公开(公告)号：WO2008124841A2

公开(公告)日：2008-10-16

申请号：PCT/US2008/059940

申请日：2008-04-10

Applicant: C. R. BARD, INC. ,  COHEN, Ben ,  ROBLES, Dylan K. ,  MESSERLY, Shayne ,  BURNSIDE, Eddie K.

Inventor： COHEN, Ben ,  ROBLES, Dylan K. ,  MESSERLY, Shayne ,  BURNSIDE, Eddie K.

IPC: G01S7/52 ,  G01S15/89

CPC classification number: A61B8/145 ,  A61B8/4472 ,  A61B8/4483 ,  A61B8/461 ,  A61B8/5207 ,  A61B8/56 ,  G01S7/003 ,  G01S7/52017 ,  G01S7/5208 ,  G01S7/52082 ,  G01S7/52085 ,  G01S7/52096 ,  G01S15/8909

Abstract: A low power ultrasound system for use in sonography applications, including vascular imaging, is disclosed. In one embodiment, the low power ultrasound system comprises a base unit that includes an image processor and a display. An ultrasound probe is operably connected to the base unit. The probe includes a head portion including an array of crystal transducers. A plurality of pulser/receiver modules that cause the transducers to emit ultrasonic transmit pulses are also included in the probe. The pulser/receiver modules are further configured to receive analog signals relating to ultrasonic echo receive pulses detected by the transducers. The probe includes a singular low noise amplifier that amplifies the analog signals, and an analog-to-digital converter that converts the analog signals to a digital signal. A wireless interface is included for enabling the digital signal to be wirelessly transmitted from the probe to the image processor of the base unit.

Abstract translation: 公开了一种用于超声波应用的低功率超声系统，包括血管成像。 在一个实施例中，低功率超声系统包括包括图像处理器和显示器的基本单元。 超声探头可操作地连接到基座单元。 探头包括包括晶体换能器阵列的头部。 导致换能器发射超声波发射脉冲的多个脉冲发生器/接收器模块也包括在探头中。 脉冲发生器/接收器模块还被配置为接收与由换能器检测到的超声回波接收脉冲有关的模拟信号。 该探头包括放大模拟信号的单个低噪声放大器，以及将模拟信号转换为数字信号的模数转换器。 包括无线接口，用于使数字信号从探头无线传输到基本单元的图像处理器。

公开(公告)号：WO2004013009A1

公开(公告)日：2004-02-12

申请号：PCT/US2003/024484

申请日：2003-08-06

Applicant: COHEN, Ben, Z. ,  KELLY, Nigel

Inventor： KELLY, Nigel

IPC: B65D37/00

CPC classification number: B65D47/18 ,  A61F9/0008 ,  B65D1/32 ,  B65D23/00 ,  B65D23/001

Abstract: To overcome shortcomings of the prior art, the subject invention is provided which includes various dropper bottle designs and dropper bottle assemblies including accessories for dropper bottles. More specifically, certain embodiments use devices (10, 300) to restrict the amount the dropper bottle (12) is deformed in administering a dose; other embodiments rely on mechanical reduction of interior volume (without deformation of the dropper bottle (12) to administer a dose, such as with a displaceable piston (500, 602); and, yet, a further embodiment provides a valuing arrangement (402, 404) to limit a dose. Features (200) are also included which aid in the alignment of the dropper bottle's nozzle to the eye, and a feature (102) is provided for protecting the user's eye from potential damage which can occur if a pointed nozzle (104) is brought into contact with the eye during alignment.

Abstract translation: 为了克服现有技术的缺点，提供了本发明，其包括各种滴管瓶设计和滴管瓶组件，其包括用于滴瓶的附件。 更具体地，某些实施例使用装置（10,300）来限制滴管瓶（12）施用剂量时变形的量; 其他实施例依赖于内部容积的机械减小（没有变形的滴管瓶（12））来施加剂量，例如用可移动的活塞（500,602）;并且，另一实施例提供了一种估值装置 还包括特征（200），其有助于将滴管瓶的喷嘴对准眼睛，并且提供特征（102），用于保护使用者的眼睛免受潜在的损害，如果指尖 喷嘴（104）在对准期间与眼睛接触。

公开(公告)号：WO2013138466A1

公开(公告)日：2013-09-19

申请号：PCT/US2013/030882

申请日：2013-03-13

Applicant: COHEN, Ben, Z.

Inventor： PARUNAK, Gene ,  MARTINEAU, Robert, C. ,  MUNSINGER, Aaron, J.

