LIQUID CRYSTAL POLYMERS
    1.
    发明申请
    LIQUID CRYSTAL POLYMERS 审中-公开
    液晶聚合物

    公开(公告)号:WO1997016471A1

    公开(公告)日:1997-05-09

    申请号:PCT/GB1996002650

    申请日:1996-10-31

    IPC分类号: C08G61/00

    摘要: Compounds of formula (I) are provided which may be used in a variety of devices including liquid crystal devices, piezoelectric devices, pyroelectric devices and in optical recording media, wherein X1 and X2 are independently selected from H, CN, COCH3, CO2CH3, m = at least 5; X3 and X4 are independently selected from formula (IA), wherein Y is selected from COO, OCO, O, S, CHOH, CHF, CH2; Q = (CH2)n wherein one or more non-adjacent methylenes may be replaced by O and n = 1-20; Z is selected from O, S, single covalent bond, COO, OCO; when Y is CH2 then n may also be 0; formula (A) represents any mesogenic group; X3 and X4 are also independently selected from H, OH, OCOR , COOH, CO2R , (CH2)pOH, (CH2)pCO2H, -(CH2)pOR or -(CH2)pCO2R and p = 1-20, R = H or C1-16alkyl, when R = C2-16alkyl the terminal CH3 group may be replaced by Br or Cl; provided that at least one of X3 and X4 is selected from formula (IA).

    摘要翻译: 提供式(I)化合物,其可用于包括液晶装置,压电装置,热电装置和光学记录介质的各种装置中,其中X 1和X 2独立地选自H,CN,COCH 3,CO 2 CH 3,m =至少5; X 3和X 4独立地选自式(IA),其中Y选自COO,OCO,O,S,CHOH,CHF,CH 2; Q =(CH 2)n,其中一个或多个不相邻亚甲基可被O代替,n = 1-20; Z选自O,S,单共价键,COO,OCO; 当Y是CH2时,n也可以是0; 式(A)表示任何介晶组; X和X 4还独立地选自H,OH,OCOR 1,COOH,CO 2 R 1,(CH 2)p OH,(CH 2)p CO 2 H, - (CH 2)pOR 1或 - (CH 2)p CO 2 R 1 >和p = 1-20,R 1 = H或C 1-6烷基,当R 1 = C 2-6-16烷基时,末端CH 3基团可被Br或Cl取代; 条件是X3和X4中的至少一个选自式(IA)。

    LIQUID CRYSTAL POLYMERS
    2.
    发明申请
    LIQUID CRYSTAL POLYMERS 审中-公开
    液晶聚合物

    公开(公告)号:WO1998008918A1

    公开(公告)日:1998-03-05

    申请号:PCT/GB1997002225

    申请日:1997-08-20

    IPC分类号: C09K19/38

    摘要: Methods, based on the Wittig-Horner reaction, are provided for the synthesis of compounds of formula (I) wherein m is from 5-150, X and Y are independently selected from: CN, H, OH, COCH3, CO2H, CO2R1, where R1 is C1-12alkyl, NCS, SCN, CF3, CH2X where X is F, Cl, Br, OH, CHF2 and formula (IB), wherein J for each X and Y group is independently selected from: CH2, single covalent bond, OOC, CO2, O, CH2O, OCH2, CH2CO2, CH2OOC; p = 1-20; L for each X and Y group is independently selected from: O, CH2, OCO, CO2, S, NH; (a) is defined by formula (IC), wherein rings A, B and C are independently selected from phenyl, cyclohexyl, pyridine and pyrimidine and may be independently of each other substituted with at least one of Cl or F; linking groups A and B may be selected from single bond, CO2, OOC, CH2O, OCH2, CH2CH2, CC; Z is selected from CN, F, Cl, NO2, R, OR, CO2R, CF3, OOCR, NCS, SCN, where R = straight chain or branched chain alkyl and may include from 1-16 carbon atoms and including where one or more non-adjacent CH2 groups may be substituted by CH(CN), CH(CF3), CH(Cl), CH(CH3) in chiral or non-chiral form; provided that at least one of X and Y is selected from (IB); said method comprising the polymerisation of general formula (II), wherein X and Y are as defined for formula (I).

    摘要翻译: 提供了基于Wittig-Horner反应的合成式(I)化合物,其中m为5-150,X和Y独立地选自:CN,H,OH,COCH 3,CO 2 H,CO 2 R 1, 其中R1是C1-12烷基,NCS,SCN,CF3,CH2X,其中X是F,Cl,Br,OH,CHF2和式(IB),其中每个X和Y基团的J独立地选自:CH 2,单共价键 ,OOC,CO 2,O,CH 2 O,OCH 2,CH 2 CO 2,CH 2 OOC; p = 1-20; 每个X和Y基团的L独立地选自:O,CH 2,OCO,CO 2,S,NH; (a)由式(IC)定义,其中环A,B和C独立地选自苯基,环己基,吡啶和嘧啶,并且可以彼此独立地被Cl或F中的至少一个取代; 连接基团A和B可以选自单键,CO 2,OOC,CH 2 O,OCH 2,CH 2 CH 2,CC; Z选自CN,F,Cl,NO 2,R,OR,CO 2 R,CF 3,OOCR,NCS,SCN,其中R =直链或支链烷基,并且可以包括1-16个碳原子,并且包括其中一个或多个 不相邻的CH2基可以被手性或非手性形式的CH(CN),CH(CF 3),CH(Cl),CH(CH 3)取代; 条件是X和Y中的至少一个选自(IB); 所述方法包括通式(II)的聚合,其中X和Y如式(I)所定义。

