公开(公告)号：WO2010117922A1

公开(公告)日：2010-10-14

申请号：PCT/US2010/029895

申请日：2010-04-05

Applicant: MALLINCKRODT INC. ,  FAGO, Frank, M.

Inventor： FAGO, Frank, M.

IPC: A61M5/14

CPC classification number: A61M5/14546 ,  A61B6/548 ,  A61M5/007 ,  A61M5/1408 ,  A61M5/16881 ,  A61M39/10 ,  A61M2005/14553 ,  A61M2205/273 ,  A61M2205/583 ,  Y10T137/8326

Abstract: A single-use, single-patient, or patient-specific tubing set (300) is disclosed. The tubing set (300) includes at least one check valve (304), along with a use indicator (320). This use indicator (320) provides a visual indication when the tubing set (300) has been used for an injection. In this regard, a piston (340) moves from one position to another when exposed to a certain fluid pressure.

Abstract translation: 公开了单次使用，单一患者或患者特异性管组（300）。 管组（300）包括至少一个止回阀（304）以及使用指示器（320）。 当使用管道组件（300）进行注射时，该使用指示器（320）提供视觉指示。 在这方面，当暴露于某一流体压力时，活塞（340）从一个位置移动到另一个位置。

公开(公告)号：WO2009045714A1

公开(公告)日：2009-04-09

申请号：PCT/US2008/076593

申请日：2008-09-17

Applicant: MALLINCKRODT INC. ,  FAGO, Frank, M. ,  GIBBS, Jonathan, D.

Inventor： FAGO, Frank, M. ,  GIBBS, Jonathan, D.

IPC: A61M5/145

CPC classification number: A61M5/1458 ,  A61M5/14546 ,  A61M5/14566 ,  A61M2005/14553

Abstract: A ram assembly (110) for a power injector (10) is disclosed having an inner ram (120) that is movable relative to an outer ram (140). One or more ram couplers (158) each include a cam slot (164) and are slidably interconnected with an end (150) of the outer ram (140). The inner ram (120) includes a cam (128) that is disposed within a cam slot (164) of its corresponding ram coupler (158). Relative movement between the inner ram (120) and the outer ram (140) moves the various ram couplers (158) relative to the outer ram end (150) by the camming effect between the cams (128) and the cam slots (164). The ram couplers (158) may be used to establish both a coupled state and an uncoupled state or condition with a syringe plunger coupler (34) of a syringe plunger (32) for a power injector syringe (28).

Abstract translation: 公开了一种用于动力注射器（10）的冲头组件（110），其具有可相对于外部冲头（140）移动的内部冲头（120）。 一个或多个压头联接器（158）各自包括凸轮槽（164）并且与外部冲头（140）的端部（150）可滑动地互连。 内部冲头（120）包括设置在其对应的柱塞联接器（158）的凸轮槽（164）内的凸轮（128）。 通过凸轮（128）和凸轮槽（164）之间的凸轮作用，内部冲头（120）和外部冲头（140）之间的相对运动相对于外部冲头端部（150）移动各种压头联接器（158） 。 活塞联接器（158）可用于与用于动力注射器注射器（28）的注射器柱塞（32）的针筒柱塞联接器（34）一起建立耦合状态和非耦合状态或状态。

公开(公告)号：WO2009026060A3

公开(公告)日：2009-02-26

申请号：PCT/US2008/072978

申请日：2008-08-13

Applicant: MALLINCKRODT INC. ,  WAGNER, Gary, S. ,  FAGO, Frank, M. ,  STAATS, Peter ,  BATTIATO, Dane

Inventor： WAGNER, Gary, S. ,  FAGO, Frank, M. ,  STAATS, Peter ,  BATTIATO, Dane

IPC: A61M5/145 ,  A61M5/142

Abstract: Some injectors of the invention may include a fluid drive (18) responsive to pressure of a working fluid (e.g., liquid, pneumatic, or both) to impart a sequence of forces to drive a delivery device (22) (e.g., a syringe) to deliver a medical fluid (e.g., a contrast agent, a radiopharmaceutical, a drug, or a combination thereof). Some injectors may include a multimedia tube configured to pass a working fluid (e.g., air) and a light signal (e.g., infrared). Some injectors may include a peristaltic drive responsive to pressure of a working fluid.

公开(公告)号：WO2008137375A2

公开(公告)日：2008-11-13

申请号：PCT/US2008/061722

申请日：2008-04-28

Applicant: MALLINCKRODT INC. ,  FAGO, Frank, M. ,  KNIPFER, James, E.

Inventor： FAGO, Frank, M. ,  KNIPFER, James, E.

IPC: A61M5/00 ,  A61M5/168 ,  A61M5/172

CPC classification number: A61M31/005 ,  A61B6/481 ,  A61B6/504 ,  A61M5/007 ,  A61M5/14546 ,  A61M5/14566 ,  A61M5/172 ,  A61M2005/14208 ,  A61M2205/3362 ,  A61M2205/6018 ,  A61M2205/6054 ,  A61M2205/70

公开(公告)号：WO2008127588A1

公开(公告)日：2008-10-23

申请号：PCT/US2008/004537

申请日：2008-04-08

Applicant: MALLINCKRODT INC. ,  FAGO, Frank, M. ,  NEER, Charles, S.

