公开(公告)号：WO2005009214A2

公开(公告)日：2005-02-03

申请号：PCT/US2004/022839

申请日：2004-07-15

Applicant: LUMEN BIOMEDICAL, INC. ,  GALDONIK, Jason, A. ,  OGLE, Matthew, F. ,  POKORNEY, Jim ,  HINNENKAMP, Thomas, F.

Inventor： GALDONIK, Jason, A. ,  OGLE, Matthew, F. ,  POKORNEY, Jim ,  HINNENKAMP, Thomas, F.

IPC: A61B

CPC classification number: A61F2/01 ,  A61F2/013 ,  A61F2230/0006 ,  A61F2230/005 ,  A61M25/09 ,  A61M2025/09175 ,  B33Y80/00

Abstract: Improved embolism protection devices comprises fibers that can have one configuration for delivery of the device and a second configuration in which the device is deployed for filtering of flow within a vessel. In some embodiments, the fibers can be connected to a fiber support, which is connected to an actuating element. The actuating element controls the transition from the delivery configuration to the deployed configuration. The embolism protection device can comprise a guidewire. The fibers can be attached at one end to a fiber support structure and at another end to the guidewire. A hypotube can be attached to the proximal end of the fibers while the guidewire is attached at the distal end of the fibers with the guidewire extending within a central channel of the hypotube. The hypotube can be used to guide the delivery of treatment structures, such as a balloon and/or a stent.

Abstract translation: 改进的栓塞保护装置包括可以具有用于装置的输送的一种配置的纤维和其中部署用于过滤容器内的流动的装置的第二配置。 在一些实施例中，纤维可以连接到连接到致动元件的纤维支撑件。 致动元件控制从传送配置到部署配置的过渡。 栓塞保护装置可以包括导丝。 纤维的一端可以连接到纤维支撑结构，另一端可以连接到导丝。 海波管可以附着在纤维的近端，而导丝被连接在纤维的远端，导丝延伸在海波管的中心通道内。 海波管可用于引导治疗结构的传送，例如气囊和/或支架。

公开(公告)号：WO2005118050A2

公开(公告)日：2005-12-15

申请号：PCT/US2005018334

申请日：2005-05-24

Applicant: LUMEN BIOMEDICAL INC ,  GALDONIK JASON A ,  OGLE MATTHEW F ,  POKORNEY JIM

Inventor： GALDONIK JASON A ,  OGLE MATTHEW F ,  POKORNEY JIM

IPC: A61B17/22 ,  A61F2/01 ,  A61M1/00 ,  A61M29/00

CPC classification number: A61B17/22 ,  A61B2017/22034 ,  A61B2017/22035 ,  A61B2017/22079 ,  A61B2217/005 ,  A61F2/01

Abstract: Methods for the removal of an embolism protection device use aspiration during the drawing of the embolism protection device into the catheter. Generally, the embolism protection device comprises a three dimensional filtering matrix that provides improved filtering without blocking the flow through the patient's vessel. In some embodiments, the embolism protection device can be actuated between a deployed configuration and a removal configuration with a reduced area across the cross section of the vessel lumen. The embolism protection device in the removal configuration can be drawn within the aspiration catheter. The aspiration catheter can have a distal portion with an expanded compartment with an average diameter at least about 20 percent larger than the average diameter of the shaft of the catheter within about 10 centimeters of the expanded compartment. In a rapid exchange version, the rapid exchange segment can have a length of at least about 10 centimeters.

Abstract translation: 在将栓塞保护装置拉入导管期间，用于去除栓塞保护装置的方法使用抽吸。 通常，栓塞保护装置包括三维过滤矩阵，其提供改进的过滤而不阻塞通过患者血管的流动。 在一些实施例中，栓塞保护装置可以在展开构造和移除构造之间被致动，并且在血管内腔的横截面上具有减小的面积。 拔除结构中的栓塞保护装置可以在抽吸导管内拉出。 抽吸导管可以具有远端部分，其具有扩张隔室，平均直径比扩张隔室的约10厘米内的导管轴的平均直径至少大约20％。 在快速交换版本中，快速交换段可以具有至少约10厘米的长度。

公开(公告)号：WO2005086796A2

公开(公告)日：2005-09-22

申请号：PCT/US2005/007511

申请日：2005-03-07

Applicant: LUMEN BIOMEDICAL, INC. ,  GALDONIK, Jason, A. ,  POKORNEY, Jim ,  OGLE, Matthew, F.

Inventor： GALDONIK, Jason, A. ,  POKORNEY, Jim ,  OGLE, Matthew, F.

