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    SYSTEM AND METHOD OF CONTROL OF A RECIPROCATING ELECTROKINETIC PUMP
    1.
    发明申请
    SYSTEM AND METHOD OF CONTROL OF A RECIPROCATING ELECTROKINETIC PUMP 审中-公开
    复合电动泵的控制系统及方法

    公开(公告)号：WO2015095590A1

    公开(公告)日：2015-06-25

    申请号：PCT/US2014/071270

    申请日：2014-12-18

    Applicant: EKSIGENT TECHNOLOGIES LLC

    Inventor： NIP, Kenneth, Kei-ho ,  LEWIS, Robert, B. ,  SHIEH, Doris, Sun-chia

    IPC: F04B49/06

    CPC classification number: F04B13/00 ,  F04B17/00 ,  F04B19/006 ,  F04B49/065

    Abstract: A method of controlling the output of an electrokinetic pump includes: (1) measuring an initial pressure in an electrokinetic pump system; (2) applying a pump drive signal to the electrokinetic pump to begin a pump stroke; (3) measuring the pressure after a predetermined time of applying the pump drive signal; (4) identifying when the pressure has returned to the initial pressure plus a constant; and (5) stopping the pump drive signal to complete the stroke.

    Abstract translation: 控制电动泵的输出的方法包括：（1）测量电动泵系统中的初始压力; （2）将泵驱动信号施加到电动泵以开始泵冲程; （3）在施加泵驱动信号的预定时间之后测量压力; （4）确定压力何时恢复到初始压力加常数; 和（5）停止泵驱动信号以完成行程。

    MICROFLUIDIC SYSTEMS, DEVICES AND METHODS FOR REDUCING NOISE GENERATED BY MECHANICAL INSTABILITIES
    3.
    发明申请
    MICROFLUIDIC SYSTEMS, DEVICES AND METHODS FOR REDUCING NOISE GENERATED BY MECHANICAL INSTABILITIES 审中-公开
    微流体系统，减少机械性不稳定产生噪音的装置和方法

    公开(公告)号：WO2007021755A3

    公开(公告)日：2007-10-11

    申请号：PCT/US2006031054

    申请日：2006-08-10

    Applicant: EKSIGENT TECHNOLOGIES LLC ,  CRENSHAW HUGH C ,  COLONELL JENNIFER ,  HARTMANN DANIEL M ,  NEVILL JOSHUA T ,  WYRICK DAVID W

    Inventor： CRENSHAW HUGH C ,  COLONELL JENNIFER ,  HARTMANN DANIEL M ,  NEVILL JOSHUA T ,  WYRICK DAVID W

    IPC: C12M3/00

    CPC classification number: B01F5/0646 ,  B01F5/0647 ,  B01F13/0059 ,  B01L3/5027 ,  Y10T137/0329 ,  Y10T137/86131 ,  Y10T137/87249

    Abstract: Microfluidic Systems, Devices and Methods for Reducing Noise Generated by Mechanical Instabilities. According to one embodiment, a microfluidic device is provided for reducing noise in a fluid mix. The microfluidic device can include microscale channels for passage of fluids to a mixing junction. The mixing channel can be adapted to combine the fluids into a common fluid flow. The microfluidic device can also include a connector channel including first and second ends. The first end of the connector channel can be connected to the mixing junction. The microfluidic device can also include an expansion channel having connection to the second end of the connector channel. The expansion channel can be adapted for passage of the fluid mix through the expansion channel to reduce concentration gradient noise of the fluid mix by dispersion of the fluid mix as the fluid mix passes through the expansion channel.

    Abstract translation: 微流控系统，降低机械不稳定噪声的设备和方法。 根据一个实施例，提供了用于减少流体混合物中的噪声的微流体装置。 微流体装置可以包括用于将流体通过混合结的微细通道。 混合通道可适于将流体组合成公共的流体流。 微流体装置还可以包括包括第一端和第二端的连接器通道。 连接器通道的第一端可以连接到混合连接点。 微流体装置还可以包括具有连接到连接器通道的第二端的扩张通道。 膨胀通道可适于使流体混合物通过膨胀通道，以在流体混合物通过膨胀通道时通过流体混合物的分散来减小流体混合物的浓度梯度噪声。

    FLOW RATE CONTROL
    5.
    发明申请
    FLOW RATE CONTROL 审中-公开

    公开(公告)号：WO2004112960A3

    公开(公告)日：2004-12-29

    申请号：PCT/US2004/015838

    申请日：2004-05-19

    Applicant: EKSIGENT TECHNOLOGIES LLC ,  NEYER, David, W. ,  RAKESTRAW, David, J. ,  REHM, Jason, E.

    Inventor： NEYER, David, W. ,  RAKESTRAW, David, J. ,  REHM, Jason, E.

    IPC: G01N1/00

    Abstract: A liquid sample is prepared at a preparation site and then processed, e.g. in an HPLC column. Fluid supplies (20A, 20B) supply working fluids at flow rates measured by flow meters (24A, 24B). Rotary valve (12) has six external ports (12A-12F). The outputs of the working fluids are combined and delivered to port (12A). Port (12B) is connected via loading conduit (181) to µLC column (18), the output of which flows to detector (26). A controller (22) controls the operation of valve (12) and supplies (20A, 20B), using input from the flow meters.

