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    COLLECTION CATHETER AND KIT
    1.
    发明申请
    COLLECTION CATHETER AND KIT 审中-公开
    收藏夹和工具包

    公开(公告)号：WO2008057917A2

    公开(公告)日：2008-05-15

    申请号：PCT/US2007/083299

    申请日：2007-11-01

    申请人： OSPREY MEDICAL INC. ,  SHAPLAND, James, Edward ,  DOAN, Tuan ,  BROWN, Mark, Francis

    发明人： SHAPLAND, James, Edward ,  DOAN, Tuan ,  BROWN, Mark, Francis

    IPC分类号： A61B5/15 ,  A61M1/00 ,  A61M25/00 ,  A61M25/10

    CPC分类号： A61M1/0035 ,  A61M1/0031 ,  A61M1/3627 ,  A61M1/3653 ,  A61M1/3659 ,  A61M25/007 ,  A61M25/1002 ,  A61M2025/0031 ,  A61M2025/1052 ,  A61M2025/1093 ,  A61M2025/1095

    摘要： A catheter for collecting fluid such as blood from a vessel such as a coronary sinus of a patient has an elongated, flexible tubular portion and an annular sealing member spaced from a distal end of the tubular member. A proximal end of the tubular member is adapted to be connected to a source of suction for applying suction to a collection lumen of the tubular member. The distal end is placed in a blood vessel with the sealing member spaced from opposing surface of the vessel in an absence of a suction applied to the collection lumen. Suction is applied to the collection lumen in an amount sufficient to draw blood from the vessel through the fluid inlet and into the collection lumen and further sufficient to urge the opposing surface of the vessel to migrate into sealing engagement with the sealing member.

    摘要翻译： 用于从诸如患者的冠状窦的容器收集诸如血液的流体的导管具有细长的柔性管状部分和与管状构件的远端间隔开的环形密封构件。 管状构件的近端适于连接到用于向管状构件的收集腔施加吸力的抽吸源。 远端被放置在血管中，其中密封构件在没有施加到收集腔的抽吸的情况下与容器的相对表面间隔开。 以足以从血管吸入血液通过流体入口并进入收集腔并且进一步足以促使血管的相对表面迁移到与密封构件密封接合的量施加到收集腔。

    ISOLATING CARDIAC CIRCULATION
    2.
    发明申请
    ISOLATING CARDIAC CIRCULATION 审中-公开
    隔离心脏循环

    公开(公告)号：WO2008027272A3

    公开(公告)日：2008-04-17

    申请号：PCT/US2007018628

    申请日：2007-08-23

    申请人： OSPREY MEDICAL INC ,  KAYE DAVID MARTIN ,  ALFERNESS CLIFTON A ,  POWER JOHN M ,  BILNEY ADAM LUCAS

    发明人： KAYE DAVID MARTIN ,  ALFERNESS CLIFTON A ,  POWER JOHN M ,  BILNEY ADAM LUCAS

    IPC分类号： A61B17/00 ,  A61F2/958

    CPC分类号： A61M1/3666 ,  A61B17/12136 ,  A61B2017/00252 ,  A61B2017/22068 ,  A61M1/32 ,  A61M1/3624 ,  A61M1/3653 ,  A61M1/3655 ,  A61M1/3659 ,  A61M25/0074 ,  A61M25/0082 ,  A61M25/1002 ,  A61M25/1011 ,  A61M29/00 ,  A61M2025/0096 ,  A61M2025/1052 ,  A61M2202/07 ,  A61M2202/206 ,  A61M2210/125 ,  A61M2210/127

    摘要： In a method for substantially isolating -cardiac circulation from systemic circulation, flow between the coronary sinus (CS) and the right atrium is occluded using a venous collection device (300, 310, 320, 330, 340, 350) which may have a balloon (302, 342, 344, 352, 354) or a flange (326, 334) to achieve occlusion. The venous collection device has a collection lumen (308) and a support structure (304, 314, 324, 334) and is located in the coronary sinus. The support structure is used to maintain patency of the coronary sinus during collection of fluid through the collection lumen. An artificial flow path is provided between the collection lumen and the one or more coronary arteries, thus isolating the cardiac circulation. According to the method, cardiac pumping for systemic circulation can be maintained during isolation of the cardiac circulation. This allows drugs to be administered to the heart without being degraded by passing through the liver.

    摘要翻译： 在用于从体循环中基本分离心脏循环的方法中，使用静脉收集装置（300,310,320,330,340,350）封闭冠状窦（CS）和右心房之间的流动，所述静脉收集装置（300,310,320,330,340,350）可具有球囊 （302,342,344,352,354）或凸缘（326,334）以实现闭塞。 静脉收集装置具有收集腔（308）和支撑结构（304,314,324,334），并且位于冠状窦中。 支撑结构用于在通过收集腔收集流体期间保持冠状窦的通畅。 在收集腔和一个或多个冠状动脉之间提供人造流路，从而隔离心脏循环。 根据该方法，可以在分离心脏循环期间维持心脏泵送全身循环。 这允许将药物施用于心脏而不会通过穿过肝脏而被降解。

    COLLECTION CATHETER AND KIT
    5.
    发明申请
    COLLECTION CATHETER AND KIT 审中-公开
    收藏夹和工具包

