公开(公告)号：WO2012058406A1

公开(公告)日：2012-05-03

申请号：PCT/US2011/058046

申请日：2011-10-27

Applicant: BIAN, Qunzhou ,  CARROLL, John J.

Inventor： BIAN, Qunzhou ,  CARROLL, John J.

IPC: G01N27/62

CPC classification number: G01N27/622 ,  G01N23/00 ,  G06K9/0053 ,  H01J49/0031 ,  H01J49/025 ,  H01J49/04 ,  H01J49/06 ,  H01J49/061

Abstract: Method and systems for managing clear-down are provided. The method can include generating a clear-down trigger associated with an ion mobility spectrometer and operating the ion mobility spectrometer in fast clear-down mode in response to the clear-down trigger. Methods and systems can further provide that where the ion mobility spectrometer operates in fast-switching mode, the ion mobility spectrometer alternating a plurality of times between operation according to a positive ion mode and operation according to a negative ion mode, and further operating according to the positive ion mode for less than about 1 second before switching to the operation according to the negative ion mode, and operating according to the negative ion mode for less than about 1 second before switching to the operation according to the positive ion mode.

Abstract translation: 提供了管理清除的方法和系统。 该方法可以包括产生与离子迁移谱仪相关联的清除触发器，并响应于清除触发而以快速清除模式操作离子迁移谱仪。 方法和系统可进一步提供离子迁移谱仪以快速切换模式工作的方式，离子迁移谱仪根据正离子模式进行操作和根据负离子模式进行操作之间交替多次，并根据 正离子模式小于约1秒，然后根据负离子模式切换到操作，并根据正离子模式切换到操作之前，根据负离子模式操作小于约1秒。

公开(公告)号：WO2012172436A3

公开(公告)日：2012-12-20

申请号：PCT/IB2012/001669

申请日：2012-06-15

Applicant: SMITHS DETECTION MONTREAL INC. ,  LEVIN, Daniel ,  SERGEYEV, Vlad ,  BONDARENKO, Volodimir ,  ATAMANCHUK, Bohdan ,  BIAN, Qunzhou ,  ZALESKI, Henryk ,  PINIARSKI, Mark ,  FELDBERG, Simon ,  JACKSON, Ronald

Inventor： LEVIN, Daniel ,  SERGEYEV, Vlad ,  BONDARENKO, Volodimir ,  ATAMANCHUK, Bohdan ,  BIAN, Qunzhou ,  ZALESKI, Henryk ,  PINIARSKI, Mark ,  FELDBERG, Simon ,  JACKSON, Ronald

IPC: G01N27/68 ,  H01J27/14 ,  H01J49/12 ,  H01J49/40

Abstract: Looped ionization sources for ion mobility spectrometers are described. The ionization sources can be used to ionize molecules from a sample of interest in order to identify the molecules based on the ions. In an implementation, an electrical ionization source includes a wire that is looped between electrical contacts. The wire is used to form a corona responsive to application of voltage between the wire and the walls of an ionization chamber. The corona can form when a sufficient voltage is applied between the wire and the walls. A difference in electrical potential between the wire and a wall forming an ionization chamber, in which wire is contained, can be used to draw the ions away from the wire. In embodiments, the wire can be heated to reduce the voltage used to strike the corona. The ions, subsequently, may ionize the molecules from the sample of interest. The looped corona source can also be used in mass spectrometers (MS).

公开(公告)号：WO2012172436A2

公开(公告)日：2012-12-20

申请号：PCT/IB2012001669

申请日：2012-06-15

Applicant: SMITHS DETECTION MONTREAL INC ,  LEVIN DANIEL ,  SERGEYEV VLAD ,  BONDARENKO VOLODIMIR ,  ATAMANCHUK BOHDAN ,  BIAN QUNZHOU ,  ZALESKI HENRYK ,  PINIARSKI MARK ,  FELDBERG SIMON ,  JACKSON RONALD

Inventor： LEVIN DANIEL ,  SERGEYEV VLAD ,  BONDARENKO VOLODIMIR ,  ATAMANCHUK BOHDAN ,  BIAN QUNZHOU ,  ZALESKI HENRYK ,  PINIARSKI MARK ,  FELDBERG SIMON ,  JACKSON RONALD

IPC: G01N27/68 ,  H01J49/40

CPC classification number: G01N27/622 ,  H01J49/12 ,  H01J49/168

Abstract: Looped ionization sources for ion mobility spectrometers are described. The ionization sources can be used to ionize molecules from a sample of interest in order to identify the molecules based on the ions. In an implementation, an electrical ionization source includes a wire that is looped between electrical contacts. The wire is used to form a corona responsive to application of voltage between the wire and the walls of an ionization chamber. The corona can form when a sufficient voltage is applied between the wire and the walls. A difference in electrical potential between the wire and a wall forming an ionization chamber, in which wire is contained, can be used to draw the ions away from the wire. In embodiments, the wire can be heated to reduce the voltage used to strike the corona. The ions, subsequently, may ionize the molecules from the sample of interest. The looped corona source can also be used in mass spectrometers (MS).

Abstract translation: 描述了用于离子迁移率光谱仪的环形电离源。 电离源可用于从感兴趣的样品中离子化分子，以便基于离子鉴定分子。 在一个实施方案中，电离电离源包括在电触头之间环绕的导线。 导线用于响应于在电线和电离室的壁之间施加电压而形成电晕。 当电线和墙壁之间施加足够的电压时，可以形成电晕。 电线和形成电离室的壁之间的电位差可以用于将离子从电线中拉出。 在实施例中，可以加热导线以降低用于击打电晕的电压。 随后，离子可以使目标样品中的分子离子化。 环状电晕源也可用于质谱仪（MS）。