公开(公告)号：WO2013040473A1

公开(公告)日：2013-03-21

申请号：PCT/US2012/055599

申请日：2012-09-14

Applicant: COLD PLASMA MEDICAL TECHNOLOGIES, INC. ,  WATSON, Gregory, A. ,  HUMMEL, Robert, M. ,  JACOFSKY, Marc, C. ,  JACOFSKY, David, J.

Inventor： WATSON, Gregory, A. ,  HUMMEL, Robert, M. ,  JACOFSKY, Marc, C. ,  JACOFSKY, David, J.

IPC: H01J7/24

CPC classification number: H05H1/46 ,  A61L2/00 ,  A61L2/0011 ,  A61L2/0094 ,  A61L2/14 ,  A61L2202/11 ,  A61M15/02 ,  A61M16/06 ,  A61M16/12 ,  A61M2202/0208 ,  A61M2202/025 ,  A61N1/40 ,  A61N1/44 ,  H01J37/321 ,  H01J37/32348 ,  H01J37/3244 ,  H01J37/3266 ,  H05H1/2406 ,  H05H2001/2412 ,  H05H2001/466 ,  H05H2001/4682 ,  H05H2240/20 ,  H05H2245/1225 ,  H05H2277/10

Abstract: A cold plasma mask application device for delivery of a cold plasma to the face of a patient. An appropriate gas is introduced into a gas containment area that is energized by one or more electrodes that receive energy from a pulsed source. The plasma can be prevented from contact with the patient's face, or can be allowed to make contact with the patient's face at the appropriate treatment area. A three-layer approach to the manufacture of the cold plasma mask application device is also described. Such a device and method can be used to treat acne as well as complex facial wounds such as those resulting from trauma, melanoma, and other cancers of the face, rosacea, and psoriasis.

Abstract translation: 一种用于将冷血浆递送到患者面部的冷等离子体掩模施加装置。 将合适的气体引入到由一个或多个从脉冲源接收能量的电极激励的气体容纳区域中。 可以防止等离子体与患者的面部接触，或者允许在适当的治疗区域与患者的面部接触。 还描述了制造冷等离子体掩模施加装置的三层方法。 这种装置和方法可以用于治疗痤疮以及复杂的面部伤口，例如由创伤，黑素瘤和面部，酒渣鼻和牛皮癣的其它癌症引起的面部创伤。

公开(公告)号：WO2013016132A3

公开(公告)日：2013-07-25

申请号：PCT/US2012047387

申请日：2012-07-19

Applicant: TCI3 PRESSURE APPLIC LLC ,  JACOFSKY MARC C ,  JACOFSKY DAVID J

Inventor： JACOFSKY MARC C ,  JACOFSKY DAVID J

IPC: A47C27/08 ,  A47B7/02 ,  A47C27/10 ,  G01G19/52

CPC classification number: A47C31/123 ,  A47C27/083 ,  A61B5/0022 ,  A61B5/0024 ,  A61B5/447 ,  A61B5/6832 ,  A61B5/7275 ,  A61B2562/0247 ,  A61B2562/028 ,  A61G7/05776 ,  A61G2203/34 ,  A61G2203/46 ,  A61G2205/60 ,  F04C2270/041 ,  G06F19/3406 ,  G16H40/63

Abstract: A method for monitoring pressure at one or more points on an individual, and automatically adjusting one or more sections of a support structure. The method includes periodically receiving pressure data from one or more radio frequency addressable sensors placed on an individual; determining, based on the received pressure data, whether an adjustment in the support structure is required; systematically adjusting cells located within the plurality of zones, one zone at a time, until an improvement in pressure data is indicated, if an improvement in pressure data is indicated for a zone, systematically adjusting cells within the plurality of subzones for that zone, one subzone at a time, until an improvement in pressure data is indicated. if an improvement in pressure data is indicated for a subzone, systematically adjusting cells in that subzone, one cell at a time, until an improvement in pressure data is indicated.

Abstract translation: 一种用于监测个体上一个或多个点处的压力并自动调节支撑结构的一个或多个部分的方法。 该方法包括周期性地从放置在个体上的一个或多个射频可寻址传感器接收压力数据; 基于接收到的压力数据确定是否需要支撑结构中的调节; 系统地调整位于多个区域内的单元，一次一个区域，直到指示压力数据的改善，如果对区域指示了压力数据的改善，系统地调整该区域的多个子区域内的单元， 分区，直到显示压力数据的改进。 如果对分区指示压力数据的改善，则系统地调整该分区中的细胞，一次一个细胞，直到指示压力数据的改善。

公开(公告)号：WO2013040481A1

公开(公告)日：2013-03-21

申请号：PCT/US2012/055607

申请日：2012-09-14

Applicant: COLD PLASMA MEDICAL TECHNOLOGIES, INC. ,  WATSON, Gregory, A. ,  JACOFSKY, Marc, C. ,  JACOFSKY, David, J.

