公开(公告)号：WO2007044993A2

公开(公告)日：2007-04-19

申请号：PCT/US2006/040695

申请日：2006-10-12

Applicant: GENENCOR INTERNATIONAL, INC. ,  THE PROCTER AND GAMBLE COMPANY ,  SHAW, Andrew ,  WALLACE, Louise ,  ESTELL, David A. ,  HOMMES, Ronald ,  LEE, Sang-Kyu ,  SADLOWSKI, Eugene Steven ,  OH, Hiroshi

Inventor： SHAW, Andrew ,  WALLACE, Louise ,  ESTELL, David A. ,  HOMMES, Ronald ,  LEE, Sang-Kyu ,  SADLOWSKI, Eugene Steven ,  OH, Hiroshi

IPC: C07K14/43

CPC classification number: C12N9/54 ,  C11D1/02 ,  C11D3/386 ,  C11D3/38663 ,  C12Y304/24

Abstract: The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.

Abstract translation: 本发明提供包含至少一种具有改善的储存稳定性的中性金属蛋白酶的方法和组合物。 在一些实施方案中，中性金属蛋白酶可用于清洁和其它应用。 在一些特别优选的实施方案中，本发明提供了包含从芽孢杆菌属芽孢杆菌获得的中性金属蛋白酶的方法和组合物。 在一些更特别优选的实施方案中，中性金属蛋白酶从解淀粉芽孢杆菌获得。 在另外的优选实施方案中，中性金属蛋白酶是解淀粉芽孢杆菌中性金属蛋白酶的变体。 在另外的实施方案中，中性金属蛋白酶是解淀粉芽孢杆菌中性金属蛋白酶的同系物。 本发明特别用于包括但不限于清洁，漂白和消毒的应用。

公开(公告)号：WO2005013874A1

公开(公告)日：2005-02-17

申请号：PCT/US2004/025562

申请日：2004-08-06

Applicant: THE PROCTER AND GAMBLE COMPANY ,  TURNER, Robert, Haines ,  BREIDENBACH, Vincent, Sean ,  O'DONNELL, Hugh, Joseph ,  BENSON, Douglas, Herrin

Inventor： TURNER, Robert, Haines ,  BREIDENBACH, Vincent, Sean ,  O'DONNELL, Hugh, Joseph ,  BENSON, Douglas, Herrin

IPC: A61F13/15

CPC classification number: A61F13/512 ,  A61F13/15731 ,  A61F2013/51147 ,  B26F1/18 ,  B26F1/20 ,  B26F1/24 ,  B29C55/18 ,  B29C59/022 ,  B29C59/04 ,  B29K2105/256 ,  Y10T428/24273

Abstract: An apertured film web is disclosed. The web comprises a plurality of first regions (2) having a first molecular orientation and a plurality of second regions (4) having a second molecular orientation, the first and second regions being in an alternating and contiguous generally linear relationship in a first direction, the second molecular orientation being generally orthogonal to the first direction, and wherein the second region comprises openings defining apertures (6) therein.

Abstract translation: 公开了一种多孔膜网。 幅材包括具有第一分子取向的多个第一区域（2）和具有第二分子取向的多个第二区域（4），第一和第二区域在第一方向上呈交替和连续的大致线性关系， 所述第二分子取向大致垂直于所述第一方向，并且其中所述第二区域包括在其中限定孔（6）的开口。

公开(公告)号：WO2002095419A2

公开(公告)日：2002-11-28

申请号：PCT/US2002/016247

申请日：2002-05-20

Applicant: AMERSHAM BIOSCIENCES AB ,  THE PROCTER AND GAMBLE COMPANY BECKETT RIDGE TECHNICAL CENTER ,  BHIKHABHAI, Ramagauri ,  LIMINGA, Maria ,  MALOISEL, Jean-Luc ,  PALMGREN, Ronnie ,  KEOUGH, Thomas, W. ,  YOUNGQUIST, Robert, S. ,  VAUGHN, Harold, L. ,  YELM, Ken, E.

Inventor： BHIKHABHAI, Ramagauri ,  LIMINGA, Maria ,  MALOISEL, Jean-Luc ,  PALMGREN, Ronnie ,  KEOUGH, Thomas, W. ,  YOUNGQUIST, Robert, S. ,  VAUGHN, Harold, L. ,  YELM, Ken, E.

