摘要:
A fluidic pump on a monolithic chip. A closed length of channel is disposed on the chip, with a plurality of energizers disposed along the length of the channel. Each energizer is associated with a unique energizer designation. An first controller and energizer fire control lines are also disposed on the chip. One each of the energizer fire control lines is electrically connecting one each of the energizers to the first controller. Inputs are electrically connected to the first controller, for connecting the first controller to an second controller that is not disposed on the chip. The inputs include a power input, a ground input, and an enable input. The first controller has circuitry to (a) receive from the second controller an enable on the enable input, (b) send a timed sequence of fire commands on the energizer fire control lines to a selected number of energizers that is greater than one, starting with a stored starting energizer and ending with an ending energizer, and (c) update the stored starting energizer with the designation for the energizer next following the ending energizer.
摘要:
A microfluidic device with reduced risk of bubble formation at a capillary junction between two conduits is provided. In some embodiments, the microfluidic device comprises a supply reservoir, a first conduit and a second conduit. The first conduit is configured such that liquid flows by capillary effect from the supply reservoir into the first conduit. The second conduit is connected to the first conduit through an opening in a wall of the first conduit and is configured such that liquid flows from the first conduit to the second conduit by capillary effect. A width of the second conduit, along a direction of liquid flow in the first conduit, is greater than a depth of the second conduit and a depth of the second conduit is less than a depth of the first conduit.
摘要:
The microfluidic devices and systems disclosed herein reduce sample loss and help decrease sample processing bottlenecks for applications such as next generation sequencing (NGS). The microfluidic devices include a plurality of reaction modules. Each reaction module may comprise one or more reaction circuits. Each reaction circuit may comprise a single reaction flow channel with each reaction circuit connected by a bridge flow channel. Alternatively, each reaction circuit may comprise two or more reaction flow channels connected by two or more bridge flow channels. The combination of any two bridge flow channels and a portion of the two or more reaction flow channels between the any two bridge flow channels defining may define the reaction circuit. The reaction module may be arranged as nodes connected by bridge flow channels or each reaction module may be arranged in a parallel fashion on the microfluidic device.
摘要:
An apparatus and method, the apparatus comprising: a microfluidic channel (3); an electromechanical gel (5) provided within the microfluidic channel (3); at least one pair of electrodes (7) wherein the at least one pair of electrodes (7) are configured to control the electric field across the microfluidic channel (3) to cause the electromechanical gel (5) to deform in response to a voltage applied to the electrodes (7) such that the deformation enables fluid to be pumped through the microfluidic channel (3).
摘要:
A nanoscale probe includes a substrate and a pair of nanoscale wires each having a first end disposed on the substrate and a second end. The second ends of each nanoscale wire are in contact with one another such that the pair of nanoscale wires form a bridge extending over the substrate. The nanoscale wires may be electrically connected to electrodes residing on the substrate. The electrodes, in turn, are connected to an active electronic device such as a readout device or microprocessor formed in the substrate on which the probe is located. In this way a property of the nanoscale wires, and thus of the cell, may be determined.
摘要:
The invention relates to a pump comprising: a first substrate, at least one channel formed in a face of the first substrate, a second substrate (6) having a face mounted on the face of the first substrate, and an assembly (64) for measuring the temperature or the flow of a pumped fluid, said assembly comprising: inside one of the substrates (6), a compartment (66) entirely filled with a thermally insulating solid material (72) having an outer face (74) flush with the inside of the tube or the chamber; and a temperature probe (68, 69) arranged above the compartment, on the outer face of the insulating material, in order to thermally insulate said probe from the substrate.
