公开(公告)号：WO2014200786A1

公开(公告)日：2014-12-18

申请号：PCT/US2014/040983

申请日：2014-06-05

Applicant: MERCK SHARP & DOHME CORP. ,  MILLER, Steven, P. ,  LIMANTO, John ,  ZHONG, Yong-Li ,  YASUDA, Nobuyoshi ,  LIU, Zhijian

Inventor： MILLER, Steven, P. ,  LIMANTO, John ,  ZHONG, Yong-Li ,  YASUDA, Nobuyoshi ,  LIU, Zhijian

IPC: C07D491/02 ,  C07D211/00

CPC classification number: C07D471/08 ,  C07D211/62 ,  C07D401/12 ,  C07D491/08 ,  Y02P20/55

Abstract: A process for the preparation of N-protected 6-(piperidin-4-ylcarbamoyl)piperidin-3-yl sulfonates of Formula (III): which comprises contacting a lactone of Formula (II): with an azacycloalkylamine of formula (II-Am): followed by contact with a sulfonyl halide of formula (II-Su): R 4 -SO 2 W (II-Su) in the presence of tertiary amine base, wherein P G1 and P G2 are amine protective groups; k, p and q are 0, 1, or 2, and W, R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , and R 9 are defined herein. Additional embodiments add a series of process steps leading to the synthesis of 7-oxo-1,6-diazabicyclo[3.2.1]octanes suitable for use as β-lactamase inhibitors.

Abstract translation: 制备式（III）的N-保护的6-（哌啶-4-基氨基甲酰基）哌啶-3-基磺酸盐的方法：其包括使式（II）的内酯与式（II-Am）的氮杂环烷基胺 ）：在叔胺碱的存在下与式（II-Su）的磺酰卤接触：R4-SO2W（II-Su），其中PG1和PG2是胺保护基; k，p和q分别为0,1或2，W，R2，R3，R4，R5，R6，R7，R8和R9如本文所定义。 另外的实施方案添加了一系列方法步骤，导致合成适合用作β-内酰胺酶抑制剂的7-氧代-1,6-二氮杂双环[3.2.1]辛烷。

公开(公告)号：WO2012178017A9

公开(公告)日：2013-02-28

申请号：PCT/US2012043759

申请日：2012-06-22

Applicant: CARTRIDGE CORP OF AMERICA INC ,  MILLER STEVEN ,  SCHNELL HERMAN

Inventor： MILLER STEVEN ,  SCHNELL HERMAN

IPC: G03G21/16

CPC classification number: G03G15/55 ,  G03G15/553 ,  G03G21/1676 ,  G03G2221/1663 ,  G03G2221/1823

Abstract: An electronic circuit for use with a consumable imaging unit comprises information configured to transform said electronic circuit from a communicated state to a non communicated state. Additionally, the information of the circuit is configured to alter an identifier of the circuit. The information of the circuit is also configured to point an imaging machine to communicate with a second element of the circuit after the information determines that a first element of the circuit has been altered from its original state.

Abstract translation: 用于消耗成像单元的电子电路包括被配置为将所述电子电路从通信状态转换为非通信状态的信息。 此外，电路的信息被配置为改变电路的标识符。 电路的信息还被配置为在信息确定电路的第一元件已经从其原始状态改变之后，将成像机指向与电路的第二元件通信。

公开(公告)号：WO2012064319A1

公开(公告)日：2012-05-18

申请号：PCT/US2010/055764

申请日：2010-11-08

Applicant: COLGATE-PALMOLIVE COMPANY ,  MILLER, Steven ,  XU, Guofeng ,  FEI, Lin ,  YANG, Ying ,  JARACZ, Stanislav

Inventor： MILLER, Steven ,  XU, Guofeng ,  FEI, Lin ,  YANG, Ying ,  JARACZ, Stanislav

IPC: A61K8/04 ,  A61K8/27 ,  A61K8/49 ,  A61K8/73 ,  A61K8/86 ,  A61Q11/00

CPC classification number: A61K8/11 ,  A61K8/0275 ,  A61K8/27 ,  A61K8/4993 ,  A61K8/731 ,  A61K8/86 ,  A61K2800/412 ,  A61Q11/00

Abstract: The invention relates to a composite and oral care compositions for use in the mouth to retard the accumulation of dental plaque and/or calculus. The composite is a microaggregate comprising polymer coated, surfactant stabilized particles of a substantially insoluble metal, metal salt or metal oxide, for example zinc oxide. Also methods for retarding the accumulation of dental plaque and/or calculus are provided.