IPC: G01N33/68

CPC classification number: G01N33/6848 ,  G01N33/58 ,  G01N33/6824 ,  G01N33/6851

Abstract: The present invention relates to a method of identifying a polypeptide, which method comprises the steps of (a) derivatization of the N-terminus of the polypeptide, or the N-termini of one or more peptides of the polypeptide, with at least one acidic reagent which comprises a sulfonyl moiety coupled to an activated acid moiety to provide one or more peptide derivatives; analyzing at least one such derivative using a mass spectrometric technique to provide a fragmentation pattern, and (c) interpreting the fragmentation pattern obtained, wherein the peptide or polypeptide is immobilized to a solid support at least during step(a). Furthermore, the present invention also relates to a kit for identifying a polypeptide by a mass spectrometric technique.

Abstract translation: 本发明涉及一种鉴定多肽的方法，该方法包括以下步骤：（a）使多肽的一个或多个肽的N-末端的N末端或至少一个酸性的 试剂，其包含与活化的酸部分偶联以提供一种或多种肽衍生物的磺酰基部分; 使用质谱技术分析至少一种这样的衍生物以提供分裂模式，和（c）解释获得的断裂模式，其中至少在步骤（a）期间将肽或多肽固定在固体支持物上。 此外，本发明还涉及通过质谱技术鉴定多肽的试剂盒。

公开(公告)号：WO2002095412A2

公开(公告)日：2002-11-28

申请号：PCT/US2002/016244

申请日：2002-05-20

Applicant: AMERSHAM BIOSCIENCES AB ,  THE PROCTER AND GAMBLE COMPANY

Inventor： LIMINGA, Maria ,  MALOISEL, Jean-Luc ,  PALMGREN, Ronnie ,  KEOUGH, Thomas, W. ,  YOUNGQUIST, Robert, S. ,  VAUGHN, Harold, L. ,  YELM, Ken, E.

IPC: G01N33/58

CPC classification number: C07D207/46 ,  G01N33/58 ,  G01N33/6824 ,  G01N2458/15 ,  Y10T436/18

Abstract: The present invention relates to a method of identifying a polypeptide using a class of novel, water-stable reagents. More specifically, the method according to the invention comprises the steps of (a) derivatization in an aqueous solution of the N-terminus of the polypeptide, or the N-termini of one more peptides of the polypeptide, with at least one acidic reagent which comprises a sulfonyl moiety coupled to an activated acid moiety to provide one or more peptide derivatives; (b) analyzing at least one such derivative using a mass spectrometric technique to provide a fragmentation pattern; and (c) interpreting the fragmentation pattern. Furthermore, the present invention also relates to a kit and novel reagents for use in the present method.

Abstract translation: 本发明涉及使用一类新的水稳定试剂鉴定多肽的方法。 更具体地，根据本发明的方法包括以下步骤：（a）将多肽的N末端的水溶液或多肽的多肽的N-末端衍生化至少一种酸性试剂，所述酸性试剂 包括与活化的酸部分偶联的磺酰基部分以提供一种或多种肽衍生物; （b）使用质谱技术分析至少一种此类衍生物以提供分裂模式; 和（c）解释分裂模式。 此外，本发明还涉及用于本方法的试剂盒和新试剂。

公开(公告)号：WO1993003699A2

公开(公告)日：1993-03-04

申请号：PCT/US1992006709

申请日：1992-08-07

Applicant: THE PROCTER AND GAMBLE COMPANY

Inventor： THE PROCTER AND GAMBLE COMPANY ,  YOUNG, Gerald, Alfred ,  LaVON, Gary, Dean ,  TAYLOR, Gregory, Wade

IPC: A61F13/15

CPC classification number: A61L15/425 ,  A61F5/4401 ,  A61F13/49009 ,  A61F13/49466 ,  A61F13/511 ,  A61F13/53 ,  A61F13/532 ,  A61F13/535 ,  A61F13/537 ,  A61F13/53713 ,  A61F13/53747 ,  A61F13/5376 ,  A61F13/5622 ,  A61F2013/15292 ,  A61F2013/15357 ,  A61F2013/15406 ,  A61F2013/15422 ,  A61F2013/1552 ,  A61F2013/15528 ,  A61F2013/5103 ,  A61F2013/51409 ,  A61F2013/5149 ,  A61F2013/530007 ,  A61F2013/530036 ,  A61F2013/530459 ,  A61F2013/530467 ,  A61F2013/530474 ,  A61F2013/530481 ,  A61F2013/530708 ,  A61F2013/530802 ,  A61F2013/53081 ,  A61F2013/530817 ,  A61F2013/530839 ,  A61F2013/530854 ,  A61F2013/8488 ,  A61F2013/8491 ,  Y10T428/24998 ,  Y10T442/647