IPC: B65D47/18

CPC classification number: A61F9/0008 ,  B05B1/06 ,  B05B1/28 ,  B05B1/30 ,  B05B1/34 ,  B65D47/18

Abstract: A nozzle is provided herein for ophthalmic dispensers which is configured to accommodate microdosing. The nozzle includes a converging pathway. Preferably, the pathway converges so as to impart momentum to liquid passing therethrough through an increase of velocity. A tapered portion may be provided flared openly from the inlet to best accept liquid flow thereinto and provide a funneling effect into the flowpath. Preferably, the flowpath terminates at an outlet which is internally un-radiused and circumscribed by a chamfered surface.

Abstract translation: 本文提供了一种用于眼科分配器的喷嘴，其配置成适应微量。 喷嘴包括会聚路径。 优选地，路径会收敛，以便通过速度的增加使液体通过其中的动量。 锥形部分可以被设置成从入口开口膨胀，以最好地接受液体流入其中并且向流路提供漏斗效应。 优选地，流动路径终止于内部未被倒角并由倒角表面限定的出口。

公开(公告)号：WO03024823A9

公开(公告)日：2004-05-06

申请号：PCT/US0229892

申请日：2002-09-20

Applicant: COHEN BEN Z ,  KELLY NIGEL B

Inventor： COHEN BEN Z ,  KELLY NIGEL B

IPC: B05B11/00 ,  B67D7/60 ,  B65D35/28 ,  A61M5/00 ,  A62C13/62 ,  B67D5/42 ,  F02M47/02

CPC classification number: B05B11/3052 ,  B05B11/0027 ,  B05B11/3001 ,  B05B11/3023 ,  B05B11/3054 ,  B05B11/3059

Abstract: Several different features are provided for use with a pump, particularly a microdispensing pump. In a first aspect of the subject invention, latch fingers (30) are provided which coact with a stop member (46) to yieldingly inhibit movement of an actuator (38) of the pump (10) to ensure sufficient momentum. is provided to the pump for actuation. In a second aspect of the invention, an overcap (52) is provided which defines an at least liquid-tight seal with the pump body at locations spaced from a nozzle (21) of the pump to limit ingress of contaminants into the nozzle. In a third aspect, at least one protruding bead (58) is provided in proximity to at least one edge of a label mounted to the pump body to restrict removal thereof. In a fourth aspect, at least one rib (72) is provided in proximity to a dispensing cap (16) to provide lateral stability thereto.

Abstract translation: 提供了与泵，特别是微型分配泵一起使用的若干不同特征。 在本发明的第一方面，提供了与止动构件（46）共同作用的闩锁指（30），以有效地阻止泵（10）的致动器（38）的运动，以确保足够的动量。 被提供到泵用于致动。 在本发明的第二方面，提供了一种顶盖（52），其在与泵的喷嘴（21）间隔开的位置处限定至少液密密封，以限制污染物进入喷嘴的入口。 在第三方面中，至少一个突出的凸缘（58）设置在安装到泵体的标签的至少一个边缘附近以限制其移除。 在第四方面，至少一个肋（72）设置在靠近分配帽（16）处以向其提供侧向稳定性。

公开(公告)号：WO2003099706A1

公开(公告)日：2003-12-04

申请号：PCT/US2003/015119

申请日：2003-05-14

Applicant: COHEN, Ben, Z. ,  SCHULTZ, Robert, S.

Inventor： SCHULTZ, Robert, S.

IPC: B67D5/42

CPC classification number: B05B11/3018 ,  B05B1/3436 ,  B05B11/0048 ,  B05B11/0067 ,  B05B11/0072 ,  B05B11/0075 ,  B05B11/3001 ,  B05B11/3016

Abstract: Pump system provided with either a valve stem (42 or a piston (42’), either having a constant-diameter stroke portion (82, 116) interposed between reduced-diameter portions. At least one stationary sealing member (32, 32’) immovably affixed to a pump body (14, 14’) is also provided formed to sealingly engage the stroke portion of the valve stem or the piston. The sealing member is also formed to not engage the reduced-diameter portions. As such, the volume of the administered dose is controlled by the stroke length, which, in turn, is a function of the dimensioning of the constant-diameter stroke portion and the dimensioning of the sealing member. Advantageously, with the subject invention, a minimal number of tolerances can be implicated in controlling dosing volume.

Abstract translation: 具有阀杆（42或活塞（42'））的泵系统，其具有插入在直径减小部分之间的恒定直径行程部分（82,116），至少一个固定密封构件（32,32'） 不可移动地固定在泵体（14,14'）上也形成为密封地接合阀杆或活塞的行程部分，密封部件也形成为不与缩径部接合，因此， 施用剂量的控制由行程长度控制，这又是恒定直径行程部分的尺寸和密封构件的尺寸的函数。有利地，根据本发明，最小数量的公差可以 涉及控制剂量。

公开(公告)号：WO2002094708A1

公开(公告)日：2002-11-28

申请号：PCT/US2002/016539

申请日：2002-05-23

Applicant: COHEN, Ben, Z. ,  SCHULTZ, Robert, S.

