公开(公告)号：WO2005089164A3

公开(公告)日：2005-12-01

申请号：PCT/US2005000077

申请日：2005-01-03

Applicant: EPIMMUNE INC ,  INNOGENETICS NV ,  CHESNUT ROBERT ,  NEWMAN MARK J ,  MOTHE BIANCA ,  BAKER DENISE ,  SOUTHWOOD SCOTT ,  BABE LILIA MARIA ,  CHEN YIYOU ,  DEYOUNG LAWRENCE M ,  HUANG MANLEY T F ,  POWER SCOTT D

Inventor： CHESNUT ROBERT ,  NEWMAN MARK J ,  MOTHE BIANCA ,  BAKER DENISE ,  SOUTHWOOD SCOTT ,  BABE LILIA MARIA ,  CHEN YIYOU ,  DEYOUNG LAWRENCE M ,  HUANG MANLEY T F ,  POWER SCOTT D

IPC: A61K39/00 ,  A61K39/12 ,  C07K14/025

CPC classification number: A61K39/0011 ,  A61K39/00 ,  A61K39/12 ,  A61K2039/5158 ,  A61K2039/53 ,  A61K2039/545 ,  A61K2039/57 ,  A61K2039/645 ,  C07K14/005 ,  C12N7/00 ,  C12N2710/20022 ,  C12N2710/20034

Abstract: This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare human papillomavirus (HPV) epitopes, and to develop epitope-based vaccines directed towards HPV. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of HPV infection.

Abstract translation: 本发明使用我们关于T细胞识别和制备人乳头瘤病毒（HPV）表位以及开发针对HPV的基于表位的疫苗的机制的知识。 更具体地说，该应用传达了我们对药物组合物的发现和用于预防和治疗HPV感染的方法。

公开(公告)号：WO2012149333A9

公开(公告)日：2013-08-01

申请号：PCT/US2012035472

申请日：2012-04-27

Applicant: DANISCO US INC ,  JONES BRIAN E ,  KOLKMAN MARC ,  QIAN ZHEN ,  LAURSEN BRIAN SOGAARD ,  KRAGH KARSTEN M ,  PRICELIUS SINA ,  YU ZHEYONG ,  BABE LILIA MARIA ,  ESTABROOK MELODIE ,  HUA LING

Inventor： JONES BRIAN E ,  KOLKMAN MARC ,  QIAN ZHEN ,  LAURSEN BRIAN SOGAARD ,  KRAGH KARSTEN M ,  PRICELIUS SINA ,  YU ZHEYONG ,  BABE LILIA MARIA ,  ESTABROOK MELODIE ,  HUA LING

IPC: C12N9/42

CPC classification number: C11D3/38636 ,  C12C5/004 ,  C12N9/2405 ,  C12N9/2491 ,  C12N9/2494 ,  C12Y302/01078

Abstract: The present compositions and methods relate to an endo-B-mannanase cloned from a Bacillus sp., polynucleotides encoding the endo-B-mannanase, and methods of use thereof. Formulations containing the endo-beta-mannanase are highly suitable for use as detergents.

Abstract translation: 本发明的组合物和方法涉及从Bacillus sp。，编码内切-B-甘露聚糖酶的多核苷酸克隆的内切-B-甘露聚糖酶及其使用方法。 含有β-内酰基β-甘露聚糖酶的制剂非常适合用作洗涤剂。

公开(公告)号：WO2012149333A1

公开(公告)日：2012-11-01

申请号：PCT/US2012/035472

申请日：2012-04-27

Applicant: DANISCO US INC. ,  JONES, Brian E. ,  KOLKMAN, Marc ,  QIAN, Zhen ,  LAURSEN, Brian Sogaard ,  KRAGH, Karsten M. ,  PRICELIUS, Sina ,  YU, Zheyong ,  BABE, Lilia Maria ,  ESTABROOK, Melodie ,  HUA, Ling

