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1.发明申请
公开(公告)号：WO2023092089A1
公开(公告)日：2023-05-25
申请号：PCT/US2022/080167
申请日：2022-11-18
发明人： KIM, HoWon J. , KIM, In-San , KIM, Jay S. , KIM, Sun Hwa , KWON, Ick Chan , LEE, Jong Won , YANG, Yoo Soo , YOON, Hong Yeol
摘要： Therapeutic compounds for red blood cell-mediated delivery of an active pharmaceutical ingredient to a target cell are described. The therapeutic compounds are configured to bind CD47 on the surface of a red blood cell and to be subsequently transferred to CD47 on the surface of the target cell, the therapeutic compound ultimately being internalized by the target cell via endocytosis. The target cell may be a cancer cell, a virus-infected cell, or a fibrotic cell.
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2.发明申请
公开(公告)号：WO2023033399A1
公开(公告)日：2023-03-09
申请号：PCT/KR2022/012002
申请日：2022-08-11
发明人： LEE, Myung-Jae
IPC分类号： H01L31/107 , G01J1/44
摘要： A single-photon detection device includes a first well having a first conductivity type, a second well provided on the first well and having a second conductivity type that is different from the first conductivity type, a first depletion forming region provided on the second well and having the first conductivity type, a main depletion region provided between the first well and the second well, and a first sub-depletion region provided between the second well and the first depletion forming region, wherein the first well and the first depletion forming region are spaced apart from each other by the second well.
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公开(公告)号：WO2023006919A1
公开(公告)日：2023-02-02
申请号：PCT/EP2022/071275
申请日：2022-07-28
申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , CENTRE LEON BERARD , UNIVERSITÉ CLAUDE BERNARD LYON 1 , KIST (KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY)
发明人： HENNINO, Ana
摘要： The tumoral stroma evolution during cancer is playing a key role as it may acts as a physical barrier limiting access of the immune cells to the tumor. Thus, βig-h3 (TGFβi) overexpression in the stroma is of bad prognosis in Pancreatic Ductal Adenocarcinoma and in other cancers. A monoclonal antibody against βig-h3 protein called 18B3 was shown playing a role in directly modulating the anti-tumoral immune response by blocking inhibiting CD8+ T cell activation. From 18B3 the inventors developed humanized antibodies having unexpectedly high affinity, slow dissociation rate and strong thermal stability making them powerful candidates for treating cancers wherein the stroma expresses βig-h3 in vivo. The invention thus relates to these humanized monoclonal antibodies and methods of treatment of such cancers.
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4.发明申请
公开(公告)号：WO2022154208A1
公开(公告)日：2022-07-21
申请号：PCT/KR2021/010117
申请日：2021-08-03
发明人： KU, Bon Cheol , HWANG, Jun Yeon , JEONG, Hyeon Su , YOU, Nam Ho , KIM, Nam Dong , KIM, Dae Yoon , LEE, Dong Ju , KIM, Seo Gyun , HONG, Seung Ki , RYU, Seung Woo
摘要： The present disclosure relates to a carbon nanotube fiber having improved physical properties and a method for manufacturing the same. The method according to the present disclosure comprises the steps of: spinning carbon nanotubes with a purity of 90% by weight or more to obtain a first carbon nanotube fiber; and heat-treating the first carbon nanotube fiber at 500 to 3,000 ℃ under an inert gas atmosphere to obtain a second carbon nanotube fiber, wherein the second carbon nanotube fiber has a density of 1.0 to 2.5 g/cm3.
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5.发明申请
公开(公告)号：WO2019009593A2
公开(公告)日：2019-01-10
申请号：PCT/KR2018/007526
申请日：2018-07-03
发明人： CHUNG, Hak Suk , JI, Yu Hyun , AN, Jin Su , KWON, Ick Chan , YANG, Eun Gyeong
摘要： A bacterium that constitutively produces monophosphoryl lipid A (MLA) and a method of producing MLA by using the bacterium may simply produce MLA and a derivative thereof without acid hydrolysis, reduce a probability of natural mutation, and increase yields of MLA and a derivative thereof by constitutive expression of the MLA and derivative thereof.
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公开(公告)号：WO2013058546A1
公开(公告)日：2013-04-25
申请号：PCT/KR2012/008487
申请日：2012-10-17
发明人： PARK, Ji Hyung , YOON, Dong Wook , LEE, Joong Ho
IPC分类号： G06F3/14
CPC分类号： G06F3/017 , G06F3/016 , G06F3/0483 , G06F3/04883 , G06F2203/04808 , G09G2354/00 , G09G2380/14
摘要： Disclosed are a display apparatus and a contents display method. The display apparatus includes: a mobile device tracing information processing unit for receiving position information or orientation information of a mobile device and generating tracing information of the mobile device based on the received position information or orientation information of the mobile device; a gesture processing unit for receiving input information of the mobile device and generating gesture information to change an output format of contents by using the received input information; a rendering unit for generating a predetermined contents image based on the tracing information of the mobile device and the gesture information; and a display unit for displaying the generated contents image.
