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公开(公告)号：WO2019032474A1
公开(公告)日：2019-02-14
申请号：PCT/US2018/045433
申请日：2018-08-06
Applicant: PULSE BIOSCIENCES, INC.
Inventor： DANITZ, David, J. , HINMAN, Cameron, D. , EBBERS, Edward , NUCCITELLI, Richard, L. , MOSS, Kevin, L. , UECKER, Darrin, R.
Abstract: Methods and apparatuses for treating a tissue with an electric treatment by rotating a pattern of electrodes partway through a treatment is disclosed. Also described herein are methods and apparatuses to treat tissue, including treating skin disorders, by selectively de-nucleating epidermal cells without provoking a significant inflammatory response, e.g., without increasing the density of leukocytes in the treated skin, and without affecting the non-cellular components of the dermis.
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2.发明申请
公开(公告)号：WO2020142415A3
公开(公告)日：2020-07-09
申请号：PCT/US2019/068912
申请日：2019-12-30
Applicant: NANOSCOPE TECHNOLOGIES LLC
Inventor： IDIGO, Chinenye, Abiodun , MOHANTY, Samarendra, Kumar
IPC: C07K14/195 , A61K38/16 , C12N15/85
Abstract: Some embodiments of the present invention generally relate to the novel method, compositions and applications of mechanosensitive channels in therapeutics for visual, neurological and other disorders. Specifically, some embodiments of the invention relate to exploitation of mechanosensitive channels' intrinsic property as a transgenic pressure modulator and alternative outflow actuator in the treatment of different diseases such as glaucoma, dry eye disease and other diseases involving of cells prone to mechanical or osmotic stress. Furthermore, some embodiments of the invention relate to exploitation of mechanosensitive channels for stimulation of cells as well as molecular delivery to cells triggered by internal as well as external mechanical stimuli.
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3.发明申请
公开(公告)号：WO2019213644A1
公开(公告)日：2019-11-07
申请号：PCT/US2019/030818
申请日：2019-05-06
Applicant: INTEMATIX CORPORATION
Inventor： WANG, Gang , LI, Yi-Qun
Abstract: There is provided a light emitting device comprising: an excitation source operable to generate excitation light with a dominant wavelength in a range 450 nm to 470 nm; a red photoluminescence material which generates light with a peak emission wavelength in a range 600 nm to 620 nm with a full width at half maximum emission intensity greater than 70 nm and less than 80 nm; a yellow to green photoluminescence material which generates light with a peak emission wavelength in a range 530 nm to 550 nm; and a narrow-band red photoluminescence material which generates light with a peak emission wavelength in a range 625 nm to 635 nm with a full width at half maximum emission intensity greater than about 5 nm and less than about 25nm.
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公开(公告)号：WO2019118959A1
公开(公告)日：2019-06-20
申请号：PCT/US2018/065952
申请日：2018-12-17
Applicant: INTEMATIX CORPORATION
Inventor： LI, Yi-Qun , SHEN, Xiongfei , WANG, Gang
Abstract: A white light emitting device or LED-filament comprises: a solid-state light emitter (LED) operable to generate excitation light; a first phosphor associated with the solid-state light emitter to generate light with a peak emission wavelength in a range 500 nm to 575 nm; and a second phosphor associated with the solid-state light emitter to generate light with a peak emission wavelength in a range 600 nm to 650 nm, wherein a percentage decrease in conversion efficiency corresponding to an increase in excitation light photon density exhibited by the second phosphor is larger than a percentage decrease in conversion efficiency corresponding to the same increase in excitation light photon density exhibited by the first phosphor.
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5.发明申请
公开(公告)号：WO2019005597A1
公开(公告)日：2019-01-03
申请号：PCT/US2018/038928
申请日：2018-06-22
Applicant: INTEMATIX CORPORATION
Inventor： LI, Yi-Qun
Abstract: Light emitting devices and LED-filaments comprise an excitation source (e.g. LED) and a photoluminescence material comprising a combination of a first narrow-band red photoluminescence material which generates light with a peak emission wavelength in a range 580 nm to 628 nm and a full width at half maximum emission intensity in a range 45 nm to 60 nm and a second narrow-band red photoluminescence material generates light with a peak emission wavelength in a range 628 nm to 640 nm and a full width at half maximum emission intensity in a range 5 nm to 20 nm. At least one of the first and second narrow-band red photoluminescence materials can comprise a narrow-band red phosphor or a quantum dot (QD) material.
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Patent Agency Ranking
公开(公告)号：WO2005023320A2
公开(公告)日：2005-03-17
申请号：PCT/US2004/028902
申请日：2004-09-03
Applicant: CARDICA, INC.
Inventor： BENDER, Theodore, M. , DUBOIS, Brian, R. , POMEROY, Dan, M. , CHAMNESS, sCOTT, O. , DONOHOE, Brendan, M.
