公开(公告)号：WO2012014190A2

公开(公告)日：2012-02-02

申请号：PCT/IL2011/000452

申请日：2011-06-09

Applicant: NEW YORK UNIVERSITY ,  PASS, Harvey ,  HOSHEN, Moshe ,  GOREN, Yaron

Inventor： PASS, Harvey ,  HOSHEN, Moshe ,  GOREN, Yaron

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/158 ,  C12Q2600/178

Abstract: Described herein are compositions and methods for the prognosis of mesothelioma patients after surgical operation. Specifically the invention relates to microRNA molecules associated with prognosis of mesothelioma, as well as various nucleic acid molecules relating thereto or derived therefrom.

Abstract translation: 本文描述了外科手术后间皮瘤患者预后的组合物和方法。 具体地说，本发明涉及与间皮瘤预后相关的微小RNA分子以及与之相关的或从其衍生的各种核酸分子。

公开(公告)号：WO2010018563A3

公开(公告)日：2010-04-15

申请号：PCT/IL2009000764

申请日：2009-08-05

Applicant: ROSETTA GENOMICS LTD ,  MOR RESEARCH APPLIC LTD ,  HOSHEN MOSHE ,  LITHWICK YANAI GILA ,  LAHAV MEIR ,  AHARONOV RANIT

Inventor： HOSHEN MOSHE ,  LITHWICK YANAI GILA ,  LAHAV MEIR ,  AHARONOV RANIT

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12Q2600/178

Abstract: Described herein are compositions and methods for prognosis of malignant lymphoma. The compositions are microRNA molecules associated with the prognosis of lymphoma, as well as various nucleic acid molecules relating thereto or derived thereof.

Abstract translation: 本文描述了恶性淋巴瘤预后的组合物和方法。 组合物是与淋巴瘤的预后相关的微小RNA分子，以及与其相关或衍生的各种核酸分子。

公开(公告)号：WO2011039757A3

公开(公告)日：2011-12-29

申请号：PCT/IL2010000806

申请日：2010-10-04

Applicant: ROSETTA GENOMICS LTD ,  TEL HASHOMER MEDICAL INFRASTRUCTURE AND SERVICES LTD ,  HOSHEN MOSHE ,  DOTAN ZOHAR

Inventor： HOSHEN MOSHE ,  DOTAN ZOHAR

IPC: C12Q1/68 ,  C12P19/34

CPC classification number: C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/158 ,  C12Q2600/178

Abstract: Described herein are compositions and methods for the prognosis of renal cancer patients after surgical operation. Specifically the invention relates to microRNA molecules associated with the prognosis of renal cancer, as well as various nucleic acid molecules relating thereto or derived therefrom.

Abstract translation: 本文描述了用于外科手术后肾癌患者预后的组合物和方法。 具体而言，本发明涉及与肾癌预后相关的微RNA分子，以及与之相关或由其衍生的各种核酸分子。

公开(公告)号：WO2010018585A2

公开(公告)日：2010-02-18

申请号：PCT/IL2009/000803

申请日：2009-08-13

Applicant: NEW YORK UNIVERSITY ,  HERNANDO-MONGE, Eva ,  BELITSKAYA-LEVY, Ilana ,  HOSHEN, Moshe

Inventor： HERNANDO-MONGE, Eva ,  BELITSKAYA-LEVY, Ilana ,  HOSHEN, Moshe

IPC: C12Q1/68

CPC classification number: C12Q1/6809 ,  C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/136 ,  C12Q2600/178

Abstract: Described herein are compositions and methods for the prognosis of melanoma patients after surgical operation. Specifically the invention relates to microRNA molecules associated with the prognosis of melanoma, as well as various nucleic acid molecules relating thereto or derived therefrom.

Abstract translation: 本文描述了外科手术后黑色素瘤患者预后的组合物和方法。 具体地说，本发明涉及与黑素瘤的预后相关的微小RNA分子以及与之相关的或从其衍生的各种核酸分子。

公开(公告)号：WO2009147658A3

公开(公告)日：2010-01-28

申请号：PCT/IL2009000524

申请日：2009-05-26

Applicant: UNIV NEW YORK ,  PASS HARVEY ,  BENJAMIN HILA ,  HOSHEN MOSHE ,  IVANOV SERGEY

Inventor： PASS HARVEY ,  BENJAMIN HILA ,  HOSHEN MOSHE ,  IVANOV SERGEY

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/178 ,  Y10T436/143333

Abstract: Described herein are compositions and methods for the diagnosis and treatment of mesothelioma patients and the prognosis of mesothelioma patients after surgical operation. Specifically the invention relates to microRNA molecules associated with diagnosis, treatment and prognosis of mesothelioma, as well as various nucleic acid molecules relating thereto or derived therefrom.