摘要:
본 발명은 유체의 이동을 허용하는 멤브레인; 및 상기 멤브레인의 양측에 각각 마련되고, 유체의 이동을 허용하도록 다공성 재질 또는 구조로 이루어지고, 가역적인 전기화학 반응을 일으키기 위한 물질로 이루어지는 제 1 및 제 2 전극을 포함하고, 상기 제 1 및 제 2 전극에 전압을 교번하여 반대방향으로 공급함으로써 상기 전기화학 반응이 정방향과 역방향으로 반복해서 일어나도록 하여 상기 유체의 이동 방향 변화로 인해 펌핑력을 발생시키도록 하고, 상기 제 1 및 제 2 전극이 재생되도록 하는 가역적 전극반응을 이용한 전기삼투펌프 및 이를 이용한 유체 펌핑 시스템에 관한 것이다. 본 발명에 따르면, 전기삼투펌프를 크기 및 구성을 그대로 유지하면서 다량의 유체를 장시간 이동시킬 수 있도록 하고, 가역적 반응에 의해 전극의 재생이 가능하도록 하며, 가스의 발생이 없도록 하여 전기삼투펌프의 활용도를 높일 수 있다.
摘要:
A mechanical driver comprising a wedge shaped member operatively coupled to a shape memory alloy such that the shape memory alloy is able to displace the wedge shaped member in an essentially linear direction. The wedge shaped member is in constant contact with a lever arranged so that it can rotate about a fixed pivot point. A piston is arranged such that it is constant contact with the lever at a point between the pivot point of the lever and the contact point between the lever and the wedge shaped member. Return springs are provided to return the piston, lever and wedge shaped member to their respective start positions. Activation of the shape memory alloy displaces the wedge shaped member along its linear direction and this causes the lever to be deflected about its pivot point and the piston to be deflected in an essentially linear direction that is perpendicular to the linear direction of travel of the wedge shaped member.
摘要:
A fluid dispensing system comprising a pump (4) and a dispenser spray head comprising at least one nozzle through which fluid to be dispensed exits, the pump (4) comprising a stator (14) and a rotor (12) mounted in a chamber of the stator and rotatably displaceable with respect to the stator (14) around an axis of rotation (Ar) and axially along said axis (Ar), said axial displacement of the rotor in a first axial direction (A1) configured to effect a pump filling operation drawing in fluid via an inlet (8) into the stator chamber and in an opposite second axial direction (A2) configured to effect a dispensing operation expulsing the fluid in the chamber out of an outlet (10) of the pump. The outlet of the pump is positioned in the rotor and the dispenser spray head is fluidly connected to the outlet of the pump and is positioned at or adjacent an axial output end (19) of the rotor. The dispenser spray head is configured to dispense fluid at least partially in a radial direction (R) and encircling the axis of rotation.
摘要:
Ein Fluidausgabesystem, aufweisend eine Pumpe (4) und einen Ausgabesprühkopf, aufweisend mindestens eine Düse, durch die auszugebendes Fluid austritt, wobei die Pumpe (4) einen Stator (14) und einen Rotor (12) aufweist, der in einer Kammer des Stators angebracht und in Bezug auf den Stator (14) um eine Drehachse (Αή und axial entlang der Achse (Ar) drehbar ist, wobei die axiale Verschiebung des Rotors in eine erste axiale Richtung (A1) so konfiguriert ist, dass sie einen Pumpenfüllbetrieb bewirkt, in dem ein Fluid über einen Einlass (8) in die Statorkammer gezogen wird, und die axiale Verschiebung in eine entgegengesetzte zweite axiale Richtung (A2) so konfiguriert ist, dass sie einen Ausgabebetrieb bewirkt, in dem das Fluid in der Kammer aus einem Auslass (10) der Pumpe ausgetrieben wird. Der Auslass der Pumpe ist in dem Rotor angeordnet und der Ausgabesprühkopf ist mit dem Auslass der Pumpe in Fluidverbindung und an einem axialen oder angrenzend an ein axiales Auslassende (19) des Rotors angeordnet. Der Ausgabesprühkopf ist so konfiguriert, dass er Fluid zumindest teilweise in eine radiale Richtung (R) und die Drehachse umgebend ausgibt.