Inventor： WATSON, Gregory, A. ,  JACOFSKY, Marc, C. ,  JACOFSKY, David, J.

IPC: H05H1/24

CPC classification number: H05H1/46 ,  A61L2/00 ,  A61L2/0011 ,  A61L2/0094 ,  A61L2/14 ,  A61L2202/11 ,  A61M15/02 ,  A61M16/06 ,  A61M16/12 ,  A61M2202/0208 ,  A61M2202/025 ,  A61N1/40 ,  A61N1/44 ,  H01J37/321 ,  H01J37/32348 ,  H01J37/3244 ,  H01J37/3266 ,  H05H1/2406 ,  H05H2001/2412 ,  H05H2001/466 ,  H05H2001/4682 ,  H05H2240/20 ,  H05H2245/1225 ,  H05H2277/10

Abstract: A cold plasma sterilization device for sterilization of objects such as medical instruments. Gas is fed to a plasma chamber where it is energized by one or more electrodes coupled to a pulse source to thereby generate a cold plasma inside the plasma chamber. A dielectric barrier is sandwiched between the gas compartment and the electrodes to form a dielectric barrier discharge device, inside the plasma chamber, one or more conductive stands that are coupled to ground hold the object to-be-sterilized. The cold plasma exits the plasma chamber, where it is recirculated for further use as a plasma source in subsequent cycles. Gases that can be used include noble gases such as helium, or combinations of noble gases.

Abstract translation: 用于灭菌医疗器械等物体的冷等离子体灭菌装置。 气体被供给到等离子体室，其中一个或多个电极被耦合到脉冲源，从而在等离子体室内产生冷等离子体。 电介质阻挡层被夹在气室和电极之间以形成电介质阻挡放电装置，在等离子体室内部，一个或多个连接到地面的导电支架保持要被灭菌的物体。 冷等离子体离开等离子体室，在其中再循环，以便在随后的循环中进一步用作等离子体源。 可以使用的气体包括惰性气体如氦气或惰性气体的组合。

公开(公告)号：WO2013040476A1

公开(公告)日：2013-03-21

申请号：PCT/US2012/055602

申请日：2012-09-14

Applicant: COLD PLASMA MEDICAL TECHNOLOGIES, INC. ,  WATSON, Gregory A. ,  JACOFSKY, Marc C.

Inventor： WATSON, Gregory A. ,  JACOFSKY, Marc C.

IPC: H01J7/24

CPC classification number: H05H1/46 ,  A61L2/00 ,  A61L2/0011 ,  A61L2/0094 ,  A61L2/14 ,  A61L2202/11 ,  A61M15/02 ,  A61M16/06 ,  A61M16/12 ,  A61M2202/0208 ,  A61M2202/025 ,  A61N1/40 ,  A61N1/44 ,  H01J37/321 ,  H01J37/32348 ,  H01J37/3244 ,  H01J37/3266 ,  H05H1/2406 ,  H05H2001/2412 ,  H05H2001/466 ,  H05H2001/4682 ,  H05H2240/20 ,  H05H2245/1225 ,  H05H2277/10

Abstract: A cold plasma treatment device for delivery of a cold plasma to patient treatment area. Gas is fed to a gas compartment where it is energized by an electrode coupled to a pulse source to thereby generate a cold plasma. A dielectric barrier is sandwiched between the gas compartment and the electrode to form a dielectric barrier discharge device. The cold plasma exits the gas compartment via a bottom member having a plurality of holes. Gases that can be used include noble gases such as helium or combinations of noble gases.

