摘要:
La présente invention se rapporte à un système (1) de projection de particules (P) sur un substrat (22), comprenant : - au moins un réacteur (2) comportant au moins une entrée de réactifs liquides (R1, R2), une zone de réaction (14), ainsi qu'une zone (18) de collecte des particules (P) produites à partir des réactifs liquides dans la zone de réaction; - un dispositif de dispense (21) permettant de projeter les particules (P) sur le substrat (22); et - des moyens (26) d'acheminement des particules (P) de la zone de collecte (18) vers ledit dispositif de dispense (21).
摘要:
A flow reactor fluidic module (12) includes a reactant fluid module (20) having an internal process fluid passage (22) and a first major planar outer surface (24a) and a thermal resistance R between the internal process fluid passage (22) and the first major planar surface (24); a thermal control fluid module (30) having an internal thermal control fluid passage (32) and a second major planar outer surface (34a); a holding structure (50) holding the reactant fluid module (20) and the thermal control fluid module (30); and a gap (25) separating the first major planar surface (24a) from the second major planar surface (34a). The gap (25) comprises an interchangeable or replaceable substance or sheet (26) having a thermal resistance G across the gap (25), wherein G is not equal to R.
摘要:
The present invention provides a system for the production of a radiopharmaceutical including a radiosynthesis apparatus and a disposable cassette. The system of the invention includes a device that enables a position on the cassette to be freed for inclusion of an additional reagent vial. With the system of the invention a broader range of radiochemical syntheses can be envisaged using the cassette.
摘要:
Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
摘要:
The invention relates to a pressure sensor (100) for a measuring system (10) for measuring the concentration of gaseous and/or aerosol-like component of a gas mixture by using a reaction carrier (14) which has at least one flow channel (42), wherein the flow channel (42) forms a reaction chamber (46) having a reaction material (48) which is designed to enter into an optically detectable reaction with at least one component of the gas mixture that is to be measured or a reaction product of the component to be measured, and a measuring device (12), which comprises a gas connection sub-assembly (5) for the connection of a gas feed channel (16) and a gas discharge channel (18) to the flow channel (42) of the reaction carrier, and a gas conveying device (28) for conveying the gas mixture through the flow channel (42) of the reaction carrier (14). The pressure sensor (100) is designed to measure a pressure difference of a gas mixture flowing through the gas conveying sub-assembly (5) and/or flow channel (42) of the reaction carrier (14), and has an elastic element (102) which is designed to deform as a function of the pressure difference. The invention further relates to a measuring method, a measuring device and a reaction carrier for such a measuring system.
摘要:
The present invention generally relates to microfluidics, and, in particular, to systems and methods for coalescing or fusing droplets. In certain aspects, two or more droplets within a microfluidic channel are brought together and caused to coalesce without using electric fields or charges. For example, in certain embodiments, droplets stabilized with a surfactant may be disrupted, e.g., by exposing the droplets to a solvent able to alter the surfactant, which may partially destabilize the droplets and allow them to coalesce. In some instances, the droplets may also be physically disrupted to facilitate coalesce. In addition, in some cases, the positions of one or more droplets may be controlled within a channel using a groove in a wall of the channel. For example, a droplet may at least partially enter the groove such that the position of the droplet is at least partially controlled by the groove. In this way, droplets can be brought together within a channel, e.g., to cause coalescence of the droplets. Other aspects of the present invention are generally directed to devices containing such microfluidic channels or for performing such methods, methods of preparing such devices, kits including such devices, or the like.
摘要:
Die Erfindung betrifft einen Drucksensor (100) für ein Messsystem (10) zur Messung einer Konzentration von gas- und/oder aerosolförmigen Komponenten eines Gasgemisches mit einem Reaktionsträger (14), der zumindest einen Strömungskanal (42) aufweist, wobei der Strömungskanal (42) eine Reaktionskammer (46) mit einem Reaktionsstoff (48) bildet, welcher ausgebildet ist, um mit zumindest einer zu messenden Komponente des Gasgemisches oder einem Reaktionsprodukt der zu messenden Komponente eine optisch detektierbare Reaktion einzugehen, und einer Messvorrichtung (12), die eine Gasanschlussbaugruppe (5) zum Anschluss eines Gaszuflusskanals (16) und eines Gasabflusskanals (18) an den Strömungskanal (42) des Reaktionsträgers und eine Gasfördereinrichtung (28) zur Förderung des Gasgemisches durch den Strömungskanal (42) des Reaktionsträgers (14) umfasst. Der Drucksensor (100) ist ausgebildet, um eine Druckdifferenz eines durch die Gasförderbaugruppe (5) und/oder Strömungskanal (42) des Reaktionsträgers (14) strömenden Gasgemisches zu messen und ein elastisches Element (102) aufweist, welches ausgebildet ist, um sich in Abhängigkeit der Druckdifferenz zu verformen. Die Erfindung betrifft ferner ein Messverfahren, eine Messvorrichtung und einen Reaktionsträger für ein derartiges Messsystem.