公开(公告)号：WO2004100800A2

公开(公告)日：2004-11-25

申请号：PCT/US2004/009843

申请日：2004-03-31

Applicant: MEDTRONIC, INC. ,  ROTHSTEIN, Paul, T. ,  PIGNATO, Paul, A. ,  DAIGLE, Thomas, P. ,  GOODMAN, Jack

Inventor： ROTHSTEIN, Paul, T. ,  PIGNATO, Paul, A. ,  DAIGLE, Thomas, P. ,  GOODMAN, Jack

IPC: A61B17/04

CPC classification number: A61B17/06061 ,  A61B17/0483 ,  A61B90/50 ,  A61B2017/0237

Abstract: A device for holding a surgical suture including a base, a guide body, a cam body, a bearing member, and a spring member. The base has a top side, a front edge, and a back edge. The guide body projects from the top side of the base and defines a guide face having an entrance side and an exit side. The entrance side is adjacent the front edge and the exit side is adjacent the back edge. The cam body is pivotally mounted to the top side and forms a toothed surface positioned to selectively secure a surgical suture against the guide face. The spring member is positioned between the cam body and the bearing member, biasing the toothed surface toward the guide face.

Abstract translation: 一种用于保持包括基部，引导体，凸轮体，支承构件和弹簧构件的手术缝合线的装置。 底座具有顶侧，前边缘和后边缘。 引导体从基部的顶侧突出并且限定具有入口侧和出口侧的引导面。 入口侧邻近前缘，出口侧邻近后缘。 凸轮主体枢转地安装到顶侧并形成齿形表面，其被定位成选择性地将外科缝合线固定抵靠引导面。 弹簧构件定位在凸轮本体和轴承构件之间，将齿形表面朝向引导面偏置。

公开(公告)号：WO2004096070A1

公开(公告)日：2004-11-11

申请号：PCT/US2004/012270

申请日：2004-04-20

Applicant: MEDTRONIC, INC. ,  BRISCOE, Roderick, E.

Inventor： BRISCOE, Roderick, E.

IPC: A61B18/14

CPC classification number: A61B18/1492 ,  A61B18/16 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00351

Abstract: Methods and devices for forming a lesion in a target tissue having a cavity within. A first RF electrode and a second RF electrode can be coupled to opposite poles of an RF current source. The second electrode can be inserted into the tissue cavity and expanded to contact the target tissue from within. The first electrode can be externally disposed against the target tissue while applying RF current between the first and second electrodes to ablate the target tissue. Some methods are directed to ablating tribiculated atrial wall tissue to treat atrial fibrillation. The second electrode can contact the tribiculated tissue directly from within to provide a direct path between the two electrodes. In some methods, the second electrode is inserted through an incision made to remove an atrial appendage. The methods can provide deeper, narrower lesions relative to those made using remote, indifferent electrodes. Atrial fibrillation ablation procedures can be performed using the invention, requiring fewer incisions than conventional methods.

Abstract translation: 在具有腔内的靶组织中形成病变的方法和装置。 第一RF电极和第二RF电极可以耦合到RF电流源的相对极。 第二电极可以插入到组织腔中并膨胀以从内部接触靶组织。 第一电极可以在外部设置在靶组织上，同时在第一和第二电极之间施加RF电流以烧蚀靶组织。 一些方法是针对消融多发性心房壁组织以治疗房颤。 第二电极可以直接从内部接触多形性组织以提供两个电极之间的直接路径。 在一些方法中，第二电极通过切口插入以除去心耳。 相对于使用远程，无关电极的方法，这些方法可以提供更深，更窄的病变。 可以使用本发明进行心房颤动消融手术，比常规方法需要更少的切口。

公开(公告)号：WO2003106040A3

公开(公告)日：2003-12-24

申请号：PCT/US2003/018527

申请日：2003-06-12

Applicant: MEDTRONIC, INC.

