公开(公告)号：WO2011110546A2

公开(公告)日：2011-09-15

申请号：PCT/EP2011053446

申请日：2011-03-08

Applicant: MAX PLANCK GESELLSCHAFT ,  BAUER BIANCA ,  MEYER THOMAS F

Inventor： BAUER BIANCA ,  MEYER THOMAS F

IPC: A61K31/00 ,  A61K31/15 ,  A61K31/155 ,  A61K31/18 ,  A61K31/285 ,  A61K31/351 ,  A61K31/404 ,  A61K31/41 ,  A61K31/4162 ,  A61K31/427 ,  A61K31/429 ,  A61K31/4439 ,  A61K31/47 ,  A61K31/4985 ,  A61K31/517 ,  A61K31/53 ,  A61K31/555 ,  A61K31/663 ,  A61K33/24 ,  A61K38/00 ,  A61K39/00 ,  A61P1/00 ,  A61P1/04 ,  A61P31/04 ,  G01N33/50

CPC classification number: A61K31/00 ,  A61K31/15 ,  A61K31/155 ,  A61K31/18 ,  A61K31/285 ,  A61K31/351 ,  A61K31/404 ,  A61K31/41 ,  A61K31/4162 ,  A61K31/427 ,  A61K31/429 ,  A61K31/4439 ,  A61K31/47 ,  A61K31/4985 ,  A61K31/517 ,  A61K31/53 ,  A61K31/555 ,  A61K31/663 ,  A61K33/24 ,  C12N2799/027 ,  C12N2799/06 ,  C12Q1/18 ,  G01N33/5041 ,  G01N2333/205 ,  G01N2333/71

Abstract: The present invention relates to a pharmaceutical composition comprising at least one inhibitor of SHP-2, optionally together with pharmaceutically acceptable carriers, adjuvants, diluents and/or additives. The present invention also relates to screening methods for identification of a compound suitable as inhibitor of SHP-2.

Abstract translation: 本发明涉及包含至少一种SHP-2抑制剂，任选与药学上可接受的载体，佐剂，稀释剂和/或添加剂的药物组合物。 本发明还涉及用于鉴定适合作为SHP-2抑制剂的化合物的筛选方法。

公开(公告)号：WO2011110546A3

公开(公告)日：2011-09-15

申请号：PCT/EP2011/053446

申请日：2011-03-08

Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V. ,  BAUER, Bianca ,  MEYER, Thomas F.

Inventor： BAUER, Bianca ,  MEYER, Thomas F.

IPC: A61K31/00 ,  A61K31/15 ,  A61K31/155 ,  A61K31/18 ,  A61K31/285 ,  A61K31/351 ,  A61K31/404 ,  A61K31/41 ,  A61K31/4162 ,  A61K31/427 ,  A61K31/429 ,  A61K31/4439 ,  A61K31/47 ,  A61K31/4985 ,  A61K31/517

Abstract: The present invention relates to a pharmaceutical composition comprising at least one inhibitor of SHP-2, optionally together with pharmaceutically acceptable carriers, adjuvants, diluents and/or additives. The present invention also relates to screening methods for identification of a compound suitable as inhibitor of SHP-2.