Abstract:
The present invention includes compositions and methods for the treatment, diagnosis and prognosis of cancers by detecting the level of IL- 13 expression in cancerous cells in the tissue microenvironment as an indicator of controlling the type of immune response mounted against the cancer.
Abstract:
The present invention includes compositions, methods, systems and kits for the controlled delivery of an active agent within a polymeric network upon the binding of a molecule that decreases the structural integrity of the polymeric network at one or more micro- or nano vacuoles.
Abstract:
The present invention includes an apparatus and method for producing x-rays (38), and/or ion beams and for enabling the generation of fusion energy and the conversion of the energy into electrical energy including an anode (14) and a cathode (12) positioned coaxially and at least partially within a reaction chamber that imparts an angular momentum to a plasmoid. The angular momentum may be imparted through the cathode (12) having a helical twist; a helical coil (22), about the cathode (12) or a combination thereof. The anode (14) has an anode radius and the cathode (12) has a cathode radius that imparts a high magnetic field. The reaction chamber contains a gas and an electronic discharge source in electrical communication with the anode (14) and the cathode (12). As a result of an electronic discharge a dense, magnetically confined, plasmoid is created about the anode (14) and emits of one or more particles.
Abstract:
The present invention includes compositions and methods for treating skin conditions, and more particularly, a medicinal progression of anti-oxy-vitamins to treat one or more skin conditions in a patient selected from at least one of acne, skin discoloration, comedo presence, foci of inflammation, hyper-keratinosis, enlarged sebum vessels, pores enlargement, scars or piling centers.
Abstract:
The present invention provides a membrane, kit, and method of making a hydrophilic- hydrophobic random copolymer membrane. The hydrophilic-hydrophobic random copolymer membrane includes a hydrophilic-hydrophobic random copolymer. The hydrophilic-hydrophobic random copolymer includes one or more hydrophilic monomers having a sulfonated polyarylsulfone monomer and a second monomer and one or more hydrophobic monomers having a non-sulfonated third monomer and a fourth monomer. The sulfonated polyarylsulfone monomer introduces a sulfonate into the hydrophilic- hydrophobic random copolymer prior to polymerization.
Abstract:
The present invention includes a model system and use of the same for the study, manipulation and focusing of the human immune in a mammal, e.g., a nonhuman mammal that is immune deficient with one or more human hematopoietic progenitor cells and one or more human tumor cell lines.
Abstract:
The present invention includes compositions, systems and methods for the early detection and consistent determination of systemic onset juvenile idiopathic arthritis (SoJIA) usin microarrays.
Abstract:
The present invention includes compositions and method of treating a textile with an antimicrobial agent, the method comprising contacting the textile with an antimicrobial agent that comprises a reactive dye or crosslinking agent comprising an organo-selenium compound in a treatment solution.
Abstract:
The present invention includes methods of making, compositions, or vaccinations comprising a recombinant vesicular stomatitis vims (rVSV) viral vector that expresses a Nipah Virus protein antigen, wherein the rVSV vector comprises one or more heterologous polynucleotides coding for and expressing a Nipah Virus NiVB G-protein antigen; wherein the NiVB G-protein comprises an amino acid sequence as set forth in SEQ ID NO: 6, or wherein the heterologous polynucleotide encodes a. polypeptide coding for the NiVB G-protein antigen comprising at least 90% sequence identity to an amino acid sequence as set forth in SEQ ID NO: 6, or 90% sequence identity to a nucleic acid sequence as set forth in SEQ ID NO: 2, wherein the composition or vaccine is effective to reduce or prevent a Nipah Virus infection at 3 days.
Abstract:
The present invention includes a compositions and methods comprising: one or more thyroid hormones in or on a micro-multi-particulate having a mean particle size of 150 uM or smaller and a Span (D90-D10)/(D50) of less than 2.0, wherein the total thyroid hormone(s) are less than 10% weight-to-weight (w/w) of the micro-multi-particulate; and a polymer release coating on the micro-multi-particulate that is greater than a 5: 1 ratio w/w, on a dry weight basis, to a dry weight of the thyroid hormone(s), wherein a total tablet weight exceeds a micro-multi-particulate weight by a ratio of 5: 1 or greater.