Inventor： DOLECK, Victor, D. ,  MERTE, Kenneth, E. ,  MCINTOSH, Kevin, D. ,  BERG, Gary ,  MALCOLM, David ,  SITKO, Vitally, G.

IPC: B04B5/04

Abstract: A centrifugal method, and corresponding system, for processing blood to collect platelet rich plasma. A separation chamber is filled with blood from a fill syringe by rotating the separation chamber at fill rotation rate and pumping the blood from the fill syringe. A soft spin is used to initially separate red blood cells from platelets by spinning the separation chamber at a soft spin rate. A percentage of the blood is drawn from the separation chamber back into the fill syringe to remove separated red blood cells. A second portion of the separated blood is drawn from the separation chamber until a red blood cell/platelet interface is detected. A hard spin is performed by spinning the separation chamber at a higher rate and connecting tubing is cleared of red blood cells by drawing a predetermined clearing volume. The platelet rich plasma is then collected in the collection syringe.

公开(公告)号：WO2003063717A1

公开(公告)日：2003-08-07

申请号：PCT/US2003/001036

申请日：2003-01-14

Applicant: MEDTRONIC,INC.

Inventor： FRANCISCHELLI, David, E. ,  MEHRA, Rahul ,  LUTTERMAN, Alison

IPC: A61B18/14

CPC classification number: A61B18/1492 ,  A61B2018/00029 ,  A61B2018/00351 ,  A61B2018/00363 ,  A61B2018/00577 ,  A61B2018/00738 ,  A61B2018/1253 ,  A61B2018/1472

Abstract: A system and method of making a lesion on living tissue including providing an electrosurgical system, determining a desired lesion depth, selecting a power setting, and applying electrical energy to the living tissue. The system includes an instrument having an electrode at a distal portion thereof, and a power source having multiple available power settings. The power source is electrically connected to the electrode. The step of applying electrical energy includes energizing the electrode at the selected power setting for a recommended energization time period that is determined by reference to predetermined length of time information and based upon the desired lesion depth and the selected power setting. The system preferably further includes a fluid source for irrigating the electrode at an irrigation rate. In this regard, the predetermined length of time information is generated as a function of irrigation rate.

Abstract translation: 一种在活体组织上形成损伤的系统和方法，包括提供电外科系统，确定期望的病变深度，选择功率设定以及向生物体组织施加电能。 该系统包括在其远端部分具有电极的仪器和具有多个可用功率设置的电源。 电源电连接到电极。 施加电能的步骤包括以所选择的功率设置激励电极，以建立通电时间段，该推荐通电时间周期参考预定时间长度信息确定，并且基于期望的病变深度和所选择的功率设置。 该系统优选地还包括用于以灌溉速率冲洗电极的流体源。 在这方面，根据灌溉速率产生预定长度的时间信息。

公开(公告)号：WO2002080991A2

公开(公告)日：2002-10-17

申请号：PCT/US2002/010989

申请日：2002-04-05

Applicant: MEDTRONIC, INC.

Inventor： BAUGH, Robert, F. ,  LIM, Lisa, M. ,  JOHNSTON, Julie, S. ,  RIVERIA, John, G. ,  DOLECK, Victor, D. ,  MCKAY, William, F. ,  MARX, Jeffery, C.

IPC: A61L24/10

CPC classification number: A61L24/0005 ,  A61L26/0057 ,  A61M1/3633 ,  A61M1/3693 ,  A61M1/3696 ,  A61M2202/0415 ,  A61M2202/0427 ,  A61M2205/331

Abstract: A centrifuge system for the formation of an autologous platelet gel wherein all of the blood components for the gel are derived from a patient to whom the gel is to be applied. First a platelet rich plasma and a platelet poor plasma are formed by centrifuging a quantity of anticoagulated whole blood that was previously drawn from the patient. The platelet rich plasma or platelet poor plasma is then automatically drawn out of the centrifuge bag and proportioned into separate chambers in a dispenser. The first portion is activated where a clot is formed and thrombin is obtained. The thrombin is then latter mixed with the second portion to obtain a platelet gel.