    FLOW RATE CONTROL
    6.
    发明申请
    FLOW RATE CONTROL 审中-公开
    流量控制

    公开(公告)号：WO2004112960A2

    公开(公告)日：2004-12-29

    申请号：PCT/US2004/015838

    申请日：2004-05-19

    Applicant: EKSIGENT TECHNOLOGIES LLC ,  NEYER, David, W. ,  RAKESTRAW, David, J. ,  REHM, Jason, E.

    Inventor： NEYER, David, W. ,  RAKESTRAW, David, J. ,  REHM, Jason, E.

    IPC: B01L

    CPC classification number: G01N30/16 ,  G01N2030/324 ,  Y10T436/2575

    Abstract: A liquid sample is prepared at a preparation site and then processed, e.g. in an HPLC column. The sample is prepared and conveyed to the device at a flow rate which is substantially less than the flow rate through the device. The different flow rates are preferably provided by variable rate working fluid supplies which drive the sample from the preparation site and through the device.

    Abstract translation: 在制备部位制备液体样品，然后加工，例如 在HPLC柱中。 制备样品并以基本上小于通过装置的流速的流速将其输送到装置。 不同的流速优选由可变速率的工作流体供应提供，驱动样品从制备部位并通过该装置。

    FLOW CONTROL SYSTEM
    8.
    发明申请
    FLOW CONTROL SYSTEM 审中-公开
    流量控制系统

    公开(公告)号：WO2004027535A1

    公开(公告)日：2004-04-01

    申请号：PCT/US2003/030008

    申请日：2003-09-17

    Applicant: EKSIGENT TECHNOLOGIES, LLC ,  PAUL, Phillip, H. ,  REHM, Jason, E. ,  ARNOLD, Don Wesley

    Inventor： PAUL, Phillip, H. ,  REHM, Jason, E. ,  ARNOLD, Don Wesley

    IPC: G05D7/06

    CPC classification number: G05D7/0682 ,  G01N30/32 ,  G01N30/34 ,  G01N2030/324 ,  G01N2030/326 ,  G05D7/0694 ,  G05D11/132 ,  G01N2030/285

    Abstract: Method and apparatus for providing liquid flow at a controlled rate less than 100 microliters/minute, and for varying the flow rate in a desired way. A liquid is driven through a conduit by pressure. The rate of flow of the liquid through the conduit is measured and compared to a desired value. The resulting information is then used to make any desirable changes in the driving pressure. In one embodiment, which is particularly suitable for a mixture of liquids to be supplied to a gradient liquid chromatography column, the rate of flow of each of two or more different liquids is controlled individually, and the liquids are then mixed together.

    Abstract translation: 以小于100微升/分钟的受控速率提供液体流量的方法和装置，以及以期望的方式改变流速。 液体通过压力被驱动通过导管。 测量液体通过导管的流速，并将其与期望值进行比较。 然后使用所得到的信息来进行驱动压力的任何期望的改变。 在一个特别适用于供应到梯度液相色谱柱的液体混合物的实施方案中，分别控制两种或多种不同液体中每种液体的流速，然后将液体混合在一起。

    MICROSCALE ELECTROCHEMICAL CELL AND METHODS INCORPORATING THE CELL
    10.
    发明申请
    MICROSCALE ELECTROCHEMICAL CELL AND METHODS INCORPORATING THE CELL 审中-公开
    MICROSCALE电化学细胞和包含细胞的方法

    公开(公告)号：WO2007087632A2

    公开(公告)日：2007-08-02

    申请号：PCT/US2007061148

    申请日：2007-01-26

    Applicant: EKSIGENT TECHNOLOGIES LLC ,  ARNOLD DON W ,  JIANG GUIFENG ,  HEBERT NICOLE E

    Inventor： ARNOLD DON W ,  JIANG GUIFENG ,  HEBERT NICOLE E

    IPC: G01N27/26

    CPC classification number: G01N27/403

    Abstract: An electrochemical cell 100 for processing a sample fluid, has a body 102 with a flow path 106, the flow path having an inlet 110 and an outlet 112; a reference electrode 122, 144 in fluid communication with the flow path; a counter electrode 124, 146 in fluid communication with the flow path; a porous working electrode 128 in fluid communication with the flow path, the working electrode having a working electrode material; an electrical connection 126 for the working electrode in electrical contact with the working electrode; and a working electrode section 132 in the flow path. The working electrode is positioned inside the working electrode section. The working electrode section has a volume of from about 1 pL to about 1 µL.

    Abstract translation: 用于处理样品流体的电化学电池100具有带流路106的主体102，流路具有入口110和出口112; 与流路连通的参考电极122,144; 与流路流体连通的对置电极124,146; 与流路流体连通的多孔工作电极128，工作电极具有工作电极材料; 用于与工作电极电接触的工作电极的电连接126; 和流路中的工作电极部132。 工作电极位于工作电极部分内。 工作电极部分具有约1pL至约1μL的体积。

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