Abstract translation: 本发明涉及一种用于口腔的复合和口腔护理组合物，以阻止牙菌斑和/或结石的积聚。 该复合物是包含聚合物涂覆的表面活性剂稳定的基本上不溶的金属，金属盐或金属氧化物的颗粒，例如氧化锌的微粒聚集体。 还提供了用于延缓牙斑和/或结石积聚的方法。

公开(公告)号：WO2011088387A3

公开(公告)日：2011-10-13

申请号：PCT/US2011021389

申请日：2011-01-14

Applicant: SALIENT SURGICAL TECH INC ,  BLOOM ELIOT F ,  CONLEY BRIAN M ,  BARRY JONATHAN J ,  GREELEY ROGER D ,  MILLER STEVEN G ,  GREENLAW CHAD M

Inventor： BLOOM ELIOT F ,  CONLEY BRIAN M ,  BARRY JONATHAN J ,  GREELEY ROGER D ,  MILLER STEVEN G ,  GREENLAW CHAD M

IPC: A61B18/14 ,  A61B17/00 ,  A61B18/08 ,  A61M25/00 ,  A61M39/10 ,  H01R13/00 ,  H01R13/52 ,  H01R13/62

CPC classification number: A61B18/1206 ,  A61B17/1664 ,  A61B17/1671 ,  A61B17/1675 ,  A61B17/1684 ,  A61B18/082 ,  A61B18/14 ,  A61B18/1402 ,  A61B2017/00261 ,  A61B2018/00178 ,  A61B2018/00928 ,  A61B2018/0094 ,  A61B2018/00958 ,  A61B2018/00988 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1412 ,  A61B2018/1415 ,  A61B2018/1472 ,  A61B2218/002

Abstract: A cartridge assembly to couple an electrosurgical device to treat tissue with an electro surgical unit includes a cartridge member to operate with a power delivery apparatus of the electrosurgical unit and a fluid delivery apparatus of the electrosurgical unit. An electrosurgical unit includes a power delivery apparatus and a fluid delivery apparatus arranged to operate with a cartridge member to be located in a cartridge receptacle of the electrosurgical unit. An electrosurgical device includes a first electrode spaced alongside the second electrode, with each electrode having a blade shaped member. Each blade shaped member has opposing sides bounded by edges, with the edges having a medial edge and a lateral edge. At least one fluid outlet is adjacent each blade shaped member, and each fluid outlet is in fluid communication with a fluid passage. The device can be operated as either a bipolar device or a monopolar device and includes a switch to inhibit capacitive coupling to one of the electrodes when the other electrode is used in monopolar fashion.

Abstract translation: 将电外科装置联接以用电手术单元处理组织的药筒组件包括用电外科手术单元的动力输送装置和电外科手术单元的流体输送装置操作的药筒构件。 电外科单元包括动力输送装置和流体输送装置，该装置布置成与待置入电外科单元的药筒容器中的药筒构件一起操作。 电外科装置包括与第二电极隔开的第一电极，每个电极具有叶片形状的构件。 每个叶片形构件具有由边缘限定的相对侧，边缘具有中间边缘和侧边缘。 至少一个流体出口邻近每个叶片形状构件，并且每个流体出口与流体通道流体连通。 该器件可以作为双极器件或单极器件工作，并且当另一个电极以单极方式使用时，该开关可以抑制电容耦合到电极之一。

