LOCATING ABLATED TISSUES USING ELECTRIC PROPERTIES TOMOGRAPHY

    公开(公告)号:WO2018172195A1

    公开(公告)日:2018-09-27

    申请号:PCT/EP2018/056617

    申请日:2018-03-16

    Abstract: The invention provides for a medical system (100, 300, 400, 500) comprising: a memory (110) for storing machine executable instructions (150) and a processor (104) for controlling the medical system. Execution of the machine executable instructions cause the processor to: receive (200) first electric properties tomography data (152) descriptive of a first spatially dependent mapping (166) of an RF electrical property within a region of interest (310) of a subject (318), wherein the RF electrical property is a real valued permittivity or real valued conductivity; receive (202) second electric properties tomography data (154) descriptive of a second spatially dependent mapping (168) of the spatially dependent RF electrical property within the region of interest of the subject; calculate (204) a change (160) in the spatially dependent RF electrical property derived from a difference between the first electric properties tomography data and the second electric properties tomography data; and calculate (206) a spatially dependent ablation map (164) by indicating regions within the region of interest where the change in the spatially dependent RF electrical property is above a predetermined threshold.

    MEDICAL IMAGING SYSTEM COMPRISING A MAGNET UNIT AND A RADIATION UNIT

    公开(公告)号:WO2018095587A1

    公开(公告)日:2018-05-31

    申请号:PCT/EP2017/059690

    申请日:2017-04-25

    Abstract: The invention relates to a medical imaging system comprising a magnet unit (20) embodied for magnetic resonance imaging of an examination object and a first radiation unit (30) embodied to irradiate the examination object, wherein the magnet unit comprises a main magnet and a first housing, wherein the main magnet is arranged inside the first housing and wherein the main magnet comprises coil elements and at least one coil carrier. The magnet unit furthermore defines an examination opening (90) along an examination axis such that the magnet unit surrounds the examination opening. The magnet unit furthermore comprises a first region that is transparent to radiation from the first radiation unit emitted radially to the examination axis. The first radiation unit is furthermore arranged on the side of the magnet unit facing away from the examination opening and embodied to emit radiation through the first region of the magnet unit in the direction of the examination opening. The first radiation unit is furthermore embodied to rotate about the examination opening.

    IMPROVEMENT OF SIMULTANEOUS MEASURE OF THE TEMPERATURE AND THE DISPLACEMENT MEASURED WITH MAGNETIC RESONANCE ACOUSTIC RADIATION FORCE IMAGING
    45.
    发明申请
    IMPROVEMENT OF SIMULTANEOUS MEASURE OF THE TEMPERATURE AND THE DISPLACEMENT MEASURED WITH MAGNETIC RESONANCE ACOUSTIC RADIATION FORCE IMAGING 审中-公开
    磁共振声辐射力成像测量温度的同时测量和位移的改进

    公开(公告)号:WO2018065245A1

    公开(公告)日:2018-04-12

    申请号:PCT/EP2017/074153

    申请日:2017-09-25

    Abstract: In Magnetic Resonance Acoustic Radiation Force Imaging (MR-ARFI), an MR imaging device (10) performs gradient echo imaging including successive MR dynamics with opposite encoding of displacement to generate MR-ARFI data of a subject comprising successive image frames with opposite displacement encoding. An ultrasound device (12) applies sonication to the subject during the gradient echo imaging. An electronic processor (22) performs MR-ARFI data processing applied to image elements at image frames of the MR-ARFI data. A displacement is computed (30) for the image element at the image frame as proportional to a phase difference between the image element in the image frame and the image element in a succeeding or preceding image frame with opposite displacement encoding. The computed displacement is corrected (32) for a temperature change between the image frame and the succeeding or preceding image frame. The temperature change is determined using the MR-ARFI data.

    Abstract translation: 在磁共振声辐射力成像(MR-ARFI)中,MR成像设备(10)执行梯度回波成像,包括具有相反位移编码的连续MR动态变化以生成受试者的MR-ARFI数据 包括具有相反位移编码的连续图像帧。 超声装置(12)在梯度回波成像期间对受试者应用超声处理。 电子处理器(22)执行应用于MR-ARFI数据的图像帧处的图像元素的MR-ARFI数据处理。 计算(30)图像帧处的图像元素的位移,其与图像帧中的图像元素与具有相反位移编码的后续或前一图像帧中的图像元素之间的相位差成比例。 计算出的位移对图像帧与后续或前面的图像帧之间的温度变化进行校正(32)。 温度变化是使用MR-ARFI数据确定的。

    SYSTEMS AND METHODS FOR MODELING NEURAL ARCHITECTURE
    46.
    发明申请
    SYSTEMS AND METHODS FOR MODELING NEURAL ARCHITECTURE 审中-公开
    用于建模神经结构的系统和方法

    公开(公告)号:WO2018052987A1

    公开(公告)日:2018-03-22

    申请号:PCT/US2017/051343

    申请日:2017-09-13

    Abstract: Systems and methods are described herein for modeling neural architecture. Regions of interest of a brain of a subject can be identified based on image data characterizing the brain of the subject. The identified regions of interest can be mapped to a connectivity matrix. The connectivity matrix can be a weighted and undirected network. A multivariate transformation can be applied to the connectivity matrix to transform the connectivity matrix into a partial correlation matrix. The multivariate transformation can maintain a positive definite constraint for the connectivity matrix. The partial correlation matrix can be transformed into a neural model indicative of the connectivity matrix.

