公开(公告)号：WO2007110779A8

公开(公告)日：2008-01-31

申请号：PCT/IB2007001756

申请日：2007-03-29

Applicant: INVERNESS MEDICAL SWITZERLAND ,  LOWE PHILLIP ,  KEATCH STEVEN ALEXANDER ,  HOWELL STEVEN ,  MARQUORDT CLAUS ,  POLWART RUTH ,  THOMSON ALAN KENNETH

Inventor： LOWE PHILLIP ,  KEATCH STEVEN ALEXANDER ,  HOWELL STEVEN ,  MARQUORDT CLAUS ,  POLWART RUTH ,  THOMSON ALAN KENNETH

IPC: B01L3/00 ,  C12Q1/68 ,  G01N33/53

CPC classification number: G01N33/558 ,  B01L3/5027 ,  B01L3/502715 ,  B01L3/502761 ,  B01L3/502769 ,  B01L9/527 ,  B01L2200/0621 ,  B01L2200/0668 ,  B01L2300/0636 ,  B01L2300/0645 ,  B01L2300/0672 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/0887 ,  B01L2400/0406 ,  B01L2400/0683 ,  B01L2400/0688 ,  B01L2400/086 ,  G01N33/54326 ,  G01N33/54366 ,  G01N35/0098

Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid-liquid interface to the second liquid. The magnetically susceptible particles are configured to transport an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.

公开(公告)号：WO2007110779A2

公开(公告)日：2007-10-04

申请号：PCT/IB2007/001756

申请日：2007-03-29

Applicant: INVERNESS MEDICAL SWITZERLAND GMBH ,  LOWE, Phillip ,  KEATCH, Steven, Alexander ,  HOWELL, Steven ,  MARQUORDT, Claus ,  POLWART, Ruth ,  THOMSON, Alan, Kenneth

Inventor： LOWE, Phillip ,  KEATCH, Steven, Alexander ,  HOWELL, Steven ,  MARQUORDT, Claus ,  POLWART, Ruth ,  THOMSON, Alan, Kenneth

CPC classification number: G01N33/558 ,  B01L3/5027 ,  B01L3/502715 ,  B01L3/502761 ,  B01L3/502769 ,  B01L9/527 ,  B01L2200/0621 ,  B01L2200/0668 ,  B01L2300/0636 ,  B01L2300/0645 ,  B01L2300/0672 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/0887 ,  B01L2400/0406 ,  B01L2400/0683 ,  B01L2400/0688 ,  B01L2400/086 ,  G01N33/54326 ,  G01N33/54366 ,  G01N35/0098

Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid-liquid interface to the second liquid. The magnetically susceptible particles are configured to transport an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.

Abstract translation: 测定方法和装置可以在样品液体的单个等分试样上进行至少一个（例如，至少两个）测定。 该装置可以将样品液体与包含磁敏感颗粒的测定试剂混合。 该装置被配置为产生与样品液体的样品液 - 空界面。 当第二液体接触界面以形成液 - 液界面时，磁敏感颗粒可以在液 - 空界面处（通过施加的磁场）定位。 磁性颗粒穿过液体 - 液体界面移动到第二液体。 磁敏感颗粒被配置成将分析物通过界面输送到第二液体中。 在第二液体中进行分析物的测定。 也可以在样品液体中进行另一分析物的测定。

公开(公告)号：WO2009044088A1

公开(公告)日：2009-04-09

申请号：PCT/GB2007/003738

申请日：2007-10-02

Applicant: INVERNESS MEDICAL SWITZERLAND GMBH ,  DILLEEN, John, William ,  LOWE, Phillip ,  POLWART, Ruth ,  HAY, Jennifer ,  MARQUORDT, Claus ,  KEATCH, Steven, Alexander ,  HOWELL, Steven ,  THOMPSON, Alan

Inventor： DILLEEN, John, William ,  LOWE, Phillip ,  POLWART, Ruth ,  HAY, Jennifer ,  MARQUORDT, Claus ,  KEATCH, Steven, Alexander ,  HOWELL, Steven ,  THOMPSON, Alan

IPC: B01L3/00 ,  G01N33/543

CPC classification number: B01L3/5027 ,  B01L3/502761 ,  B01L2200/0647 ,  B01L2200/14 ,  B01L2200/148 ,  B01L2300/0645 ,  B01L2300/0864 ,  B01L2300/0887 ,  B01L2400/043 ,  B01L2400/0688

Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid:liquid interface to the second liquid. The magnetically susceptible particles are configured to transport an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.

Abstract translation: 测定方法和装置可以在样品液体的单个等分试样上进行至少一个（例如，至少两个）测定。 该装置可以将样品液体与包含磁敏感颗粒的测定试剂混合。 该装置被配置为产生与样品液体的样品液 - 空界面。 当第二液体接触界面以形成液 - 液界面时，磁敏感颗粒可以在液 - 空界面处（通过施加的磁场）定位。 磁性颗粒穿过液体：与第二液体的液体界面。 磁敏感颗粒被配置成将分析物通过界面输送到第二液体中。 在第二液体中进行分析物的测定。 也可以在样品液体中进行另一分析物的测定。