Inventor： JONES, Brian E. ,  KOLKMAN, Marc ,  QIAN, Zhen ,  LAURSEN, Brian Sogaard ,  KRAGH, Karsten M. ,  PRICELIUS, Sina ,  YU, Zheyong ,  BABE, Lilia Maria ,  ESTABROOK, Melodie ,  HUA, Ling

IPC: C12N9/42

CPC classification number: C11D3/38636 ,  C12C5/004 ,  C12N9/2405 ,  C12N9/2491 ,  C12N9/2494 ,  C12Y302/01078

Abstract: The present compositions and methods relate to an endo-B-mannanase cloned from a Bacillus sp ., polynucleotides encoding the endo-B-mannanase, and methods of use thereof. Formulations containing the endo-β-mannanase are highly suitable for use as detergents.

Abstract translation: 本发明的组合物和方法涉及从Bacillus sp。，编码内切-B-甘露聚糖酶的多核苷酸克隆的内切-B-甘露聚糖酶及其使用方法。 含有β-内酰基β-甘露聚糖酶的制剂非常适合用作洗涤剂。

公开(公告)号：WO2005089164A2

公开(公告)日：2005-09-29

申请号：PCT/US2005/000077

申请日：2005-01-03

Applicant: EPIMMUNE INC. ,  INNOGENETICS N.V. ,  CHESNUT, Robert ,  NEWMAN, Mark, J. ,  MOTHE, Bianca ,  BAKER, Denise ,  SOUTHWOOD, Scott ,  BABE, Lilia, Maria ,  CHEN, Yiyou ,  DEYOUNG, Lawrence, M. ,  HUANG, Manley, T., F. ,  POWER, Scott, D.

Inventor： CHESNUT, Robert ,  NEWMAN, Mark, J. ,  MOTHE, Bianca ,  BAKER, Denise ,  SOUTHWOOD, Scott ,  BABE, Lilia, Maria ,  CHEN, Yiyou ,  DEYOUNG, Lawrence, M. ,  HUANG, Manley, T., F. ,  POWER, Scott, D.

IPC: A61K39/00 ,  A61K39/12 ,  C07K14/025

CPC classification number: A61K39/0011 ,  A61K39/00 ,  A61K39/12 ,  A61K2039/5158 ,  A61K2039/53 ,  A61K2039/545 ,  A61K2039/57 ,  A61K2039/645 ,  C07K14/005 ,  C12N7/00 ,  C12N2710/20022 ,  C12N2710/20034

Abstract: This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare human papillomavirus (HPV) epitopes, and to develop epitope-based vaccines directed towards HPV. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of HPV infection.

Abstract translation: 本发明使用我们对抗原被T细胞识别并制备人乳头状瘤病毒（HPV）表位的机制的知识，并开发针对HPV的基于表位的疫苗。 更具体地说，本申请介绍了我们在预防和治疗HPV感染中的药物组合物和使用方法的发现。

公开(公告)号：WO2017192692A1

公开(公告)日：2017-11-09

申请号：PCT/US2017/030800

申请日：2017-05-03

Applicant: DANISCO US INC ,  BABE, Lilia Maria ,  BASLER, Joshua Roy ,  ESTELL, David A. ,  ALEKSEYEV, Viktor Yuryevich

Inventor： BABE, Lilia Maria ,  BASLER, Joshua Roy ,  ESTELL, David A. ,  ALEKSEYEV, Viktor Yuryevich ,  WILDES, David Edward ,  MUNOS, Jeffrey Wayne ,  AMIN, Neelam S. ,  MARQUEZ, David ,  HUANG, Victoria ,  VEERAMUTHU, Geetha ,  OTSUKA, Rei ,  SOUTER, Philip F. ,  TARBIT, David John ,  JACKSON, Michelle ,  PEREZ-PRAT VINUESA, Eva Maria ,  MAGENNIS, Euan John

IPC: C12N9/54 ,  C11D3/386

Abstract: Disclosed herein is one or more subtilisin variant useful for cleaning applications and in methods of cleaning. One embodiment is directed to one or more subtilisin variant, including one or more Bacillus sp . subtilisin polypeptide variant, and one or more cleaning composition comprising one or more such variant.