Abstract translation: 公开了一种用于形成自体血小板凝胶的离心机系统，其中所述凝胶的所有血液成分源于要施用凝胶的患者。 首先通过离心一定数量的抗凝血全血形成血小板富血浆和血小板不良血浆，这是先前从患者中抽出的。 然后将富含血小板的血浆或血小板不良等离子体自动从离心机中抽出并在分配器中成比例分成不同的室。 在形成凝块并获得凝血酶的情况下，第一部分被激活。 然后将凝血酶与第二部分混合以获得血小板凝胶。 交货系统被提及。

公开(公告)号：WO2005034782A2

公开(公告)日：2005-04-21

申请号：PCT/US2003/015549

申请日：2003-05-15

Applicant: MEDTRONIC, INC.

Inventor： FRANCISCHELLI, David, E.

IPC: A61B18/00

CPC classification number: A61B18/1477 ,  A61B2018/00809 ,  A61B2018/1472 ,  A61B2090/395

公开(公告)号：WO2004064647A1

公开(公告)日：2004-08-05

申请号：PCT/US2004/000597

申请日：2004-01-09

Applicant: MEDTRONIC, INC.

Inventor： BONNER, Matthew, D. ,  PIGNATO, Paul, A. ,  JAHNS, Scott, E. ,  USHER, Raymond, W.

IPC: A61B17/02

CPC classification number: A61B18/1485 ,  A61B18/1402 ,  A61B46/00 ,  A61B46/23 ,  A61B50/20 ,  A61B2018/00291 ,  A61B2090/306 ,  A61B2090/3614 ,  A61B2218/007 ,  A61M1/008

Abstract: A tubular suction tool (10) for accessing an anatomic surface or anatomic space and particularly the pericardium to access pericardial space and the epicardial surface of the heart to implant cardiac leads (90) in a minimally invasive manner are disclosed. The suction tool incorporates a suction pad (30) concave wall defining a suction cavity, a plurality of suction ports (42) arrayed about the concave wall, and a suction lumen, to form a bleb of tissue into the suction cavity when suction is applied. The suction cavity extends along one side of the suction pad, so that the suction pad and suction cavity can be applied tangentially against a tissue site. The suction tool can incorporate light emission (52) and video imaging of tissue adjacent the suction pad. A working lumen (20) terminating in a working lumen port (46) into the suction cavity enables introduction of tools, cardiac leads, and other instruments, cells, drugs or materials into or through the tissue bleb drawn into the suction cavity.

Abstract translation: 公开了一种用于访问解剖学表面或解剖空间的管状抽吸工具（10），特别是用于进入心包的心包和心外膜表面以微创方式植入心脏引线（90）。 抽吸工具包括限定吸入腔的吸盘（30）凹壁，围绕凹壁排列的多个吸入口（42）和抽吸腔，以在抽吸时形成吸入腔中的组织泡 。 吸入腔沿着吸盘的一侧延伸，使得吸力垫和抽吸腔可以相对于组织部位切向施加。 吸入工具可以包含发光（52）和邻近吸盘的组织的视频成像。 终止于进入吸入腔的工作管腔端口（46）的工作腔（20）能够将工具，心脏引线以及其它器械，细胞，药物或材料引入到吸入腔中的组织水泡中或穿过其中。

公开(公告)号：WO2004043267A3

公开(公告)日：2004-05-27

申请号：PCT/US2003/035449

申请日：2003-11-05

Applicant: MEDTRONIC, INC.

Inventor： HAARSTAD, Philip, J. ,  OLIG, Christopher ,  ROTHSTEIN, Paul, T. ,  STEINBERG, William, A. ,  KIM, David, J., S. ,  DAIGLE, Thomas, P. ,  THOMAS, Ann, M. ,  ROSS, Brian, J. ,  CHRISTIAN, Steven, C. ,  REETZ, Robert, H. ,  HOBDAY, Michael, J.

