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公开(公告)号:WO2010102251A2
公开(公告)日:2010-09-10
申请号:PCT/US2010/026424
申请日:2010-03-05
Applicant: ABBOTT LABORATORIES , HSIEH, Chung-Ming , HUGUNIN, Margaret , MURTAZA, Anwar , McRAE, Bradford, L. , KUTSKOVA, Yuliya , MEMMOTT, John, E. , PEREZ, Jennifer, M. , ZHONG, Suju , TARCSA, Edit , CLABBERS, Anca , WALLACE, Craig , BRYANT, Shaughn, H. , LEDDY, Mary, R.
Inventor: HSIEH, Chung-Ming , HUGUNIN, Margaret , MURTAZA, Anwar , McRAE, Bradford, L. , KUTSKOVA, Yuliya , MEMMOTT, John, E. , PEREZ, Jennifer, M. , ZHONG, Suju , TARCSA, Edit , CLABBERS, Anca , WALLACE, Craig , BRYANT, Shaughn, H. , LEDDY, Mary, R.
IPC: A61K39/395
CPC classification number: C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/466
Abstract: Proteins that bind IL- 17 and/or IL- 17F are described along with there use in composition and methods for treating, preventing, and diagnosing IL- 17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
Abstract translation: 与用于治疗,预防和诊断IL-17相关疾病和检测细胞,组织,样品和组合物中的IL-17的组合物和方法一起描述了结合IL-17和/或IL-17F的蛋白质。
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公开(公告)号:WO2009114093A2
公开(公告)日:2009-09-17
申请号:PCT/US2009/001351
申请日:2009-03-03
Applicant: ABBOTT LABORATORIES , HSIEH, Chung-ming , BELK, Jonathan, P. , PEREZ, Jennifer, M. , BENATUIL, Lorenzo
Inventor: HSIEH, Chung-ming , BELK, Jonathan, P. , PEREZ, Jennifer, M. , BENATUIL, Lorenzo
Abstract: This invention is directed to the transformation of yeast, and mutants thereof, by electroporation, which result in stably transformed yeast host cells that express recombinant products. This invention also is directed to transformed yeast cells and libraries.
Abstract translation: 本发明涉及通过电穿孔转化酵母及其突变体,其导致表达重组产物的稳定转化的酵母宿主细胞。 本发明还涉及转化的酵母细胞和文库。
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3.COMPOSITION AND METHOD FOR THE DIAGNOSIS AND TREATMENT OF IRON-RELATED DISORDERS 审中-公开
Title translation: 用于诊断和治疗相关疾病的组合物和方法公开(公告)号:WO2013090635A3
公开(公告)日:2013-09-26
申请号:PCT/US2012069586
申请日:2012-12-13
Applicant: ABBVIE DEUTSCHLAND , ABBVIE INC , MUELLER BERNHARD , POPP ANDREAS , PEREZ JENNIFER M
Inventor: MUELLER BERNHARD , POPP ANDREAS , PEREZ JENNIFER M
IPC: C07K16/26 , A61K39/395 , C07K16/28
CPC classification number: C07K16/18 , A61K2039/505 , C07K16/28 , C07K2317/24 , C07K2317/565 , C07K2317/92 , G01N33/566
Abstract: Provided herein are methods of using the antibodies that bind to RGMc to treat and diagnose iron-related disorders.
Abstract translation: 本文提供了使用结合RGMc的抗体来治疗和诊断铁相关疾病的方法。
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4.COMPOSITION AND METHOD FOR THE DIAGNOSIS AND TREATMENT OF IRON-RELATED DISORDERS 审中-公开
Title translation: 用于诊断和治疗铁相关病症的组合物和方法公开(公告)号:WO2013090635A2
公开(公告)日:2013-06-20
申请号:PCT/US2012/069586
申请日:2012-12-13
Applicant: ABBVIE DEUTSCHLAND GMBH & CO. KG , ABBVIE INC. , MUELLER, Bernhard , POPP, Andreas , PEREZ, Jennifer M.
Inventor: MUELLER, Bernhard , POPP, Andreas , PEREZ, Jennifer M.
IPC: C07K16/26 , C07K16/28 , A61K39/395
CPC classification number: C07K16/18 , A61K2039/505 , C07K16/28 , C07K2317/24 , C07K2317/565 , C07K2317/92 , G01N33/566
Abstract: Provided herein are methods of using the antibodies that bind to RGMc to treat and diagnose iron-related disorders.
Abstract translation: 本文提供了使用结合RGMc的抗体来治疗和诊断铁相关病症的方法。 p> u>
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公开(公告)号:WO2009114093A3
公开(公告)日:2010-01-21
申请号:PCT/US2009001351
申请日:2009-03-03
Applicant: ABBOTT LAB , HSIEH CHUNG-MING , BELK JONATHAN P , PEREZ JENNIFER M , BENATUIL LORENZO
Inventor: HSIEH CHUNG-MING , BELK JONATHAN P , PEREZ JENNIFER M , BENATUIL LORENZO
Abstract: This invention is directed to the transformation of yeast, and mutants thereof, by electroporation, which result in stably transformed yeast host cells that express recombinant products. This invention also is directed to transformed yeast cells and libraries.
Abstract translation: 本发明涉及通过电穿孔转化酵母及其突变体,其导致表达重组产物的稳定转化的酵母宿主细胞。 本发明还涉及转化的酵母细胞和文库。
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公开(公告)号:WO2010102251A3
公开(公告)日:2010-11-25
申请号:PCT/US2010026424
申请日:2010-03-05
Applicant: ABBOTT LAB , HSIEH CHUNG-MING , HUGUNIN MARGARET , MURTAZA ANWAR , MCRAE BRADFORD L , KUTSKOVA YULIYA , MEMMOTT JOHN E , PEREZ JENNIFER M , ZHONG SUJU , TARCSA EDIT , CLABBERS ANCA , WALLACE CRAIG , BRYANT SHAUGHN H , LEDDY MARY R
Inventor: HSIEH CHUNG-MING , HUGUNIN MARGARET , MURTAZA ANWAR , MCRAE BRADFORD L , KUTSKOVA YULIYA , MEMMOTT JOHN E , PEREZ JENNIFER M , ZHONG SUJU , TARCSA EDIT , CLABBERS ANCA , WALLACE CRAIG , BRYANT SHAUGHN H , LEDDY MARY R
IPC: A61K39/395
CPC classification number: C07K16/468 , A61K39/3955 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/241 , C07K16/244 , C07K2317/21 , C07K2317/31 , C07K2317/50 , C07K2317/565 , C07K2317/64 , C07K2317/76 , C07K2317/92
Abstract: Proteins that bind IL- 17 and/or IL- 17F are described along with there use in composition and methods for treating, preventing, and diagnosing IL- 17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.
Abstract translation: 描述了结合IL-17和/或IL-17F的蛋白以及其在用于治疗,预防和诊断IL-17相关疾病和检测细胞,组织,样品和组合物中的IL-17的组合物和方法中的应用。
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