Abstract:
A first catheter is dimensioned for deployment within a renal artery. A second catheter has a shaft with an outer diameter smaller than an inner diameter of the first catheter's open lumen. A gap is formed between the shaft and the first catheter when the second catheter is situated within the first catheter. The gap facilitates transport of a fluid, such as imaging contrast media, along the first catheter. An electrode arrangement at the distal end of the shaft is configured to deliver ablative energy to perivascular renal nerves, and has an outer diameter about the same size as the inner diameter of the first catheter such that a fit therebetween substantially blocks fluid flow within the gap yet provides for relative movement between the electrode arrangement and the luminal wall. A conductor extends between the proximal and distal ends of the shaft and is coupled to electrode arrangement.
Abstract:
An ablation catheter includes a flexible shaft having length sufficient to access a patient's renal artery. An electrode arrangement is provided at the distal end of the shaft. A handle unit includes a housing configured for hand-held manipulation and is coupled to the catheter. A battery and one or both of a high frequency AC generator and ultrasound generator are provided in the housing. The battery serves as the sole source of power for the generator. The generator is configured to generate energy sufficient to ablate perivascular renal nerve tissue using energy stored in the battery. The catheter may be disposable and the housing re-usable. Both the catheter and the housing may be disposable.
Abstract:
The present disclosure relates generally to methods and devices for closing and/or sealing an opening in a vessel wall and/or an adjacent tissue tract. In one illustrative embodiment, a device is provided for delivering and deploying an anchor, plug, filament, and/or locking element adjacent to the opening in the vessel wall and/or tissue tract.
Abstract:
Devices, systems, and methods are provided to treat diseased cardiac valves. The device includes a percutaneous heart valve (100) having an expandable valve frame (102) including valve frame members (105), a valve leaflet (132) coupled to the valve frame, and an expandable stent anchoring frame (104) coupled to the valve frame including stent frame members (106) defining a first portion (108) and a second portion (110) having greater flexibility than the first portion, where the first portion and the valve frame define a length, and where the stent frame members and the valve frame members along the length provide a contiguous surface over which a delivery device can repeatedly slide over the length in its entirety in two longitudinal directions when the first portion and the valve frame are in a partially expanded state during delivery from the delivery device.
Abstract:
A device is disclosed foi providing an indication as to the relative position of a vessel or aiteiy opening thereby facilitating the choice of which suturing or plugging technique to thereafter use. A disclosed device includes an outei tube and a collapsible foot slidably disposed within a distal end of the outei tube The foot is connected to a shaft that passes through the tube and exits a proximal end thereof The device may further include one or more threaded suture needles, a biodegradable plug or1 other wound closing device that is connected to another shaft The collapsed or1 folded foot is pushed distally out of the tube and through the opening in the vessel whereupon the foot expands Pulling the expanded foot in the proximal direction provides an indication as to the orientation of the opening in the vessel, which assists in determining the type of closing procedure to be carried out The shaft connected to the foot is preferably connected to an indicator that indicates to the operator or physician that the vessel opening is in one of three positions on the vessel - left, top or right As an alternative, the indicator bar may indicate a relative position in degrees, mm ot μm in deviation from a top stick (or1 top position)
Abstract:
Disclosed herein is an intrathecal catheter (102) having a lumen (112) adapted to transfer liquid between the proximal end of the catheter and its distal end; a pressure detector (116); and a first sealer (120), adapted to seal the catheter against a tissue. Also disclosed herein is a stroke intervention system comprising an intrathecal catheter, an infusate supply chamber (206) in fluid communication with the catheter; a pump (204) in fluid communication with the catheter; and a pressure gauge in fluid cqmmunication with the pressure detector (116).
Abstract:
A cardiac valve with a support frame having a first end member and a second end member opposing the first end member in a substantially fixed distance relationship, and a cover extending over the support frame to allow for unidirectional flow of a liquid through the valve.
Abstract:
Apparatus and methods for forming a conduit through an infarcted region where the conduit is in fluid communication with a supply of oxygenated blood and the venous vasculature and flowing oxygenated blood from the supply of oxygenated blood through the conduit and to the venous vasculature.
Abstract:
A system provides an environmental barrier also useful for providing a circuit, for example, one having a thin-film battery such as one that includes lithium or lithium compounds connected to an electronic circuit. An environmental barrier is deposited as alternating layers, at least one of the layers providing a smoothing, planarizing, and/or leveling physical-configuration function, and at least one other layer providing a diffusion-barrier function. The layer providing the physical-configuration function may include a photoresist, a photodefinable, an energy-definable, and/or a maskable layer. The physical-configuration layer may also be a dielectric. A layered structure, including a plurality of pairs of layers, each pair including a physical configuration layer and a barrier layer with low gas-transmission rates, may be used in reducing gas transmission rate to beyond currently detectable levels.
Abstract:
The present disclosure relates generally to methods and devices for closing and/or sealing an opening in a vessel wall and/or an adjacent tissue tract. In one illustrative embodiment, a device (24) is provided for delivering and deploying an anchor (10), plug (12), suture (14), and/or locking element (16) adjacent to the opening in the vessel wall and/or tissue tract.