Abstract translation: 用于将冷血浆输送到患者治疗区域的冷等离子体治疗装置。 气体被供给到气室，在那里通过耦合到脉冲源的电极通电，从而产生冷等离子体。 电介质阻挡层夹在气室和电极之间以形成电介质阻挡放电装置。 冷等离子体通过具有多个孔的底部构件离开气室。 可以使用的气体包括惰性气体如氦气或惰性气体的组合。

公开(公告)号：WO2013052261A3

公开(公告)日：2013-06-27

申请号：PCT/US2012055571

申请日：2012-09-14

Applicant: COLD PLASMA MEDICAL TECHNOLOGIES INC ,  WATSON GREGORY A ,  HUMMEL ROBERT M ,  JACOFSKY MARC C ,  JACOFSKY DAVID J

Inventor： WATSON GREGORY A ,  HUMMEL ROBERT M ,  JACOFSKY MARC C ,  JACOFSKY DAVID J

IPC: H01J7/24

CPC classification number: H05H1/46 ,  A61L2/00 ,  A61L2/0011 ,  A61L2/0094 ,  A61L2/14 ,  A61L2202/11 ,  A61M15/02 ,  A61M16/06 ,  A61M16/12 ,  A61M2202/0208 ,  A61M2202/025 ,  A61N1/40 ,  A61N1/44 ,  H01J37/321 ,  H01J37/32348 ,  H01J37/3244 ,  H01J37/3266 ,  H05H1/2406 ,  H05H2001/2412 ,  H05H2001/466 ,  H05H2001/4682 ,  H05H2240/20 ,  H05H2245/1225 ,  H05H2277/10

Abstract: A gas cartridge is described that is configured to provide sufficient gas to support cold plasma generation for a specific medical process. The gas cartridge has a seal that is pierced upon connection of the gas cartridge to the cold plasma delivery system. Different embodiments are described that use different connection locations between the gas cartridge and the cold plasma delivery system. A shroud is also described that shields the user if the cold plasma delivery system is dropped and the gas cartridge ruptures. Use of an ID system assists in ensuring that the correct gas mixture, correct gas cartridge and correct power supply settings are used for the particular medical treatment process.

Abstract translation: 描述了配置成提供足够的气体以支持特定医疗过程的冷等离子体产生的储气瓶。 储气筒具有密封件，在将储气筒连接到冷等离子体输送系统时，密封件被刺穿。 描述了使用储气瓶与冷等离子体输送系统之间的不同连接位置的不同实施例。 还描述了一种护罩，如果冷等离子体输送系统掉落并且储气筒破裂，则该护罩可以保护使用者。 使用ID系统有助于确保在特定的医疗处理过程中使用正确的气体混合物，正确的气体墨盒和正确的电源设置。

公开(公告)号：WO2013052261A2

公开(公告)日：2013-04-11

申请号：PCT/US2012/055571

申请日：2012-09-14

Applicant: COLD PLASMA MEDICAL TECHNOLOGIES, INC. ,  WATSON, Gregory, A. ,  HUMMEL, Robert, M. ,  JACOFSKY, Marc, C. ,  JACOFSKY, David, J.

Inventor： WATSON, Gregory, A. ,  HUMMEL, Robert, M. ,  JACOFSKY, Marc, C. ,  JACOFSKY, David, J.

IPC: A61M37/00

CPC classification number: H05H1/46 ,  A61L2/00 ,  A61L2/0011 ,  A61L2/0094 ,  A61L2/14 ,  A61L2202/11 ,  A61M15/02 ,  A61M16/06 ,  A61M16/12 ,  A61M2202/0208 ,  A61M2202/025 ,  A61N1/40 ,  A61N1/44 ,  H01J37/321 ,  H01J37/32348 ,  H01J37/3244 ,  H01J37/3266 ,  H05H1/2406 ,  H05H2001/2412 ,  H05H2001/466 ,  H05H2001/4682 ,  H05H2240/20 ,  H05H2245/1225 ,  H05H2277/10

Abstract: A gas cartridge is described that is configured to provide sufficient gas to support cold plasma generation for a specific medical process. The gas cartridge has a seal that is pierced upon connection of the gas cartridge to the cold plasma delivery system. Different embodiments are described that use different connection locations between the gas cartridge and the cold plasma delivery system. A shroud is also described that shields the user if the cold plasma delivery system is dropped and the gas cartridge ruptures. Use of an ID system assists in ensuring that the correct gas mixture, correct gas cartridge and correct power supply settings are used for the particular medical treatment process.

