutaneously and wich minimizes the possibility of mixing cleansed blood with blood entering the intake lumen.