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    SERINE PROTEASES, NUCLEIC ACIDS ENCODING SERINE ENZYMES AND VECTORS AND HOST CELLS INCORPORATING SAME
    3.
    发明申请
    SERINE PROTEASES, NUCLEIC ACIDS ENCODING SERINE ENZYMES AND VECTORS AND HOST CELLS INCORPORATING SAME 审中-公开
    丝氨酸蛋白酶，核酸编码丝氨酸酶和载体和宿主细胞

    公开(公告)号：WO2005052146A8

    公开(公告)日：2006-08-24

    申请号：PCT/US2004039066

    申请日：2004-11-19

    申请人： GENENCOR INT ,  PROCTER & GAMBLE ,  JONES BRIAN EDWARD ,  KOLKMAN MARC ,  LEEFLANG CHRIS ,  OH HIROSHI ,  POULOSE AYROOKARAN J ,  SADLOWSKI EUGENE S ,  SHAW ANDREW ,  VAN DER KLEIJ WILHELMUS A H ,  VAN MARREWIJK LEO

    发明人： JONES BRIAN EDWARD ,  KOLKMAN MARC ,  LEEFLANG CHRIS ,  OH HIROSHI ,  POULOSE AYROOKARAN J ,  SADLOWSKI EUGENE S ,  SHAW ANDREW ,  VAN DER KLEIJ WILHELMUS A H ,  VAN MARREWIJK LEO

    IPC分类号： C11D3/386 ,  C12N9/52 ,  C12N9/64

    CPC分类号： C12N9/52 ,  C07K2299/00 ,  C11D3/386

    摘要： The present invention provides novel serine proteases, novel genetic material encoding these enzymes, and proteolytic proteins obtained from Micrococcineae spp., including but not limited to Cellulomonas spp. and variant proteins developed therefrom. In particular, the present invention provides protease compositions obtained from a Cellulomonas spp, DNA encoding the protease, vectors comprising the DNA encoding the protease, host cells transformed with the vector DNA, and an enzyme produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising protease(s) obtained from a Micrococcineae spp., including but not limited to Cellulomonas spp. In alternative embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These mutant proteases also find use in numerous applications.

    摘要翻译： 本发明提供了新的丝氨酸蛋白酶，编码这些酶的新型遗传物质，以及从微球菌属（Micrococcineae spp。）获得的蛋白水解蛋白，包括但不限于纤维单胞菌属（Cellulomonas spp） 和从其开发的变体蛋白质。 特别地，本发明提供了从纤维单胞菌属（Splulomonas spp）获得的蛋白酶组合物，编码蛋白酶的DNA，包含编码蛋白酶的载体，载体DNA转化的宿主细胞和由宿主细胞产生的酶。 本发明还提供了清洁组合物（例如洗涤剂组合物），动物饲料组合物，以及包含从微球菌（Micrococcineae spp。）获得的蛋白酶的纺织和皮革加工组合物，其包括但不限于纤维单胞菌属（Cellulomonas spp） 在替代实施方案中，本发明提供衍生自本文所述的野生型蛋白酶的突变体（即，变体）蛋白酶。 这些突变型蛋白酶也可用于许多应用。

    SERINE PROTEASES, NUCLEIC ACIDS ENCODING SERINE ENZYMES AND VECTORS AND HOST CELLS INCORPORATING SAME
    4.
    发明申请
    SERINE PROTEASES, NUCLEIC ACIDS ENCODING SERINE ENZYMES AND VECTORS AND HOST CELLS INCORPORATING SAME 审中-公开
    丝氨酸蛋白酶，编码丝氨酸酶的核酸以及包含相同物质的载体和宿主细胞

    公开(公告)号：WO2005052161A2

    公开(公告)日：2005-06-09

    申请号：PCT/US2004/039006

    申请日：2004-11-19

    申请人： GENENCOR INTERNATIONAL, INC. ,  JONES, Brian, Edward ,  KOLKMAN, Marc ,  LEEFLANG, Chris ,  POULOSE, Ayrookaran, J. ,  SHAW, Andrew ,  VAN DER KLEIJ, Wilhelmus, A., H. ,  VAN MARREWIJK, Leo

    发明人： JONES, Brian, Edward ,  KOLKMAN, Marc ,  LEEFLANG, Chris ,  POULOSE, Ayrookaran, J. ,  SHAW, Andrew ,  VAN DER KLEIJ, Wilhelmus, A., H. ,  VAN MARREWIJK, Leo

    IPC分类号： C12N15/53

    CPC分类号： C12N9/52 ,  C07K2299/00 ,  C11D3/386

    摘要： The present invention provides novel serine proteases, novel genetic material encoding these enzymes, and proteolytic proteins obtained from Micrococcineae spp., including but not limited to Cellulomonas spp. and variant proteins developed therefrom. In particular, the present invention provides protease compositions obtained from a Cellulomonas spp, DNA encoding the protease, vectors comprising the DNA encoding the protease, host cells transformed with the vector DNA, and an enzyme produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising protease(s) obtained from a Micrococcineae spp., including but not limited to Cellulomonas spp. In alternative embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These mutant proteases also find use in numerous applications.