IPC: A61L
CPC classification number: A61B17/32053 , A61B2010/0208 , A61B2017/1135 , A61B2017/320064 , A61B2017/349 , A61B2017/925 , A61B2017/928
Abstract: An piercing member is axially fixed to and positioned within a cutter, both of which are components of a stand-alone tool for creating an opening in the wall of a tubular tissue structure. The stand-alone tool includes an impulse source connected to the piercing member and to the cutter. An actuator is operationally connected to the impulse source, where the actuator causes the impulse source to release energy to and provide an impulse to the piercing member and the cutter. The tool may be configured to make multiple openings in the tissue of the same patient. Where the tool is configured to make multiple openings in the tissue of the same patient, the tool allows the piercing member and cutter to be moved back to an initial pre-deployment position after each use.
Abstract translation: 刺穿构件轴向地固定到切割器内并定位在切割器内，两者都是用于在管状组织结构的壁中产生开口的独立工具的部件。 独立工具包括连接到穿孔构件和切割器的脉冲源。 致动器可操作地连接到脉冲源，其中致动器使得脉冲源释放能量并向冲击构件和切割器提供冲击。 该工具可以被配置为在同一患者的组织中形成多个开口。 在工具被配置为在同一患者的组织中形成多个开口的情况下，该工具允许穿刺构件和切割器在每次使用之后移回到初始预部署位置。
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公开(公告)号：WO2021007123A1
公开(公告)日：2021-01-14
申请号：PCT/US2020/040809
申请日：2020-07-03
Applicant: INTEMATIX CORPORATION
Inventor： LI, Yi-Qun , YUAN, Xianglong , ZHAO, Jun-Gang
IPC: H01L25/075 , H01L33/50
Abstract: A full spectrum white light emitting device may include a broadband solid-state excitation source for generating broadband excitation light with a dominant wavelength from about 420 nm to about 480 nm and a FWHM intensity greater than about 25 nm; and a narrowband red photoluminescence material with an emission peak wavelength from about 620nm to about 640 nm and a FWHM intensity of less than about 30 nm. The device has an efficacy of at least 130 lm/W and generates white light with a CRI Ra > 90, and where over a wavelength range from about 430 nm to about 520 nm, a maximum percentage intensity deviation of the white light from the intensity of light of a black-body curve or CIE Standard Illuminant D is less than about 50%.
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公开(公告)号：WO2020190921A1
公开(公告)日：2020-09-24
申请号：PCT/US2020/023110
申请日：2020-03-17
Applicant: INTEMATIX CORPORATION
Inventor： WANG, Gang , ZHAO, Jun-Gang , LI, Yi-Qun
IPC: H01L25/075 , H01L33/50
Abstract: An LED-filament comprising: a partially light-transmissive substrate; an array of LED chips on a front face of the substrate; first broad-band green to red photoluminescence materials and a first narrow-band manganese-activated fluoride red photoluminescence material covering the array of LED chips and the front face of the substrate; and second broad-band green to red photoluminescence materials covering the back face of the substrate. The LED-filament can comprise: no narrow-band manganese-activated fluoride red photoluminescence material on the back face of the substrate, or a second narrow-band manganese-activated fluoride red photoluminescence material on the back face of the substrate in an amount up to 5 wt% of a total red photoluminescence material content on the back face of the substrate.
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公开(公告)号：WO2020190914A1
公开(公告)日：2020-09-24
申请号：PCT/US2020/023095
申请日：2020-03-17
Applicant: INTEMATIX CORPORATION
Inventor： ZHAO, Jun-Gang , WANG, Gang , LI, Yi-Qun
IPC: H01L33/50 , H01L25/075 , C09K11/61
Abstract: A white light emitting package (20) comprises: a solid-state excitation source (LED 30) for generating excitation light with a dominant wavelength in a range 440nm to 470nm; and a layered photoluminescence structure. The layered photoluminescence structure comprises a first photoluminescence layer (32) comprising from 75 wt% to 100 wt% of a manganese-activated fluoride photoluminescence material of the total photoluminescence material content of the first photoluminescence layer, and a second photoluminescence layer (34) comprising photoluminescence material for generating light with a peak emission wavelength in a range from 500 nm to 650 nm. The second photoluminescence layer is disposed on the first photoluminescence layer and the first photoluminescence layer is adjacent to the solid-state excitation source than the second photoluminescence layer.
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公开(公告)号：WO2020180841A1
公开(公告)日：2020-09-10
申请号：PCT/US2020/020741
申请日：2020-03-03
Applicant: BRIDGELUX, INC.
Inventor： CUMPSTON, Brian , RAI, Shiva , WILLIS-KILGROE, Linden , DODDA, Sudeep, Reddy
Abstract: There is provided a system comprising a driver and a control module, the control module capable of translating a received control signal having a first control scheme into a driver control signal having a predetermined second control scheme; and wherein the driver is configured for generating a driver output based on the identity of the first control scheme and the driver control signal. A driver, control module, and a method of controlling an LED system are also provided.
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