Abstract:
The present invention relates to a continuous process for conducting a chemical reaction in a liquid reaction medium. Characteristically: - said continuous process is carried out in a microreactor (10), - said chemical reaction produces a solid insoluble in said liquid reaction medium, and - said continuous process comprises the continuous extraction of said solid, as it is produced, with a solvent S2, immiscible with said reaction medium. Such a process is advantageously carried out for conducting the activation of a carboxylic acid in the presence of an organic base.
Abstract:
A fluidics apparatus is disclosed for manipulation of at least one fluid sample, typically in the form of a droplet. The apparatus has a substrate surface with a sample manipulation zone for location of the fluid sample. A transducer arrangement such as an interdigitated electrode structure on a piezoelectric body provides surface acoustic waves at the substrate surface for manipulation of the fluid sample. The substrate surface has an arrangement of surface acoustic wave scattering elements forming a phononic crystal structure for affecting the transmission, distribution and/or behaviour of surface acoustic waves at the substrate surface. Also disclosed is a method for lysing a cell. In this method, the cell is comprised in a fluid sample contacting a substrate surface, the method comprising providing surface acoustic waves at the substrate surface, such that the cell lyses.
Abstract:
Die Erfindung betrifft einen mikrofluidischen Reaktor mit einem als Ringkanal (22) ausgebildeten Reaktionsraum. Erfindungsgemäß ist vorgesehen, dass in dem Ringkanal (22) Segmente (25) dadurch gebildet sind, dass durch eine Abfolge von Einlassen (23) und Auslässen (24) ein Wechsel zwischen den Prozessfluiden (A und B) stattfinden kann. In dem Ringkanal (22) können erfindungsgemäß weiter Partikel (27) vorgesehen sein, die in dem Ringkanal umlaufen und beispielsweise zur Adsorption und Desorption von Ionen verwendet werden können. Auf diese Weise können die betreffenden Ionen beispielsweise aus dem Prozessfluid (A) abgezogen und in das Prozessfluid (B) übertragen werden. Der erfindungsgemäße Reaktor kann in einem weiterhin beanspruchten Verfahren beispielsweise dazu verwendet werden, 18 F - -Ionen aus mit diesem angereicherten Wasser zu gewinnen und einem Lösemittel wie Acetonitril zuzuführen. Im weiteren Verlauf kann mit den 18 F - -Ionen ein Radiopharmakon (beispielsweise FDG) hergestellt werden.
Abstract:
A microchannel apparatus comprising a conduit including a microchannel mixing section, a microchannel reaction section, a microchannel heat transfer section, and a separation section, where the microchannel mixing section includes direct injection inlets, where the microchannel mixing section is downstream from the reaction section, and where the separation section is downstream from the reaction section. Further exemplary embodiments are also disclosed.
Abstract:
The invention described herein concerns microchannel apparatus that contains, within the same device, at least one manifold and multiple connecting microchannels that connect with the manifold. For superior heat or mass flux in the device, the volume of the connecting microchannels should exceed the volume of manifold or manifolds. Methods of conducting unit operations in microchannel devices having simultaneous disrupted and non-disrupted flow through microchannels is also described.
Abstract:
The invention provides for the utilisation of microchannel apparatus in a process for removing combustible, volatile contaminants from a process stream which comprises heating the process stream to the combustion temperature of the volatile contaminant materials and combusting the materials to form a hot cleaned stream also containing combustion products. The hot cleaned stream is conducted through heat exchange channels which are in thermal contact with the first set of process microchannels. The cooled, cleaned stream is then recovered. The microchannels may contain a catalyst for catalytic oxidation. The treated process stream may be a C02 waste stream from an ethylene oxide production plant.
Abstract:
The invention provides a process for the mixing of an oxidant having explosive potential with a hydrocarbon material, which comprises conveying a first stream comprising the hydrocarbon material and a second stream comprising the oxidant into a microchannel apparatus, allowing mixing to occur, and withdrawing the mixture. The microchannels have an internal height and/or width in the range of 0,5-1,5 mm. The process is useful for the preparation of ethylene oxide, where the microchannel apparatus is located in the recycle gas loop.
Abstract:
The invention describes microchannel apparatus and catalysts that contain a layer of a metal aluminide or are made in a process in which a metal aluminide layer is formed as an intermediate. Certain processing conditions have surprisingly been found to result in superior coatings. The invention includes chemical processes conducted through apparatus described in the specification. Other catalysts and catalyst synthesis techniques are also described.
Abstract:
The invention describes microchannel apparatus and catalysts that contain a layer of a metal aluminide or are made in a process in which a metal aluminide layer is formed as an intermediate. Certain processing conditions have surprisingly been found to result in superior coatings. The invention includes chemical processes conducted through apparatus described in the specification. Other catalysts and catalyst synthesis techniques are also described.