摘要翻译： 公开了一种显示装置和内容显示方法。 显示装置包括：移动设备跟踪信息处理单元，用于基于接收的移动设备的位置信息或取向信息，接收移动设备的位置信息或取向信息，并生成移动设备的跟踪信息; 手势处理单元，用于接收所述移动装置的输入信息，并且通过使用所接收的输入信息来产生用于改变内容的输出格式的手势信息; 渲染单元，用于基于所述移动设备的跟踪信息和所述手势信息来生成预定内容图像; 以及显示单元，用于显示所生成的内容图像。
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公开(公告)号：WO2013032065A1
公开(公告)日：2013-03-07
申请号：PCT/KR2011/008188
申请日：2011-10-31
申请人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , HAN, Kyoung Ran , PARK, Sang Whan , KIM, Chang Sam , LEE, Hak Man
发明人： HAN, Kyoung Ran , PARK, Sang Whan , KIM, Chang Sam , LEE, Hak Man
IPC分类号： C04B35/10 , C04B35/565 , C04B35/109 , C04B35/01
CPC分类号： C04B35/6303 , C04B35/565 , C04B35/6263 , C04B35/66 , C04B2235/3208 , C04B2235/3217 , C04B2235/3218 , C04B2235/3246 , C04B2235/3418 , C04B2235/3826 , C04B2235/5427 , C04B2235/5436 , C04B2235/5445 , C04B2235/5472 , C04B2235/6562 , C04B2235/6565 , C04B2235/77 , C04B2235/96 , C04B2235/9684
摘要： Disclosed is an unshaped refractory containing a refractory mixture of alumina (Al 2 O 3 ) and silicon carbide (SiC) to which alumina cement, zircon and an alumina binder are added. The refractory exhibits high strength and density as well as significantly improved corrosion resistance, which is due to the reaction of zircon with calcium oxide (CaO), greatly suppressing corrosion by slag. Use of the alumina binder provides fast drying and strength sufficient for handling. Since shrinkage hardly occurs after heat treatment and low porosity and high strength can be obtained, the refractory is very suitable for use, in particular, a gasifier.
摘要翻译： 公开了一种不均匀的耐火材料，其包含氧化铝（Al 2 O 3）和碳化硅（SiC）的耐火混合物，氧化铝水泥，锆石和氧化铝粘结剂被加入到其中。 耐火材料表现出高的强度和密度以及显着提高的耐腐蚀性，这是由于锆石与氧化钙（CaO）的反应，极大地抑制了炉渣的腐蚀。 氧化铝粘结剂的使用提供了快速干燥和足够的强度以进行处理。 由于热处理后几乎不发生收缩，并且可以获得低孔隙率和高强度，耐火材料非常适合用于特别是气化器。
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8.发明申请SPINEL-SILICON CARBIDE REFRACTORY COMPOSITIONS WITH HIGH CORROSION RESISTIVITY TO COAL SLAG AND MANUFACTURING METHOD THEREOF 审中-公开具有高耐腐蚀性的金刚石碳化硅耐火材料组合物及其制造方法
公开(公告)号：WO2013027890A1
公开(公告)日：2013-02-28
申请号：PCT/KR2011/008187
申请日：2011-10-31
申请人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , KIM, Chang-Sam , PARK, Sang Whan , JEON, Sung Woon , LEE, Hak Man
发明人： KIM, Chang-Sam , PARK, Sang Whan , JEON, Sung Woon , LEE, Hak Man
IPC分类号： C04B35/565 , C04B35/567 , C04B35/10 , C04B35/657
CPC分类号： C04B35/443 , C04B35/565 , C04B35/6303 , C04B35/66 , C04B2235/3217 , C04B2235/3218 , C04B2235/3222 , C04B2235/3826 , C04B2235/5427 , C04B2235/5436 , C04B2235/5445 , C04B2235/5472 , C04B2235/77 , C04B2235/95 , C04B2235/96 , C04B2235/9692
摘要： Disclosed is a refractory material for use in a coal gasifier reactor, which has strong resistance to corrosion by coal slag and can be used at high temperatures of 1500 ºC or higher. The disclosed refractory material composition includes: 100 parts by weight of a refractory material which is a mixture of spinel and silicon carbide at a mixing ratio of 25:75-75:25 based on weight; 1-15 parts by weight of submicron-sized α-alumina; and 1-10 parts by weight of boehmite. Since the disclosed refractory material does not contain chromium oxide, it is an environment-friendly refractory material that can be used at high temperatures of 1500 ºC or higher without evaporation of chromium oxide.
