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公开(公告)号:WO2013148736A1
公开(公告)日:2013-10-03
申请号:PCT/US2013/033948
申请日:2013-03-26
IPC分类号: C12N15/113 , A61K31/7088 , A61P17/02
CPC分类号: C12N15/1138 , A61K31/7105 , A61K31/713 , C12N2310/11 , C12N2310/14 , C12N2310/531 , A61K2300/00
摘要: Anti-cadherin and anti-ZO-1 agents and compositions, and kits containing them for use in the promotion and/or improvement of wound healing and/or tissue repair, and for anti- scarring, anti-inflammatory, anti-fibrosis and anti-adhesion indications.
摘要翻译: 抗钙粘蛋白和抗ZO-1剂和组合物,以及含有它们的用于促进和/或改善伤口愈合和/或组织修复以及用于抗瘢痕形成,抗炎,抗纤维化和抗 粘附适应症。
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公开(公告)号:WO2009085272A9
公开(公告)日:2010-06-10
申请号:PCT/US2008014023
申请日:2008-12-22
发明人: DUFT BRADFORD J , GREEN COLIN R , BECKER DAVID L
CPC分类号: A61K38/08 , A61K9/0051 , A61K38/10 , A61K38/385 , A61L17/005 , A61L27/54 , A61L31/08 , A61L31/10 , A61L31/16 , A61L2300/25 , A61L2300/252 , A61L2300/258 , A61L2300/432 , A61L2300/602 , A61L2300/606 , A61L2300/608
摘要: Medical devices comprising an anti-connexin agent suitable for introduction into a subject.
摘要翻译: 包括适合引入受试者的抗连接蛋白剂的医疗装置。
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3.USE OF ANTI-CONNEXIN 43 POLYNUCLEOTIDES FOR THE TREATMENT OF ABNORMAL OR EXCESSIVE SCARS 审中-公开
标题翻译: 使用抗连接蛋白43多核苷酸治疗异常或过敏性SCARS公开(公告)号:WO2009085277A3
公开(公告)日:2009-11-26
申请号:PCT/US2008014028
申请日:2008-12-22
发明人: BECKER DAVID L , GREEN COLIN R , DUFT BRADFORD J
IPC分类号: A61K31/7088 , A61P17/02 , A61P27/02 , A61P43/00 , C12N15/113 , C12Q1/00
CPC分类号: A61K31/7088 , C12N15/1138 , C12N2310/11 , G01N33/5008
摘要: Methods, compounds, compositions, kits and articles of manufacture comprising anti- connexin polynucleotides for prevention and/or treatment of abnormal scars, including keloid scars, hypertrophic scars, atrophic scars, and widespread scars.
摘要翻译: 包括用于预防和/或治疗异常瘢痕的抗连接蛋白多核苷酸的方法,化合物,组合物,试剂盒和制品,包括瘢痕疙瘩,肥大性瘢痕,萎缩性瘢痕和广泛的瘢痕。
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公开(公告)号:WO2009085277A2
公开(公告)日:2009-07-09
申请号:PCT/US2008/014028
申请日:2008-12-22
IPC分类号: A61K48/00
CPC分类号: A61K31/7088 , C12N15/1138 , C12N2310/11 , G01N33/5008
摘要: Methods, compounds, compositions, kits and articles of manufacture comprising anti- connexin polynucleotides for prevention and/or treatment of abnormal scars, including keloid scars, hypertrophic scars, atrophic scars, and widespread scars.
摘要翻译: 包括用于预防和/或治疗异常瘢痕的抗连接蛋白多核苷酸的方法,化合物,组合物,试剂盒和制品,包括瘢痕疙瘩,肥大性瘢痕,萎缩性瘢痕和广泛的瘢痕。
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公开(公告)号:WO2009085273A3
公开(公告)日:2009-07-09
申请号:PCT/US2008/014024
申请日:2008-12-22
摘要: Connexin modulation for the treatment of surgical adhesions, and associated methods, compositions, and articles.
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公开(公告)号:WO2009085272A2
公开(公告)日:2009-07-09
申请号:PCT/US2008/014023
申请日:2008-12-22
CPC分类号: A61K38/08 , A61K9/0051 , A61K38/10 , A61K38/385 , A61L17/005 , A61L27/54 , A61L31/08 , A61L31/10 , A61L31/16 , A61L2300/25 , A61L2300/252 , A61L2300/258 , A61L2300/432 , A61L2300/602 , A61L2300/606 , A61L2300/608
摘要: Medical devices comprising an anti-connexin agent suitable for introduction into a subject.
摘要翻译: 包括适合引入受试者的抗连接蛋白剂的医疗装置。
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7.
公开(公告)号:WO2009085269A3
公开(公告)日:2009-07-09
申请号:PCT/US2008/014020
申请日:2008-12-22
IPC分类号: C12N15/11 , A61K38/17 , A61K39/395 , A61P41/00
摘要: Methods, compounds, compositions, kits and articles of manufacture comprising anti- connexin agents for treatment of orthopedic disorder, disease, or condition, and promoting post-surgical wound-healing.
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公开(公告)号:WO2008060622A9
公开(公告)日:2008-11-27
申请号:PCT/US2007024085
申请日:2007-11-15
发明人: GREEN COLIN R , DUFT BRADFORD J , BECKER DAVID L
IPC分类号: A61K38/18 , A61K31/711
CPC分类号: A61K31/711 , A61K35/33 , A61K35/36 , A61K38/1754 , A61K38/1825 , A61K38/1841 , A61K38/1858 , A61K45/06 , C12N15/1138 , C12N2310/11 , A61K2300/00
摘要: Methods and compositions comprising combinations of one or more anti-connexin agents and one or more other agents useful for the promotion and/or improvement of wound healing and/or tissue repair.
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公开(公告)号:WO2009085272A3
公开(公告)日:2010-07-29
申请号:PCT/US2008014023
申请日:2008-12-22
发明人: DUFT BRADFORD J , GREEN COLIN R , BECKER DAVID L
CPC分类号: A61K38/08 , A61K9/0051 , A61K38/10 , A61K38/385 , A61L17/005 , A61L27/54 , A61L31/08 , A61L31/10 , A61L31/16 , A61L2300/25 , A61L2300/252 , A61L2300/258 , A61L2300/432 , A61L2300/602 , A61L2300/606 , A61L2300/608
摘要: Medical devices comprising an anti-connexin agent suitable for introduction into a subject.
摘要翻译: 包含适用于引入受试者的抗连接蛋白药物的医疗装置。
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10.USE OF INHIBITORS OF C0NNEXIN43 FOR TREATMENT OF FIBROTIC CONDITIONS 审中-公开
标题翻译: C0NNEXIN43抑制剂用于治疗纤维状态的用途公开(公告)号:WO2009085270A3
公开(公告)日:2009-09-24
申请号:PCT/US2008014021
申请日:2008-12-22
发明人: BECKER DAVID L , GREEN COLIN R , DUFT BRADFORD J
IPC分类号: A61K31/7088 , A61L15/00 , A61P17/02 , A61P43/00 , C12N15/113
CPC分类号: C12N15/113 , A61K31/7088 , A61K45/06 , A61L15/44 , A61L26/0066 , A61L2300/258 , A61L2300/432 , C12N15/1138 , C12N2310/11 , C12N2310/315
摘要: Treatment of fibrosis and fibrotic diseases, disorders, and conditions, and associated methods, compositions, formulations and articles.
摘要翻译: 纤维化和纤维化疾病,病症和病症以及相关方法,组合物,制剂和制品的治疗。
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