公开(公告)号：WO2021250058A2

公开(公告)日：2021-12-16

申请号：PCT/EP2021/065391

申请日：2021-06-09

Applicant: BAYER AKTIENGESELLSCHAFT ,  BAYER CROPSCIENCE LP

Inventor： KNYPHAUSEN, Philipp ,  VOGLER, Brian ,  COCO, Wayne ,  COHNEN, Andre ,  RICHTER, Florian ,  CURTIS, Damian

IPC: C12N15/63 ,  C12N9/22 ,  C12N15/62 ,  C07K14/21 ,  C07K14/435 ,  C07K2319/00 ,  C12N15/01 ,  C12N15/102 ,  C12N15/8213 ,  C12N2310/20

Abstract: Disclosed are new nucleic acid base-editing systems comprising fusion proteins comprising a) an RNA-programmable nucleic acid recognition module or other suitable nucleic acid recognition module, b) a light inducible reactive oxygen generator. Further disclosed are methods and kits to modify or mutagenize a target DNA region in prokaryotic or eukaryotic cells or organisms.

公开(公告)号：WO2021102380A1

公开(公告)日：2021-05-27

申请号：PCT/US2020/061682

申请日：2020-11-20

Applicant: BAYER CROPSCIENCE LP

Inventor： ESTIME, Bendy ,  ROCHA-VALADEZ, J. Antonio

IPC: C12N1/20 ,  C12N3/00 ,  C12P21/02 ,  C12N15/75 ,  C07K14/32 ,  A01N63/22 ,  A01N63/23 ,  C12N9/54 ,  C12N9/18 ,  C12N9/78

Abstract: The present invention provides a method for producing a fermentation product by culturing recombinant exosporium-producing Bacillus cells that express a fusion protein of interest on the exosporium in a medium containing sources of carbon and nitrogen in a total concentration of at least 20 g/L, resulting in a fermentation broth containing a high titer of the recombinant Bacillus spores.

公开(公告)号：WO2020181053A1

公开(公告)日：2020-09-10

申请号：PCT/US2020/021125

申请日：2020-03-05

Applicant: BAYER CROPSCIENCE LP

Inventor： BEAU, Jeremy ,  GOERTZ, Andreas ,  NEWMAN, Adam ,  SCHWIENTEK, Patrick ,  TAYLOR, Colleen S. ,  TIAN, Donglan ,  TRAAG, Bjorn A.

IPC: A01N63/25

Abstract: The present invention provides a composition comprising a biologically pure culture of a Paenibacillus sp. strain or a cell-free preparation thereof comprising a fusaricidin and a tridecaptin; wherein the fusaricidin is produced with a fusaricidin synthetase gene of fusA encoded by a DNA sequence exhibiting at least 90.5% sequence identity to SEQ ID NO: 3; and the tridecaptin is produced with a nonribosomal peptide synthetase (NRPS) gene of triE encoded by a DNA sequence exhibiting at least 90.0% sequence identity to SEQ ID NO: 7. Also provided are methods of treating an agricultural plant to control a disease and methods of increasing the vigor and/or crop yield of an agricultural plant with the disclosed compositions.

公开(公告)号：WO2020165043A1

公开(公告)日：2020-08-20

申请号：PCT/EP2020/053138

申请日：2020-02-07

Applicant: BAYER CROPSCIENCE LP ,  BAYER AKTIENGESELLSCHAFT

Inventor： ALLY, Dilara ,  ARMSTRONG, Don ,  GRAVES, Christopher ,  HEBING, Lukas ,  NIEDENFÜHR, Sebastian ,  TAYLOR, Colleen ,  NEWMAN, Adam

IPC: G06N3/12 ,  G06N20/20 ,  G06N3/00 ,  G06N3/04 ,  G06N5/00 ,  G06N7/00 ,  G06N20/10 ,  G06N3/08

Abstract: The present disclosure generally relates to systems and methods for optimizing a fermentation process. An exemplary method for optimizing a fermentation process comprises: subsampling a training dataset to obtain a plurality of subsampled datasets, wherein the training dataset includes data related to one or more previous instances of the fermentation process; training a plurality of mathematical models based on the plurality of subsampled datasets; identifying a plurality of sets of fermentation conditions based on the plurality of trained mathematical models; identifying one or more clusters of sets of fermentation conditions based on the plurality of sets of fermentation conditions; obtaining one or more fermentation design prototypes based on the one or more clusters; and determining a candidate fermentation condition for the fermentation process based on the one or more fermentation design prototypes.

