公开(公告)号：WO2017083774A1

公开(公告)日：2017-05-18

申请号：PCT/US2016/061700

申请日：2016-11-11

Applicant: ONEFOCUS VISION, INC. ,  WAITE, Steve

Inventor： WAITE, Steve ,  HARANT, Adam ,  DAVENPORT, Amelia ,  CRAMER, Neil ,  GUPTA, Amitava ,  LINK, William J. ,  ALKHIMI, Gamil ,  STUDNICKI, Lisa ,  ALHAKIMI, Musa

IPC: B29C39/12 ,  B29C41/22 ,  B29D11/00 ,  B29L11/00 ,  C08J3/24 ,  G02B1/04 ,  G02C7/04

CPC classification number: G02C7/049 ,  B29C39/021 ,  B29C39/10 ,  B29C39/12 ,  B29C41/22 ,  B29D11/00 ,  B29D11/00038 ,  B29D11/00048 ,  B29D11/00125 ,  B29D11/00134 ,  B29K2105/0002 ,  B29K2105/0035 ,  B29K2105/20 ,  B29K2629/04 ,  B29K2995/0059 ,  B29L2011/0041 ,  G02B1/04 ,  G02B1/043 ,  G02C7/04 ,  G02C7/048 ,  G02C7/085 ,  C08L101/14 ,  C08L33/10 ,  C08L33/26

Abstract: A lens comprises an internal cavity structure formed by dissolution of a soluble insert material. The internal soluble material may dissolve through a body of a lens such as a contact lens in order to form the cavity within the contact lens. The cavity within the lens can be shaped in many ways, and corresponds to the shape of the dissolved material, such that many internal cavity shapes can be readily fabricated within the contact lens. The insert can be placed in a mold with a pre-polymer material, and the pre-polymer material cured with the insert placed in the mold to form the lens body. The polymerized polymer may comprise a low expansion polymer in order to inhibit expansion of the lens when hydrated. The polymer may comprise a hydrogel when hydrated. The soft contact lens material comprises a sufficient amount of cross-linking to provide structure to the lens and shape the cavity.

Abstract translation: 透镜包括通过溶解可溶性插入材料形成的内腔结构。 内部可溶性材料可通过例如隐形眼镜的镜片主体溶解，以在隐形眼镜内形成腔。 透镜内的空腔可以以许多方式成形，并且对应于溶解材料的形状，使得很多内部空腔形状可以容易地制造在隐形眼镜内。 插入物可以放置在具有预聚合物材料的模具中，并且将插入物置于模具中固化的预聚物材料形成镜体。 聚合的聚合物可以包含低膨胀聚合物以抑制透镜在水合时膨胀。 当水合时，聚合物可以包含水凝胶。 软性隐形眼镜材料包含足够量的交联以为透镜提供结构并形成空腔。

公开(公告)号：WO2017083770A1

公开(公告)日：2017-05-18

申请号：PCT/US2016/061696

申请日：2016-11-11

Applicant: ONEFOCUS VISION, INC.

Inventor： HARANT, Adam ,  CRAMER, Neil ,  DAVENPORT, Amelia ,  WAITE, Steve ,  GUPTA, Amitava

IPC: B29D11/00 ,  G02C7/04

CPC classification number: B29D11/00 ,  B29D11/00028 ,  B29D11/00048 ,  B29D11/00067 ,  G02B1/043 ,  G02C7/04 ,  C08L33/10

Abstract: A hydrogel formulation has been developed that can be cast to form a hydrophilic cross-linked network with water content of 30-60% by weight that undergoes a volume expansion less than 5% when equilibrated in water or an aqueous solution of ionic species. This hydrogel formulation was used to cast a soft contact lens incorporating an insert that may be a sealed module filled with a fluid. Diameter of lenses cast without an insert measured within 0.5-5.0%) of the target diameter after hydration. The interface between the hydrogel and the insert in lenses cast with an insert remaining stress free after hydration, when the lens was inspected under a microscope. The formulation comprises and may consist of a mixture of hydrophilic mono-functional monomers, cross-linking agents, a photo-curing catalyst and a diluent.

Abstract translation: 已经开发了一种水凝胶制剂，其可以浇注以形成水含量为30-60重量％的亲水性交联网络，其在水中平衡时经历小于5％的体积膨胀或 离子物质的水溶液。 使用该水凝胶制剂来铸造包含插入物的软性隐形眼镜，该插入物可以是填充有流体的密封模块。 在没有插入物的情况下铸造的透镜的直径在水合后在0.5-5.0％的目标直径内测量。 当透镜在显微镜下检查时，水凝胶和插入物之间的界面与水合后保持无应力的插入物一起铸造。 该制剂包含亲水性单官能单体，交联剂，光固化催化剂和稀释剂的混合物并可由其组成。