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公开(公告)号：WO2008151079A2
公开(公告)日：2008-12-11
申请号：PCT/US2008/065417
申请日：2008-05-30
Applicant: NOVOZYMES, INC. , MERINO, Sandra , MCFARLAND, Keith , CHERRY, Joel , TETER, Sarah
Inventor： MERINO, Sandra , MCFARLAND, Keith , CHERRY, Joel , TETER, Sarah
IPC: C12N1/00
CPC classification number: C12N9/2437 , C12N9/2445 , C12P7/10 , C12P19/02 , C12P19/14 , C12Y302/01004 , C12Y302/01021 , C12Y302/01091 , Y02E50/16 , Y02E50/17 , Y02P20/52
Abstract: The present invention relates to cellulolytic compositions for degrading or converting cellulose-containing material and methods of producing and using the compositions.
Abstract translation: 本发明涉及用于降解或转化含纤维素材料的纤维素分解组合物以及制备和使用该组合物的方法。
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2.发明申请
公开(公告)号：WO2008151043A1
公开(公告)日：2008-12-11
申请号：PCT/US2008/065360
申请日：2008-05-30
Applicant: NOVOZYMES, INC. , MCFARLAND, Keith , HARRIS, Paul
Inventor： MCFARLAND, Keith , HARRIS, Paul
CPC classification number: C12N9/2437 , C12N9/2445 , C12P7/10 , C12P19/02 , C12P19/14 , C12Y302/01004 , C12Y302/01021 , C12Y302/01091 , Y02E50/16 , Y02E50/17 , Y02P20/52
Abstract: The present invention relates to methods of increasing the activity of a polypeptide having cellulolytic enhancing activity, comprising: adding a soluble activating divalent metal cation to a composition comprising the polypeptide having cellulolytic enhancing activity, wherein the presence of the soluble activating divalent metal cation and the polypeptide having cellulolytic enhancing activity increases degradation or conversion of a cellulose-containing material by a cellulolytic enzyme composition compared to the polypeptide having cellulolytic enhancing activity without the soluble activating divalent metal cation. The present invention also relates to compositions, methods for degrading or converting a cellulose-containing material, and methods for producing a fermentation product.
Abstract translation: 本发明涉及增加具有纤维素分解增强活性的多肽的活性的方法，包括：将可溶性活化二价金属阳离子加入到包含具有纤维素分解增强活性的多肽的组合物中，其中可溶性活化二价金属阳离子和 具有纤维素分解增强活性的多肽与不含可溶性活化二价金属阳离子的具有纤维素分解增强活性的多肽相比，通过纤维素分解酶组合物增加了含纤维素材料的降解或转化。 本发明还涉及组合物，降解或转化含纤维素材料的方法，以及用于生产发酵产物的方法。
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公开(公告)号：WO1990013643A2
公开(公告)日：1990-11-15
申请号：PCT/US1990002488
申请日：1990-05-04
Applicant: GENENTECH, INC. , NIKOLICS, Karoly , MCFARLAND, Keith, C. , SEGALOFF, Deborah, L. , SEEBURG, Peter, H.
Inventor： GENENTECH, INC.
IPC: C12N15/12
CPC classification number: C07K16/2869 , A61K38/00 , C07K14/723 , C12N15/85
Abstract: The invention relates to the purification, and cloning of receptors for the luteinizing hormone, choriogonadotropin, follicle stimulating hormone, and thyroid stimulating hormone. The invention additionally concerns the uses for such molecules in the diagnosis and therapy of human conditions.
Abstract translation: 本发明涉及促黄体激素，绒毛膜促性腺激素，促卵泡激素和促甲状腺激素的受体的纯化和克隆。 本发明还涉及这种分子在人类病症的诊断和治疗中的用途。
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公开(公告)号：WO2006125068A3
公开(公告)日：2007-04-12
申请号：PCT/US2006019206
申请日：2006-05-18
Applicant: NOVOZYMES NORTH AMERICA INC , NOVOZYMES INC , SMITH MADS PETER TORRY , COWARD-KELLY GUILLERMA , MCFARLAND KEITH CHARLES , AKERHIELM DEREK SCOTT
Inventor： SMITH MADS PETER TORRY , COWARD-KELLY GUILLERMA , MCFARLAND KEITH CHARLES , AKERHIELM DEREK SCOTT
CPC classification number: C12P21/02
Abstract: The present invention relates to a process of producing desired enzyme(s) in a host cell, comprising cultivating said host cell capable of producing the desired enzyme(s) under conditions conducive for production of the desired enzyme(s) using a substrate for the host cell comprising liquefied and/or saccharified starch-containing plant material.
