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    CORNEAL AND EPITHELIAL REMODELLING
    1.
    发明申请
    CORNEAL AND EPITHELIAL REMODELLING 审中-公开
    角膜和上皮重塑

    公开(公告)号：WO2008014544A1

    公开(公告)日：2008-02-07

    申请号：PCT/AU2007/001063

    申请日：2007-07-31

    Applicant: THE INSTITUTE FOR EYE RESEARCH ,  CHOO, Jennifer, Denise ,  HO, Arthur ,  MEYERS, William, E. ,  CONRAD, Fabian ,  HOLDEN, Brien, Anthony

    Inventor： CHOO, Jennifer, Denise ,  HO, Arthur ,  MEYERS, William, E. ,  CONRAD, Fabian ,  HOLDEN, Brien, Anthony

    IPC: G02C7/04 ,  A61B3/10 ,  A61F9/00

    CPC classification number: G02C7/047 ,  A61B3/107 ,  A61F9/007 ,  G02C2202/24

    Abstract: This invention relates to methods of shaping the anterior surface of the eye for controlling the progression of refractive error of the eye, in particular, myopia. The method employs the fitting of orthokeratology lenses having a precisely shaped posterior surface adapted to accurately shape the peripheral region of the eye. The method includes the steps of assessing central and peripheral refractive error parameters for the eye, determining the optimal anterior surface profile for the eye, including at both the optical centre of the cornea and at a selected optical periphery of the cornea, which would result in a desired refractive correction to achieve good vision for the eye and the desired peripheral refraction (curvature of field) for the eye for controlling progression of myopia. Accurate measurement of the shape of the pre-treated eye is important, thereby enabling a corresponding lens profile to be designed or selected so that the treatment process achieves a post-treatment peripheral profile which optimally focuses peripheral rays anteriorly of the retina, thereby controlling the progression of myopia. The invention extends to a lens manufactured so as to optimally treat the peripheral region of the eye.

    Abstract translation: 本发明涉及使眼睛的前表面成形以控制眼睛的屈光不正的进展，特别是近视的方法。 该方法采用具有精确成形后表面的角膜矫形镜片的装配，以适当地使眼睛周边区域成形。 该方法包括以下步骤：评估眼睛的中心和周边屈光不正参数，确定眼睛的最佳前表面轮廓，包括在角膜的光学中心和角膜的选定的光学周边，这将导致 期望的屈光矫正以实现眼睛的良好视力和用于眼睛控制近视进展的期望的周边折射（曲率））。 预处理眼睛的形状的准确测量是重要的，从而使得能够设计或选择相应的透镜轮廓，使得治疗过程实现后处理的外围轮廓，其最佳地聚焦视网膜前方的外周射线，从而控制 近视进展。 本发明延伸到制造以最佳地治疗眼睛周边区域的镜片。

    METHOD AND APPARATUS FOR CONTROLLING PERIPHERAL IMAGE POSITION FOR REDUCING PROGRESSION OF MYOPIA
    3.
    发明申请
    METHOD AND APPARATUS FOR CONTROLLING PERIPHERAL IMAGE POSITION FOR REDUCING PROGRESSION OF MYOPIA 审中-公开
    用于控制外周图像位置以减少MYOPIA进展的方法和装置

    公开(公告)号：WO2007082268A2

    公开(公告)日：2007-07-19

    申请号：PCT/US2007060395

    申请日：2007-01-11

    Applicant: INST EYE RES ,  HO ARTHUR ,  SMITH EARL LEO III ,  SANKARIDURG PADMAJA ,  HOLDEN BRIEN ANTHONY

    Inventor： HO ARTHUR ,  SMITH EARL LEO III ,  SANKARIDURG PADMAJA ,  HOLDEN BRIEN ANTHONY

    CPC classification number: G02C7/02 ,  A61F9/008 ,  A61F2009/00872 ,  G02C7/047 ,  G02C2202/24

    Abstract: A method and apparatus are disclosed for controlling optical aberrations to alter relative curvature of field by providing optical devices and methods comprising the repositioning of peripheral off-axis focal points relative to the retina to produce stimulus for influencing the progression of refractive error while simultaneously controlling the position of the central focal point near to the retina to provide clear central vision and simultaneously providing zones of controlled peripheral defocus and other optical aberrations to improve peripheral vision for select directions of gaze.