IPC: A61M25/00 ,  A61M25/01

CPC classification number: A61M25/0138 ,  A61M25/0054 ,  A61M25/0133

Abstract: An integrated guiding device has a tube and a corewire within the tube and a torque coupler. The torque coupler can couple the rotational motion of the tube with the rotational motion of the corewire. The wire can be moved longitudinally at least some amount relative to the tube. The device can further comprise a functional medical structure, such as an embolism protection structure. The device can be used in medical procedures, such as less invasive procedures within the cardiovascular system. Improved fiber based embolism protection devices comprise fiber bundles that are twisted prior to delivery.

Abstract translation: 集成引导装置在管内具有管和芯线，以及扭矩耦合器。 扭矩耦合器可将管的旋转运动与芯线的旋转运动耦合。 电线可以相对于管子至少一定数量的纵向移动。 该装置还可以包括诸如栓塞保护结构的功能医疗结构。 该装置可用于医疗程序，例如心血管系统内的侵入性较小的程序。 改进的基于纤维的栓塞保护装置包括在输送之前被扭曲的纤维束。

公开(公告)号：WO2005118050A3

公开(公告)日：2005-12-15

申请号：PCT/US2005/018334

申请日：2005-05-24

Applicant: LUMEN BIOMEDICAL, INC. ,  GALDONIK, Jason, A. ,  OGLE, Matthew, F. ,  POKORNEY, Jim

Inventor： GALDONIK, Jason, A. ,  OGLE, Matthew, F. ,  POKORNEY, Jim

IPC: A61B17/32

Abstract: Methods for the removal of an embolism protection device use aspiration during the drawing of the embolism protection device into the catheter. Generally, the embolism protection device comprises a three dimensional filtering matrix that provides improved filtering without blocking the flow through the patient's vessel. In some embodiments, the embolism protection device can be actuated between a deployed configuration and a removal configuration with a reduced area across the cross section of the vessel lumen. The embolism protection device in the removal configuration can be drawn within the aspiration catheter. The aspiration catheter can have a distal portion with an expanded compartment with an average diameter at least about 20 percent larger than the average diameter of the shaft of the catheter within about 10 centimeters of the expanded compartment. In a rapid exchange version, the rapid exchange segment can have a length of at least about 10 centimeters.

公开(公告)号：WO2005009214A3

公开(公告)日：2005-11-10

申请号：PCT/US2004022839

申请日：2004-07-15

Applicant: LUMEN BIOMEDICAL INC ,  GALDONIK JASON A ,  OGLE MATTHEW F ,  POKORNEY JIM ,  HINNENKAMP THOMAS F

Inventor： GALDONIK JASON A ,  OGLE MATTHEW F ,  POKORNEY JIM ,  HINNENKAMP THOMAS F

IPC: A61B20060101 ,  A61M25/09 ,  A61M25/12 ,  A61M29/00 ,  G02B6/00

CPC classification number: A61F2/01 ,  A61F2/013 ,  A61F2230/0006 ,  A61F2230/005 ,  A61M25/09 ,  A61M2025/09175 ,  B33Y80/00

Abstract: Improved embolism protection devices comprises fibers that can have one configuration for delivery of the device and a second configuration in which the device is deployed for filtering of flow within a vessel. In some embodiments, the fibers can be connected to a fiber support, which is connected to an actuating element. The actuating element controls the transition from the delivery configuration to the deployed configuration. The embolism protection device can comprise a guidewire. The fibers can be attached at one end to a fiber support structure and at another end to the guidewire. A hypotube can be attached to the proximal end of the fibers while the guidewire is attached at the distal end of the fibers with the guidewire extending within a central channel of the hypotube. The hypotube can be used to guide the delivery of treatment structures, such as a balloon and/or a stent.

Abstract translation: 改进的栓塞保护装置包括可具有用于输送装置的一种配置的纤维和配置装置以用于过滤血管内的流的第二配置。 在一些实施例中，纤维可以连接到连接到致动元件的纤维支撑件。 执行元件控制从传送配置到展开配置的转换。 栓塞保护装置可以包括导丝。 纤维可以一端连接到纤维支撑结构，另一端连接到导丝。 海波管可以连接到纤维的近端，而导丝连接在纤维的远端，而导丝在海波管的中心通道内延伸。 海波管可用于引导治疗结构如气球和/或支架的输送。

