公开(公告)号：WO2012111995A1

公开(公告)日：2012-08-23

申请号：PCT/KR2012/001185

申请日：2012-02-16

Applicant: LG LIFE SCIENCES LTD. ,  KIM, Young Kwan ,  JOO, Hyun Woo ,  KIM, Myoung Yeol ,  PARK, Heui Sul ,  LEE, Tae Hee ,  KWAK, Hyo Shin ,  SHIM, Dong Sup ,  CHOI, Eun Sil

Inventor： KIM, Young Kwan ,  JOO, Hyun Woo ,  KIM, Myoung Yeol ,  PARK, Heui Sul ,  LEE, Tae Hee ,  KWAK, Hyo Shin ,  SHIM, Dong Sup ,  CHOI, Eun Sil

IPC: C07D401/14 ,  C07D401/12 ,  A61K31/4523 ,  A61P3/00

CPC classification number: C07D451/06 ,  C07D211/46 ,  C07D401/04 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D413/04 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14

Abstract: The present invention relates to oxime derivatives, a method for preparing the same, a pharmaceutical composition comprising the same and use thereof. The oxime derivatives according to the present invention act as GPR119 agonists to stimulate the secretion of insulin and promote GLP-1 formation for preventing or treating type 2 diabetes, complications of diabetes, obesity, dyslipidemia or osteoporosis.

Abstract translation: 本发明涉及肟衍生物，其制备方法，包含其的药物组合物及其应用。 根据本发明的肟衍生物用作GPR119激动剂以刺激胰岛素的分泌并促进用于预防或治疗2型糖尿病，糖尿病并发症，肥胖症，血脂异常或骨质疏松症的GLP-1形成。

公开(公告)号：WO2011043568A3

公开(公告)日：2011-09-29

申请号：PCT/KR2010006760

申请日：2010-10-04

Applicant: LG LIFE SCIENCES LTD ,  SONG JEONG UK ,  KIM GEUN TAE ,  CHOI SUNG PIL ,  JUNG CHEOL KYU ,  PARK DEOK SEONG ,  CHOI EUN SIL ,  KIM TAE HUN ,  PARK HYUN JUNG ,  PARK WAN SU ,  PARK HEUI SUL ,  KOO KI CHUL ,  ARTEMOV VASILY

Inventor： SONG JEONG UK ,  KIM GEUN TAE ,  CHOI SUNG PIL ,  JUNG CHEOL KYU ,  PARK DEOK SEONG ,  CHOI EUN SIL ,  KIM TAE HUN ,  PARK HYUN JUNG ,  PARK WAN SU ,  PARK HEUI SUL ,  KOO KI CHUL ,  ARTEMOV VASILY

IPC: C07D403/02 ,  A61K31/40 ,  A61P3/10 ,  C07D209/04

CPC classification number: C07D403/04 ,  C07D401/04 ,  C07D405/14 ,  C07D409/04

Abstract: The present invention relates to novel compounds which are effective as an inhibitor for xanthine oxidase, a process for preparing the same, and a pharmaceutical composition comprising a therapeutically effective amount of the same.

Abstract translation: 本发明涉及作为黄嘌呤氧化酶抑制剂有效的新化合物，其制备方法以及包含治疗有效量的药物组合物。

公开(公告)号：WO2011043568A2

公开(公告)日：2011-04-14

申请号：PCT/KR2010/006760

申请日：2010-10-04

Applicant: LG LIFE SCIENCES LTD. ,  SONG, Jeong Uk ,  KIM, Geun Tae ,  CHOI, Sung Pil ,  JUNG, Cheol Kyu ,  PARK, Deok Seong ,  CHOI, Eun Sil ,  KIM, Tae Hun ,  PARK, Hyun Jung ,  PARK, Wan Su ,  PARK, Heui Sul ,  KOO, Ki Chul ,  ARTEMOV, Vasily

Inventor： SONG, Jeong Uk ,  KIM, Geun Tae ,  CHOI, Sung Pil ,  JUNG, Cheol Kyu ,  PARK, Deok Seong ,  CHOI, Eun Sil ,  KIM, Tae Hun ,  PARK, Hyun Jung ,  PARK, Wan Su ,  PARK, Heui Sul ,  KOO, Ki Chul ,  ARTEMOV, Vasily

IPC: C07D403/02 ,  C07D209/04 ,  A61K31/40 ,  A61P3/10

CPC classification number: C07D403/04 ,  C07D401/04 ,  C07D405/14 ,  C07D409/04

Abstract: The present invention relates to novel compounds which are effective as an inhibitor for xanthine oxidase, a process for preparing the same, and a pharmaceutical composition comprising a therapeutically effective amount of the same.

Abstract translation: 本发明涉及作为黄嘌呤氧化酶抑制剂有效的新化合物，其制备方法和含有治疗有效量的药物组合物。