Inventor： FAGO, Frank, M. ,  NEER, Charles, S.

IPC: A61M5/145 ,  A61M5/31

CPC classification number: A61M5/14546 ,  A61M5/007 ,  A61M5/14566 ,  A61M2005/14553

Abstract: Syringes for use with medical fluid injectors. In certain aspects, the syringe includes a body having a longitudinal axis, a forward end, and a rearward end. At least one syringe mating section is coupled to the body of the syringe and is adapted to operatively engage an injector. In some embodiments, the syringe mating section includes first, second, and third flanges extending outwardly from the body along a plane substantially perpendicular to the longitudinal axis. In some embodiments, the syringe mating section includes a first flange having a cross-section of a parallelogram and a second flange having a tapered surface. In some embodiments, the syringe mating section includes a flange having an L-shaped cross-section. Other embodiments of the syringe mating section may include yet other appropriate designs.

Abstract translation: 用于医用液体注射器的注射器。 在某些方面，注射器包括具有纵向轴线，前端和后端的主体。 至少一个注射器配合部分联接到注射器的主体并且适于可操作地接合注射器。 在一些实施例中，注射器配合部分包括沿着基本上垂直于纵向轴线的平面从身体向外延伸的第一，第二和第三凸缘。 在一些实施例中，注射器配合部分包括具有平行四边形横截面的第一凸缘和具有锥形表面的第二凸缘。 在一些实施例中，注射器配合部分包括具有L形横截面的凸缘。 注射器配合部分的其它实施例可以包括其他合适的设计。

公开(公告)号：WO2008086004A1

公开(公告)日：2008-07-17

申请号：PCT/US2008/000312

申请日：2008-01-08

Applicant: MALLINCKRODT INC. ,  FAGO, Frank, M.

Inventor： FAGO, Frank, M.

IPC: A61M5/178 ,  A61M5/32 ,  G21F5/018

CPC classification number: A61M5/1785 ,  A61M5/3202 ,  A61M5/3204 ,  A61M2005/3215 ,  G21F5/018 ,  G21Y2002/501 ,  G21Y2004/30 ,  G21Y2004/40

Abstract: The invention relates to a radiation shielded syringe assembly that includes a radiopharmaceutical syringe and a radiation shield (101) disposed about at least a portion of the syringe. The radiation shield may include a needle cap ejector (155) to assist a user in removing a needle cap (125) from a needle of the syringe (e.g., to perform an injection). For instance, in some embodiments, the user may press/push the needle cap ejector to detach the needle cap from the needle of the syringe. The radiation shield and needle cap ejector may be designed such that the needle cap may be removed from the needle of the syringe while the user is shielded from undesired exposure to radiation emitted from the radiopharmaceutical within the syringe.

Abstract translation: 本发明涉及一种辐射屏蔽注射器组件，其包括放射性药物注射器和围绕注射器的至少一部分设置的辐射屏蔽（101）。 辐射屏蔽可以包括针帽喷射器（155），以帮助使用者从注射器的针头移除针帽（125）（例如进行注射）。 例如，在一些实施例中，用户可以按压/推动针帽喷射器以将针帽从注射器的针脱离。 辐射屏蔽和针帽喷射器可以被设计成使得当使用者被屏蔽以避免从注射器内的放射性药物发射的辐射的不期望的暴露时，针帽可以从针筒的针上移除。

公开(公告)号：WO2008076150A2

公开(公告)日：2008-06-26

申请号：PCT/US2007/015948

申请日：2007-07-12

Applicant: MALLINCKRODT INC. ,  BRUCE, John, K. ,  FAGO, Frank, M.

Inventor： BRUCE, John, K. ,  FAGO, Frank, M.

IPC: A61M5/178 ,  G21F5/018

CPC classification number: A61M5/1785 ,  A61M2005/312 ,  A61M2005/3128 ,  G21F5/018

Abstract: The invention relates to radiation shielding for use with radiopharmaceutical syringes. For example, in at least some regards, the invention relates to a syringe radiation shield that includes a sleeve having a syringe receptacle defined therein to accommodate a barrel of the syringe. In addition, this syringe radiation shield may also include a cover having a plunger receptacle defined therein to accommodate a plunger of the syringe. The sleeve and the cover may be removably coupled with one another so that the syringe can be housed within the syringe radiation shield, for example, during administration of a radiopharmaceutical from the syringe.

Abstract translation: 本发明涉及用于放射性药物注射器的辐射屏蔽。 例如，至少在某些方面，本发明涉及一种注射器辐射屏蔽，其包括具有限定在其中的注射器容器的套筒，以容纳针筒的筒体。 此外，该注射器辐射屏蔽还可以包括具有限定在其中的柱塞接收器的盖以容纳注射器的柱塞。 套筒和盖可以彼此可拆卸地联接，使得注射器可以容纳在注射器辐射屏蔽内，例如在从注射器施用放射性药物期间。

公开(公告)号：WO2008063529A1

公开(公告)日：2008-05-29

申请号：PCT/US2007/023967

申请日：2007-11-13

Applicant: MALLINCKRODT INC. ,  FAGO, Frank, M.