公开(公告)号：WO2020097136A1

公开(公告)日：2020-05-14

申请号：PCT/US2019/059950

申请日：2019-11-06

Applicant: BAYER CROPSCIENCE LP

Inventor： WELLS, David ,  CLODFELTER, Mark ,  FARNO, Peter ,  NEWBERRY, Caitlin ,  BRUSNIKIN, Denis ,  CUDA, Max ,  HO, Sunia

IPC: G06Q30/02

Abstract: The present disclosure relates generally to methods for creating a product package for a user using that take into account both static and dynamic loyalty criteria. The present invention is particularly adapted to utilization by sectors such as the agricultural industry where real time updates along a supply chain would be beneficial to suppliers and distributors.

公开(公告)号：WO2019125403A1

公开(公告)日：2019-06-27

申请号：PCT/US2017/067224

申请日：2017-12-19

Applicant: BAYER CROPSCIENCE LP ,  RELIANCE PRODUCTS LTD.

Inventor： MATTSON, Doug ,  SMITH, Mark ,  SCOTT, Neil ,  BERGMAN, Ryan ,  RENKEL, Ron ,  BARTLETT, Glenn ,  BEERNAERT, David

IPC: B01F7/16 ,  B01F15/02 ,  B65D1/20

CPC classification number: B01F7/1695 ,  B01F7/00033 ,  B01F7/00066 ,  B01F7/00725 ,  B01F7/16 ,  B01F15/02 ,  B01F15/0291 ,  B65D1/20

Abstract: A mixing assembly (10) includes a drum (11) including a side wall (13), a top portion (15), and a bottom portion (17), in which the top portion (15) includes a first opening (19) for filling a substance into the drum (11), a second opening (12) for mixing the substance in the drum (11), and a third opening (14) for extracting the substance from the drum (11); and a mixer (105) releasably disposed in the drum (11), including a head (109) releasably attached to the second opening (12) for mixing, in which the head (109) includes a housing including an internal hollow region extending along the central axis of the head (109), and external threads configured to be attached to the second opening (12) for mixing by thread engagement, a shaft (107) disposed in the hollow region, and an impeller assembly (114) disposed at a bottom end of the shaft (107) for stirring the substance in the drum. The mixing assembly (10) also includes a a sump (16) that is substantially vertically aligned with the third opening (14) for extracting, wherein the bottom portion (17) is sloped toward the sump (16) so that the substance will flow along the sloped bottom portion (17) into the sump (16), wherein the sump (16) comprises a base defining a lowest surface of the bottom portion (17) so that the sump (16) will receive the substance that flows from the sloped bottom portion (17).

公开(公告)号：WO2018195256A1

公开(公告)日：2018-10-25

申请号：PCT/US2018/028271

申请日：2018-04-19

Applicant: BAYER CROPSCIENCE LP

Inventor： MANAVALAN, Lakshmi Praba ,  CARRIEDO, Leonela G.

IPC: A01N43/12 ,  A01N43/40 ,  A01N43/653 ,  A01N59/06 ,  A01N59/20 ,  A01N59/26 ,  A01N31/06 ,  A01N31/16 ,  A01P3/00 ,  A01P13/00 ,  A01P7/04 ,  A01P21/00

Abstract: The present invention relates to the use of antioxidants and/or nutrients for improving crop safety in plants, a composition comprising antioxidants and a new method of plant treatment wherein is antioxidants and/or nutrients applied to a plant, a plant part, plant propagation material or the habitat the plant is growing in to improve crop safety.

