公开(公告)号：WO2011099006A2

公开(公告)日：2011-08-18

申请号：PCT/IL2011/000145

申请日：2011-02-10

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD. ,  MILO, Ron ,  BAR-EVEN, Arren ,  NOOR, Elad

Inventor： MILO, Ron ,  BAR-EVEN, Arren ,  NOOR, Elad

IPC: C12N15/82 ,  C12N9/00 ,  C12N9/88 ,  C12N9/02 ,  C12N9/04 ,  C12N9/10 ,  C12N9/18 ,  C12N9/90 ,  G06F19/12

CPC classification number: C12N9/93 ,  C12N9/0006 ,  C12N9/0008 ,  C12N9/1018 ,  C12N9/1205 ,  C12N9/13 ,  C12N9/18 ,  C12N9/88 ,  C12N9/90 ,  C12N15/70 ,  C12N15/8245 ,  C12N15/8247 ,  C12N15/8269 ,  C12P7/40 ,  C12P7/42 ,  C12P7/46 ,  C12P11/00 ,  C12Y101/01059 ,  C12Y102/01018 ,  C12Y201/03001 ,  C12Y208/03001 ,  C12Y401/01031 ,  C12Y402/01017 ,  C12Y402/01054 ,  C12Y604/01001 ,  C12Y604/01002 ,  G06F19/12 ,  Y02P20/52

Abstract: A system for carbon fixation is provided. The system comprises enzymes which catalyze reactions of a carbon fixation pathway, wherein at least one of the reactions of the carbon fixation pathway is a carboxylation reaction, wherein products of the reactions of the carbon fixation pathway comprise oxaloacetate and malonyl-CoA, wherein an enzyme which performs the carboxylation reaction is selected from the group consisting of phophoenolpyruvate (PEP) carboxlase, pyruvate carboxylase and acetyl-CoA carboxylase and wherein an export product of the carbon fixation pathway is glyoxylate. Additional carbon fixation pathways are also provided and methods of generating same.

Abstract translation: 提供了一种用于碳固定的系统。 该系统包含催化碳固定途径的反应的酶，其中碳固定途径的至少一个反应是羧化反应，其中碳固定途径的反应产物包含草酰乙酸和丙二酰-CoA，其中酶 其中进行羧化反应的酶选自磷酸烯醇式丙酮酸（PEP）羧化酶，丙酮酸羧化酶和乙酰​​-CoA羧化酶，并且其中碳固定途径的出口产物是乙醛酸盐。 还提供了额外的碳固定途径和产生同样的方法。

公开(公告)号：WO2011099006A3

公开(公告)日：2011-11-10

申请号：PCT/IL2011000145

申请日：2011-02-10

Applicant: YEDA RES & DEV ,  MILO RON ,  BAR-EVEN ARREN ,  NOOR ELAD

Inventor： MILO RON ,  BAR-EVEN ARREN ,  NOOR ELAD

IPC: C12N15/82 ,  C12N9/00 ,  C12N9/02 ,  C12N9/04 ,  C12N9/10 ,  C12N9/18 ,  C12N9/88 ,  C12N9/90 ,  G06F19/12

CPC classification number: C12N9/93 ,  C12N9/0006 ,  C12N9/0008 ,  C12N9/1018 ,  C12N9/1205 ,  C12N9/13 ,  C12N9/18 ,  C12N9/88 ,  C12N9/90 ,  C12N15/70 ,  C12N15/8245 ,  C12N15/8247 ,  C12N15/8269 ,  C12P7/40 ,  C12P7/42 ,  C12P7/46 ,  C12P11/00 ,  C12Y101/01059 ,  C12Y102/01018 ,  C12Y201/03001 ,  C12Y208/03001 ,  C12Y401/01031 ,  C12Y402/01017 ,  C12Y402/01054 ,  C12Y604/01001 ,  C12Y604/01002 ,  G06F19/12 ,  Y02P20/52

Abstract: A system for carbon fixation is provided. The system comprises enzymes which catalyze reactions of a carbon fixation pathway, wherein at least one of the reactions of the carbon fixation pathway is a carboxylation reaction, wherein products of the reactions of the carbon fixation pathway comprise oxaloacetate and malonyl-CoA, wherein an enzyme which performs the carboxylation reaction is selected from the group consisting of phophoenolpyruvate (PEP) carboxlase, pyruvate carboxylase and acetyl-CoA carboxylase and wherein an export product of the carbon fixation pathway is glyoxylate. Additional carbon fixation pathways are also provided and methods of generating same.

Abstract translation: 提供了一种用于碳固定的系统。 该系统包括催化碳固定通道的反应的酶，其中碳固定通路的至少一个反应是羧化反应，其中碳固定路径的反应产物包括草酰乙酸和丙二酰辅酶A，其中酶 进行羧化反应的选自苯丙醇丙酮酸（PEP）羧基酶，丙酮酸羧化酶和乙酰​​辅酶A羧化酶，其中碳固定路径的出口产物是乙醛酸盐。 还提供了另外的碳固定路径和产生它们的方法。