公开(公告)号：WO2017083770A1

公开(公告)日：2017-05-18

申请号：PCT/US2016/061696

申请日：2016-11-11

申请人： ONEFOCUS VISION, INC.

发明人： HARANT, Adam ,  CRAMER, Neil ,  DAVENPORT, Amelia ,  WAITE, Steve ,  GUPTA, Amitava

IPC分类号： B29D11/00 ,  G02C7/04

CPC分类号： B29D11/00 ,  B29D11/00028 ,  B29D11/00048 ,  B29D11/00067 ,  G02B1/043 ,  G02C7/04 ,  C08L33/10

摘要： A hydrogel formulation has been developed that can be cast to form a hydrophilic cross-linked network with water content of 30-60% by weight that undergoes a volume expansion less than 5% when equilibrated in water or an aqueous solution of ionic species. This hydrogel formulation was used to cast a soft contact lens incorporating an insert that may be a sealed module filled with a fluid. Diameter of lenses cast without an insert measured within 0.5-5.0%) of the target diameter after hydration. The interface between the hydrogel and the insert in lenses cast with an insert remaining stress free after hydration, when the lens was inspected under a microscope. The formulation comprises and may consist of a mixture of hydrophilic mono-functional monomers, cross-linking agents, a photo-curing catalyst and a diluent.

摘要翻译： 已经开发了一种水凝胶制剂，其可以浇注以形成水含量为30-60重量％的亲水性交联网络，其在水中平衡时经历小于5％的体积膨胀或 离子物质的水溶液。 使用该水凝胶制剂来铸造包含插入物的软性隐形眼镜，该插入物可以是填充有流体的密封模块。 在没有插入物的情况下铸造的透镜的直径在水合后在0.5-5.0％的目标直径内测量。 当透镜在显微镜下检查时，水凝胶和插入物之间的界面与水合后保持无应力的插入物一起铸造。 该制剂包含亲水性单官能单体，交联剂，光固化催化剂和稀释剂的混合物并可由其组成。

公开(公告)号：WO2017083774A1

公开(公告)日：2017-05-18

申请号：PCT/US2016/061700

申请日：2016-11-11

申请人： ONEFOCUS VISION, INC. ,  WAITE, Steve

发明人： WAITE, Steve ,  HARANT, Adam ,  DAVENPORT, Amelia ,  CRAMER, Neil ,  GUPTA, Amitava ,  LINK, William J. ,  ALKHIMI, Gamil ,  STUDNICKI, Lisa ,  ALHAKIMI, Musa

IPC分类号： B29C39/12 ,  B29C41/22 ,  B29D11/00 ,  B29L11/00 ,  C08J3/24 ,  G02B1/04 ,  G02C7/04

CPC分类号： G02C7/049 ,  B29C39/021 ,  B29C39/10 ,  B29C39/12 ,  B29C41/22 ,  B29D11/00 ,  B29D11/00038 ,  B29D11/00048 ,  B29D11/00125 ,  B29D11/00134 ,  B29K2105/0002 ,  B29K2105/0035 ,  B29K2105/20 ,  B29K2629/04 ,  B29K2995/0059 ,  B29L2011/0041 ,  G02B1/04 ,  G02B1/043 ,  G02C7/04 ,  G02C7/048 ,  G02C7/085 ,  C08L101/14 ,  C08L33/10 ,  C08L33/26

摘要： A lens comprises an internal cavity structure formed by dissolution of a soluble insert material. The internal soluble material may dissolve through a body of a lens such as a contact lens in order to form the cavity within the contact lens. The cavity within the lens can be shaped in many ways, and corresponds to the shape of the dissolved material, such that many internal cavity shapes can be readily fabricated within the contact lens. The insert can be placed in a mold with a pre-polymer material, and the pre-polymer material cured with the insert placed in the mold to form the lens body. The polymerized polymer may comprise a low expansion polymer in order to inhibit expansion of the lens when hydrated. The polymer may comprise a hydrogel when hydrated. The soft contact lens material comprises a sufficient amount of cross-linking to provide structure to the lens and shape the cavity.

摘要翻译： 透镜包括通过溶解可溶性插入材料形成的内腔结构。 内部可溶性材料可通过例如隐形眼镜的镜片主体溶解，以在隐形眼镜内形成腔。 透镜内的空腔可以以许多方式成形，并且对应于溶解材料的形状，使得很多内部空腔形状可以容易地制造在隐形眼镜内。 插入物可以放置在具有预聚合物材料的模具中，并且将插入物置于模具中固化的预聚物材料形成镜体。 聚合的聚合物可以包含低膨胀聚合物以抑制透镜在水合时膨胀。 当水合时，聚合物可以包含水凝胶。 软性隐形眼镜材料包含足够量的交联以为透镜提供结构并形成空腔。

公开(公告)号：WO2015095891A1

公开(公告)日：2015-06-25

申请号：PCT/US2014/071988

申请日：2014-12-22

申请人： ONEFOCUS VISION, LLC ,  ONEFOCUS VISION, INC.

