公开(公告)号：WO2012149145A9

公开(公告)日：2013-02-21

申请号：PCT/US2012035193

申请日：2012-04-26

Applicant: ADLYFE INC ,  FEUERSTEIN GIORA ,  CLIFF RICHARD

Inventor： FEUERSTEIN GIORA ,  CLIFF RICHARD

IPC: G01N33/68 ,  A61B5/00

CPC classification number: A61K49/0056 ,  A61B3/12 ,  A61B5/4088 ,  A61K49/0021 ,  A61K49/006 ,  G01N33/6896 ,  G01N2800/2821

Abstract: Described are methods for the detection, in the eye of an individual, of protein aggregates or other misfolded proteins associated with disease using peptide or peptide mimic probes that preferentially associate with the protein aggregates or misfolded proteins, which can be accomplished non-invasively.

Abstract translation: 描述了用个体眼睛检测蛋白质聚集体或与疾病相关的其他错误折叠蛋白质的方法，所述蛋白质使用肽或肽模拟物探针优先与蛋白质聚集体或错误折叠的蛋白质相关联，这可以非侵入性地完成。

公开(公告)号：WO2012149145A3

公开(公告)日：2013-01-10

申请号：PCT/US2012035193

申请日：2012-04-26

Applicant: ADLYFE INC ,  FEUERSTEIN GIORA ,  CLIFF RICHARD

Inventor： FEUERSTEIN GIORA ,  CLIFF RICHARD

IPC: G01N33/68 ,  A61B5/00

CPC classification number: A61K49/0056 ,  A61B3/12 ,  A61B5/4088 ,  A61K49/0021 ,  A61K49/006 ,  G01N33/6896 ,  G01N2800/2821

Abstract: Described are methods for the detection, in the eye of an individual, of protein aggregates or other misfolded proteins associated with disease using peptide or peptide mimic probes that preferentially associate with the protein aggregates or misfolded proteins, which can be accomplished non-invasively.

Abstract translation: 描述了使用可以非侵入性地完成蛋白质聚集体或错误折叠的蛋白质的肽或肽模拟物探针来检测个体眼睛中的蛋白质聚集体或与疾病相关的其他错误折叠的蛋白质的方法。

公开(公告)号：WO2010126679A2

公开(公告)日：2010-11-04

申请号：PCT/US2010/029860

申请日：2010-04-02

Applicant: ALTERA CORPORATION ,  WORTMAN, Curt ,  LEE, Chong, H. ,  CLIFF, Richard, G.

Inventor： WORTMAN, Curt ,  LEE, Chong, H. ,  CLIFF, Richard, G.

IPC: G11C7/00 ,  G11C5/02 ,  G06F15/76

CPC classification number: G06F17/5045 ,  G06F2217/84 ,  H03K19/17724 ,  H03K19/17732

Abstract: An integrated circuit (IC) is provided. The IC includes a first region having an array of programmable logic cells. The IC also includes a second region incorporated into the IC and in communication with the first region. The second region includes standard logic cells and base cells. In one embodiment, the standard logic cells are assembled or interconnected to accommodate known protocols. The base cells include configurable logic to adapt to modifications to emerging communication protocols, which are supported by the base cells. The second region can be embedded in the first region in one embodiment. In another embodiment, the second region is defined around a perimeter of the first region. The configurable logic may be composed of hybrid logic elements that have metal mask programmable interconnections so that as emerging communication protocols evolve and are modified, the IC can be modified to accommodate to the changes in the protocol. In another embodiment, a generic device can be customized by replacing the original function with a completely new function targeting a specific application space, e.g., replacing the original function such as a PCI Express, used for computing based applications, with 4OG /10OG Ethernet and Interlaken, used in wireline applications. A method of designing an integrated circuit is also provided.

