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    CONJUGATE HAVING CLEAVABLE LINKING AGENT
    1.
    发明申请
    CONJUGATE HAVING CLEAVABLE LINKING AGENT 审中-公开
    具有可清洗连接剂的连接

    公开(公告)号：WO2010135330A1

    公开(公告)日：2010-11-25

    申请号：PCT/US2010/035265

    申请日：2010-05-18

    Applicant: ABBOTT LABORATORIES ,  KONRATH, John G. ,  MOORE, Jeffrey A. ,  HIMMELSBACH, Richard J.

    Inventor： KONRATH, John G. ,  MOORE, Jeffrey A. ,  HIMMELSBACH, Richard J.

    IPC: G01N33/532 ,  G01N33/543 ,  G01N33/58

    CPC classification number: G01N33/54333 ,  G01N33/582

    Abstract: A method and reagent that can be used to eliminate the signal caused by non-specific binding of a labeled conjugate, e.g., a specific binding member attached to a label, to a solid phase, e.g., a magnetic microparticle. The method and the reagent involve the use of a cleavable linking agent to link the label to the specific binding member that specifically binds to the analyte. The use of a cleavable linking agent would allow the release of the label from the specific binding member from the complex comprising the magnetic microparticle, analyte, and labeled conjugate into solution. After the release of the label, the magnetic microparticles having any label non-specifically bound thereto, are removed from the reaction mixture. Only the label, e.g., acridinium, from the labeled conjugate would remain in the elution well. The conjugate that is non-specifically bound through interaction between the label and the solid phase, e.g., a magnetic particle, would remain bound to the solid phase, and would subsequently be removed from the elution well when the solid phase is removed from the elution well and transferred to another well the introduction of additional reagent(s).

    Abstract translation: 可用于消除由标记的缀合物（例如附着于标记物的特异性结合构件）与固相例如磁性微粒的非特异性结合引起的信号的方法和试剂。 该方法和试剂包括使用可切割的连接剂将标记物与特异性结合分析物结合的特异性结合成员连接。 使用可切割交联剂将允许从包含磁性微粒，分析物和标记的缀合物的络合物中将标记从特异性结合成员释放到溶液中。 剥离标签后，从反应混合物中除去具有非特异性结合的标记的磁性微粒。 只有来自标记的缀合物的标记（例如吖啶鎓）将保留在洗脱井中。 通过标记和固相（例如磁性颗粒）之间的相互作用非特异性结合的缀合物将保持与固相结合，并且随后在从洗脱液中除去固相时从洗脱孔中除去 并转移到另一个井，引入额外的试剂。

    ARC-EXTINGUISHING COMPOSITION AND ARTICLES MANUFACTURED THEREFROM
    5.
    发明申请
    ARC-EXTINGUISHING COMPOSITION AND ARTICLES MANUFACTURED THEREFROM 审中-公开
    ARC-EXTINGUISHING组合物及由其制造的制品

    公开(公告)号：WO2006016932B1

    公开(公告)日：2006-04-06

    申请号：PCT/US2005017100

    申请日：2005-05-16

    Applicant: S & C ELECTRIC CO ,  MOORE JEFFREY A

    Inventor： MOORE JEFFREY A

    IPC: H01H85/42 ,  H01H33/73 ,  H01H33/76

    CPC classification number: H01H85/42 ,  H01H9/302 ,  H01H33/76 ,  H01H2085/388

    Abstract: An arc-interrupting compound, such as melamine, and to a method of extinguishing an arc by disposing the composition along the path of the arc, for contacting the arc. In one embodiment, the binder, or at least a portion of the binder, is a polymer that contains a functional group that binds to a coupling agent that is included in the arc-extinguishing composition. The coupling agent ties the polymeric binder to the arc-extinguishing compound,

    Abstract translation: 一种阻断电弧的化合物，如三聚氰胺，还涉及一种通过沿着电弧路径放置组合物以熄灭电弧以接触电弧的方法。 在一个实施方案中，粘合剂或粘合剂的至少一部分是含有与包含在灭弧组合物中的偶联剂结合的官能团的聚合物。 偶联剂将聚合物粘合剂连接到灭弧化合物上，

    ARC-EXTINGUISHING COMPOSITION AND ARTICLES MANUFACTURED THEREFROM
    6.
    发明申请
    ARC-EXTINGUISHING COMPOSITION AND ARTICLES MANUFACTURED THEREFROM 审中-公开
    灭弧组合物及其制造的制品

    公开(公告)号：WO2006016932A1

    公开(公告)日：2006-02-16

    申请号：PCT/US2005/017100

    申请日：2005-05-16

    Applicant: S & C ELECTRIC CO. ,  MOORE, Jeffrey, A.

    Inventor： MOORE, Jeffrey, A.

    IPC: H01H85/42 ,  H01H33/73

    CPC classification number: H01H85/42 ,  H01H9/302 ,  H01H33/76 ,  H01H2085/388

    Abstract: An arc-interrupting compound, such as melamine, and to a method of extinguishing an arc by disposing the composition along the path of the arc, for contacting the arc. In one embodiment, the binder, or at least a portion of the binder, is a polymer that contains a functional group that binds to a coupling agent that is included in the arc-extinguishing composition. The coupling agent ties the polymeric binder to the arc-extinguishing compound, e.g. , melamine, to provide new and unexpected physical strength and stability to the composition. In this embodiment, the molded composition, including the arc-interrupting compound coupled to the binder, maintains excellent arc-interrupting capability, while providing chemical stability and electrical insulating properties as well as unexpected physical strength.

    Abstract translation: 一种电弧中断化合物，例如三聚氰胺，以及通过沿着电弧的路径设置组合物以消除电弧的方法，用于接触电弧。 在一个实施方案中，粘合剂或粘合剂的至少一部分是含有与包含在灭弧组合物中的偶联剂结合的官能团的聚合物。 偶联剂将聚合物粘合剂与灭弧化合物

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