    摘要翻译： 本发明提供了新的丝氨酸蛋白酶，编码这些酶的新型遗传物质和从微球菌属物种获得的蛋白水解蛋白质，包括但不限于纤维单胞菌属， 我>属。 和由其开发的变体蛋白。 具体地说，本发明提供了由纤维单胞菌属（Cellulomonas spp。）获得的蛋白酶组合物，编码蛋白酶的DNA，包含编码蛋白酶的DNA的载体，用载体DNA转化的宿主细胞和由宿主产生的酶 细胞。 本发明还提供了从微球菌属物种获得的包含蛋白酶的清洁组合物（例如洗涤剂组合物），动物饲料组合物和纺织品和皮革加工组合物，包括但不限于纤维单胞的属。 在替代实施方案中，本发明提供了衍生自本文所述野生型蛋白酶的突变（即，变体）蛋白酶。 这些突变蛋白酶也可用于多种应用。

    SERINE PROTEASES, NUCLEIC ACIDS ENCODING SERINE ENZYMES AND VECTORS AND HOST CELLS INCORPORATING SAME
    5.
    发明申请
    SERINE PROTEASES, NUCLEIC ACIDS ENCODING SERINE ENZYMES AND VECTORS AND HOST CELLS INCORPORATING SAME 审中-公开
    丝氨酸蛋白酶，编码丝氨酸酶的核酸以及包含相同物质的载体和宿主细胞

    公开(公告)号：WO2005052146A2

    公开(公告)日：2005-06-09

    申请号：PCT/US2004039066

    申请日：2004-11-19

    申请人： GENENCOR INT ,  PROCTER & GAMBLE ,  JONES BRIAN EDWARD ,  KOLKMAN MARC ,  LEEFLANG CHRIS ,  OH HIROSHI ,  POULOSE AYROOKARAN J ,  SADLOWSKI EUGENE S ,  SHAW ANDREW ,  VAN DER KLEIJ WILHELMUS A H ,  VAN MARREWIJK LEO

    发明人： JONES BRIAN EDWARD ,  KOLKMAN MARC ,  LEEFLANG CHRIS ,  OH HIROSHI ,  POULOSE AYROOKARAN J ,  SADLOWSKI EUGENE S ,  SHAW ANDREW ,  VAN DER KLEIJ WILHELMUS A H ,  VAN MARREWIJK LEO

    IPC分类号： C11D3/386 ,  C12N9/52 ,  C12N9/64 ,  C12N9/00

    CPC分类号： C12N9/52 ,  C07K2299/00 ,  C11D3/386

    摘要： The present invention provides novel serine proteases, novel genetic material encoding these enzymes, and proteolytic proteins obtained from Micrococcineae spp., including but not limited to Cellulomonas spp. and variant proteins developed therefrom. In particular, the present invention provides protease compositions obtained from a Cellulomonas spp, DNA encoding the protease, vectors comprising the DNA encoding the protease, host cells transformed with the vector DNA, and an enzyme produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising protease(s) obtained from a Micrococcineae spp., including but not limited to Cellulomonas spp. In alternative embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These mutant proteases also find use in numerous applications.

    摘要翻译： 本发明提供了新的丝氨酸蛋白酶，编码这些酶的新颖遗传物质和从微球菌属物种获得的蛋白水解蛋白，包括但不限于纤维单胞菌属物种。 和由其开发的变体蛋白。 具体而言，本发明提供了由纤维单胞菌属（Cellulomonas spp）获得的蛋白酶组合物，编码蛋白酶的DNA，包含编码蛋白酶的DNA的载体，用载体DNA转化的宿主细胞和由宿主细胞产生的酶。 本发明还提供了包含从微球菌属物种获得的蛋白酶的清洁组合物（例如洗涤剂组合物），动物饲料组合物和纺织品和皮革加工组合物，所述蛋白酶包括但不限于纤维单胞菌属物种。 在替代实施方案中，本发明提供了衍生自本文所述野生型蛋白酶的突变（即，变体）蛋白酶。 这些突变蛋白酶也可用于多种应用。