LIGHT-SHEET PHOTONIC-FORCE OPTICAL COHERENCE ELASTOGRAPHY

    公开(公告)号:WO2021155382A1

    公开(公告)日:2021-08-05

    申请号:PCT/US2021/016110

    申请日:2021-02-01

    Abstract: Disclosed are devices and techniques based on optical coherence tomography (OCT) technology in combination with optical actuation. A system for providing optical actuation and optical sensing can include an optical coherence tomography (OCT) device that performs optical imaging of a sample based on optical interferometry from an optical sampling beam interacting with an optical sample and an optical reference beam; an OCT light source to provide an OCT imaging beam into the OCT device which splits the OCT imaging beam into the optical sampling beam and the optical reference beam; and a light source that produces an optical actuation beam that is coupled along with the optical sampling beam to be directed to the sample to actuate particles or structures in the sample so that the optical imaging captures information of the sample under the optical actuation.

    BACK-CONVERSION SUPPRESSED OPTICAL PARAMETRIC AMPLIFICATION

    公开(公告)号:WO2021067969A1

    公开(公告)日:2021-04-08

    申请号:PCT/US2020/054317

    申请日:2020-10-05

    Abstract: In one aspect, a device is disclosed that includes one or more input ports structured to receive a pumping light at a pumping wavelength and a signal light at a signal wavelength, and one or more output ports structured to output light including an amplified signal light at the signal wavelength and a second harmonic idler light. The device includes a nonlinear optical material to mix the pumping light and the signal light and to cause nonlinear conversion of the pumping light into the amplified signal light and generate an idler light at an idler wavelength. The nonlinear optical material is further structured to convert the idler light into the second harmonic idler light which eliminates the idler light at the one or more output ports and prevents back-conversion of the amplified signal light and idler light to the pumping wavelength.

    OPTICAL RELAY STATION-BASED IMPLANTABLE SENSOR MODULES

    公开(公告)号:WO2020214743A1

    公开(公告)日:2020-10-22

    申请号:PCT/US2020/028374

    申请日:2020-04-15

    Abstract: The technology disclosed can be implemented to construct devices with an array of optical elements to provide power to stimulate a biological process in a nerve system in living objects, and to provide patterned light outputs from the array of optical elements to indicate a corresponding electrical pattern monitored from the biological process in the nerve system. In one aspect a nerve stimulator apparatus is disclosed including a plurality of optical to electrical transducers arranged in a two-dimensional array, wherein each of the plurality of optical to electrical transducers is configured to convert light to an electrical signal; a plurality of electrodes, each electrode associated with one or more associated optical to electrical transducers; and a plurality of electrical interconnects to connect each of the plurality of electrodes to the one or more associated optical transducers. In another aspect nerve sensor apparatus is disclosed including a plurality of optical to electrical transducers; a plurality of optical sources; a plurality of electrodes, each electrode associated with one or more optical to electrical transducers, each optical source configured to modulate light output according to a voltage at one of the plurality of electrodes; and a plurality of electrical interconnects.

    SCANNING MICROSCOPE WITH MULTIPLEXED LIGHT SOURCES

    公开(公告)号:WO2019204820A1

    公开(公告)日:2019-10-24

    申请号:PCT/US2019/028562

    申请日:2019-04-22

    Applicant: COLUXA INC.

    Inventor: XU, Heng

    Abstract: A scanning microscope multiplexes illumination light beams at different optical wavelengths (e.g., from different light sources) by placing illumination light beams non-coaxially to create separate focuses at specimen. Reflected or fluorescent light generated by the different illumination light beams is recorded simultaneously while scanning the specimen.

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