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    SYSTEMS AND TECHNIQUES FOR MONITORING SUBJECTS
    31.
    发明申请
    SYSTEMS AND TECHNIQUES FOR MONITORING SUBJECTS 审中-公开
    监控项目的系统和技术

    公开(公告)号：WO2012021801A3

    公开(公告)日：2012-05-24

    申请号：PCT/US2011047581

    申请日：2011-08-12

    Applicant: SEVENTH SENSE BIOSYSTEMS INC ,  LEVINSON DOUGLAS A ,  BERNSTEIN HOWARD

    Inventor： LEVINSON DOUGLAS A ,  BERNSTEIN HOWARD

    IPC: G06Q50/00 ,  A61M35/00

    CPC classification number: A61B5/4833 ,  A61B5/1112 ,  A61B5/145 ,  A61B5/14503 ,  A61B5/14514 ,  A61B5/14546 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150175 ,  A61B5/150389 ,  A61B5/150412 ,  A61B5/150503 ,  A61B5/150755 ,  A61B5/150809 ,  A61B5/150824 ,  A61B5/150854 ,  A61B5/150862 ,  A61B5/150969 ,  A61B5/150984 ,  A61B5/15113 ,  A61B5/15125 ,  A61B5/15142 ,  A61B5/154 ,  A61B5/157 ,  A61B5/4839 ,  A61B5/4848 ,  A61B5/6824 ,  A61B10/0045 ,  A61B2010/0009 ,  A61B2010/008 ,  A61M5/1723 ,  A61M37/0015 ,  A61M2037/0023 ,  G06F19/3418 ,  G06F19/3456 ,  G06F19/3468 ,  G06Q20/10 ,  G06Q30/02 ,  G06Q30/0207 ,  G06Q50/22 ,  G16H40/63 ,  Y02A90/22 ,  Y02A90/26

    Abstract: The present invention generally relates to systems and methods for monitoring and/or providing feedback for drugs or other pharmaceuticals taken by a subject. In one aspect, the present invention is directed to devices and methods for determining a species within the skin of a subject; and producing feedback to a subject based on the determination of the species. The feedback may be, for example, visual, audible, tactile, a change in temperature, etc. In some cases, information regarding the determination of the species may be transmitted to another entity, e.g., a health care provider, a computer, a relative, etc., which may then provide feedback to the subject in some fashion. In some cases, the feedback may be directly indicative of the species, e.g., whether the species is present, the concentration of the species, whether a by-product of a reaction involving the species is present, whether a compound affected by the species is present, etc. However, the feedback may also be indirect in some embodiments. For example, the subject may be presented with an external reward, e.g., based on the determination of the species within the skin. For instance, a reward such as cash, coupons, songs, discounts, personal items, etc., may be offered based on the level of compliance of the subject. Still other aspects of the invention are generally directed to kits involving such devices (with or without the drug to be monitored), methods of promoting such systems, or the like.

    Abstract translation: 本发明一般涉及用于监测和/或提供受试者所采取的药物或其他药物的反馈的系统和方法。 一方面，本发明涉及用于确定受试者皮肤内物种的装置和方法; 并根据物种的确定向对象产生反馈。 反馈可以是例如视觉，听觉，触觉，温度变化等。在一些情况下，关于物种的确定的信息可以被传输到另一个实体，例如医疗保健提供者，计算机， 相对等，其然后可以以某种方式向受试者提供反馈。 在一些情况下，反馈可以直接指示物种，例如物种是否存在，物种的浓度，是否存在涉及物种的反应的副产物，受物种影响的化合物是否为 存在等。然而，在一些实施例中，反馈也可以是间接的。 例如，受试者可以例如基于皮肤内物种的确定来呈现外部奖励。 例如，可以基于主体的合规级别来提供诸如现金，优惠券，歌曲，折扣，个人物品等的奖励。 本发明的其它方面通常涉及涉及这种装置的试剂盒（有或没有待监测的药物），促进这种系统的方法等。

    SAMPLING DEVICE INTERFACES
    32.
    发明申请
    SAMPLING DEVICE INTERFACES 审中-公开
    采样设备接口

    公开(公告)号：WO2011088211A3

    公开(公告)日：2011-12-01

    申请号：PCT/US2011021131

    申请日：2011-01-13

    Applicant: SEVENTH SENSE BIOSYSTEMS INC ,  CHICKERING DONALD E ,  DAVIS SHAWN ,  HAGHGOOIE RAMIN ,  BERNSTEIN HOWARD ,  LEVINSON DOUGLAS A