    Abstract translation: 这里描述了用于建模神经架构的系统和方法。 可以基于表征受试者的大脑的图像数据来识别受试者的大脑的感兴趣区域。 所标识的感兴趣区域可以被映射到连通性矩阵。 连接矩阵可以是加权和无向网络。 多元变换可应用于连通性矩阵,以将连通性矩阵变换为偏相关矩阵。 多变量变换可以保持连通矩阵的正定约束。 偏相关矩阵可以转化为表示连通矩阵的神经模型。

    RAPID DETERMINATION OF A RELAXATION TIME
    47.
    发明申请
    RAPID DETERMINATION OF A RELAXATION TIME 审中-公开
    快速确定放松时间

    公开(公告)号:WO2017210226A1

    公开(公告)日:2017-12-07

    申请号:PCT/US2017/035073

    申请日:2017-05-30

    Applicant: Q BIO, INC.

    Abstract: During operation, a system may apply a polarizing field and an excitation sequence to a sample. Then, the system may measure a signal associated with the sample for a time duration that is less than a magnitude of a relaxation time associated with the sample. Next, the system may calculate the relaxation time based on a difference between the measured signal and a predicted signal of the sample, where the predicted signal is based on a forward model, the polarizing field and the excitation sequence. After modifying at least one of the polarizing field and the excitation sequence, the aforementioned operations may be repeated until a magnitude of the difference is less than a convergence criterion. Note that the calculations may be performed concurrently with the measurements and may not involve performing a Fourier transform on the measured signal.

    Abstract translation: 在操作期间,系统可以将偏振场和激励序列应用于样本。 然后,系统可以测量与样本相关的信号的持续时间小于与样本相关联的弛豫时间的量值。 接下来,系统可基于测量信号与样本的预测信号之间的差异来计算弛豫时间,其中预测信号基于正向模型,极化场和激励序列。 在修改极化场和激励序列中的至少一个之后,可以重复上述操作,直到差值的量值小于收敛标准。 请注意,计算可能与测量同时执行,可能不涉及对测量信号执行傅立叶变换。

    SYNTHETIC COMPUTED TOMOGRAPHY IMAGING
    49.
    发明申请
    SYNTHETIC COMPUTED TOMOGRAPHY IMAGING 审中-公开
    综合计算机断层摄影成像

    公开(公告)号:WO2017153122A1

    公开(公告)日:2017-09-14

    申请号:PCT/EP2017/053008

    申请日:2017-02-10

    Inventor: WEISS, Steffen

    Abstract: The invention provides for a computer program product for calculating synthetic CT image (124). The computer program product comprises machine executable instructions (130) for execution by a processor (104). Execution of the machine executable instructions causes the processor to: receive (200) bone mineralization density data (114); receive (202) a magnetic resonance image (116) of a region of interest (309); calculate (204) an image segmentation (118) by segmenting the magnetic resonance image into a set of tissue types, wherein the set of tissue types comprises a cortical bone segmentation; calculate (206) a cortical bone Hounsfield value (120) using the bone mineralization density data; calculate (208) a Hounsfield unit mapping (122) by assigning at least one Hounsfield unit value to each of the set of tissue types in the image segmentation, wherein the cortical bone segmentation is assigned the cortical bone Hounsfield value; and calculate (210) the synthetic CT image using the Hounsfield unit mapping.

    Abstract translation: 本发明提供了用于计算合成CT图像的计算机程序产品(124)。 该计算机程序产品包括由处理器(104)执行的机器可执行指令(130)。 机器可执行指令的执行使得处理器:接收(200)骨矿化密度数据(114); 接收(202)感兴趣区域(309)的磁共振图像(116); 通过将所述磁共振图像分割成一组组织类型来计算(204)图像分割(118),其中所述一组组织类型包括皮质骨分割; 使用所述骨矿化密度数据计算(206)皮质骨Hounsfield值(120); 通过将至少一个亨氏单位值分配给图像分割中的每组组织类型来计算(208)亨氏单位映射(122),其中皮质骨分割被指定为皮质骨Hounsfield值; 并使用Hounsfield单位映射计算(210)合成CT图像。

    METHODS AND SYSTEMS FOR CORRECTING K-SPACE TRAJECTORIES
    50.
    发明申请
    METHODS AND SYSTEMS FOR CORRECTING K-SPACE TRAJECTORIES 审中-公开
    用于校正K空间轨迹的方法和系统

    公开(公告)号:WO2017119994A1

    公开(公告)日:2017-07-13

    申请号:PCT/US2016/066361

    申请日:2016-12-13

    CPC classification number: G01R33/4818 G01R33/243 G01R33/56518 G01R33/58

    Abstract: Various methods and systems are provided for correcting k-space trajectories. In one embodiment, a system comprises a coil configured to generate a magnetic field, a plurality of magnetic field probes positioned at the coil and configured to measure the magnetic field, and a controller communicatively coupled to the plurality of magnetic field probes and including instructions stored in non-transitory memory that when executed cause the controller to: receive measurements of the magnetic field from the plurality of magnetic field probes; calculate corrections to positions of acquired magnetic resonance signals in spatial-frequency space based on the received measurements; apply the corrections to the positions to generate corrected magnetic resonance signals; and reconstruct an image from the corrected magnetic resonance signals. In this way, image artifacts caused by eddy currents can be reduced.

    Abstract translation: 提供了用于修正k空间轨迹的各种方法和系统。 在一个实施例中,系统包括被配置为产生磁场的线圈,被定位在线圈处并被配置为测量磁场的多个磁场探测器,以及被通信地耦合到多个磁场探测器并包括存储的指令的控制器 在非暂时性存储器中,所述非暂时性存储器在被执行时使所述控制器:接收来自所述多个磁场探针的所述磁场的测量结果; 基于接收到的测量值计算对所采集的磁共振信号在空间频率空间中的位置的校正; 将校正应用于位置以生成校正的磁共振信号; 并从修正的磁共振信号重建图像。 通过这种方式,可以减少由涡流引起的图像伪影。

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