Abstract translation: 本发明涉及在宿主细胞中产生所需酶的方法，包括在有助于产生所需酶的条件下培养能够产生所需酶的所述宿主细胞， 宿主细胞包含液化和/或糖化淀粉植物材料。
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5.发明申请METHODS OF INHIBITING AA9 LYTIC POLYSACCHARIDE MONOOXYGENASE CATALYZED INACTIVATION OF ENZYME COMPOSITIONS 审中-公开抑制AA9 LYTIC POLYACCHARIDE MONOOXYGENASE催化灭活酶组合物的方法
公开(公告)号：WO2017040907A1
公开(公告)日：2017-03-09
申请号：PCT/US2016/050075
申请日：2016-09-02
Applicant: NOVOZYMES A/S , MCFARLAND, Keith
Inventor： MCFARLAND, Keith , TEJIRIAN, Ani , AKERHIELM, Derek
CPC classification number: C13K1/02 , C12N9/0004 , C12N9/0061 , C12N9/0065 , C12P19/02 , C12P19/14 , C12P2201/00 , C12P2203/00 , C12Y110/03002 , C12Y111/01006 , C12Y302/01004
Abstract: The present invention relates to methods of inhibiting AA9 lytic polysaccharide monooxygenase catalyzed inactivation of an enzyme composition or a component thereof, methods for increasing production of an enzyme composition, and methods for stabilizing an enzyme composition.
Abstract translation: 本发明涉及抑制AA9溶解性多糖单加氧酶催化的酶组合物或其组分失活的方法，增加酶组合物的产生的方法和稳定酶组合物的方法。
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Patent Agency Ranking
公开(公告)号：WO2006125068A2
公开(公告)日：2006-11-23
申请号：PCT/US2006/019206
申请日：2006-05-18
Applicant: NOVOZYMES NORTH AMERICA, INC , NOVOZYMES, INC. , SMITH, Mads Peter Torry , COWARD-KELLY, Guillerma , MCFARLAND, Keith Charles , AKERHIELM, Derek Scott
Inventor： SMITH, Mads Peter Torry , COWARD-KELLY, Guillerma , MCFARLAND, Keith Charles , AKERHIELM, Derek Scott
CPC classification number: C12P21/02
Abstract: The present invention relates to a process of producing desired enzyme(s) in a host cell, comprising cultivating said host cell capable of producing the desired enzyme(s) under conditions conducive for production of the desired enzyme(s) using a substrate for the host cell comprising liquefied and/or saccharified starch-containing plant material.
Abstract translation: 本发明涉及一种在宿主细胞中产生所需酶的方法，包括在有助于生产所需酶的条件下培养能够产生所需酶的所述宿主细胞， 宿主细胞包含液化和/或糖化淀粉植物材料。
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7.发明申请
公开(公告)号：WO2011008785A3
公开(公告)日：2011-03-17
申请号：PCT/US2010041869
申请日：2010-07-13
Applicant: NOVOZYMES AS , MALTEN MARCO , MCFARLAND KEITH
Inventor： MALTEN MARCO , MCFARLAND KEITH
IPC: G01N33/50
CPC classification number: C12Q1/34 , G01N2333/924
Abstract: Enzymes and/or polypeptides and/or mixtures of interest are evaluated during hydrolysis of cellulosic material by the use of indicator constituents such as fluorescent agents, resulting in efficient high-throughput analysis of enzymes and/or polypeptides. A high-throughput assay for the analysis of, inter alia, pretreated corn stover (PCS) hydrolysis is also disclosed.
Abstract translation: 通过使用诸如荧光剂的指标成分，在纤维素材料的水解期间评估感兴趣的酶和/或多肽和/或混合物，从而导致酶和/或多肽的有效的高通量分析。 还公开了用于分析预处理的玉米秸秆（PCS）水解的高通量测定。
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8.发明申请
公开(公告)号：WO2011008785A2
公开(公告)日：2011-01-20
申请号：PCT/US2010/041869
申请日：2010-07-13
Applicant: NOVOZYMES A/S , MALTEN, Marco , MCFARLAND, Keith
Inventor： MALTEN, Marco , MCFARLAND, Keith
IPC: G01N33/50
CPC classification number: C12Q1/34 , G01N2333/924
Abstract: Enzymes and/or polypeptides and/or mixtures of interest are evaluated during hydrolysis of cellulosic material by the use of indicator constituents such as fluorescent agents, resulting in efficient high-throughput analysis of enzymes and/or polypeptides. A high-throughput assay for the analysis of, inter alia, pretreated corn stover (PCS) hydrolysis is also disclosed.