Abstract translation: 本文描述了用于诊断和治疗间皮瘤患者的组合物和方法以及手术后间皮瘤患者的预后。 具体地说，本发明涉及与间皮瘤的诊断，治疗和预后相关的微小RNA分子以及与之有关的或与之相关的各种核酸分子。

公开(公告)号：WO2011130426A2

公开(公告)日：2011-10-20

申请号：PCT/US2011032347

申请日：2011-04-13

Applicant: UNIV NEW YORK ,  HERNANDO EVA ,  HOSHEN MOSHE ,  OSMAN IMAN ,  GAZIEL-SOVRAN AVITAL ,  SEGURA MIGUEL F

Inventor： HERNANDO EVA ,  HOSHEN MOSHE ,  OSMAN IMAN ,  GAZIEL-SOVRAN AVITAL ,  SEGURA MIGUEL F

IPC: A61K48/00

CPC classification number: A61K31/7088 ,  A61K45/06 ,  C12N15/1135 ,  C12N15/1137 ,  C12N2310/141 ,  C12N2330/51 ,  C12Y204/01041

Abstract: Described herein are compositions and methods for the prognosis, prevention and treatment of melanoma or melanoma associated symptoms. The compositions are microRNA molecules associated with melanoma or with melanoma brain tropism, as well as various nucleic acid molecules relating thereto or derived therefrom.

Abstract translation: 本文描述了预后，预防和治疗黑素瘤或黑素瘤相关症状的组合物和方法。 组合物是与黑素瘤或黑色素瘤脑向性相关的微小RNA分子，以及与之相关的或从其衍生的各种核酸分子。

公开(公告)号：WO2011039757A2

公开(公告)日：2011-04-07

申请号：PCT/IL2010/000806

申请日：2010-10-04

Applicant: ROSETTA GENOMICS LTD. ,  TEL HASHOMER MEDICAL INFRASTRUCTURE AND SERVICES LTD. ,  HOSHEN, Moshe ,  DOTAN, Zohar

Inventor： HOSHEN, Moshe ,  DOTAN, Zohar

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/158 ,  C12Q2600/178

Abstract: Described herein are compositions and methods for the prognosis of renal cancer patients after surgical operation. Specifically the invention relates to microRNA molecules associated with the prognosis of renal cancer, as well as various nucleic acid molecules relating thereto or derived therefrom.

Abstract translation: 本文描述了外科手术后肾癌患者预后的组合物和方法。 具体地说，本发明涉及与肾癌预后相关的微小RNA分子，以及与之相关的或从其衍生的各种核酸分子。

公开(公告)号：WO2010018585A3

公开(公告)日：2010-04-22

申请号：PCT/IL2009000803

申请日：2009-08-13

Applicant: UNIV NEW YORK ,  HERNANDO-MONGE EVA ,  BELITSKAYA-LEVY ILANA ,  HOSHEN MOSHE

Inventor： HERNANDO-MONGE EVA ,  BELITSKAYA-LEVY ILANA ,  HOSHEN MOSHE

IPC: C12Q1/68

CPC classification number: C12Q1/6809 ,  C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/136 ,  C12Q2600/178

Abstract: Described herein are compositions and methods for the prognosis of melanoma patients after surgical operation. Specifically the invention relates to microRNA molecules associated with the prognosis of melanoma, as well as various nucleic acid molecules relating thereto or derived therefrom.

Abstract translation: 本文描述了用于外科手术后黑素瘤患者预后的组合物和方法。 具体而言，本发明涉及与黑素瘤预后相关的微RNA分子以及与其相关或由其衍生的各种核酸分子。

公开(公告)号：WO2011130426A3

公开(公告)日：2011-10-20

申请号：PCT/US2011/032347

申请日：2011-04-13

Applicant: NEW YORK UNIVERSITY ,  HERNANDO, Eva ,  HOSHEN, Moshe ,  OSMAN, Iman ,  GAZIEL-SOVRAN, Avital ,  SEGURA, MIguel, F.

Inventor： HERNANDO, Eva ,  HOSHEN, Moshe ,  OSMAN, Iman ,  GAZIEL-SOVRAN, Avital ,  SEGURA, MIguel, F.

IPC: C12N15/11 ,  C12Q1/68 ,  C07H21/04

Abstract: Described herein are compositions and methods for the prognosis, prevention and treatment of melanoma or melanoma associated symptoms. The compositions are microRNA molecules associated with melanoma or with melanoma brain tropism, as well as various nucleic acid molecules relating thereto or derived therefrom.

公开(公告)号：WO2010018563A2

公开(公告)日：2010-02-18

申请号：PCT/IL2009/000764

申请日：2009-08-05

Applicant: ROSETTA GENOMICS LTD. ,  MOR RESEARCH APPLICATIONS LTD. ,  HOSHEN, Moshe ,  LITHWICK YANAI, Gila ,  LAHAV, Meir ,  AHARONOV, Ranit

Inventor： HOSHEN, Moshe ,  LITHWICK YANAI, Gila ,  LAHAV, Meir ,  AHARONOV, Ranit

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12Q2600/178

Abstract: Described herein are compositions and methods for prognosis of malignant lymphoma. The compositions are microRNA molecules associated with the prognosis of lymphoma, as well as various nucleic acid molecules relating thereto or derived thereof.

Abstract translation: 本文描述了用于预后恶性淋巴瘤的组合物和方法。 该组合物是与淋巴瘤的预后相关的微RNA分子，以及与之相关或由其衍生的各种核酸分子。