Inventor： SCHULTZ, Robert, S.

IPC: B67D5/40

CPC classification number: B05B11/307 ,  A61F9/0008 ,  A61F9/0026 ,  A61M11/00 ,  A61M15/0066 ,  B05B1/3436 ,  B05B11/0032 ,  B05B11/0048 ,  B05B11/0075 ,  B05B11/3001 ,  B05B11/3004 ,  B05B11/3011 ,  B05B11/3015 ,  B05B11/3016 ,  B05B11/3059 ,  B05B11/3061 ,  B05B11/3074

Abstract: With the subject invention, a pump (100) is formed that generally includes a reservoir (128) formed to accommodate at least one fluid dose, and a fluid-collecting chamber (136) in fluid communication with a reservoir (128). The fluid-collecting chamber (136) includes a dose-control portion (138) which encompasses a volume defined by two dimensions. A first piston (106) is disposed to urge fluid from the reservoir (128) and at least into the dose-control portion (138). A second piston (154) is dispensed to reversibly slide within at least the dose-control portion (138) of the fluid-collecting chamber (136). A nozzle (160) is also provided which is located such that fluid displaced by the second piston (154) from the dose-control portion (138) is generally urged towards the nozzle (160). A check valve (254) may be placed in the fluid path between the dose-control portion (138) and the nozzle (160).

Abstract translation: 对于本发明，形成泵（100），其通常包括形成为容纳至少一种流体剂量的储存器（128）和与储存器（128）流体连通的流体收集室（136）。 流体收集室（136）包括包含由二维限定的体积的剂量控制部分（138）。 第一活塞（106）设置成将液体从储存器（128）推出并且至少进入剂量控制部分（138）。 分配第二活塞（154）以在至少液体收集室（136）的剂量控制部分（138）内可逆地滑动。 还设置有喷嘴（160），其被定位成使得通过第二活塞（154）从剂量控制部分（138）移位的流体通常被推向喷嘴（160）。 止回阀（254）可以放置在剂量控制部分（138）和喷嘴（160）之间的流体路径中。

公开(公告)号：WO2002068317A1

公开(公告)日：2002-09-06

申请号：PCT/US2002/005864

申请日：2002-02-21

Applicant: COHEN, Ben, Z. ,  KELLY, Nigel

Inventor： COHEN, Ben, Z. ,  KELLY, Nigel

IPC: B67D5/42

CPC classification number: G01F11/025 ,  A61F9/0008 ,  B05B11/0016 ,  B05B11/3011 ,  B05B11/3015 ,  B05B11/3056 ,  B05B11/3057 ,  B05B11/307 ,  B05B11/3074 ,  B05B11/3077 ,  F04B9/14

Abstract: With the subject invention, a pump (100) may be formed that generally includes a reservoir (112) formed to accommodate at least one fluid dose, and a fluid-collecting chamber (114) in communication with the reservoir. The fluid-collecting chamber is located such that fluid from the reservoir is fed thereinto, preferably gravitationally. A piston (126) is disposed to reversibly slide within at least a dose-control portion (118) of the fluid-collecting chamber, and the piston is configured such that upon sliding within the dose-control portion, the piston seals or substantially seals the dose-control portion from other portions of the fluid collecting chamber. The piston is configured to displace a volume of fluid from the sealed or substantially sealed dose-control portion which is approximately equal to or greater than the volume of one of the doses of the pump.

Abstract translation: 对于本发明，可以形成泵（100），其通常包括形成为容纳至少一种流体剂量的储存器（112）和与储存器连通的流体收集室（114）。 流体收集室被定位成使得来自储存器的流体被馈送到其中，优选地被引入重力。 活塞（126）设置成在流体收集室的至少一个剂量控制部分（118）内可逆地滑动，并且活塞构造成使得在剂量控制部分内滑动时，活塞密封或基本上密封 来自流体收集室的其它部分的剂量控制部分。 该活塞构造成使一定体积的流体从密封或基本上密封的剂量控制部分移位，其大约等于或大于泵的一个剂量的体积。