发明人： WAITE, Steve ,  GUPTA, Amitava ,  SCHNELL, Urban ,  ROULET, Jean-Christophe ,  SAINT-GHISLAIN, Michel ,  TROLLER, Stefan

IPC分类号： G02B3/12

CPC分类号： G02C7/04 ,  G02B3/14 ,  G02C7/085 ,  G02C2202/22

摘要： A meniscus shaped lens module comprises one or more structures that decrease an amount of pressure or force to move one or more surfaces of the lens module and increase a separation distance of anterior and posterior surfaces of the module in order to provide an increase in optical power. A lens structure of the module comprises one or more of a pattern of a surface of a central chamber, a meniscus, a reduced diameter or a soft material in order to provide increased amounts of curvature of an outer contact lens surface with decreased amounts of pressure. The pattern can be formed in one or more of many ways, and may comprise one or more of folds, patterning, bellows or concertinaed surface of an optically transmissive material having a substantially uniform thickness such as a sheet of a membrane material.

摘要翻译： 弯液面形透镜模块包括一个或多个结构，其减少用于移动透镜模块的一个或多个表面的压力或力的量，并增加模块的前表面和后表面的间隔距离，以提供光功率的增加 。 模块的透镜结构包括中心室的表面，弯月面，减小的直径或软材料的图案中的一个或多个，以便以减小的压力量提供增加的外隐形眼镜表面的曲率 。 图案可以以许多方式中的一种或多种形成，并且可以包括具有基本均匀厚度的光学透射材料的折叠，图案化，波纹管或三角形表面中的一个或多个，例如膜材料片。

公开(公告)号：WO2018089699A1

公开(公告)日：2018-05-17

申请号：PCT/US2017/060950

申请日：2017-11-09

申请人： ONEFOCUS VISION, INC.

发明人： WAITE, Steve ,  GUPTA, Amitava ,  ALHAKIMI, Gamil ,  STUDNICKI, Lisa ,  ALHAKIMI, Musa

IPC分类号： G02C7/08 ,  G02C7/02 ,  G02C7/04

CPC分类号： G02C7/049 ,  G02C7/02 ,  G02C7/08

摘要： A lens comprises an internal cavity structure formed by dissolution of a soluble insert material. The internal soluble material may dissolve through a body of a lens such as a contact lens in order to form the cavity within the contact lens. The cavity within the lens can be shaped in many ways and corresponds to the shape of the dissolved material, such that many internal cavity shapes can be readily fabricated within the contact lens. The insert can be placed in a mold with a pre-polymer material, and the pre-polymer material cured with the insert placed in the mold to form the lens body. The polymerized polymer may comprise a low expansion polymer in order to inhibit expansion of the lens when hydrated. The polymer may comprise a hydrogel when hydrated. The soft contact lens material comprises a sufficient amount of cross-linking to provide structure to the lens and shape the cavity.

摘要翻译： 透镜包括通过溶解可溶性插入材料形成的内腔结构。 内部可溶性材料可通过例如隐形眼镜的镜片主体溶解，以在隐形眼镜内形成腔。 透镜内的空腔可以以许多方式成形并且对应于溶解材料的形状，使得许多内部空腔形状可以容易地在隐形眼镜内制造。 插入物可以放置在具有预聚合物材料的模具中，并且将插入物置于模具中固化的预聚物材料形成镜体。 聚合的聚合物可以包含低膨胀聚合物以抑制透镜在水合时膨胀。 当水合时，聚合物可以包含水凝胶。 软性隐形眼镜材料包含足够量的交联以为透镜提供结构并形成空腔。

公开(公告)号：WO2017083771A1

公开(公告)日：2017-05-18

申请号：PCT/US2016/061697

申请日：2016-11-11

申请人： ONEFOCUS VISION, INC.

发明人： PAYOR, Rick ,  GOBRON, Stephane ,  LUBBERMAN, Ben ,  WAITE, Steve

IPC分类号： A61F2/16 ,  B29D11/02 ,  G02B3/12 ,  G02C7/06 ,  G02C7/08

CPC分类号： G02C7/048 ,  B29D11/00028 ,  G02C7/083 ,  G02C7/085

摘要： The stabilized contact lens methods and apparatus disclosed herein provide improved stabilization of a contact lens placed on a cornea of an eye. The contact lens comprises stabilization zones that allow the lens to repeatedly and consistently orient on the cornea such that a sensing zone located on the lower portion of the lens is located inferiorly to engage the lower eyelid. The stabilized contact lens can provide a lower pressure sensing zone with decreased thickness for pressure or other sensing related to the lower eyelid. The decreased thickness has the advantage of improving coupling between forces from an eyelid and a lower chamber of a fluidic module. The improved coupling allows increased amounts of fluid to move between the lower chamber and an upper optical chamber coupled to the lower chamber, such that the upper chamber can increase curvature and optical power in response to pressures of the eyelid.

摘要翻译： 本文公开的稳定化隐形眼镜方法和设备提供了改善的置于眼角膜上的隐形眼镜的稳定性。 隐形眼镜包括稳定区，其允许镜片在角膜上重复且一致地定向，使得位于镜片下部的感测区位于下方以接合下眼睑。 稳定的隐形眼镜可以提供具有减小的厚度的较低压力感测区，用于与下眼睑相关的压力或其他感测。 减小的厚度具有改善来自眼睑和流体模块的下腔室之间的力之间的耦合的优点。 改进的耦合允许增加量的流体在下部腔室和耦合到下部腔室的上部光学腔室之间移动，使得上部腔室可以响应于眼睑的压力而增加曲率和光焦度。