公开(公告)号：WO2002078646A1

公开(公告)日：2002-10-10

申请号：PCT/US2001/046526

申请日：2001-12-05

Applicant: PENTRON CORPORATION

Inventor： JIA, Weitao ,  JIN, Shuhua

IPC: A61K6/083

CPC classification number: A61L27/446 ,  A61K6/0032 ,  A61K6/0038 ,  A61K6/0082 ,  A61K6/0091 ,  A61K6/083 ,  A61K6/087 ,  A61L24/04 ,  A61L27/46 ,  A61L2430/12 ,  C08L29/04 ,  C08L67/07 ,  C08L33/00 ,  C08L67/04

Abstract: Curable compositions comprising degradable macromonomers having one or more terminal acrylate or methacrylate functionality, a curing composition, a filler composition comprising bioactive particles of bioactive glass, bioactive glass-ceramics, calcium phosphates, calcium appetites, or mixtures thereof and optionally one or more polymerizable acrylate or methacrylate comonomers. Degradable macromonomers are manufactured from cyclic monomers with compounds having acrylate or methacrylate functionality. Depending on their use, the degradable macromonomer compositions further comprise one or more organic or inorganic fillers, including a calcium-based compound and/or a radiopacity-imparting agent. The compositions are particularly suitable for root canal sealants, implants, bone cements, and pulp capping materials.

Abstract translation: 包含具有一个或多个末端丙烯酸酯或甲基丙烯酸酯官能团的可降解大分子单体的固化组合物，固化组合物，包含生物活性玻璃的生物活性颗粒，生物活性玻璃 - 陶瓷，磷酸钙，钙食欲或其混合物的填料组合物和任选的一种或多种可聚合丙烯酸酯 或甲基丙烯酸酯共聚单体。 可降解的大分子单体由具有丙烯酸酯或甲基丙烯酸酯官能团的化合物的环状单体制备。 根据其用途，可降解大分子组合物还包含一种或多种有机或无机填料，包括钙基化合物和/或不透射线渗透剂。 该组合物特别适用于根管密封剂，植入物，骨水泥和纸浆覆盖材料。