    Abstract translation: 公开了一种通过提供光学装置和方法来控制光学像差以改变相对曲率的方法和装置，所述光学装置和方法包括相对于视网膜重新定位外围离轴焦点，以产生用于影响屈光不正的进展的刺激，同时控制 中心焦点靠近视网膜的位置，以提供清晰的中央视觉，同时提供受控外围散焦和其他光学像差的区域，以改善注视方向的周边视力。

    MEANS FOR CONTROLLING THE PROGRESSION OF MYOPIA
    4.
    发明申请
    MEANS FOR CONTROLLING THE PROGRESSION OF MYOPIA 审中-公开
    控制MYOPIA进展的手段

    公开(公告)号：WO2007146673A3

    公开(公告)日：2008-02-28

    申请号：PCT/US2007070419

    申请日：2007-06-05

    Applicant: VISION CRC LTD ,  HOLDEN BRIEN ANTHONY ,  HO ARTHUR ,  SANKARIDURG PADMAJA RAJAGOPAL ,  ALLER THOMAS ARTHUR ,  SMITH EARL LEO III

    Inventor： HOLDEN BRIEN ANTHONY ,  HO ARTHUR ,  SANKARIDURG PADMAJA RAJAGOPAL ,  ALLER THOMAS ARTHUR ,  SMITH EARL LEO III

    IPC: G02C7/04

    CPC classification number: G02C7/044 ,  G02C7/04 ,  G02C7/042 ,  G02C7/061 ,  G02C2202/24

    Abstract: A contact lens (10) for use in controlling or retarding the progression of myopia in an eye has a central optical zone (20) approximating the normal diameter of the pupil of the eye (22) that gives clear central vision at distance for the wearer. An annular peripheral optical zone 24 that is substantially outside the diameter of the pupil is formed around the central optical zone (20) with greater refractive power than that of the central zone (22) so that oblique rays entering the eye through the peripheral optical zone (24) will be brought to focus at a focal plane that is substantially on or anterior to the peripheral region of the retina. Preferably, the rear surface (16) of the lens is shaped to conform to the cornea of the eye and the front surface (18) of the lens (10) is shaped to provide - in conjunction with the rear surface (16) - the desired optical properties of the central and peripheral optical zones. The front surface (18) is also preferably contoured to form a smooth transition (30) between the junction of the central optical zone (20) and the peripheral optical zone (24), with or without designed optical properties such as progressive power.

    Abstract translation: 用于控制或延缓眼睛近视进展的隐形眼镜（10）具有近似于眼睛（22）的瞳孔的正常直径的中心光学区域（20），其为佩戴者提供远距离的清晰的中心视觉 。 基本上位于瞳孔直径外侧的环形周边光学区域24围绕中心光学区域（20）以比中心区域（22）更大的折光力形成，使得通过外围光学区域进入眼睛的斜射线 （24）将被聚焦在基本上在视网膜周边区域的前方或前方的焦平面上。 优选地，透镜的后表面（16）成形为符合眼睛的角膜，并且透镜（10）的前表面（18）成形为与后表面（16）一起提供 - 中心和周边光学区域的所需光学特性。 前表面（18）还优选成形为在中心光学区（20）和周边光学区（24）的接合处之间形成平滑过渡（30），具有或不具有设计的光学特性（例如渐进屈光力）。

    MEANS FOR CONTROLLING THE PROGRESSION OF MYOPIA
    5.
    发明申请
    MEANS FOR CONTROLLING THE PROGRESSION OF MYOPIA 审中-公开
    控制MYOPIA进展的手段

    公开(公告)号：WO2007146673A2

    公开(公告)日：2007-12-21

    申请号：PCT/US2007/070419

    申请日：2007-06-05

    Applicant: VISION CRC LIMITED ,  HOLDEN, Brien, Anthony ,  HO, Arthur ,  SANKARIDURG, Padmaja, Rajagopal ,  ALLER, Thomas, Arthur ,  SMITH, Earl, Leo, Iii