IPC: A61B17/02

Abstract: Suction-assisted tissue-engaging devices, systems, and methods are disclosed that can be employed through minimal surgical incisions to engage tissue during a medical procedure through application of suction to the tissue through a suction member applied to the tissue. A shaft is introduced into a body cavity through a first incision, and a suction head is attached to the shaft via a second incision. The suction head is applied against the tissue by manipulation of the shaft and suction is applied to engage the tissue while the medical procedure is performed through the second incision. A system coupled to the shaft and a fixed reference point stabilizes the shaft and suction head. When the medical procedure is completed, suction is discontinued, the suction head is detached from the shaft and withdrawn from the body cavity through the second incision, and the shaft is retracted through the first incision.

公开(公告)号：WO2003105933A1

公开(公告)日：2003-12-24

申请号：PCT/US2003/018591

申请日：2003-06-12

Applicant: MEDTRONIC, INC.

Inventor： MCINTOSH, Kevin, D. ,  ALBRECHT, Richard, M.

IPC: A61M5/19

CPC classification number: A61B17/00491 ,  A61B2017/00495 ,  A61C5/64 ,  A61M2005/3139

Abstract: A double syringe delivery system (5) is disclosed for holding a pair of syringes (10, 20) in a manner so as to accommodate the simultaneous activation of the plunger of each syringe in order to effect simultaneous delivery of the contents of each syringe. The delivery system includes a delivery mechanism for delivering the contents of both syringes to a site of application. The delivery system further includes a support member (30) that is positioned between the two syringe bodies. The elongated support member has resilient, C-shaped clamps (35, 36) on one end of the support member. The clamps are designed to be removably clamped onto the applicator so that the syringe barrels will be held together in a parallel manner. The elongated support member further comprises finger grips (32, 33). A plunger clip (40) connects the two syringe plungers so that they can also be simultaneously activated

Abstract translation: 公开了一种用于保持一对注射器（10,20）的双注射器输送系统（5），以便适应每个注射器的柱塞的同时激活，以便同时输送每个注射器的内容物。 递送系统包括用于将两个注射器的内容物递送到应用场所的递送机构。 输送系统还包括位于两个注射器体之间的支撑构件（30）。 细长的支撑构件在支撑构件的一端具有弹性的C形夹具（35,36）。 夹具被设计成可移除地夹紧在施用器上，使得注射器筒将以平行的方式保持在一起。 细长的支撑构件还包括手指夹（32,33）。 柱塞夹（40）连接两个注射器柱塞，使得它们也可以同时被激活

公开(公告)号：WO2003091814A1

公开(公告)日：2003-11-06

申请号：PCT/US2003/010106

申请日：2003-03-27

Applicant: MEDTRONIC, INC.

Inventor： JAHNS, Scott, E. ,  HOLMBERG, Glen

IPC: G05D16/10

CPC classification number: G05D16/2013 ,  A61B2017/00017 ,  A61B2017/00243 ,  A61B2017/0243 ,  A61B2017/306 ,  G05D16/10 ,  Y10S137/907 ,  Y10T137/7759 ,  Y10T137/7761

Abstract: A system, method and apparatus for regulating vacuum applied to surgical suction devices (20, 30) allowing the use of a single vacuum regulator (44) and associated canister to provide vacuum to two suction devices, such as a suction stabilizer (20) and a suction retractor (30). Vacuum controllers (50, 52) may be placed in the vacuum lines (54,56) provided to each of two or more suction devices, or may be placed only in the vacuum line of the suction device believed most likely to detach during the procedure.

Abstract translation: 一种用于调节施加到手术抽吸装置（20,30）上的真空的系统，方法和装置，允许使用单个真空调节器（44）和相关联的罐来向两个抽吸装置（例如吸力稳定器）提供真空，并且 抽吸牵开器（30）。 真空控制器（50,52）可以放置在设置到两个或更多个抽吸装置中的每一个的真空管线（54,56）中，或者可以仅放置在被认为最可能在程序中分离的抽吸装置的真空管线中 。