Abstract: Disclosed are absorbent articles, such as diapers, for the management of incontinence. Such articles utilize in their absorbent cores (50) a fluid acquisition/distribution component (51) and a fluid storage/redistribution component (52) maintained in fluid communication with the acquisition/distribution component. The fluid acquisition/distribution component (51) can be any porous hydrophilic, e.g., fibrous or foam-based material which will provide an initial Fluid Acquisition Rate of at least 2 ml of synthetic urine per second and will also preferably provide a 30-minute Vertical Wicking Height of at least 2 cm. The fluid storage/redistribution component (52) comprises a hydrophilic, flexible, open-celled polymeric foam having a free absorbent capacity of at least about 12 ml of synthetic urine per gram of dry foam and an absorbent capacity under a 5.1 kPa confining pressure which is at least 5 % of this free capacity. Preferred fluid acquisition/distribution component materials comprise chemically stiffened, twisted, curled cellulosic fibers. Preferred fluid storage/redistribution component materials comprise absorbent foams prepared by polymerizing a high internal phase emulsion (HIPE).

Abstract translation: 描述了用于控制失禁的吸收性物品，例如尿布。 这种制品使用两个吸收芯内（50）的流体采集/分配部件（51）和流体的保持流体连通的获取组件的组件储存/再分散（52）/ 流体分布。 采集/分配部件（51）可以由任何亲水性多孔材料制成，例如纤维材料或泡沫，其具有至少2ml合成尿液的初始流体采集速率 每秒并且还优选在30分钟内具有至少2cm的毛细管作用吸收和扩散高度。 流体的组分储存/再分散（52）包括一柔性泡沫和亲水性聚合物的开孔的压力下具有至少约12毫升，每干泡沫的克和吸收容量的合成尿的自由吸收容量 5.1千帕的容量至少是该容量的5％。 优选的流体收集/分配组件材料包括加强的，加捻的和波纹状的纤维素纤维。 优选的流体储存/再分配部件材料包括通过聚合高内相乳液制备的吸收泡沫。

公开(公告)号：WO1992018601A1

公开(公告)日：1992-10-29

申请号：PCT/US1992003156

申请日：1992-04-16

Applicant: MINNESOTA MINING AND MANUFACTURING COMPANY ,  THE PROCTER AND GAMBLE COMPANY

Inventor： MINNESOTA MINING AND MANUFACTURING COMPANY ,  THE PROCTER AND GAMBLE COMPANY ,  MERZ, Russell, J. ,  NORBURY, Robert, J. ,  BUTTERY, Howard, J. ,  MICHAEL, William, R.

IPC: C11D03/50

CPC classification number: A61Q13/00 ,  A23L27/74 ,  A61K8/11 ,  A61K2800/412 ,  C11D3/505 ,  C11D17/0039

Abstract: Perfume particles comprise perfume dispersed within certain water-insoluble nonpolymeric carrier materials and encapsulated in a protective shell by coating with a friable coating material. The coated particles allow for preservation and protection of perfumes which are susceptible to degradation or loss in storage and in cleaning compositions. Such perfume particles exhibit improved performance when they incorporate a modifier material according to this invention. In use, the surface coating fractures and the underlying carrier/perfume particles efficiently deliver a large variety of perfume types of fabrics or other surfaces.

Abstract translation: 香料颗粒包含分散在某些水不溶性非聚合物载体材料中的香料，并通过用易碎涂层材料涂覆而包封在保护壳中。 涂覆的颗粒允许保存和保护易于降解或在储存和清洁组合物中损失的香料。 当它们掺入根据本发明的改性剂材料时，这样的香料颗粒表现出改进的性能。 在使用中，表面涂层断裂和底层载体/香料颗粒有效地传递各种各样的香水类型的织物或其它表面。

公开(公告)号：WO2006129252A2

公开(公告)日：2006-12-07

申请号：PCT/IB2006/051674

申请日：2006-05-25

Applicant: THE PROCTER AND GAMBLE COMPANY ,  JORDAN, IV, Glenn, Thomas ,  DITULLIO, JR., Daniel, Dale

Inventor： JORDAN, IV, Glenn, Thomas ,  DITULLIO, JR., Daniel, Dale

CPC classification number: C11D17/041 ,  A47L13/17 ,  A47L13/20 ,  C11D17/0039 ,  C11D17/049

Abstract: The present invention relates to a cleaning wipe suitable for cleaning a surface comprising a cleaning substrate, and microcapsules comprising an active ingredient. The majority of the microcapsules are located adjacent to at least one point on the perimeter of said cleaning substrate. The present invention also relates to (1) a cleaning kit suitable for cleaning a surface, comprising the cleaning wipe and a cleaning implement, and (2) a method of cleaning a surface, comprising the step of contacting the surface with the cleaning wipe.