    公开(公告)号：WO2008057917A3

    公开(公告)日：2008-07-31

    申请号：PCT/US2007083299

    申请日：2007-11-01

    申请人： OSPREY MEDICAL INC ,  SHAPLAND JAMES EDWARD ,  DOAN TUAN ,  BROWN MARK FRANCIS

    发明人： SHAPLAND JAMES EDWARD ,  DOAN TUAN ,  BROWN MARK FRANCIS

    IPC分类号： A61B5/15 ,  A61F2/958 ,  A61M1/00 ,  A61M25/00

    CPC分类号： A61M1/0035 ,  A61M1/0031 ,  A61M1/3627 ,  A61M1/3653 ,  A61M1/3659 ,  A61M25/007 ,  A61M25/1002 ,  A61M2025/0031 ,  A61M2025/1052 ,  A61M2025/1093 ,  A61M2025/1095

    摘要： A catheter (10) for collecting fluid such as blood from a vessel such as a coronary sinus of a patient has an elongated, flexible tubular portion (12) and an annular sealing member (18) spaced from a distal end of the tubular member. A proximal end of the tubular member is adapted to be connected to a source of suction (111) for applying suction to a collection lumen of the tubular member. The distal end (16) is placed in a blood vessel with the sealing member spaced from opposing surface of the vessel in an absence of a suction applied to the collection lumen. Suction is applied to the collection lumen in an amount sufficient to draw blood from the vessel through the fluid inlet and into the collection lumen and further sufficient to urge the opposing surface of the vessel to migrate into sealing engagement with the sealing member.

    摘要翻译： 用于从诸如患者的冠状窦的容器收集诸如血液的流体的导管（10）具有细长的柔性管状部分（12）和与管状构件的远端间隔开的环形密封构件（18）。 管状构件的近端适于连接到用于向管状构件的收集腔施加抽吸的抽吸源（111）。 远端（16）被放置在血管中，其中密封构件在不存在施加到收集腔的抽吸的情况下与容器的相对表面间隔开。 以足以从血管吸入血液通过流体入口并进入收集腔并且进一步足以促使血管的相对表面迁移到与密封构件密封接合的量施加到收集腔。

    SYSTEMS AND METHODS FOR LIMB TREATMENT
    9.
    发明申请
    SYSTEMS AND METHODS FOR LIMB TREATMENT 审中-公开
    用于肢体治疗的系统和方法

    公开(公告)号：WO2013023126A3

    公开(公告)日：2013-04-25

    申请号：PCT/US2012050277

    申请日：2012-08-10

    申请人： OSPREY MEDICAL INC ,  KAYE DAVID MARTIN

    发明人： KAYE DAVID MARTIN

    IPC分类号： A61M25/01 ,  A61M1/36 ,  A61M5/142 ,  A61M37/00

    CPC分类号： A61M1/3659 ,  A61M1/1698 ,  A61M1/3621 ,  A61M5/142 ,  A61M25/10 ,  A61M2025/1095 ,  A61M2202/0021 ,  A61M2210/086 ,  A61M2210/12

    摘要： A method of delivering a medicament to a limb of a patient body includes isolating a circulatory system of the limb from a circulatory system of the patient body, wherein the limb circulatory system is substantially all limb arteries and substantially all limb veins located between an isolation region and an end of the limb. A perfusion catheter is inserted into a limb artery in an antegrade position, while a collection catheter is inserted into a limb vein in a retrograde position. The blood flow of the limb circulatory system is then circulated by collecting the blood flow with the collection catheter and delivering the blood flow with the perfusion catheter. A medicament is perfused into the limb circulatory system with the perfusion catheter.

    摘要翻译： 将药物输送到患者身体的肢体的方法包括将肢体的循环系统与患者身体的循环系统隔离，其中肢体循环系统基本上是全部肢体动脉并且基本上全部肢体静脉位于隔离区域 和肢体的一端。 将灌注导管以顺行位置插入肢体动脉中，同时将收集导管以倒退位置插入肢体静脉中。 然后通过用收集导管收集血流并用灌注导管输送血流来使肢体循环系统的血流循环。 用灌注导管将药物灌注到肢体循环系统中。

    SYSTEMS AND METHODS FOR LIMB TREATMENT
    10.
    发明申请
    SYSTEMS AND METHODS FOR LIMB TREATMENT 审中-公开
    LIMB治疗系统与方法

    公开(公告)号：WO2013023126A2

    公开(公告)日：2013-02-14

    申请号：PCT/US2012/050277

    申请日：2012-08-10

    申请人： OSPREY MEDICAL INC. ,  KAYE, David, Martin

    发明人： KAYE, David, Martin

    IPC分类号： A61M25/01 ,  A61M5/142 ,  A61M1/36 ,  A61M37/00

    CPC分类号： A61M1/3659 ,  A61M1/1698 ,  A61M1/3621 ,  A61M5/142 ,  A61M25/10 ,  A61M2025/1095 ,  A61M2202/0021 ,  A61M2210/086 ,  A61M2210/12

    摘要： A method of delivering a medicament to a limb of a patient body includes isolating a circulatory system of the limb from a circulatory system of the patient body, wherein the limb circulatory system is substantially all limb arteries and substantially all limb veins located between an isolation region and an end of the limb. A perfusion catheter is inserted into a limb artery in an antegrade position, while a collection catheter is inserted into a limb vein in a retrograde position. The blood flow of the limb circulatory system is then circulated by collecting the blood flow with the collection catheter and delivering the blood flow with the perfusion catheter. A medicament is perfused into the limb circulatory system with the perfusion catheter.

    摘要翻译： 将药物递送到患者身体的肢体的方法包括将肢体的循环系统与患者体的循环系统隔离，其中肢体循环系统基本上都是肢体动脉，并且基本上所有的肢体静脉位于隔离区域 和肢体的一端。 将灌注导管插入到顺行位置的肢体动脉中，同时将收集导管插入到逆行位置的肢体静脉中。 然后通过收集导管收集血流并用灌注导管输送血流来循环肢体循环系统的血液流量。 用灌注导管将药物灌注到肢体循环系统中。