    USE OF POLY(DIALLYLAMINE) POLYMERS
    3.
    发明申请
    USE OF POLY(DIALLYLAMINE) POLYMERS 审中-公开
    使用聚(二甲苯胺)聚合物

    公开(公告)号:WO0136510A2

    公开(公告)日:2001-05-25

    申请号:PCT/GB0004308

    申请日:2000-11-10

    摘要: The invention provides a poly(diallylamine) polymer derived from a monomer of formula (I) wherein R is a bridging group of valency r and r is an integer of 3 or greater, or a pharmaceutically acceptable derivative of such a polymer, for use in any surgical, therapeutic or diagnostic method, in particular for use as a bile acid remover and/or for use in reducing serum cholesterol levels. The invention also provides the use of such a polymer or derivative in the preparation of a medicament for use in any surgical, therapeutic or diagnostic method, in particular where the medicament is a bile acid remover or is for use in reducing serum cholesterol levels. The invention further provides a method of treatment of a human or animal patient to reduce levels of bile acid and/or serum cholesterol, by administering such a polymer; a pharmaceutical composition containing the polymer; and a method for producing the pharmaceutical composition.

    摘要翻译: 本发明提供衍生自式(I)的单体的聚(二烯丙基胺)聚合物,其中R 6是价态r的桥连基团,r是3或更大的整数,或这种聚合物的药学上可接受的衍生物, 用于任何手术,治疗或诊断方法,特别是用作胆汁酸去除剂和/或用于降低血清胆固醇水平。 本发明还提供了这种聚合物或衍生物在制备用于任何手术,治疗或诊断方法的药物中的用途,特别是其中药物是胆汁酸去除剂或用于降低血清胆固醇水平的药物。 本发明还提供了通过施用这种聚合物来治疗人或动物患者以降低胆汁酸和/或血清胆固醇水平的方法; 含有聚合物的药物组合物; 以及该药物组合物的制造方法。

    LIQUID CRYSTAL POLYMERS
    5.
    发明申请
    LIQUID CRYSTAL POLYMERS 审中-公开
    液晶聚合物

    公开(公告)号:WO1997016472A1

    公开(公告)日:1997-05-09

    申请号:PCT/GB1996002655

    申请日:1996-10-31

    IPC分类号: C08G61/00

    摘要: Compounds of formula (I) are provided which may be used in a variety of devices including liquid crystal devices, piezoelectric devices, pyroelectric devices and in optical recording media; in said formula n = at least 5; Rx, Ry, Rz are independently selected from formula (IA), wherein Y is selected from COO, OCO, O, S, CHOH, CHF, CH2; Q = (CH2)n wherein one or more non-adjacent methylenes may be replaced by O and n = 1 - 20; Z is selected from O, S, single covalent bond, COO, OCO; when Y is CH2 then n may also be 0; (IB) represents any mesogenic group; Rx, Ry, Rz are also independently selected from H, OH, OCOR , COOH, CO2R , (CH2)pOH, (CH2)pCO2H, -(CH2)pOR or -(CH2)pCO2R and p = 1 - 20, R = H or C1-16 alkyl; when R = C2-16 alkyl the terminal CH3 group may be replaced by Br or Cl; provided that at least one of Rx, Ry, Rz is selected from formula (IA).

    摘要翻译: 提供式(I)化合物,其可用于包括液晶装置,压电装置,热电装置和光学记录介质的各种装置中; 在所述式中n =至少5; Rx,Ry,Rz独立地选自式(IA),其中Y选自COO,OCO,O,S,CHOH,CHF,CH 2; Q =(CH 2)n,其中一个或多个不相邻的亚甲基可被O代替,n = 1-20; Z选自O,S,单共价键,COO,OCO; 当Y是CH2时,n也可以是0; (IB)代表任何介晶组; Rx,Ry,Rz也独立地选自H,OH,OCOR 1,COOH,CO 2 R 1,(CH 2)p OH,(CH 2)p CO 2 H, - (CH 2)pOR 1或 - (CH 2)p CO 2 R 1和p = 1-20,R 1 = H或C 1-6烷基; 当R 1 = C2-16烷基时,末端CH 3基团可被Br或Cl取代; 条件是Rx,Ry,Rz中的至少一个选自式(IA)。

    REDOX POLYMERISATION COATING PROCESS
    10.
    发明申请
    REDOX POLYMERISATION COATING PROCESS 审中-公开
    REDOX聚合涂层工艺

    公开(公告)号:WO1995001402A1

    公开(公告)日:1995-01-12

    申请号:PCT/GB1994001275

    申请日:1994-06-14

    IPC分类号: C09D04/06

    CPC分类号: C08F271/00

    摘要: Coated solids, for example suitable for use as the dispersed phase of an electrorheological fluid, are prepared by effecting polymerisation of at least one coating monomer in the presence of surfaces of a polymer capable itself of acting as the redox initiator for the polymerisation of the monomer.

    摘要翻译: 涂覆的固体,例如适合用作电粘滞性流体的分散相,通过在本身可以用作聚合单体的氧化还原引发剂的聚合物的表面的存在下进行至少一种涂料单体的聚合来制备 。