    Inventor： CHICKERING DONALD E ,  DAVIS SHAWN ,  HAGHGOOIE RAMIN ,  BERNSTEIN HOWARD ,  LEVINSON DOUGLAS A

    IPC: A61B5/151

    CPC classification number: A61B5/14532 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150236 ,  A61B5/150244 ,  A61B5/150297 ,  A61B5/150389 ,  A61B5/150412 ,  A61B5/150503 ,  A61B5/150755 ,  A61B5/150969 ,  A61B5/150977 ,  A61B5/150984 ,  A61B5/15105 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15125 ,  A61B5/15144 ,  A61B5/15186 ,  A61B5/157 ,  A61B5/685

    Abstract: The present invention generally relates to systems and methods for delivering and/or withdrawing a substance or substances such as blood or interstitial fluid, from subjects, e.g., from the skin and/or from beneath the skin. In one aspect, the present invention is generally directed to devices and methods for withdrawing or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a fluid transporter (for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some cases, the device may be self- contained, and in certain instances, the device can be applied to the skin, and activated to withdraw blood from the subject. The device, in some cases, may be interfaced with external equipment to determine an analyte contained within a fluid contained within or collected by the device. For example, the device may be mounted or engaged on an external holder, the device may include a port for transporting fluid out of the device, the device may include a window for interrogating a fluid contained within the device, or the like. The device, or a portion thereof, may then be processed to determine the blood and/or an analyte within the blood, alone or with an external apparatus. For example, blood may be withdrawn from the device, and/or the device may contain sensors or agents able to determine the blood and/or an analyte suspected of being contained in the blood. Other aspects of the present invention are directed at other devices for withdrawing blood (or other bodily fluids, e.g., interstitial fluid), kits involving such devices, methods of making such devices, methods of using such devices, and the like.

    Abstract translation: 本发明一般涉及用于递送和/或从皮肤和/或皮肤下方的受试者递送和/或从物质或诸如血液或间质液体中取出物质的方法。 一方面，本发明一般涉及使用包含流体转运器（例如，一个或多个微针）的装置从例如皮肤和/或从皮肤下面抽出或提取血液的装置和方法 ）和在接收血液之前具有小于大气压的内部压力的储存室。 在一些情况下，该装置可以是自包含的，并且在某些情况下，可以将该装置应用于皮肤并被激活以从受试者中抽出血液。 在一些情况下，该装置可以与外部设备接口以确定包含在装置内或由装置收集的流体中的分析物。 例如，该装置可以安装或接合在外部支架上，该装置可以包括用于将流体输送出装置的端口，该装置可包括询问包含在装置内的流体等的窗口。 然后可以处理装置或其一部分，以单独或与外部装置一起确定血液和/或血液中的分析物。 例如，血液可以从装置中取出，和/或装置可以包含能够确定血液和/或怀疑包含在血液中的分析物的传感器或试剂。 本发明的其它方面涉及用于抽出血液（或其他体液，例如间质液）的其他装置，涉及这种装置的试剂盒，制造这种装置的方法，使用这种装置的方法等。

    DIAGNOSTIC INFORMATION GENERATION AND USE
    34.
    发明申请
    DIAGNOSTIC INFORMATION GENERATION AND USE 审中-公开
    诊断信息的生成和使用

    公开(公告)号：WO2009017697A3

    公开(公告)日：2009-04-09

    申请号：PCT/US2008009094

    申请日：2008-07-28

    Applicant: T2 BIOSYSTEMS INC ,  LOWERY JR THOMAS J ,  ELSTROM TUAN A ,  LEVINSON DOUGLAS A ,  KOZIARZ JAMES J

    Inventor： LOWERY JR THOMAS J ,  ELSTROM TUAN A ,  LEVINSON DOUGLAS A ,  KOZIARZ JAMES J

    IPC: G06F19/00

    CPC classification number: G06F19/3418 ,  G06Q50/22 ,  G16H50/20 ,  G16H50/80 ,  Y02A90/22 ,  Y02A90/24 ,  Y02A90/26

    Abstract: This invention relates generally to a process for producing machine readable contextual diagnostic information and use of contextual diagnostic information for generating tangible and useful results. The process provides the highest level of integration of diagnostic information collected in a distributed or centralized system comprising diagnostic devices and a global computer network. More particularly, in certain embodiments, contextual diagnostic information are used in specific diagnostic related applications and business models including ecommerce.

    Abstract translation: 本发明一般涉及用于产生机器可读的上下文诊断信息和使用上下文诊断信息来产生有形和有用的结果的过程。 该流程提供了在包含诊断设备和全球计算机网络的分布式或集中式系统中收集的诊断信息的最高级别集成。 更特别地，在某些实施例中，上下文诊断信息用于包括电子商务的特定诊断相关应用和商业模型中。

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