公开(公告)号：WO2010061396A1

公开(公告)日：2010-06-03

申请号：PCT/IL2009/001127

申请日：2009-11-30

Applicant: ROSETTA GENOMICS LTD. ,  TEL HASHOMER MEDICAL INFRASTRUCTURE AND SERVICES LTD. ,  LEVY, Asaf ,  FREIDMAN, Eitan

Inventor： LEVY, Asaf ,  FREIDMAN, Eitan

IPC: C12Q1/68 ,  A61K31/7088

CPC classification number: C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/178

Abstract: The invention relates to methods for detecting an altered susceptibility to breast and ovarian cancer in a subject carrying a BRCA mutation, comprising determining the nucleic acid sequence of a polymorphism of a microRNA-related gene.

Abstract translation: 本发明涉及用于检测携带BRCA突变的受试者对乳腺和卵巢癌的易感性改变的方法，包括测定微小RNA相关基因的多态性的核酸序列。

公开(公告)号：WO2012066007A1

公开(公告)日：2012-05-24

申请号：PCT/EP2011/070177

申请日：2011-11-15

Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION ,  IBM UNITED KINGDOM LIMITED ,  ARONOVICH, Lior ,  LOYA, Liran ,  LEVY, Asaf

Inventor： ARONOVICH, Lior ,  LOYA, Liran ,  LEVY, Asaf

IPC: G06F12/08 ,  G06F11/20 ,  G06F11/14

CPC classification number: G06F11/2007 ,  G06F3/121 ,  G06F9/3863 ,  G06F9/526 ,  G06F11/1435 ,  G06F11/1471 ,  G06F11/1658 ,  G06F11/1666 ,  G06F11/2023 ,  G06F11/2043 ,  G06F11/2094 ,  G06F12/0813 ,  G06F17/30076 ,  G06F17/30312 ,  G06F2201/82 ,  G06F2201/825 ,  G06F2201/84 ,  G06F2209/523 ,  H04L67/1097

Abstract: Various embodiments for facilitating search, list and retrieval operations on a persistent data set using a distributed shared memory (DSM) by a processor device are provided. In one exemplary embodiment, a DSM is used to store the data structures in a cluster shared memory, such that updates, deletions and insertions are applied to both the persistent data set and the DSM, and search, list and retrieval operations are processed directly from the DSM. A data structure in the persistent data set is stored in two separate DSM pages: a first page includes an identifying search key of the data structure, the search key also pointing to a location of the data structure in the storage. A second page includes the updatable properties of the data structure. A DSM storing the data structures' pages is organized as a two-row matrix.

Abstract translation: 提供了用于利用由处理器设备使用分布式共享存储器（DSM）的持久数据集的搜索，列表和检索操作的各种实施例。 在一个示例性实施例中，DSM用于将数据结构存储在群集共享存储器中，使得更新，删除和插入被应用于持久数据集和DSM两者，并且搜索，列表和检索操作直接从 帝斯曼 持久数据集中的数据结构存储在两个单独的DSM页面中：第一页包括数据结构的识别搜索关键字，搜索关键字还指向存储器中的数据结构的位置。 第二页包括数据结构的可更新属性。 存储数据结构页面的DSM被组织为两行矩阵。

公开(公告)号：WO2011024157A1

公开(公告)日：2011-03-03

申请号：PCT/IL2010/000462

申请日：2010-06-10

Applicant: ROSETTA GENOMICS LTD. ,  SITBON, Einat ,  LITHWICK YANAI, Gila ,  MEIRI, Eti ,  DROMI, Nir ,  LEVY, Asaf

Inventor： SITBON, Einat ,  LITHWICK YANAI, Gila ,  MEIRI, Eti ,  DROMI, Nir ,  LEVY, Asaf

IPC: C07H21/00 ,  A61K31/7088 ,  G01N33/48

CPC classification number: C12N15/113 ,  C12N2310/113 ,  C12N2310/141 ,  C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12Q2600/178

Abstract: Disclosed are microRNA molecules, as well as various nucleic acid molecules relating thereto or derived therefrom Further disclosed are methods and compositions that can be used for diagnosis of cancer.

Abstract translation: 公开了微小RNA分子以及与其相关或衍生的各种核酸分子。进一步公开了可用于诊断癌症的方法和组合物。