Abstract translation: 通过使用指示剂组分（例如荧光剂）在纤维素材料的水解期间评估酶和/或多肽和/或感兴趣的混合物，导致酶和/或多肽的有效高通量分析 。 还公开了用于分析预处理的玉米秸秆（PCS）水解的高通量测定。
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公开(公告)号：WO2008151079A3
公开(公告)日：2009-04-23
申请号：PCT/US2008065417
申请日：2008-05-30
Applicant: NOVOZYMES INC , MERINO SANDRA , MCFARLAND KEITH , CHERRY JOEL , TETER SARAH
Inventor： MERINO SANDRA , MCFARLAND KEITH , CHERRY JOEL , TETER SARAH
CPC classification number: C12N9/2437 , C12N9/2445 , C12P7/10 , C12P19/02 , C12P19/14 , C12Y302/01004 , C12Y302/01021 , C12Y302/01091 , Y02E50/16 , Y02E50/17 , Y02P20/52
Abstract: The present invention relates to cellulolytic compositions for degrading or converting cellulose-containing material and methods of producing and using the compositions. The compositions comprise (a) a polypeptide having cellulolytic enhancing activity (b) a beta glucosidase and (c) one or more cellulolytic enzymes selected from the group consisting of T. reesei cellohydrobiolase I T. reesei cellohydrobiolase II and T. reseei endoglucanase I and variants thereof.
Abstract translation: 本发明涉及用于降解或转化含纤维素材料的纤维素分解组合物以及制备和使用该组合物的方法。 组合物包含（a）具有纤维素分解增强活性的多肽（b）β葡糖苷酶和（c）一种或多种纤维素分解酶，其选自里氏木霉纤维素水解酶I.里氏木霉纤维素酶II和T.revisi内切葡聚糖酶I和 其变体。
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10.发明申请COMPOSITIONS AND METHODS FOR ENHANCING THE DEGRADATION OR CONVERSION OF CELLULOSE-CONTAINING MATERIAL 审中-公开用于增强含有纤维素的材料的降解或转化的组合物和方法
公开(公告)号：WO2008140749A3
公开(公告)日：2009-01-15
申请号：PCT/US2008005927
申请日：2008-05-09
Applicant: NOVOZYMES INC , MCFARLAND KEITH
Inventor： MCFARLAND KEITH
CPC classification number: C12P13/20 , C12N9/2437 , C12N9/2445 , C12P5/023 , C12P7/06 , C12P7/14 , C12P7/24 , C12P7/26 , C12P19/14 , C12P2201/00 , C12P2203/00 , C12Y302/01004 , C12Y302/01021 , C12Y302/01091 , Y02E50/16 , Y02E50/17 , Y02E50/343 , Y02P20/52
Abstract: The present invention relates to methods for degrading or converting a cellulose-containing material, comprising: treating the cellulose-containing material with an effective amount of a cellulolytic enzyme composition comprising a polypeptide having cellulolytic enhancing activity, and one or more (several) components selected from the group consisting of a CEL7 polypeptide having endoglucanase activity, a CEL12 polypeptide having endoglucanase activity, a CEL45 polypeptide having endoglucanase activity, a CEL7 polypeptide having cellobiohydrolase activity with a cellulose binding domain, and a CEL7 polypeptide having cellobiohydrolase activity without a cellulose binding domain. The present invention also relates to such cellulolytic enzyme compositions.
Abstract translation: 本发明涉及降解或转化含纤维素材料的方法，其包括：用有效量的包含具有纤维素分解增强活性的多肽的纤维素分解酶组合物和选择的一种或多种（若干）组分处理含纤维素材料 由具有内切葡聚糖酶活性的CEL7多肽，具有内切葡聚糖酶活性的CEL12多肽，具有内切葡聚糖酶活性的CEL45多肽，具有纤维素结合结构域的纤维二糖水解酶活性的CEL7多肽和不含纤维素结合结构域的纤维二糖水解酶活性的CEL7多肽 。 本发明还涉及这种纤维素分解酶组合物。
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