公开(公告)号：WO2009132105A3

公开(公告)日：2009-10-29

申请号：PCT/US2009/041407

申请日：2009-04-22

Applicant: VONAGE NETWORK LLC ,  OTTUR, Deepak ,  RILEY, John ,  MAMAKOS, Louis ,  MILLER, Steven, Douglas

Inventor： OTTUR, Deepak ,  RILEY, John ,  MAMAKOS, Louis ,  MILLER, Steven, Douglas

IPC: H04L12/26 ,  H04L12/66 ,  H04L29/06

Abstract: Method and apparatus for testing in a communication network is described. One example of the invention relates to a method of testing in a voice over internet protocol (VOIP) network. At least one test script is obtained from the VOIP network at an enhanced terminal adapter. The enhanced terminal adapter is configured to couple at least one communication device to the VOIP network. The at least one test script is executed within a scripting framework of the enhanced terminal adapter to interact with at least one component coupled to the VOIP network. Results of the execution of the at least one test script are transmitted from the enhanced terminal adapter to the VOIP network.

公开(公告)号：WO2009086448A1

公开(公告)日：2009-07-09

申请号：PCT/US2008/088294

申请日：2008-12-24

Applicant: SALIENT SURGICAL TECHNOLOGIES, Inc. ,  GREELEY, Roger, D. ,  MILLER, Steven, G. ,  PODANY, Vaclav, O. ,  CONLEY, Brian, M. ,  GREENLAW, Chad, M.

Inventor： GREELEY, Roger, D. ,  MILLER, Steven, G. ,  PODANY, Vaclav, O. ,  CONLEY, Brian, M. ,  GREENLAW, Chad, M.

IPC: A61F2/00

CPC classification number: A61B18/1402 ,  A61B2018/00136 ,  A61B2018/126 ,  A61B2018/1472 ,  A61B2090/306 ,  A61B2090/309 ,  A61B2218/002

Abstract: The invention provides a bipolar electrosurgical device to treat tissue in a presence of radio frequency energy and a fluid provided from the device. In one embodiment, the device comprises a first electrode and a second electrode at the end of a malleable shaft assembly to be hand shapeable by a user of the device, and at least one fluid outlet. The malleable shaft assembly comprises a first shaft and a second shaft, a length of the first shaft and a length of the second shaft in an outer member comprising a polymer, and at least a portion of the first shaft and at least a portion of the second shaft being malleable.

Abstract translation: 本发明提供一种双极电外科装置，用于在存在无线电频率能量和从该装置提供的流体的情况下处理组织。 在一个实施例中，该装置包括第一电极和第二电极，该第一电极和第二电极位于可延展的轴组件的端部，以由该装置的使用者手形地形成，以及至少一个流体出口。 可延展的轴组件包括第一轴和第二轴，第一轴的长度和包括聚合物的外部构件中的第二轴的长度，以及第一轴的至少一部分和第一轴的至少一部分 第二轴可延展。

公开(公告)号：WO2009062891A1

公开(公告)日：2009-05-22

申请号：PCT/EP2008/065140

申请日：2008-11-07

Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION ,  IBM UNITED KINGDOM LIMITED ,  ALLEN JR, Lloyd ,  JENKINS, Jana, Helton ,  MILLER, Steven, Michael

Inventor： ALLEN JR, Lloyd ,  JENKINS, Jana, Helton ,  MILLER, Steven, Michael

IPC: G06F9/44

CPC classification number: G06F9/453

Abstract: Enabling end users to add their own hover help to extend hover help that is provided in a user interface, without having access to the code of the application. An end user can extend the application-provided hover help information to make it more helpful or tailored to his own needs. The originally-provided hover help is retained, and may be rendered in addition to the user's appended hover help. Or, by specifying that the user-provided hover help is displayed in the same location as the originally-provided hover help, the user-provided hover help can be rendered such that the originally-provided hover help is at least partially obscured.