Inventor： FAGO, Frank, M.

IPC: A61M5/145

CPC classification number: A61M5/14546 ,  A61M5/14566 ,  A61M5/31515 ,  A61M2005/14553

Abstract: The invention relates to an adapter for a syringe plunger. The adapter of some embodiments may include a first side adapted to interface with a syringe plunger and an opposing a second side adapted to interface with a drive ram of a medical fluid injector. The adapter may include a peripheral side surface exhibiting a thickness and may include what may be characterized as at least one mating section adapted to engage with the syringe plunger. The mating section(s) may include a channel extending through the entire thickness of the adapter. In some embodiments, the mating section(s) may include a stop adjacent the channel that extends less than the entirety of the thickness of the adapter.

Abstract translation: 本发明涉及一种用于注射器柱塞的适配器。 一些实施例的适配器可以包括适于与针筒柱塞相接合的第一侧和适于与医用流体注射器的驱动柱塞相接合的相对的第二侧。 适配器可以包括表现出厚度的周边侧表面，并且可以包括可以被表征为适于与针筒柱塞接合的至少一个配合部分的外围侧表面。 配合部分可以包括延伸穿过适配器的整个厚度的通道。 在一些实施例中，配合部分可以包括邻近通道的止动件，该止动件小于适配器的整体厚度。

公开(公告)号：WO2006130681A3

公开(公告)日：2007-04-26

申请号：PCT/US2006021108

申请日：2006-05-31

Applicant: MALLINCKRODT INC ,  HYNES MICHAEL R ,  FAGO FRANK M

Inventor： HYNES MICHAEL R ,  FAGO FRANK M

IPC: A61M5/44

CPC classification number: A61M5/445 ,  A61M5/007 ,  A61M2205/3633

Abstract: The present invention relates to heat-retaining syringe jackets for reducing the cooling rate of medical fluids held inside syringes and methods of using such syringe jackets. An exemplary syringe jacket of the invention may include a material that experiences a phase transition at a phase transition temperature. Additionally or alternatively, the exemplary syringe jacket may include a material exhibiting a high specific heat.

Abstract translation: 本发明涉及用于降低保持在注射器内部的医疗液体的冷却速度的保温注射器护套和使用这种注射器护套的方法。 本发明的示例性注射器套管可以包括在相变温度下经历相变的材料。 另外或替代地，示例性注射器套管可以包括表现出高比热的材料。

公开(公告)号：WO2006124775A3

公开(公告)日：2007-04-12

申请号：PCT/US2006018727

申请日：2006-05-16

Applicant: MALLINCKRODT INC ,  WAGNER GARY S ,  FAGO FRANK M ,  GRISPO KEITH M ,  GIBSON CHAD M ,  LEWIS JOHN H ,  BAUSMITH WILLIAM E ,  HAYNES ELAINE E ,  WILSON DAVID W ,  ORTENZI VERNON D ,  BORGEMENKE ELAINE

Inventor： WAGNER GARY S ,  FAGO FRANK M ,  GRISPO KEITH M ,  GIBSON CHAD M ,  LEWIS JOHN H ,  BAUSMITH WILLIAM E ,  HAYNES ELAINE E ,  WILSON DAVID W ,  ORTENZI VERNON D ,  BORGEMENKE ELAINE

IPC: A61M5/178 ,  A61M5/145 ,  A61N5/10 ,  G01N23/10 ,  G01T7/02 ,  G21F5/015 ,  G21F5/018

CPC classification number: A61M5/14546 ,  A61M5/007 ,  A61M5/1456 ,  A61M5/16827 ,  A61M5/172 ,  A61M5/1785 ,  A61M2005/14506 ,  A61M2205/60 ,  A61M2205/6018 ,  G06K2017/009

Abstract: Certain embodiments of the invention relate to a radiopharmaceutical system having a shielded cordless injector and various radiopharmaceutical pig and syringe structures that permit the syringe to remain in the pig during transportation and use of the syringe. In some embodiments, the shielded cordless injector may include an injector, a radiation shield disposed at least partially about the injector, a drive coupled to the injector, and an energy storage device coupled to the drive. The pig may have a computer with a display screen that displays a radioactivity level of a radiopharmaceutical and/or a desired (e.g., correct) unit dose volume of a radiopharmaceutical to be administered to a patient.

Abstract translation: 本发明的某些实施例涉及具有屏蔽无绳注射器和各种放射性药物猪和注射器结构的放射性药物系统，其允许注射器在注射器的运输和使用期间保持在猪中。 在一些实施例中，屏蔽无绳注射器可以包括注射器，至少部分地围绕注射器设置的辐射屏蔽，耦合到注射器的驱动器以及耦合到驱动器的能量存储装置。 猪可以具有显示屏幕的计算机，其显示放射性药物的放射性水平和/或待给予患者的放射性药物的期望（例如，正确的）单位剂量体积。