Abstract translation: 本发明涉及适用于清洁包括清洁基板的表面的清洁擦拭物和包含活性成分的微胶囊。 大部分微胶囊位于所述清洁基材周边上的至少一个点附近。 本发明还涉及（1）适于清洁表面的清洁套件，包括清洁擦拭物和清洁工具，以及（2）清洁表面的方法，包括使表面与清洁擦拭物接触的步骤。

公开(公告)号：WO2006005767A1

公开(公告)日：2006-01-19

申请号：PCT/EP2005/053385

申请日：2005-07-14

Applicant: GE BAYER SILICONES GMBH & CO. KG ,  THE PROCTER AND GAMBLE COMPANY ,  WAGNER, Roland ,  LANGE, Horst ,  ROOS, Christopher ,  WITOSSEK, Anita ,  MOELLER, Annette ,  STACHULLA, Karl-Heinz ,  SOCKEL, Karl-Heinz ,  GRAYDON, Andrew Russell ,  MARTIN, Julian David ,  BLYTH, Kevin Graham

Inventor： WAGNER, Roland ,  LANGE, Horst ,  ROOS, Christopher ,  WITOSSEK, Anita ,  MOELLER, Annette ,  STACHULLA, Karl-Heinz ,  SOCKEL, Karl-Heinz ,  GRAYDON, Andrew Russell ,  MARTIN, Julian David ,  BLYTH, Kevin Graham

IPC: C08L83/06

CPC classification number: D06M15/643 ,  A61K8/25 ,  A61K8/893 ,  A61K8/898 ,  A61K2800/594 ,  A61Q19/00 ,  C08K3/346 ,  C08L83/06 ,  C08L83/08 ,  C11D3/1253 ,  C11D3/373 ,  C11D3/3742 ,  D06M11/79 ,  D06M15/6436 ,  C08L83/00 ,  C08L2666/54

Abstract: Die Erfindung betrifft Schichtsilikat-enthaltende Polysiloxan-Zusammmensetzungen, Verfahren zur ihrer Herstellung sowie ihre Verwendung zur Behandlung von Substraten.

Abstract translation: 本发明涉及一种层状的含硅酸盐的聚硅氧烷Zusammmensetzungen，它们的制备方法和它们用于治疗基底的用途。

公开(公告)号：WO2003104782A1

公开(公告)日：2003-12-18

申请号：PCT/US2003/018039

申请日：2003-06-06

Applicant: THE PROCTER AND GAMBLE COMPANY

Inventor： SHERMAN, Faiz, Feisal ,  GARTSTEIN, Vladimir ,  KERR, Kendal, William ,  MEYER, Herman, William ,  MCCURDY, Jim, Allen

IPC: G01N22/04

CPC classification number: G01N22/04 ,  A45D7/00 ,  A45D24/10 ,  A45D44/00 ,  A45D2044/007 ,  A46B17/00 ,  G01N33/4833

Abstract: A directional coupler sensor is provided for measuring the moisture content of a substrate, such as hair. The sensor incorporates a high frequency directional coupler having a pair of generally parallel plates defining a coupling gap therebetween. A high frequency signal generator generates an electromagnetic field across the gap with the substrate placed across the coupling gap. The coupled power relates to the moisture content of the substrate. A pressure sensor is provided to ensure that the desired compactness of the substrate across the coupling gap is achieved to obtain accurate, reliable and consistent results.

Abstract translation: 提供了一种定向耦合器传感器，用于测量诸如毛发之类的基底的含水量。 该传感器包括一个高频定向耦合器，具有一对大体上平行的板，它们之间形成一个耦合间隙。 高频信号发生器跨越间隙产生跨越耦合间隙放置的衬底的电磁场。 耦合功率与衬底的水分含量有关。 提供压力传感器以确保跨接合间隙的衬底的期望致密度得以获得准确，可靠和一致的结果。