公开(公告)号：WO2018187301A1

公开(公告)日：2018-10-11

申请号：PCT/US2018/025849

申请日：2018-04-03

Applicant: BAYER CROPSCIENCE LP

Inventor： SEBASTIAN, Derek, J. ,  SPAK, David, R. ,  QUICKE, Harold, E.

IPC: A01N43/40 ,  A01N43/50 ,  A01N43/54 ,  A01N43/66 ,  A01P13/00 ,  A01P13/02

CPC classification number: A01N43/68 ,  A01N43/40 ,  A01N43/50 ,  A01N43/54 ,  A01N43/66 ,  Y02A90/40

Abstract: A method for wildfire control in a habitat that contains or could contain plants susceptible to wildfire includes applying to the habitat a composition containing a cellulose biosynthesis inhibitor. A method of controlling invasive plants in a habitat includes applying to the habitat a composition containing a cellulose biosynthesis inhibitor. A method for residual control of invasive plants in a habitat includes applying to the habitat a composition containing a cellulose biosynthesis inhibitor.

公开(公告)号：WO2018162329A1

公开(公告)日：2018-09-13

申请号：PCT/EP2018/055101

申请日：2018-03-01

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT ,  BAYER CROPSCIENCE LP

Inventor： LINKA, Marc ,  POREE, Fabien ,  LABER, Bernd ,  LANGE, Gudrun ,  THIES, Christina ,  WEBER, Ernst ,  STRERATH, Michael ,  GESKE, Sandra ,  BALVEN-ROSS, Heike ,  WOBST, Nina ,  COCO, Wayne ,  PAWLOWSKI, Nikolaus ,  TEBBE, Jan ,  DUBALD, Manuel

IPC: C12N9/02 ,  C12N15/82

CPC classification number: C12N9/0069 ,  C12N15/8274

Abstract: In the present invention, HPPD polypeptides and plants containing them showing a full tolerance against one or more HPPD inhibitor herbicides belonging to various chemical classes are described. A set of mutant HPPD polypeptides have been designed which have either no or only a significantly reduced affinity to HPPD inhibitor herbicides and, at the same time, the rate of dissociation of the HPPD inhibitors of the mutant HPPD polypeptide is increased to such an extent that the HPPD inhibitors no longer act as slow-binding or slow, tight-binding inhibitors but, instead of this, have become fully reversible inhibitors. In particular, isolated polynucleotides encoding mutant HPPD polypeptides conferring tolerance to HPPD inhibitor herbicides belonging to various chemical classes are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed.

公开(公告)号：WO2018081759A1

公开(公告)日：2018-05-03

申请号：PCT/US2017/059146

申请日：2017-10-31

Applicant: BAYER CROPSCIENCE LP

Inventor： KOOB, Jim

IPC: G06Q10/04 ,  G06Q50/02

Abstract: Systems and methods for generating crop yield maps are provided, in one example embodiment, a method can include accessing, by one or more processors, data indicative of crop yield for a field area; and accessing, by the one or more processors, one or more data types associated with the field area. Each of the data types can provide a geospatial distribution of data associated with vegetation across the field area. The method can further include determining, by the one or more processors, a crop yield distribution for the field area based at least in part on the data indicative of crop yield and the one or more data types; and generating, by the one or more processors, a yield map for the field area based at least in part on the crop yield distribution.

Abstract translation: 提供了用于生成作物产量图的系统和方法。在一个示例实施例中，一种方法可以包括由一个或多个处理器访问指示田地面积的农作物产量的数据; 以及由所述一个或多个处理器访问与所述字段区域相关联的一个或多个数据类型。 每种数据类型都可以提供与野外区域植被相关的数据的地理空间分布。 该方法可以进一步包括通过一个或多个处理器至少部分地基于指示作物产量和一种或多种数据类型的数据来确定田地面积的作物产量分布; 以及由所述一个或多个处理器至少部分地基于作物产量分布来生成田地面积的产量图。