Abstract translation: 描述了一种气体盒，其构造成提供足够的气体以支持用于特定医疗过程的冷等离子体产生。 燃气筒具有密封件，该密封件在气瓶连接到冷等离子体输送系统时被刺穿。 描述了使用气瓶和冷等离子体输送系统之间的不同连接位置的不同实施例。 还描述了如果冷等离子体输送系统掉落并且气瓶破裂，则屏蔽用户。 使用ID系统有助于确保在特定医疗过程中使用正确的气体混合物，正确的气瓶和正确的电源设置。

公开(公告)号：WO2013040486A1

公开(公告)日：2013-03-21

申请号：PCT/US2012/055615

申请日：2012-09-14

Applicant: COLD PLASMA MEDICAL TECHNOLOGIES, INC. ,  WATSON, Gregory, A. ,  JACOFSKY, Marc, C.

Inventor： WATSON, Gregory, A. ,  JACOFSKY, Marc, C.

IPC: H01J7/24

CPC classification number: H05H1/46 ,  A61L2/00 ,  A61L2/0011 ,  A61L2/0094 ,  A61L2/14 ,  A61L2202/11 ,  A61M15/02 ,  A61M16/06 ,  A61M16/12 ,  A61M2202/0208 ,  A61M2202/025 ,  A61N1/40 ,  A61N1/44 ,  H01J37/321 ,  H01J37/32348 ,  H01J37/3244 ,  H01J37/3266 ,  H05H1/2406 ,  H05H2001/2412 ,  H05H2001/466 ,  H05H2001/4682 ,  H05H2240/20 ,  H05H2245/1225 ,  H05H2277/10

Abstract: An inhalable cold plasma mask device for generation of a breathable cold plasma for delivery to a patient. A biocompatible gas is received in a dielectric barrier discharge (DBD) device that is energized by an electrode that receives energy from a pulsed source. The DBD device can be grounded by a grounding structure. A grounding screen can be used prior to inhalation of the cold plasma. The inhalable cold plasma mask device includes the use of a single-layer or a two-layer approach to its construction. The inhalable cold plasma mask device can have one or two DBD devices. Such a device and associated method can be used to treat upper respiratory tract infections, as well as reducing inflammation, sinus and esophageal polyps in both size and frequency of occurrence.

Abstract translation: 一种可吸入的冷等离子体掩模装置，用于产生用于输送给患者的透气冷等离子体。 在由从脉冲源接收能量的电极激励的介电阻挡放电（DBD）器件中接收生物相容性气体。 DBD设备可以通过接地结构接地。 在吸入冷等离子体之前可以使用接地屏。 可吸入的冷等离子体掩模装置包括使用单层或双层方法构造。 可吸入的冷等离子体掩模装置可以具有一个或两个DBD装置。 这种装置和相关方法可用于治疗上呼吸道感染，以及减少发生的大小和频率的炎症，窦和食道息肉。

公开(公告)号：WO2012006441A1

公开(公告)日：2012-01-12

申请号：PCT/US2011/043219

申请日：2011-07-07

Applicant: TCI3 - PRESSURE APPLICATIONS, LLC ,  JACOFSKY, Marc, C. ,  JACOFSKY, David, J. ,  PEETERS, John, P.

Inventor： JACOFSKY, Marc, C. ,  JACOFSKY, David, J. ,  PEETERS, John, P.

IPC: A61B5/03

CPC classification number: A61B5/036 ,  A61B5/0031 ,  A61B5/03 ,  A61B5/076 ,  A61B5/4519 ,  A61B5/6828 ,  A61B5/6833 ,  A61B5/6853 ,  A61B5/7275 ,  A61B5/7282 ,  A61B5/746 ,  A61B2562/0247 ,  A61B2562/168 ,  G06F19/00

Abstract: Embodiments of a compartment monitor that can be implanted and left in situ to continuously (or semi-continuously) measure compartment pressures are presented. An exemplary monitor includes a pressure sensor adapted to be implanted in a compartment, a transmitter external to the compartment and coupled to the pressure sensor, and a receiver in communication with the transmitter to receive and process pressure data received from the transmitter. The monitor may also be configured to transmit measured pressure data to a networkable device. The networkable device can then communicate the patient's status and condition to a healthcare provider through a local area network (LAN) or wide area network (WAN). This communication allows the healthcare provider to remotely monitor a patient. The networkable device, or associated computing system, can record and display trends in the pressure data over time, and log the data to the patient's electronic health records.