Abstract translation: 提供集成电路（IC）。 IC包括具有可编程逻辑单元阵列的第一区域。 IC还包括结合到IC中并与第一区域通信的第二区域。 第二区包括标准逻辑单元和基本单元。 在一个实施例中，标准逻辑单元被组合或互连以适应已知协议。 基本单元包括可配置逻辑以适应由基本单元支持的新兴通信协议的修改。 在一个实施例中，第二区域可以嵌入第一区域。 在另一个实施例中，第二区域围绕第一区域的周边限定。 可配置逻辑可以由具有金属掩模可编程互连的混合逻辑元件组成，使得随着新兴通信协议的发展和修改，可以修改IC以适应协议的改变。 在另一个实施例中，可以通过用针对特定应用空间的全新功能替换原始功能来定制通用设备，例如用4OG / 10OG以太网替换用于基于计算的应用的诸如PCI Express的原始功能，例如PCI Express， 因特拉肯，用于有线应用。 还提供了一种设计集成电路的方法。

公开(公告)号：WO2012149145A2

公开(公告)日：2012-11-01

申请号：PCT/US2012/035193

申请日：2012-04-26

Applicant: ADLYFE, INC. ,  FEUERSTEIN, Giora ,  CLIFF, Richard

Inventor： FEUERSTEIN, Giora ,  CLIFF, Richard

IPC: A61K49/00

CPC classification number: A61K49/0056 ,  A61B3/12 ,  A61B5/4088 ,  A61K49/0021 ,  A61K49/006 ,  G01N33/6896 ,  G01N2800/2821

Abstract: Described are methods for the detection, in the eye of an individual, of protein aggregates or other misfolded proteins associated with disease using peptide or peptide mimic probes that preferentially associate with the protein aggregates or misfolded proteins, which can be accomplished non-invasively.

Abstract translation: 描述了使用可以非侵入性地完成蛋白质聚集体或错误折叠的蛋白质的肽或肽模拟物探针来检测个体眼睛中的蛋白质聚集体或与疾病相关的其他错误折叠的蛋白质的方法。

公开(公告)号：WO2010126679A3

公开(公告)日：2011-01-13

申请号：PCT/US2010029860

申请日：2010-04-02

Applicant: ALTERA CORP ,  WORTMAN CURT ,  LEE CHONG H ,  CLIFF RICHARD G

Inventor： WORTMAN CURT ,  LEE CHONG H ,  CLIFF RICHARD G

IPC: G11C7/00 ,  G06F15/76 ,  G11C5/02

CPC classification number: G06F17/5045 ,  G06F2217/84 ,  H03K19/17724 ,  H03K19/17732

Abstract: An integrated circuit (IC) is provided. The IC includes a first region having an array of programmable logic cells. The IC also includes a second region incorporated into the IC and in communication with the first region. The second region includes standard logic cells and base cells. In one embodiment, the standard logic cells are assembled or interconnected to accommodate known protocols. The base cells include configurable logic to adapt to modifications to emerging communication protocols, which are supported by the base cells. The second region can be embedded in the first region in one embodiment. In another embodiment, the second region is defined around a perimeter of the first region. The configurable logic may be composed of hybrid logic elements that have metal mask programmable interconnections so that as emerging communication protocols evolve and are modified, the IC can be modified to accommodate to the changes in the protocol. In another embodiment, a generic device can be customized by replacing the original function with a completely new function targeting a specific application space, e.g., replacing the original function such as a PCI Express, used for computing based applications, with 4OG /10OG Ethernet and Interlaken, used in wireline applications. A method of designing an integrated circuit is also provided.

Abstract translation: 提供集成电路（IC）。 IC包括具有可编程逻辑单元阵列的第一区域。 IC还包括结合到IC中并与第一区域通信的第二区域。 第二区包括标准逻辑单元和基本单元。 在一个实施例中，标准逻辑单元被组合或互连以适应已知协议。 基本单元包括可配置逻辑以适应由基本单元支持的新兴通信协议的修改。 在一个实施例中，第二区域可以嵌入第一区域。 在另一个实施例中，第二区域围绕第一区域的周边限定。 可配置逻辑可以由具有金属掩模可编程互连的混合逻辑元件组成，使得随着新兴通信协议的发展和修改，可以修改IC以适应协议的改变。 在另一个实施例中，可以通过用针对特定应用空间的全新功能替换原始功能来定制通用设备，例如用4OG / 10OG以太网替换用于基于计算的应用的诸如PCI Express的原始功能，例如PCI Express， 因特拉肯，用于有线应用。 还提供了一种设计集成电路的方法。