摘要翻译： 公开了一种用于煤气化炉反应器的耐火材料，其耐煤腐蚀性强，可在1500℃或更高的高温下使用。 所公开的耐火材料组合物包括：100重量份的基于重量的混合比例为25:75-75:25的尖晶石和碳化硅的混合物的耐火材料; 1-15重量份亚微米级α-氧化铝; 和1-10重量份的勃姆石。 由于公开的耐火材料不含氧化铬，所以它是一种环境友好的耐火材料，可以在1500℃或更高的高温下使用，而不会使氧化铬蒸发。
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9.发明申请
公开(公告)号：WO2013022189A1
公开(公告)日：2013-02-14
申请号：PCT/KR2012/005271
申请日：2012-07-03
申请人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , CHO, Young Sang , KIM, Jae Ik , KIM, Ju Hee , OH, In Hwan , SHIN, Kyung-Ho
发明人： CHO, Young Sang , KIM, Jae Ik , KIM, Ju Hee , OH, In Hwan , SHIN, Kyung-Ho
摘要： The present invention relates to a method of producing hydrogen by splitting water on a solid acid material. Specifically, the method comprises: continuously introducing a water-adsorbed solid acid into a reactor made of a heat-resistant and pressure-resistant material in a state in which the internal temperature of the reactor is maintained at 500~1500 K; splitting the water adsorbed on the solid acid to produce hydrogen; discharging the solid acid used in the splitting of the water from the reactor; adsorbing water on the discharged solid acid; and introducing the water-adsorbed solid acid again into the reactor. According to the invention, the amount of hydrogen produced by splitting of water can be increased by adsorbing a desired amount of water on a solid acid and continuously introducing the water-adsorbed solid acid into a reactor.
摘要翻译： 本发明涉及通过在固体酸性材料上分解水来生产氢的方法。 具体地说，该方法包括：在反应器的内部温度保持在500〜1500K的状态下，将吸水固体酸连续引入由耐热耐压材料制成的反应器中; 分离吸附在固体酸上的水以产生氢; 排出用于从反应器中分离水的固体酸; 将水吸附在排出的固体酸上; 并将吸水固体酸再次引入反应器。 根据本发明，通过将固体酸吸附所需量的水并将吸水的固体酸连续引入反应器，可以提高水分解产生的氢气量。
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公开(公告)号：WO2012161407A1
公开(公告)日：2012-11-29
申请号：PCT/KR2012/001119
申请日：2012-02-15
发明人： KIM, Jinwook , JUNG, Yujin , KANG, Donghoon
CPC分类号： G01B5/004 , A61B5/1114 , A61B5/6822 , A61B5/6823 , A61B5/6824 , A61B5/6825 , A61B5/6828 , A61B5/6829 , A61B5/6831 , A61B2503/10 , A61B2505/09 , G06F3/011
摘要： A motion of a model including a joint, at least one body part that rotates with respect to the joint, and a plurality of inertial sensors attached to each body part and measuring a rotational motion of the body part is tracked by obtaining a rotational matrix of a sensor coordinate system fixed to each of the inertial sensors with respect to an inertial coordinate system fixed to ground, by using a signal measured by the inertial sensor attached to each body part; obtaining a rotational matrix of the sensor coordinate systems with respect to a body part coordinate system fixed to each body part, by using an obtained rotational matrix value of the sensor coordinate system; obtaining a rotational matrix of each body part coordinate system with respect to the inertial coordinate system, by using a calculated rotational matrix of the sensor coordinate systems; and calculating a joint variable with respect to each body part, by using a calculated rotational matrix of the body part coordinate system.
摘要翻译： 包括关节的模型的运动，相对于关节旋转的至少一个身体部分以及附接到每个身体部分并测量身体部位的旋转运动的多个惯性传感器被跟踪，通过获得 通过使用由附接到每个身体部分的惯性传感器测量的信号，相对于固定在地面上的惯性坐标系固定到每个惯性传感器的传感器坐标系; 通过使用获得的传感器坐标系的旋转矩阵值，获得相对于固定到每个身体部位的身体部位坐标系的传感器坐标系的旋转矩阵; 通过使用计算出的传感器坐标系的旋转矩阵获得每个身体部位坐标系相对于惯性坐标系的旋转矩阵; 以及通过使用身体部位坐标系的计算旋转矩阵来计算关于每个身体部位的关节变量。
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