Abstract translation: 本文公开了一种或多种可用于清洁应用和清洁方法的枯草杆菌蛋白酶变体。 一个实施方案涉及一种或多种枯草杆菌蛋白酶变体，包括一种或多种芽孢杆菌属（Bacillus sp。）。 枯草杆菌蛋白酶多肽变体和一种或多种包含一种或多种此类变体的清洁组合物

公开(公告)号：WO2012149325A1

公开(公告)日：2012-11-01

申请号：PCT/US2012/035463

申请日：2012-04-27

Applicant: DANISCO US INC. ,  JONES, Brian, E. ,  KOLKMAN, Marc ,  QIAN, Zhen ,  LAURSEN, Brian, Sogaard ,  KRAGH, Karsten, M. ,  PRICELIUS, Sina ,  YU, Zheyong ,  BABE, Lilia, Maria ,  ESTABROOK, Melodie ,  HUA, Ling

Inventor： JONES, Brian, E. ,  KOLKMAN, Marc ,  QIAN, Zhen ,  LAURSEN, Brian, Sogaard ,  KRAGH, Karsten, M. ,  PRICELIUS, Sina ,  YU, Zheyong ,  BABE, Lilia, Maria ,  ESTABROOK, Melodie ,  HUA, Ling

IPC: C07K14/195 ,  C12N9/24 ,  A23K1/165 ,  A23L1/00

CPC classification number: C11D3/38636 ,  A23K10/14 ,  A23K20/189 ,  C12C5/004 ,  C12N9/2402 ,  C12N9/2494 ,  C12Y302/01078

Abstract: The present compositions and methods relate to an endo-B-mannanase cloned from Geobacillus tepidamans , polynucleotides encoding the endo-B-mannanase, and methods of use thereof. Formulations containing the endo-β-mannanase are highly suitable for use as detergents.

Abstract translation: 本发明的组合物和方法涉及从土曲氏苔丝菌Tepidamans克隆的内切-B-甘露聚糖酶，编码内-B-甘露聚糖酶的多核苷酸及其使用方法。 含有β-内酰基β-甘露聚糖酶的制剂非常适合用作洗涤剂。

公开(公告)号：WO2012149317A1

公开(公告)日：2012-11-01

申请号：PCT/US2012/035454

申请日：2012-04-27

Applicant: DANISCO US INC. ,  JONES, Brian E. ,  KOLKMAN, Marc ,  QIAN, Zhen ,  LAURSEN, Brian Sogaard ,  KRAGH, Karsten M. ,  PRICELIUS, Sina ,  YU, Zheyong ,  BABE, Lilia Maria ,  ESTABROOK, Melodie

Inventor： JONES, Brian E. ,  KOLKMAN, Marc ,  QIAN, Zhen ,  LAURSEN, Brian Sogaard ,  KRAGH, Karsten M. ,  PRICELIUS, Sina ,  YU, Zheyong ,  BABE, Lilia Maria ,  ESTABROOK, Melodie

IPC: C07K14/435 ,  C12N9/24 ,  A23K1/00 ,  A23L1/00 ,  C07K14/195

CPC classification number: C12N9/2494 ,  A23K10/14 ,  A23K20/189 ,  A23K50/10 ,  A23K50/30 ,  A23K50/60 ,  A23K50/75 ,  A23K50/80 ,  C07K14/435 ,  C11D3/38636 ,  C12C5/004 ,  C12N9/2491 ,  C12Y302/01078 ,  Y02A40/818

Abstract: The present compositions and methods relate to an endo-β-mannanase cloned from Bacillus agaradhaerens , polynucleotides encoding the endo-β-mannanase, and methods of use thereof. Formulations containing the endo-β-mannanase are highly suitable for use as detergents.

Abstract translation: 本发明的组合物和方法涉及从琼脂琼脂糖芽孢杆菌克隆的内切β-甘露聚糖酶，编码内切β-甘露聚糖酶的多核苷酸及其使用方法。 含有β-内酰基β-甘露聚糖酶的制剂非常适合用作洗涤剂。