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公开(公告)号：WO2011055897A3
公开(公告)日：2011-10-27
申请号：PCT/KR2010005159
申请日：2010-08-06
发明人： LEE JAE-IL , LEE YOUNG-SUN , LEE TAE-SOO
CPC分类号： C07K16/065 , C07K16/32 , C07K2319/00 , C07K2319/70
摘要： A fusion protein that includes a polypeptide binding specifically to a constant region of an antibody and a stabilization protein linked to a terminus of the polypeptide, a polynucleotide encoding the fusion protein, a cell including the polynucleotide, a method of preparing the fusion protein, and a method of isolating an antibody by using the fusion protein.
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2.发明申请TRIAZOLOPYRIDAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE 审中-公开具有乙酰辅酶A羧酸酶的抑制活性的三唑吡啶衍生物
公开(公告)号：WO2008069500A1
公开(公告)日：2008-06-12
申请号：PCT/KR2007/006136
申请日：2007-11-30
申请人： AMOREPACIFIC CORPORATION , INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY , CRYSTALGENOMICS, INC. , HONG, Yong Deog , KANG, Seung-hyun , KIM, Yeonjoon , BYOUN, Kyoung Hee , WOO, Byoung Young , PARK, Miyoung , JOO, Yung Hyup , KIM, Jung Ju , JANG, Doo Ok , TAE, Jinsung , SHIN, Dongkyu , KIM, Yong Eun , CHEON, Younghoon , LEE, Jae Il , HYUN, Young-Lan , RO, Seonggu , CHO, Joong Myung
发明人： HONG, Yong Deog , KANG, Seung-hyun , KIM, Yeonjoon , BYOUN, Kyoung Hee , WOO, Byoung Young , PARK, Miyoung , JOO, Yung Hyup , KIM, Jung Ju , JANG, Doo Ok , TAE, Jinsung , SHIN, Dongkyu , KIM, Yong Eun , CHEON, Younghoon , LEE, Jae Il , HYUN, Young-Lan , RO, Seonggu , CHO, Joong Myung
IPC分类号： C07D487/04
CPC分类号： C07D487/04
摘要： The present invention relates to a novel triazolopyridazine derivative or a pharmaceutically acceptable salt thereof, and an Acetyl-CoA Carboxylase2 (ACC2) comprising same as an active ingredient. The triazolopyridazine derivative of the present invention effectively inhibits the activity of ACC2 and it may be used for preventing or treating obesity, diabetes, dyslipidemia and diseases related to metabolic syndrome.
摘要翻译： 本发明涉及一种新的三唑并哒嗪衍生物或其药学上可接受的盐，以及含有作为活性成分的乙酰辅酶A羧化酶2（ACC2）。 本发明的三唑并哒嗪衍生物有效抑制ACC2的活性，可用于预防或治疗肥胖症，糖尿病，血脂异常和与代谢综合征有关的疾病。
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3.发明申请TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE 审中-公开具有乙酰辅酶羧酸酶的抑制活性的TRIAZINE衍生物
公开(公告)号：WO2008072850A1
公开(公告)日：2008-06-19
申请号：PCT/KR2007/006192
申请日：2007-12-03
申请人： AMOREPACIFIC CORPORATION , CRYSTALGENOMICS, INC. , INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY of Yonsei University , JOO, Yung Hyup , KANG, Seung-hyun , HONG, Yong Deog , KIM, Yeonjoon , BYOUN, KyoungHee , WOO, Byoung Young , PARK, Miyoung , HA, Jun Yong , KOH, Hyunju , LIM, Kyung Min , KIM, Chae-wook , LEE, Byoung-seok , KIM, Jung Ju , JANG, Doo Ok , TAE, Jinsung , SHIN, Dongkyu , KIM, Yong Eun , LEE, Kyung Ho , LEE, Jae Il , HYUN, Young-Lan , RO, Seonggu , CHO, Joong Myung
发明人： JOO, Yung Hyup , KANG, Seung-hyun , HONG, Yong Deog , KIM, Yeonjoon , BYOUN, KyoungHee , WOO, Byoung Young , PARK, Miyoung , HA, Jun Yong , KOH, Hyunju , LIM, Kyung Min , KIM, Chae-wook , LEE, Byoung-seok , KIM, Jung Ju , JANG, Doo Ok , TAE, Jinsung , SHIN, Dongkyu , KIM, Yong Eun , LEE, Kyung Ho , LEE, Jae Il , HYUN, Young-Lan , RO, Seonggu , CHO, Joong Myung
IPC分类号： C07D413/14 , C07D251/72 , C07D251/02 , C07D215/00 , C07D265/00 , C07D207/00 , C07D221/00 , A61K31/47 , A61K31/53 , A61P7/00
CPC分类号： C07D405/14 , C07D401/04 , C07D401/14 , C07D413/14 , C07D417/14
摘要： The present invention relates to a novel triazine derivative or a pharmaceutically acceptable salt thereof, and an Acetyl-CoA Carboxylase (ACC) comprising same as an active ingredient. The triazine derivative of the present invention effectively inhibits the activity of ACC and it may be used for preventing or treating obesity, diabetes, dyslipidemia and diseases related to metabolic syndrome.
摘要翻译： 本发明涉及一种新型的三嗪衍生物或其药学上可接受的盐，以及含有作为活性成分的乙酰辅酶A羧化酶（ACC）。 本发明的三嗪衍生物有效抑制ACC的活性，可用于预防或治疗肥胖症，糖尿病，血脂异常和与代谢综合征有关的疾病。
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公开(公告)号：WO2011055897A9
公开(公告)日：2011-05-12
申请号：PCT/KR2010/005159
申请日：2010-08-06
发明人： LEE, Jae-Il , LEE, Young-Sun , LEE, Tae-Soo
摘要： A fusion protein that includes a polypeptide binding specifically to a constant region of an antibody and a stabilization protein linked to a terminus of the polypeptide, a polynucleotide encoding the fusion protein, a cell including the polynucleotide, a method of preparing the fusion protein, and a method of isolating an antibody by using the fusion protein.
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5.发明申请FUSION PROTEIN BINDING SPECIFICALLY TO CONSTANT REGION OF ANTIBODY, PREPARATION THEREOF AND METHOD FOR ISOLATING ANTIBODY USING THE SAME 审中-公开融合蛋白特异性结合于抗体的恒定区域，其制备方法和使用相同方法分离抗体的方法
公开(公告)号：WO2011055897A2
公开(公告)日：2011-05-12
申请号：PCT/KR2010005159
申请日：2010-08-06
发明人： LEE JAE-IL , LEE YOUNG-SUN , LEE TAE-SOO
CPC分类号： C07K16/065 , C07K16/32 , C07K2319/00 , C07K2319/70
摘要： A fusion protein that includes a polypeptide binding specifically to a constant region of an antibody and a stabilization protein linked to a terminus of the polypeptide, a polynucleotide encoding the fusion protein, a cell including the polynucleotide, a method of preparing the fusion protein, and a method of isolating an antibody by using the fusion protein.
摘要翻译： 一种融合蛋白，其包含与抗体的恒定区特异性结合的多肽和与该多肽的末端连接的稳定化蛋白，编码该融合蛋白的多核苷酸，包含该多核苷酸的细胞，制备该融合蛋白的方法和 通过使用融合蛋白分离抗体的方法。
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