公开(公告)号：WO2008124841A3

公开(公告)日：2008-11-27

申请号：PCT/US2008059940

申请日：2008-04-10

Applicant: BARD INC C R ,  COHEN BEN ,  ROBLES DYLAN K ,  MESSERLY SHAYNE ,  BURNSIDE EDDIE K

Inventor： COHEN BEN ,  ROBLES DYLAN K ,  MESSERLY SHAYNE ,  BURNSIDE EDDIE K

IPC: G01S7/52 ,  G01S15/89

CPC classification number: A61B8/145 ,  A61B8/4472 ,  A61B8/4483 ,  A61B8/461 ,  A61B8/5207 ,  A61B8/56 ,  G01S7/003 ,  G01S7/52017 ,  G01S7/5208 ,  G01S7/52082 ,  G01S7/52085 ,  G01S7/52096 ,  G01S15/8909

Abstract: A low power ultrasound system for use in sonography applications, including vascular imaging, is disclosed. In one embodiment, the low power ultrasound system comprises a base unit that includes an image processor and a display. An ultrasound probe is operably connected to the base unit. The probe includes a head portion including an array of crystal transducers. A plurality of pulser/receiver modules that cause the transducers to emit ultrasonic transmit pulses are also included in the probe. The pulser/receiver modules are further configured to receive analog signals relating to ultrasonic echo receive pulses detected by the transducers. The probe includes a singular low noise amplifier that amplifies the analog signals, and an analog-to-digital converter that converts the analog signals to a digital signal. A wireless interface is included for enabling the digital signal to be wirelessly transmitted from the probe to the image processor of the base unit.

Abstract translation: 公开了用于超声波应用（包括血管成像）的低功率超声波系统。 在一个实施例中，低功率超声系统包括基座单元，该基座单元包括图像处理器和显示器。 超声探头可操作地连接到基座单元。 探针包括包含晶体换能器阵列的头部。 探头还包括使换能器发射超声波发射脉冲的多个脉冲发生器/接收器模块。 脉冲发生器/接收器模块进一步被配置为接收与由换能器检测到的超声回波接收脉冲有关的模拟信号。 该探头包括一个用于放大模拟信号的单个低噪声放大器，以及一个将模拟信号转换为数字信号的模数转换器。 包括一个无线接口，使数字信号能够从探头无线传输到基本单元的图像处理器。

公开(公告)号：WO2013130710A1

公开(公告)日：2013-09-06

申请号：PCT/US2013/028161

申请日：2013-02-28

Applicant: COHEN, Ben, Z.

Inventor： COHEN, Ben, Z. ,  SAFDIE, Daniel, Beitner

IPC: A61L2/10

CPC classification number: A61B90/30 ,  A61B46/00 ,  A61B46/10 ,  A61B50/10 ,  A61B50/13 ,  A61B50/15 ,  A61B50/33 ,  A61B90/36 ,  A61B90/90 ,  A61B90/92 ,  A61B2050/105 ,  A61B2050/155 ,  A61B2050/3015

Abstract: The subject invention provides a surgical instrument support assembly which includes an enclosure defining an opening; a light transmissive pane located at least partially across the opening and defining a support surface; and, a light source located inside the enclosure for generating light to be transmitted through the light transmissive pane. A sterilizable light transmissive surgical instrument support may be also provided to be disposed over at least a portion of the light transmissive pane. Advantageously, with, the subject invention, an assembly is provided which includes a sterilized surface for supporting surgical instruments which is backlit. With this arrangement, surgical instruments may be supported and illuminated from beneath to aid a medical practitioner in identifying the surgical instruments.

Abstract translation: 本发明提供了一种手术器械支撑组件，其包括限定开口的外壳; 至少部分地穿过所述开口并限定支撑表面的透光窗格; 以及位于外壳内的光源，用于产生要透过透光窗格的光。 还可以提供可消毒的透光手术器械支撑件以设置在透光窗格的至少一部分上。 有利地，在本发明中，提供了一种组件，其包括用于支撑背光的外科器械的消毒表面。 通过这种安排，手术器械可以从下方被支撑和照亮，以帮助医务人员识别手术器械。

公开(公告)号：WO2002062344A1

公开(公告)日：2002-08-15

申请号：PCT/US2002/003130

申请日：2002-02-04

Applicant: COHEN, Ben, Z. ,  KELLY, Nigel

Inventor： COHEN, Ben, Z. ,  KELLY, Nigel

IPC: A61K31/535

CPC classification number: A61K9/0048

Abstract: A method is provided of treating an eye with ophthalmologically active compounds, particularly with intra-ocular pressure lowering (IOP) compounds, where a dose of 5-15 microliters is delivered at a standard concentration.

Abstract translation: 提供了一种用眼科活性化合物治疗眼睛的方法，特别是眼压降低（IOP）化合物，其中以标准浓度递送5-15微升的剂量。