    Inventor： HOLDEN, Brien, Anthony ,  HO, Arthur ,  SANKARIDURG, Padmaja, Rajagopal ,  ALLER, Thomas, Arthur ,  SMITH, Earl, Leo, Iii

    CPC classification number: G02C7/044 ,  G02C7/04 ,  G02C7/042 ,  G02C7/061 ,  G02C2202/24

    Abstract: A contact lens (10) for use in controlling or retarding the progression of myopia in an eye has a central optical zone (20) approximating the normal diameter of the pupil of the eye (22) that gives clear central vision at distance for the wearer. An annular peripheral optical zone 24 that is substantially outside the diameter of the pupil is formed around the central optical zone (20) with greater refractive power than that of the central zone (22) so that oblique rays entering the eye through the peripheral optical zone (24) will be brought to focus at a focal plane that is substantially on or anterior to the peripheral region of the retina. Preferably, the rear surface (16) of the lens is shaped to conform to the cornea of the eye and the front surface (18) of the lens (10) is shaped to provide - in conjunction with the rear surface (16) - the desired optical properties of the central and peripheral optical zones. The front surface (18) is also preferably contoured to form a smooth transition (30) between the junction of the central optical zone (20) and the peripheral optical zone (24), with or without designed optical properties such as progressive power.

    Abstract translation: 用于控制或延缓眼睛近视进展的隐形眼镜（10）具有近似于眼睛（22）的瞳孔的正常直径的中心光学区域（20），其为佩戴者提供远距离的清晰的中心视觉 。 基本上位于瞳孔直径外侧的环形周边光学区域24围绕中心光学区域（20）以比中心区域（22）更大的折光力形成，使得通过外围光学区域进入眼睛的斜射线 （24）将被聚焦在基本上在视网膜周边区域的前方或前方的焦平面上。 优选地，透镜的后表面（16）成形为符合眼睛的角膜，并且透镜（10）的前表面（18）成形为与后表面（16）一起提供 - 中心和周边光学区域的所需光学特性。 前表面（18）还优选成形为在中心光学区（20）和周边光学区（24）的接合处之间形成平滑过渡（30），具有或不具有设计的光学特性（例如渐进屈光力）。

    EYE TREATMENT
    10.
    发明申请
    EYE TREATMENT 审中-公开
    眼睛治疗

    公开(公告)号：WO2007128055A1

    公开(公告)日：2007-11-15

    申请号：PCT/AU2007/000586

    申请日：2007-05-03

    Applicant: VISION CRC LIMITED ,  HO, Arthur ,  HOLDEN, Brien Anthony ,  MANNS, Fabrice ,  PAREL, Jean-Marie Arthur

    Inventor： HO, Arthur ,  HOLDEN, Brien Anthony ,  MANNS, Fabrice ,  PAREL, Jean-Marie Arthur

    IPC: A61F9/013

    CPC classification number: A61F2/16 ,  A61F2/1624 ,  A61F2240/002 ,  A61L27/18 ,  A61L27/50 ,  A61L2430/16 ,  C08L83/04

    Abstract: The present invention relates to a method of determining the IOL refractive index for an ocular replacement material for replacing tissue in the capsular bag comprising combining a neutral (non-correcting) reference refractive index ("NRRI") of between 1.421 and 1.450 with a refractive index correction factor ("RICF") ascertained by reference to the refractive power required to correct the patient's refractive error. The present invention also relates to methods of treating presbyopia, myopia and hyperopia using the above method.

    Abstract translation: 本发明涉及一种确定用于更换囊袋中的组织的眼睛替代材料的IOL折射率的方法，包括将1.421和1.450之间的中性（非校正）参考折射率（“NRRI”）与折射率 通过参考校正患者的屈光不正所需的屈光力确定的指数校正因子（“RICF”）。 本发明还涉及使用上述方法治疗老花眼，近视和远视的方法。

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