Abstract translation: 提出了可以植入和留在原位以连续（或半连续）测量隔室压力的隔室监视器的实施例。 示例性监视器包括适于植入隔室中的压力传感器，隔室外部的发射器并耦合到压力传感器，以及与发射器通信的接收器，用于接收和处理从发射器接收的压力数据。 监视器还可以被配置为将测量的压力数据传送到可联网设备。 然后，可联网设备可以通过局域网（LAN）或广域网（WAN）将患者的状态和状况传达给医疗保健提供者。 该通信允许医疗保健提供者远程监视患者。 可联网设备或相关联的计算系统可以随时间记录和显示压力数据的趋势，并将数据记录到患者的电子健康记录中。

公开(公告)号：WO2014093513A1

公开(公告)日：2014-06-19

申请号：PCT/US2013/074437

申请日：2013-12-11

Applicant: COLD PLASMA MEDICAL TECHNOLOGIES, INC. ,  JACOFSKY, Marc C. ,  WATSON, Gregory A.

Inventor： JACOFSKY, Marc C. ,  WATSON, Gregory A.

IPC: A23L3/3409

CPC classification number: A23L3/26 ,  A23B4/015 ,  A23B5/015 ,  A23B7/015 ,  A23B9/06 ,  A23L3/32 ,  A61L2/00 ,  A61L2/14 ,  A61L9/00 ,  H05H1/2406 ,  H05H2001/2431

Abstract: A cold plasma device for killing or reducing a microbiological pathogen, or denaturing a protein in food, in a food processing system using a cold plasma device. The cold plasma device directs a cold plasma at food or a food surface over an effective area for an effective amount of time. The cold plasma device can be a DBD electrode device, or an array of DBD electrode devices. A grounding rod assembly is also described.

Abstract translation: 用于在使用冷等离子体装置的食品加工系统中杀死或减少微生物病原体或使食物中的蛋白质变性的冷等离子体装置。 冷等离子体装置将食物或食物表面上的冷等离子体引导到有效面积上有效的时间。 冷等离子体器件可以是DBD电极器件或DBD电极器件阵列。 还描述了接地棒组件。

公开(公告)号：WO2013040469A1

公开(公告)日：2013-03-21

申请号：PCT/US2012/055595

申请日：2012-09-14

Applicant: COLD PLASMA MEDICAL TECHNOLOGIES, INC. ,  WATSON, Gregory, A. ,  HUMMEL, Robert, M. ,  JACOFSKY, Marc, C. ,  JACOFSKY, David, J.

Inventor： WATSON, Gregory, A. ,  HUMMEL, Robert, M. ,  JACOFSKY, Marc, C. ,  JACOFSKY, David, J.

IPC: A61M35/00

CPC classification number: H05H1/46 ,  A61L2/00 ,  A61L2/0011 ,  A61L2/0094 ,  A61L2/14 ,  A61L2202/11 ,  A61M15/02 ,  A61M16/06 ,  A61M16/12 ,  A61M2202/0208 ,  A61M2202/025 ,  A61N1/40 ,  A61N1/44 ,  H01J37/321 ,  H01J37/32348 ,  H01J37/3244 ,  H01J37/3266 ,  H05H1/2406 ,  H05H2001/2412 ,  H05H2001/466 ,  H05H2001/4682 ,  H05H2240/20 ,  H05H2245/1225 ,  H05H2277/10

Abstract: A nozzle for attachment to a cold plasma device configured to maintain delivery of a stable cold plasma. The nozzle can have many different shaped apertures to support different applications requiring different shaped cold plasma plumes. Use of a disc of foam material within a nozzle can expand the size of aperture of a nozzle while maintaining delivery of a stable cold plasma. The nozzle can be an elongated cannula tube for internal delivery of a cold plasma treatment. The cannula tube can provide an aperture at its distal end or one or more apertures along its length. A shroud can partially enclose the distal aperture of the nozzle. A sterile sleeve can be used in conjunction with a nozzle to provide a sterile means of attachment and operation of the nozzle with a cold plasma device.

Abstract translation: 用于附接到冷等离子体装置的喷嘴，其构造成维持稳定的冷等离子体的输送。 喷嘴可以具有许多不同的形状的孔，以支持需要不同形状的冷等离子体羽流的不同应用。 在喷嘴内使用泡沫材料盘可以扩大喷嘴的孔径尺寸，同时保持输送稳定的冷等离子体。 喷嘴可以是用于冷等离子体处理的内部递送的细长插管管。 插管管可以在其远端处提供一个孔或沿其长度提供一个或多个孔。 护罩可以部分地包围喷嘴的远端孔。 无菌套筒可以与喷嘴一起使用，以提供无菌装置，其与冷等离子体装置连接和操作喷嘴。