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公开(公告)号：WO2007087549A2
公开(公告)日：2007-08-02
申请号：PCT/US2007/060939
申请日：2007-01-24
Applicant: SMITHKLINE BEECHAM CORPORATION , GUDMUNDSSON, Kristjan , BOGGS, Sharon, Davis , MILLER, John, Franklin , SVOLTO, Angilique, Christina
Inventor： GUDMUNDSSON, Kristjan , BOGGS, Sharon, Davis , MILLER, John, Franklin , SVOLTO, Angilique, Christina
IPC: A61K31/4745
CPC classification number: C07D471/04 , C07D519/00
Abstract: The present invention provides compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind to chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 of a target cell.
Abstract translation: 本发明提供了以与趋化因子受体结合并且影响天然配体或趋化因子与受体如CXCR4的结合的方式证明对来自HIV感染的靶细胞具有保护作用的化合物 的目标细胞。
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公开(公告)号：WO2006036816A3
公开(公告)日：2006-06-15
申请号：PCT/US2005034218
申请日：2005-09-23
Applicant: SMITHKLINE BEECHAM CORP , GUDMUNDSSON KRISTJAN , BOGGS SHARON DAVIS
Inventor： GUDMUNDSSON KRISTJAN , BOGGS SHARON DAVIS
IPC: A61K31/44 , C07D471/02
CPC classification number: C07D471/04
Abstract: The present invention provides novel compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind specifically to the chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 and/or CCR5 of a target cell.
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公开(公告)号：WO2005005386A1
公开(公告)日：2005-01-20
申请号：PCT/US2004/018180
申请日：2004-06-07
Inventor： BOGGS, Sharon, Davis , GUDMUNDSSON, Kristjan
IPC: C07D209/82
CPC classification number: C07D401/12 , C07D209/88 , C07D403/12
Abstract: The present invention relates to novel compounds of formula (I), that are useful in the treatment of human papillomaviruses, and also to the methods for the making and use of such compounds.
Abstract translation: 本发明涉及可用于治疗人乳头状瘤病毒的新型式（I）化合物，以及制备和使用这些化合物的方法。
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公开(公告)号：WO2004009091A8
公开(公告)日：2004-12-29
申请号：PCT/US0316016
申请日：2003-05-20
Applicant: GLAXO GROUP LTD , BOGGS SHARON , COLLINS JON L , FIVUSH ADAM , STEWART EUGENE LEE , WILLSON TIMOTHY MARK
Inventor： BOGGS SHARON , COLLINS JON L , FIVUSH ADAM , STEWART EUGENE LEE , WILLSON TIMOTHY MARK
IPC: C07D473/06 , A61K31/52 , A61K31/522 , A61K31/5377 , A61K31/541 , A61K31/55 , A61P3/06 , A61P9/00 , A61P9/10 , A61P43/00 , C07D473/04 , C07D473/08 , C07D273/04
CPC classification number: A61K31/522 , A61K31/52 , A61K31/675 , C07D473/04 , C07D473/06
Abstract: The invention relates to methods for the treatment or prevention of an LXR mediated disease or condition, including cariovascular disease and atherosclerosis, novel compounds for use in such methods and pharmaceutical compositions comprising compounds for use in such methods.
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公开(公告)号：WO2007087549A3
公开(公告)日：2007-12-13
申请号：PCT/US2007060939
申请日：2007-01-24
Applicant: SMITHKLINE BEECHAM CORP , GUDMUNDSSON KRISTJAN , BOGGS SHARON DAVIS , MILLER JOHN FRANKLIN , SVOLTO ANGILIQUE CHRISTINA
Inventor： GUDMUNDSSON KRISTJAN , BOGGS SHARON DAVIS , MILLER JOHN FRANKLIN , SVOLTO ANGILIQUE CHRISTINA
IPC: C07D491/00
CPC classification number: C07D471/04 , C07D519/00
Abstract: The present invention provides compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind to chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 of a target cell.
Abstract translation: 本发明提供了以与趋化因子受体结合并且影响天然配体或趋化因子与靶细胞的受体如CXCR4的结合的方式证明对来自HIV感染的靶细胞具有保护作用的化合物。
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Patent Agency Ranking
公开(公告)号：WO2006028896A3
公开(公告)日：2006-04-27
申请号：PCT/US2005031098
申请日：2005-08-31
Applicant: SMITHKLINE BEECHAM CORP , GUDMUNDSSON KRISTJAN , BOGGS SHARON DAVIS
Inventor： GUDMUNDSSON KRISTJAN , BOGGS SHARON DAVIS
IPC: A61K31/44 , A61K31/47 , C07D215/38 , C07D471/02
CPC classification number: C07D471/04
Abstract: The present invention provides novel compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind specifically to the chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 and/or CCR5 of a target cell.
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公开(公告)号：WO2006028896A2
公开(公告)日：2006-03-16
申请号：PCT/US2005/031098
申请日：2005-08-31
Inventor： GUDMUNDSSON, Kristjan , BOGGS, Sharon, Davis
IPC: C07D403/02
CPC classification number: C07D471/04
Abstract: The present invention provides novel compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind specifically to the chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 and/or CCR5 of a target cell.
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公开(公告)号：WO2004048349A1
公开(公告)日：2004-06-10
申请号：PCT/US2003/035808
申请日：2003-11-12
Applicant: SMITHKLINE BEECHAM CORPORATION , BOGGS, Sharon, D. , COLLINS, Jon, L. , HYATT, Stephen, M. , MALONEY, Patrick, R.
Inventor： BOGGS, Sharon, D. , COLLINS, Jon, L. , HYATT, Stephen, M. , MALONEY, Patrick, R.
IPC: C07D261/08
CPC classification number: C07D261/08 , C07D413/12 , C07D417/12
Abstract: The invention relates to a compound of formula (I) useful as an agonist for FXR: wherein all variables are as defined herein and to pharmaceutical compositions, methods of using, and processes for preparing the same.
Abstract translation: 本发明涉及可用作FXR激动剂的式（I）化合物：其中所有变量如本文所定义，以及药物组合物，使用方法及其制备方法。
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公开(公告)号：WO2007027999A3
公开(公告)日：2007-03-08
申请号：PCT/US2006/034195
申请日：2006-08-30
Inventor： GUDMUNDSSON, Kristjan , BOGGS, Sharon, Davis
IPC: C07D215/38 , C07D215/14
Abstract: The present invention provides compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind to chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 of a target cell.
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公开(公告)号：WO2007027999A2
公开(公告)日：2007-03-08
申请号：PCT/US2006034195
申请日：2006-08-30
Applicant: SMITHKLINE BEECHAM CORP , GUDMUNDSSON KRISTJAN , BOGGS SHARON DAVIS
Inventor： GUDMUNDSSON KRISTJAN , BOGGS SHARON DAVIS
IPC: A61K31/4745
CPC classification number: C07D471/04
Abstract: The present invention provides compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind to chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 of a target cell.
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