Abstract translation: 使最终用户能够添加自己的悬浮帮助，以扩展用户界面中提供的悬停帮助，而无需访问应用程序的代码。 最终用户可以扩展应用程序提供的悬停帮助信息，使其更有用或适合自己的需求。 原来提供的悬停帮助是保留的，除了用户的附加悬停帮助之外，还可以提供它。 或者，通过指定用户提供的悬停帮助显示在与原始提供的悬停帮助相同的位置，用户提供的悬停帮助可以被渲染，使得原来提供的悬停帮助至少部分地被遮蔽。

公开(公告)号：WO2007066242A3

公开(公告)日：2009-04-16

申请号：PCT/IB2006052788

申请日：2006-08-11

Applicant: MILLER STEVEN

Inventor： MILLER STEVEN

IPC: F01K1/00

CPC classification number: F01K9/003

Abstract: The combined circulation condenser will increase the overall efficiency of a steam plant. Less fuel will be consumed for a given power level. It has become increasingly important to conserve fuel and resources. This is true with power generation plants, as well as propulsion plants, Civilian, as well as Military. This combined circulation condenser will do just that.

Abstract translation: 联合循环冷凝器将提高蒸汽设备的整体效率。 在给定的功率水平下，燃料消耗将减少。 节约燃料和资源变得越来越重要。 对于发电厂以及推进装置，平民以及军人来说都是如此。 这种联合循环冷凝器将做到这一点。

公开(公告)号：WO2005098549A3

公开(公告)日：2008-11-13

申请号：PCT/US2005011160

申请日：2005-04-01

Applicant: MILLER STEVEN

Inventor： MILLER STEVEN

IPC: G03G21/18 ,  G03G15/08

CPC classification number: G03G21/12 ,  G03G15/0856 ,  G03G15/0862 ,  G03G15/0889 ,  G03G21/181 ,  G03G21/1821 ,  G03G2215/085 ,  G03G2215/0888

Abstract: A toner cartridge (1) includes a waste bin (10) having a leading end that can be sculpted to mate with the cartridge-receiving cavities and an improved toner beater and sensing apparatus (40), the elimination of a pivotal motion between the elements of the cartridge, an enhanced method of determining the amount of toner remaining in the toner chamber, and an improved means of agitating the toner within the toner chamber.

Abstract translation: 调色剂盒（1）包括具有前端的垃圾箱（10），该前端可被雕刻以与盒接收腔配合，以及改进的调色剂搅拌器和感测装置（40），消除了元件之间的枢转运动 的墨盒，确定调色剂室中残留的调色剂量的增强方法，以及搅拌调色剂室内调色剂的改进方法。

公开(公告)号：WO2007078784A3

公开(公告)日：2008-09-25

申请号：PCT/US2006047593

申请日：2006-12-14

Applicant: PESA SWITCHING SYSTEMS INC ,  ELLGEN DAVID LESLIE ,  BOND HARLAN KEITH ,  MILLER STEVEN

Inventor： ELLGEN DAVID LESLIE ,  BOND HARLAN KEITH ,  MILLER STEVEN

IPC: H04N7/01 ,  H04N5/268

CPC classification number: H04N5/268

Abstract: A system for performing signal processing includes a system input, wherein a first signal having a first format, and supplied on a first system input is selected by a user for format conversion. A switching circuit having plural switching circuit inputs and. plural switching circuit outputs is provided for routing the first signal, received via a first switching circuit input, to a first switching circuit output. A processor is connected with the switching circuit for converting the first signal received via the first switching circuit output into a second signal having a second format, wherein the second signal is supplied to a second switching circuit input, and output to a first system output via a second switching circuit output.

Abstract translation: 用于执行信号处理的系统包括系统输入，其中由用户选择具有第一格式并在第一系统输入上提供的第一信号进行格式转换。 一种开关电路，具有多个开关电路输入端。 提供多个开关电路输出用于将经由第一开关电路输入接收的第一信号路由到第一开关电路输出。 处理器与切换电路连接，用于将经由第一切换电路输出接收的第一信号转换成具有第二格式的第二信号，其中第二信号被提供给第二开关电路输入，并经由 第二开关电路输出。