公开(公告)号：WO2007050683A3

公开(公告)日：2007-07-12

申请号：PCT/US2006041630

申请日：2006-10-23

Applicant: SPECTRASCIENCE INC ,  SIEVERT CHET ,  WILSON SCOTT ,  ZIMMERMAN RON ,  POKORNEY JIM

Inventor： SIEVERT CHET ,  WILSON SCOTT ,  ZIMMERMAN RON ,  POKORNEY JIM

IPC: A61B18/18

CPC classification number: A61B5/0084 ,  A61B5/0075 ,  A61B5/6855 ,  A61B18/1492 ,  A61B2017/00061 ,  A61B2018/2238

Abstract: A catheter has an elongated catheter shaft adapted for introduction into a body passageway of a patient. At least one optical fiber extends through the catheter shaft. The optical fiber has a distal end positioned at or near a distal end of the catheter for illuminating tissue and receiving light energy from tissue at the location of the distal end of the tip. A distal region of the catheter includes a deformed portion having a crest offset from a longitudinal axis of the catheter shaft. A distal tip of the optical fiber is positioned at the crest to increases the likelihood of the distal tip contacting tissue of a wall of the body passageway.

Abstract translation: 导管具有适于引入患者身体通道的细长导管轴。 至少一根光纤延伸穿过导管轴。 光纤具有定位在导管的远端处或附近的远端，用于照射组织并且从末端的远端的位置处的组织接收光能。 导管的远侧区域包括具有从导管轴的纵向轴线偏移的顶部的变形部分。 光纤的远侧末端位于顶部以增加远侧末端接触身体通道的壁的组织的可能性。

公开(公告)号：WO2005086796A3

公开(公告)日：2006-08-17

申请号：PCT/US2005007511

申请日：2005-03-07

Applicant: LUMEN BIOMEDICAL INC ,  GALDONIK JASON A ,  POKORNEY JIM ,  OGLE MATTHEW F

Inventor： GALDONIK JASON A ,  POKORNEY JIM ,  OGLE MATTHEW F

IPC: A61M39/00 ,  A61M25/00 ,  A61M25/01

CPC classification number: A61M25/0138 ,  A61M25/0054 ,  A61M25/0133

Abstract: An integrated guiding device has a tube and a corewire within the tube and a torque coupler. The torque coupler can couple the rotational motion of the tube with the rotational motion of the corewire. The wire can be moved longitudinally at least some amount relative to the tube. The device can further comprise a functional medical structure, such as an embolism protection structure. The device can be used in medical procedures, such as less invasive procedures within the cardiovascular system. Improved fiber based embolism protection devices comprise fiber bundles that are twisted prior to delivery.

Abstract translation: 集成引导装置在管内具有管和芯线，以及扭矩耦合器。 扭矩耦合器可将管的旋转运动与芯线的旋转运动耦合。 电线可以相对于管子至少一定数量的纵向移动。 该装置还可以包括诸如栓塞保护结构的功能医疗结构。 该装置可用于医疗程序，例如心血管系统内的侵入性较小的程序。 改进的基于纤维的栓塞保护装置包括在输送之前被扭曲的纤维束。

公开(公告)号：WO2007050683A2

公开(公告)日：2007-05-03

申请号：PCT/US2006/041630

申请日：2006-10-23

Applicant: SPECTRASCIENCE, INC. ,  SIEVERT, Chet ,  WILSON, Scott ,  ZIMMERMAN, Ron ,  POKORNEY, Jim

Inventor： SIEVERT, Chet ,  WILSON, Scott ,  ZIMMERMAN, Ron ,  POKORNEY, Jim

IPC: A61B5/00

CPC classification number: A61B5/0084 ,  A61B5/0075 ,  A61B5/6855 ,  A61B18/1492 ,  A61B2017/00061 ,  A61B2018/2238

Abstract: A catheter has an elongated catheter shaft adapted for introduction into a body passageway of a patient. At least one optical fiber extends through the catheter shaft. The optical fiber has a distal end positioned at or near a distal end of the catheter for illuminating tissue and receiving light energy from tissue at the location of the distal end of the tip. A distal region of the catheter includes a deformed portion having a crest offset from a longitudinal axis of the catheter shaft. A distal tip of the optical fiber is positioned at the crest to increases the likelihood of the distal tip contacting tissue of a wall of the body passageway.

Abstract translation: 导管具有适于引入患者身体通道的细长导管轴。 至少一根光纤延伸穿过导管轴。 光纤具有位于导管的远端处或附近的远端，用于照射组织并从尖端远端位置处的组织接收光能。 导管的远侧区域包括具有从导管轴的纵向轴线偏移的波峰的变形部分。 光纤的远端位于峰顶处，以增加远侧末梢接触身体通道的壁的组织的可能性。